Clinical Trials
Braintumor Website

 For People with Newly Diagnosed Glioblastoma Multiforme
A Study of ABT-414 in Subjects With Newly Diagnosed Glioblastoma (GBM)
With Epidermal Growth Factor Receptor (EGFR) Amplification

 For People with Reccurent Glioblastoma Multiforme (and other malignant gliomas)
A Study of ABT-414 in Adult or Pediatric Subjects With Recurrent Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification
Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Glioblastoma at First Recurrence or Progression
Aldoxorubicin Trial for recurrent GBM.

These trials were the most recently added or updated

NCT Trial Name# of CentersLast Updated

NCT03220035

  Pediatric MATCH: Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations
3912/06/2017

NCT03213704

  Pediatric MATCH: Trk Inhibitor LOXO-101 in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions
4012/06/2017

NCT03213678

  Pediatric MATCH: PI3K/mTOR Inhibitor LY3023414 in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations
4012/06/2017

NCT03210714

  Pediatric MATCH: Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations
1712/06/2017

NCT03190967

  T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery
112/06/2017

NCT03155620

  Pediatric MATCH: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders
4712/06/2017

NCT02851706

  Natural History of and Specimen Banking for People With Tumors of the Central Nervous System
112/06/2017

NCT02831959

  Effect of TTFields (150 kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-10 Brain Metastases Following Radiosurgery (METIS)
5912/06/2017

NCT02617589

  An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
6112/06/2017

NCT02414165

  The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma
812/06/2017

NCT03246113

  Tolerability of Cannabis in Patients Receiving Concurrent Chemoradiation for Glioblastoma
112/05/2017

NCT02626364

  Study of Crenolanib in Recurrent/Refractory Glioblastoma With PDGFRA Gene Amplification
112/05/2017

NCT00935090

  3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
112/05/2017

NCT03324360

  Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS)
112/04/2017

NCT03297125

  Assessment of Optune Therapy for Patients With Newly Diagnosed Glioblastoma Using Advanced MRI
112/04/2017

NCT03233204

  Pediatric MATCH: Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes
2812/04/2017

NCT03213665

  Pediatric MATCH: Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations
2612/04/2017

NCT03149575

  VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM
412/04/2017

NCT02780804

  Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
1912/04/2017

NCT02709889

  Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors
2812/04/2017

NCT02580045

  Pharmacokinetics of Systemic Anti-Cancer Therapies in the Cerebrospinal Fluid (CSF) of Patients With Advanced Cancer
112/04/2017

NCT02095132

  WEE1 Inhibitor MK-1775 and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
112/04/2017

NCT01922076

  WEE1 Inhibitor AZD1775 and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
1912/04/2017

NCT01622868

  Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer
11012/04/2017

NCT01505569

  Auto Transplant for High Risk or Relapsed Solid or CNS Tumors
112/03/2017

NCT03361033

  Components of Social Functioning in Survivors of Pediatric Brain Tumors
112/01/2017

NCT03234595

  A Phase I/IIa Study of Cerebraca Wafer Plus Adjuvant Temozolomide (TMZ) in Patients With Recurrent High Grade Glioma
112/01/2017

NCT03043391

  Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children
112/01/2017

NCT02715609

  Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma
112/01/2017

NCT02713087

  Vasopressor Effects in Anesthetized Patients
112/01/2017

NCT02663271

  TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma
212/01/2017

NCT02367469

  Tryptophan Metabolism in Human Brain Tumors
112/01/2017

NCT02142803

  TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors
212/01/2017

NCT01724606

  Whole Brain Radiotherapy (WBRT) With Sorafenib for Breast Cancer Brain Metastases (BCBM)
612/01/2017

NCT02971501

  Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases
611/30/2017

NCT02962167

  Modified Measles Virus (MV-NIS) for Children and Young Adults With Recurrent Medulloblastoma or Recurrent ATRT
611/30/2017

NCT02960230

  H3.3K27M Peptide Vaccine for Children With Newly Diagnosed DIPG and Other Gliomas
1111/30/2017

NCT02331498

  Phase I/II Study of Pazopanib+ Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme
111/30/2017

NCT02313272

  Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas
111/30/2017

NCT03352427

  Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring PDGFR/FGFR Alterations
111/29/2017

NCT03257631

  A Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors
1211/29/2017

NCT03086616

  CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With DIPG
111/29/2017

NCT03030066

  Study of DS-1001b in Patients With Gene IDH1-Mutated Gliomas
111/29/2017

NCT02849171

  Assessing 18F-Fluorocholine (18F-FCH) PET to Distinguish True Tumor Progression From Pseudoprogression in High-grade Gliomas
111/29/2017

NCT02639325

  Tumor Related Epilepsy
111/29/2017

NCT02571530

  Super-selective Intra-arterial Cerebral Infusion of Trastuzumab for the Treatment of Cerebral Metastases of HER2/Neu Positive Breast Cancer
111/29/2017

NCT02303678

  D2C7 for Adult Patients With Recurrent Malignant Glioma
111/29/2017

NCT01421524

  Study of CC-122 to Evaluate the Safety, Tolerability, and Effectiveness for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple Myeloma
2211/29/2017

NCT01269853

  Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA
111/29/2017

NCT01813877

  Response Monitoring Trial in Patients With Suspected Recurrence of Glioblastoma
111/28/2017



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