Clinical Trials
Braintumor Website

 For People with Newly Diagnosed Glioblastoma Multiforme
A Study of ABT-414 in Subjects With Newly Diagnosed Glioblastoma (GBM)
With Epidermal Growth Factor Receptor (EGFR) Amplification

 For People with Reccurent Glioblastoma Multiforme (and other malignant gliomas)
A Study of ABT-414 in Adult or Pediatric Subjects With Recurrent Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification
Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Glioblastoma at First Recurrence or Progression
Aldoxorubicin Trial for recurrent GBM.

These trials were the most recently added or updated

NCT Trial Name# of CentersLast Updated

NCT03233204

  Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
5704/02/2018

NCT03220035

  Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)
4104/02/2018

NCT03213665

  Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)
4404/02/2018

NCT03155620

  Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
8704/02/2018

NCT02993146

  Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases
604/02/2018

NCT01922076

  WEE1 Inhibitor AZD1775 and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
1704/02/2018

NCT01849146

  Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma
504/02/2018

NCT01604512

  A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor Progression
604/02/2018

NCT03412877

  Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in People With Metastatic Cancer
103/31/2018

NCT03190967

  T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery
103/31/2018

NCT01986348

  A Phase 2 Study Evaluating the Efficacy and Safety of Selinexor (KPT-330) in Patients With Recurrent Gliomas
103/31/2018

NCT03246113

  Tolerability of Cannabis in Patients Receiving Concurrent Chemoradiation for Glioblastoma
103/30/2018

NCT01445483

  Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain Metastases
103/30/2018

NCT03330197

  A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors or DIPG
203/29/2018

NCT03213704

  Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)
6403/29/2018

NCT02133183

  Sapanisertib Before and After Surgery in Treating Patients With Recurrent Glioblastoma
703/29/2018

NCT01089101

  Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
103/28/2018

NCT03353896

  NovoTTF-200A Device in Treating Patients With Newly Diagnosed High Risk Oligodendroglioma
103/27/2018

NCT02076152

  FMISO PET Study of Glioblastoma
103/27/2018

NCT01987830

  Bevacizumab w / Temozolomide PET & Vascular MRI For GBM
103/27/2018

NCT03466450

  Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma
303/26/2018

NCT03393000

  Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjects
603/26/2018

NCT03343197

  Study of AG-120 and AG-881 in Subjects With Low Grade Glioma
303/26/2018

NCT03174197

  Atezolizumab (aPDL1) + Temozolomide and Radiation for Newly Diagnosed Glioblastoma (GBM)
103/26/2018

NCT02974621

  Cediranib Maleate and Olaparib Compared to Bevacizumab in Treating Patients With Recurrent Glioblastoma
903/26/2018

NCT02667587

  An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
12103/26/2018

NCT02617589

  An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
6203/26/2018

NCT02359565

  Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, or Hypermutated Brain Tumors
903/26/2018

NCT02343991

  Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound
103/26/2018

NCT02085070

  MK-3475 in Melanoma and NSCLC Patients With Brain Metastases
103/26/2018

NCT01473485

  ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors
103/26/2018

NCT00147056

  MRI-Guided Focused Ultrasound Feasibility Study for Brain Tumors
103/26/2018

NCT01174121

  Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
103/24/2018

NCT03149003

  A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy
2003/23/2018

NCT02465268

  Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme
203/23/2018

NCT02455245

  A Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults With Previously Untreated Low Grade Glioma
903/23/2018

NCT02193347

  IDH1 Peptide Vaccine for Recurrent Grade II Glioma
103/22/2018

NCT02101905

  Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma
603/22/2018

NCT01851733

  MRI-Guided Laser Surgery and Doxorubicin Hydrochloride in Treating Patients With Recurrent Glioblastoma Multiforme
103/22/2018

NCT01847833

  Advanced MRI Applications Development
103/22/2018

NCT00267865

  Chemotherapy and HAART to Treat AIDS-related Primary Brain Lymphoma
103/22/2018

NCT03480867

  Pre-operative RT and TMZ in Patients With Newly Diagnosed GBM Diagnosed Glioblastoma. A Phase I Study. (PARADIGMA)
103/21/2018

NCT02974803

  Concurrent Dabrafenib and Trametinib With Sterotactic Radiation in Patients With BRAF Mutation-Positive Malignant Melanoma and Brain Metastases
403/21/2018

NCT02731521

  Clinical Development of MR Spectroscopy and Imaging in Brain Cancers
103/21/2018

NCT02095132

  WEE1 Inhibitor MK-1775 and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
1803/21/2018

NCT01326104

  Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor
303/21/2018

NCT00811148

  Florida Center for Brain Tumor Research
103/21/2018

NCT03477513

  Personalized Treatment of Glioblastoma Via Image-Guided Predictive Modeling of Recurrence: A Single-Arm, Single Institutional Pilot Prospective Study of Dose-Escalated Radiation Therapy
103/20/2018

NCT03223103

  Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma
103/20/2018

NCT02864368

  Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigens
103/20/2018



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