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04/26/17 New Tupperware Fundraiser!
This fundraiser gives us 40% of your purchases! Please remember to use this link if you buy Tupperware!
04/21/17 Pediatric Brain Tumor Mutations are Detectable in Cerebrospinal Fluid
This is a huge advance, although it is a small study and needs to be validated. The concept of a liquid biopsy is that instead of trying to get tumor tissue directly, you get it from blood, or in this case, cerebral spinal fluid, which is a lot easier than brain surgery. You can usually only get a biopsy once or twice of the actual tumor. In some cases, it is dangerous to do a biopsy at all. However, with a liquid biopsy, you can repeat it over time, and see how the tumor is responding to treatment. We are funding the development of a new drug that targets the exact marker this researcher is testing for. I can envision a day when you do this test, and personalize treatment based on it. Then repeat to see how the tumor is trying to mutate around the drug and be able to change the treatment plan.
04/19/17 Cloud Over Pediatric Oncologist and Brain Cancer Vaccine
This is a dificult article to interpret. I have met this doctor and we went over his research in detail. The results he showed me were pretty good - but nowhere near claiming to be a cure. It was in line with the vaccine trials here in the USA. Some people do very well - others aren't helped at all. I know of a few people doing well on his vaccine. I also know people who weren't heped by it. We recently started tracking his treatment in our virtual trial project but don't have enough data to make a judegement on it yet.
04/14/17 Long-term Survival in Glioblastoma with Cytomegalovirus pp65-Targeted Vaccination
This small study had amazing results. Compared to matched historical controls, median progression free survival was 25.3 months in the vaccine group vs. 8.0 months in the historical control group and median overall survival was 41.1 vs. 19.2 months. Only 1 patient had significant side effects, an allergic reaction to the immune stimulant they used - which was discontinued and she was able to continue on the vaccine.
Disclaimer: I (Al Musella, DPM) am on the patient advisory board at The Preston Robert Tisch Brain Tumor Center.
04/09/17 DFFN: Phase 3 Trial of TSC in GBM to Initiate in 2017
Results from earlier studies were impressive with " In the subgroup of patients considered inoperable, the chance of survival at two years for those who received TSC was increased by over 100 percent, as 40 percent in the TSC group were alive at two years compared to less than 20 percent in the control. "
Displaying Stories 1 to 20 of 6151