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Search Term: Surgery

NCT Trial Name# of Centers

NCT02239120

  Dabigatran Etexilate for Secondary Stroke Prevention in Patients With Embolic Stroke of Undetermined Source (RE-SPECT ESUS)
449

NCT02523014

  A Study Looking at Targeted Therapy According to Tumor Markers for People With Meningiomas
340

NCT01471522

  International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)
314

NCT01814813

  Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery
286

NCT02152982

  Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
273

NCT01648348

  Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma Multiforme
242

NCT01781468

  Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma
240

NCT02834013

  Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
224

NCT00991029

  Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial
210

NCT00869401

  Dasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
207

NCT01480479

  Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma
206

NCT02100696

  A Study of the Efficacy and Safety of Etrolizumab in Ulcerative Colitis Participants Who Are Refractory to or Intolerant of Tumor Necrosis Factor (TNF) Inhibitors
205

NCT02490878

  Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases
203

NCT02360215

  Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases
187

NCT00085735

  Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma
184

NCT02388165

  Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation
179

NCT01609790

  Bevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain Tumors
175

NCT01231906

  Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
171

NCT00978458

  Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma
168

NCT00919750

  Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
160

NCT00887146

  Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma
156

NCT02724579

  Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma
152

NCT01096368

  Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma
150

NCT01085630

  Pemetrexed Disodium/Observation in Treating Patients W/ Malignant Pleural Mesothelioma w/Out Progressive Disease After 1st Line Chemotherapy
145

NCT00082745

  Study of Late-Occurring Complications in Childhood Cancer Survivors
144

NCT02179086

  Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
142

NCT01649089

  Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer
135

NCT00336024

  Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma
131

NCT02568267

  Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
129

NCT00329719

  Sorafenib and Temsirolimus in Treating Patients With Recurrent Glioblastoma
121

NCT03155620

  Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
113

NCT03281954

  Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed After Surgery by Atezolizumab or Placebo
106

NCT00020566

  Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing's Sarcoma
104

NCT00653068

  Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System
87

NCT00916409

  Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM)
86

NCT01602666

  Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors
85

NCT02831959

  Effect of TTFields (150 kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-10 Brain Metastases Following Radiosurgery (METIS)
85

NCT03180268

  Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery
83

NCT03233204

  Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
83

NCT01713946

  A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures
81

NCT01390948

  A Study of Avastin (Bevacizumab) in Combination With Temolozomide (TMZ) and Radiotherapy in Paediatric and Adolescent Patients With High-Grade Glioma
78

NCT00895622

  Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma
74

NCT01835236

  Trastuzumab & Pertuzumab Followed by T-DM1 in MBC
74

NCT01564056

  Adjuvant Systemic Treatment for (ER)-Positive HER2-negative Breast Carcinoma in Women Over 70 According to Genomic Grade (GG): Chemotherapy + Endocrine Treatment Versus Endocrine Treatment
72

NCT00045968

  Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer
70

NCT02066220

  International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma
68

NCT02915744

  A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine
66

NCT00389181

  A Randomized Trial of Unruptured Brain AVMs
66

NCT02017964

  Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-Metastatic Desmoplastic Medulloblastoma
65

NCT02546102

  Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma
64

NCT02414165

  The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma
63

NCT02667587

  An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
62

NCT02573324

  A Study of ABT-414 in Subjects With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification ( Intellance1 )
59

NCT01381718

  Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor
59

NCT03269175

  BENEFIT 15 Long-term Follow-up Study of the BENEFIT and BENEFIT Follow-up Studies
59

NCT02310269

  Long Term Safety and Efficacy of Pasireotide s.c. in Patients With Cushing's Disease
55

NCT02511405

  A Phase 3, Pivotal Trial of VB-111 Plus Bevacizumab vs. Bevacizumab in Patients With Recurrent Glioblastoma (GLOBE)
53

NCT02369653

  Safety and Efficacy Study of Apixaban to Prevent Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With PEG Asparaginase
52

NCT03149003

  A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy
49

NCT02234050

  Trabectedin for Recurrent Grade II/III Meningioma
47

NCT01441596

  Lux-Breast 3; Afatinib Alone or in Combination With Vinorelbine in Patients With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer Suffering From Brain Metastases
47

NCT02034110

  Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers
45

NCT00898755

  Collecting and Storing Tissue From Young Patients With Cancer
44

NCT01498328

  A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma
43

NCT02601209

  Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma
42

NCT02162537

  Therapeutic Strategies in Patients With Non-squamous Non-small Cell Lung Cancer With Brain Metastases
39

NCT01372774

  Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery
37

NCT01062399

  Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
36

NCT02320058

  An Investigational Immuno-therapy Study to Evaluate Safety and Effectiveness in Patients With Melanoma That Has Spread to the Brain, Treated With Nivolumab in Combination With Ipilimumab, Followed by Nivolumab by Itself
35

NCT01417507

  Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone Surgery
35

NCT01412424

  Efficacy and Safety of Octreolin for Acromegaly
34

NCT02180217

  Safety and Efficacy of LCI699 for the Treatment of Patients With Cushing's Disease
33

NCT02258919

  Decompressive Hemicraniectomy in Intracerebral Hemorrhage
32

NCT01730950

  Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma
31

NCT01164189

  Bevacizumab in Recurrent Grade II and III Glioma
28

NCT02265770

  An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma
28

NCT01982942

  Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis
28

NCT01716117

  Safety and Effectiveness of an Intracranial Aneurysm Embolization System for Treating Large or Giant Wide Neck Aneurysms
27

NCT02416492

  A Study of Modified Stem Cells in Traumatic Brain Injury (TBI)
25

NCT01677741

  A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects
24

NCT02034708

  Efficacy Evaluation of Dotarem®-Enhanced MRI Compared to Gadovist®/Gadavist®-Enhanced MRI in the Diagnosis of Brain Tumors
23

NCT01182350

  Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)
23

NCT03243461

  International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)
23

NCT03257631

  A Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors
22

NCT01632228

  A Study of Onartuzumab (MetMAb) in Combination With Bevacizumab Compared to Bevacizumab Alone or Onartuzumab Monotherapy in Patients With Recurrent Glioblastoma
22

NCT02357147

  Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM).
22

NCT02168764

  Sphenopalatine Ganglion Stimulation for the Treatment of Chronic Cluster Headache
22

NCT01878617

  A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
21

NCT01503827

  Whole Brain Radiotherapy Following Local Treatment of Intracranial Metastases of Melanoma
21

NCT02761070

  Bevacizumab Alone Versus Dose-dense Temozolomide Followed by Bevacizumab for Recurrent Glioblastoma, Phase III
21

NCT02323880

  Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas
21

NCT01421524

  Study of CC-122 to Evaluate the Safety, Tolerability, and Effectiveness for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple Myeloma
21

NCT01582061

  An Open-label, Multi-center, Expanded Access Study of Pasireotide s.c. in Patients With Cushing's Disease
21

NCT03148457

  Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial
20

NCT02571036

  A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies
19

NCT02997423

  Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM)
19

NCT02684838

  Vigilant ObservatIon of GlIadeL WAfer ImplaNT Registry
19

NCT02650401

  Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
19

NCT01303497

  Efficacity of Weekly Paclitaxel in Association or Not With Bevacizumab in Metastatic or Locally Advanced Angiosarcomas
19

NCT00482677

  Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme
19

NCT01442662

  Efficacy of Gemcitabine With Pazopanib as Second Line Treatment in Patients With Metastatic or Relapsed Uterine or Soft Tissue Leiomyosarcomas
19

NCT02891070

  Efficacy and Safety of FS VH S/D 500 S-apr as an Adjunct to Sutured Dural Repair in Cranial Surgery
19

NCT01922076

  WEE1 Inhibitor AZD1775 and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
18

NCT02300766

  Cerebellar Mutism Syndrome Study
18

NCT02004691

  Efficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency
18

NCT00517751

  Condition of Approval Study
18

NCT02162732

  Molecular-Guided Therapy for Childhood Cancer
17

NCT01748149

  Vemurafenib in Children With Recurrent/Refractory BRAFV600E-mutant Gliomas
17

NCT01324479

  Study of INC280 in Patients With c-MET Dependent Advanced Solid Tumors
17

NCT01356290

  Metronomic and Targeted Anti-angiogenesis Therapy for Children With Recurrent/Progressive Medulloblastoma
17

NCT01026493

  Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma
17

NCT01597414

  Elderly Metastatic Breast Cancer: Pertuzumab-Herceptin vs Pertuzumab-Herceptin-Metronomic Chemotherapy, Followed by T-DM1
17

NCT01576666

  Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors
17

NCT02073565

  HARMONEE - Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt
17

NCT02078648

  Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme
16

NCT02124772

  Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations
16

NCT03115333

  DSC-MRI in Measuring Relative Cerebral Blood Volume for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma
16

NCT01934361

  Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme
16

NCT02697734

  Efficacy and Safety Evaluation of Osilodrostat in Cushing's Disease
16

NCT02585713

  Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism
16

NCT01602588

  A Randomised Trial Investigating the Additional Benefit of Hydroxychloroquine(HCQ)to Short Course Radiotherapy (SCRT) in Patients Aged 70 Years and Older With High Grade Gliomas (HGG)
15

NCT01358084

  Phase II Study of NGR-hTNF Versus Placebo as Maintenance Treatment in Patients With Advanced Malignant Pleural Mesothelioma
15

NCT00858039

  Cardiotoxicity of Adjuvant Trastuzumab
15

NCT00626990

  Radiation Therapy With or Without Temozolomide in Treating Patients With Anaplastic Glioma
14

NCT00867178

  Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System
14

NCT02632370

  5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Malignant Tumor
14

NCT02343406

  Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas (INTELLANCE 2)
14

NCT03018288

  Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)
14

NCT02960230

  H3.3K27M Peptide Vaccine for Children With Newly Diagnosed DIPG and Other Gliomas
14

NCT01204333

  Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis
14

NCT01288560

  IMAGE-HF Project I-A: Cardiac Imaging in Ischemic Heart Failure (AIMI-HF)
14

NCT03215511

  Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers
14

NCT00987688

  The Prophylactic Hypothermia Trial to Lessen Traumatic Brain Injury
14

NCT03150862

  A Study Assessing BGB-290 With Radiation and/or Temozolomide (TMZ) in Subjects With Newly Diagnosed or Recurrent Glioblastoma
13

NCT02379572

  Impact of iMRI on the Extent of Resection in Patients With Newly Diagnosed Glioblastomas
13

NCT02212574

  Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma
13

NCT00276640

  Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade Gliomas
13

NCT01089101

  Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
13

NCT01450449

  Short Course vs. Standard Course Radiotherapy in Elderly and/or Frail Patients With Glioblastoma Multiforme
13

NCT03393000

  Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjects
13

NCT01949948

  Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic Stroke
13

NCT03184090

  Molecular Mechanisms of Resistance and Sensitivity to Palbociclib Re-challenge in ER+ mBC
13

NCT01520870

  Safety and Efficacy of PF-299804 (Dacomitinib), a Pan-HER Irreversible Inhibitor, in Patients With Recurrent Glioblastoma With EGFR Amplification or Presence of EGFRvIII Mutation. A Phase II CT.
12

NCT01158651

  Study of RAD001 (Everolimus) for Children With NF1 and Chemotherapy-Refractory Radiographic Progressive Low Grade Gliomas
12

NCT01507506

  Phase III Study Comparing 2 Brain Conformational Radiotherapy in Combination With Chemotherapy in the Treatment of Glioblastoma
12

NCT02209948

  Temozolomide 12 Cycles Versus 6 Cycles of Standard First-line Treatment in Patients With Glioblastoma.
12

NCT01631552

  Phase I/II Study of IMMU-132 in Patients With Epithelial Cancers
12

NCT02285439

  Phase I/II Study of MEK162 for Children With Ras/Raf Pathway Activated Tumors
12

NCT02537600

  Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasis
12

NCT01822522

  Cabozantinib-S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency Virus
12

NCT02135926

  Comparison of Thrombectomy and Standard Care for Ischemic Stroke in Patients Ineligibility for Tissue Plasminogen Activator Treatment
12

NCT02395016

  A Study of Nimotuzumab Combinated With Gemcitabine in K-RAS Wild-type Locally Advanced and Metastatic Pancreatic Cancer
12

NCT03044834

  Review of the Paediatric Pleuropulmonary Blastoma French Series
12

NCT03389802

  Phase I Study of APX005M in Pediatric CNS Tumors
12

NCT03212274

  Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations
12

NCT01218529

  Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors
12

NCT02073994

  Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 Mutation
11

NCT02047214

  Safety & Efficacy Study of TPI 287 + Avastin in Adults With Glioblastoma That Progressed Following Prior Avastin Therapy
11

NCT01514201

  Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas
11

NCT01494662

  HKI-272 for HER2-Positive Breast Cancer and Brain Metastases
11

NCT01220271

  A Study Combining LY2157299 With Temozolomide-based Radiochemotherapy in Patients With Newly Diagnosed Malignant Glioma
11

NCT01012609

  External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade Astrocytomas
11

NCT01125800

  A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB
11

NCT02743078

  Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastoma
11

NCT02205047

  Neoadjuvant Study Using Trastuzumab or Trastuzumab With Pertuzumab in Gastric or Gastroesophageal Junction Adenocarcinoma
11

NCT02091999

  A Study of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects With Metastatic Urothelial Cancer and Other Malignant Solid Tumors That Express Nectin-4
11

NCT02844439

  Study of Tesevatinib Monotherapy in Patients With Recurrent Glioblastoma
10

NCT01756729

  Post-approval Study of NovoTTF-100A in Recurrent GBM Patients
10

NCT01156584

  A Study of a Retroviral Replicating Vector Administered to Subjects With Recurrent Malignant Glioma
10

NCT01836549

  Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors
10

NCT02273739

  Study of Orally Administered AG-221 in Subjects With Advanced Solid Tumors, Including Glioma, and With Angioimmunoblastic T-cell Lymphoma, With an IDH2 Mutation
10

NCT02357498

  Transsphenoidal Extent of Resection Study
10

NCT02616393

  Study of Tesevatinib in Subjects With Non-Small Cell Lung Cancer, EGFR Activating Mutation, Prior Treatment With a Tyrosine Kinase Inhibitor, and Brain Metastases or Leptomeningeal Metastases
10

NCT02748135

  A Two-Part Study of TB-403 in Pediatric Subjects With Relapsed or Refractory Medulloblastoma
10

NCT02658981

  Anti-LAG-3 or Urelumab Alone and in Combination With Nivolumab in Treating Patients With Recurrent Glioblastoma
10

NCT02311920

  Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma
10

NCT02423343

  A Study of Galunisertib (LY2157299) in Combination With Nivolumab in Advanced Refractory Solid Tumors and in Recurrent or Refractory NSCLC, Hepatocellular Carcinoma, or Glioblastoma
10

NCT02746081

  Phase I Study of BAY 1436032 in Patients With IDH1-mutant Solid Tumors
10

NCT01386580

  An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma.
10

NCT00796978

  Trastuzumab in Treating Older Women With Early-Stage Breast Cancer
10

NCT03080883

  Apixaban in Preventing Secondary Cancer Related Blood Clots in Cancer Patients Who Have Completed Anticoagulation Therapy
10

NCT02481154

  Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation
9

NCT02455245

  A Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults With Previously Untreated Low Grade Glioma
9

NCT02296580

  A Feasibility Study of the Nativis Voyager® System in Patients With Recurrent Glioblastoma Multiforme (GBM)
9

NCT01898273

  Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastoma
9

NCT02013297

  Study of SBRT Efficacy on Intra and Extra -Cranial Tumors or Metastasis in Pediatrics Population (SBRT Pediatrics)
9

NCT01587144

  Safety and Efficacy Study of Lucanthone When Used in Combination With Temozolomide(TMZ) and Radiation to Treat Glioblastoma Multiforme(GBM)
9

NCT01790503

  A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed Glioblastoma
9

NCT01449461

  A Phase 1/2 Study of the Oral ALK/EGFR Inhibitor AP26113
9

NCT02858895

  Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma
9

NCT03033992

  Feasibility Trial of Optune for Children With Recurrent or Progressive Supratentorial High-Grade Glioma and Ependymoma
9

NCT02974621

  Cediranib Maleate and Olaparib Compared to Bevacizumab in Treating Patients With Recurrent Glioblastoma
9

NCT02866747

  A Study Evaluating the Association of Hypofractionated Stereotactic Radiation Therapy and Durvalumab for Patients With Recurrent Glioblastoma
9

NCT01282437

  Prophylactic Cranial Irradiation (PCI) vs Observation in Stage III NSCLC
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NCT01446744

  Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastatic Tumors (SABR-COMET)
9

NCT01454102

  Study of Nivolumab (BMS-936558) in Combination With Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in Subjects With Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC) (CheckMate 012)
9

NCT02498665

  A Study of DSP-7888 Dosing Emulsion in Adult Patients With Advanced Malignancies
9

NCT01997684

  Colonic Stenting With Elective Surgery Versus Emergency Surgery in the Management of Acute Malignant Colonic Obstruction
9

NCT03373370

  Early Diagnosis of TTR Amyloidosis by Use of Molecular Biology
9

NCT02962167

  Modified Measles Virus (MV-NIS) for Children and Young Adults With Recurrent Medulloblastoma or Recurrent ATRT
8

NCT02589522

  VX-970 and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors
8

NCT01137682

  Efficacy and Safety of Pasireotide Long Acting Release (LAR) Versus Octreotide LAR or Lanreotide Autogel (ATG) in Patients With Inadequately Controlled Acromegaly
8

NCT01283542

  Evaluate the Efficacy and Safety of Pasireotide LAR on the Treatment of Patients With Clinically Non-Functioning Pituitary Adenoma.
8

NCT02336165

  Phase 2 Study of MEDI4736 in Patients With Glioblastoma
8

NCT01964300

  Peginterferon Alfa-2b in Treating Younger Patients With Craniopharyngioma That is Recurrent or Cannot Be Removed By Surgery
8

NCT02685605

  Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme
8

NCT02331719

  Evaluation of Minimally Invasive Subcortical Parafascicular Access for Clot Evacuation
8

NCT02220114

  Acceptability Study of a New Paediatric Form of Vigabatrin in Infants and Children With Infantile Spasms or Pharmacoresistant Partial Epilepsy
8

NCT02677545

  Ticagrelor Versus Clopidogrel in Carotid Artery Stenting
8

NCT03107780

  MDM2 Inhibitor AMG-232 in Treating Patients With Recurrent or Newly Diagnosed Glioblastoma
8

NCT03216499

  HIF-2 Alpha Inhibitor PT2385 in Treating Patients With Recurrent Glioblastoma
8

NCT02725684

  Using Genomic Analysis to Guide Individual Treatment in Glioblastoma
7

NCT02650752

  Intermittent High-Dose Lapatinib in Tandem With Capecitabine for HER2 Overexpressed/Amplified Metastatic Breast Cancer With Central Nervous System (CNS) Metastases
7

NCT02429570

  Meclofenamate in Subjects With Recurrent or Progressive Brain Metastasis From Solid Tumor Primary
7

NCT02395692

  Methoxyamine and Temozolomide in Treating Patients With Recurrent Glioblastoma
7

NCT02530320

  Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Patients With Oligodendroglioma or Recurrent Oligoastrocytoma Anaplastic With the Activity of the Protein RB Preserved
7

NCT01812616

  A Safety Study of Sativex Compared With Placebo (Both With Dose-intense Temozolomide) in Recurrent Glioblastoma Patients
7

NCT02185352

  Bevacizumab, Etoposide and Cisplatin Followed by Whole Brain Radiotherapy in Breast Cancer With Brain Metastases
7

NCT02133183

  Sapanisertib Before and After Surgery in Treating Patients With Recurrent Glioblastoma
7

NCT02101905

  Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma
7

NCT01933815

  Dose-Escalation Study of TPI 287 + Avastin Followed by Randomized Study of the Same Versus Avastin for Glioblastoma
7

NCT02034799

  Phase IV Bioseal Study in Meningioma Surgery
7

NCT01310868

  Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastoma
7

NCT01339052

  Phase II Study of BKM120 for Subjects With Recurrent Glioblastoma
7

NCT01390571

  Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma
7

NCT01755624

  Effect of NovoTTF-100A in Non-small Cell Lung Cancer (NSCLC) Patients With 1-5 Brain Metastases Following Optimal Standard Local Treatment (COMET)
7

NCT01892397

  Pilot Study of Optune (NovoTTF-100A) for Recurrent Atypical and Anaplastic Meningioma
7

NCT02903069

  Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer
7

NCT02977780

  INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
7

NCT02981940

  A Study of Abemaciclib in Recurrent Glioblastoma
7

NCT03276286

  Nativis Voyager for Newly Diagnosed GBM
7

NCT01222221

  Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
7

NCT00512109

  Vascular Events In Noncardiac Surgery Patients Cohort Evaluation Study (VISION)
7

NCT01151631

  Occipital Nerve Stimulation in Medically Intractable Chronic Cluster Headache
7

NCT02058056

  Early Hippocampal Avoidance Prophylactic Cranial Irradiation in Patients With LD SCLC
7

NCT01763606

  Enoxaparin Versus Aspirin in Patients With Cancer and Stroke
7

NCT02601950

  A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma
7

NCT03186638

  Exercise and Low-Dose Ibuprofen for Cognitive Impairment in Colorectal Cancer Patients Receiving Chemotherapy
7

NCT03058289

  A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6
6

NCT02852655

  A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma
6

NCT02926222

  Regorafenib in Relapsed Glioblastoma
6

NCT01724606

  Whole Brain Radiotherapy (WBRT) With Sorafenib for Breast Cancer Brain Metastases (BCBM)
6

NCT01621906

  18F-FLT-PET Imaging of the Brain in Patients With Metastatic Breast Cancer to the Brain Treated With Whole Brain Radiation Therapy With or Without Sorafenib: Comparison With MR Imaging of the Brain
6

NCT01470794

  Study of a Retroviral Replicating Vector to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor
6

NCT01349036

  A Phase 2 Study of PLX3397 in Patients With Recurrent Glioblastoma
6

NCT01222754

  Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
6

NCT01226940

  Lenalidomide and Radiation Therapy in Treating Young Patients With Pontine Glioma or High-Grade Glioma
6

NCT00392327

  Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma
6

NCT00602667

  Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma
6

NCT00826241

  Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma
6

NCT02149225

  GAPVAC Phase I Trial in Newly Diagnosed Glioblastoma Patients
6

NCT02498951

  Obinutuzumab in Treating Patients With Central Nervous System Lymphoma Who Have Achieved a Complete Response
6

NCT02026271

  A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma
6

NCT02750891

  A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas
6

NCT02540356

  Phase 1/2a Two-Arm Dose-Escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer
6

NCT02535312

  Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Cisplatin and Pemetrexed
6

NCT02509156

  Stem Cell Injection in Cancer Survivors
6

NCT02397928

  Safety and Efficacy of TTFields Concomitant With Pemetrexed and Cisplatin or Carboplatin in Malignant Pleural Mesothelioma
6

NCT01607905

  Safety Study of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients With Advanced or Metastatic Solid Tumor Cancer
6

NCT02192333

  Survivorship Care in Reducing Symptoms in Young Adult Cancer Survivors
6

NCT00419432

  Outcomes of Orthopaedic Surgery Using Gait Laboratory Versus Observational Gait Analysis in Children With Cerebral Palsy
6

NCT01473095

  Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma
6

NCT03343197

  Study of AG-120 and AG-881 in Subjects With Low Grade Glioma
6

NCT03245151

  Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors
6

NCT03054363

  Tucatinib, Palbociclib and Letrozole in Metastatic Hormone Receptor Positive and HER2-positive Breast Cancer
6

NCT03449381

  This Study Aims to Find the Best Dose of BI 907828 in Patients With Different Types of Advanced Cancer (Solid Tumors)
6

NCT03423628

  A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
6

NCT02765165

  Phase 1/2 Study of USL311 Alone and in Combination With Lomustine in Subjects With Advanced Solid Tumors and Relapsed/Recurrent Glioblastoma Multiforme (GBM)
5

NCT02455557

  SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
5

NCT02394626

  Surgery for Recurrent Glioblastoma
5

NCT02386826

  INC280 Combined With Bevacizumab in Patients With Glioblastoma Multiforme
5

NCT02115074

  Safety of Fluvastatin-Celebrex Association in Low-grade and High Grade Optico-chiasmatic Gliomas
5

NCT02330562

  Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab
5

NCT01989884

  An Efficacy Study Of Ortataxel In Recurrent Glioblastoma
5

NCT00879437

  Valproic Acid and Radiation Followed by Maintenance Valproic Acid and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma
5

NCT01478178

  Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma
5

NCT01621542

  Clinical Study of WT2725 in Patients With Advanced Malignancies
5

NCT01106508

  A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors
5

NCT00859222

  LBH589 and Bevacizumab in Patients With Recurrent High Grade Glioma
5

NCT01305122

  Tumor and Treatments Impact on Neurocognitive Functions and Quality of Life of Patients With OMS Grade II Glioma
5

NCT01849146

  Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma
5

NCT01478321

  Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas
5

NCT02353000

  Whole Brain Radiotherapy (WBRT) Versus Stereotactic Radiosurgery (SRS) for 4 Upto 10 Brain Metastases
5

NCT00394628

  AQ4N in Combination With Radiotherapy and Temozolomide in Subjects With Newly Diagnosed Glioblastoma Multiforme
5

NCT03149575

  VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM
5

NCT02423863

  In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol®
5

NCT03206021

  Treatment of Children With Recurrent Refractory Brain/Solid Tumors and Recurrent Ependymoma
5

NCT01443078

  Neoadjuvant Platinum-based Chemotherapy for Patients With Resectable , Non-small Cell Lung Cancer With Switch to Chemotherapy Alternative in Nonresponders (NEOSCAN)
5

NCT00904735

  Hydroxyurea With or Without Imatinib Mesylate in Treating Patients With Recurrent or Progressive Meningioma
5

NCT01014767

  Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors
5

NCT02219269

  A Complex Contraception Registry
5

NCT01675765

  Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma
5

NCT01638533

  Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction
5

NCT01858168

  Phase I Study of Olaprib and Temozolomide for Ewings Sarcoma
5

NCT02469922

  Positron Emission Tomography (PET) During Radio-chemotherapy to Treat Otorhinolaryngological Cancer
5

NCT02619864

  mTORC1/mTORC2 Kinase Inhibitor AZD2014 in Previously Treated Glioblastoma Multiforme
4

NCT02968940

  Avelumab With Hypofractionated Radiation Therapy in Adults With Isocitrate Dehydrogenase (IDH) Mutant Glioblastoma
4

NCT02909777

  Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphoma
4

NCT02859857

  Phase 1 Study of BXQ-350 in Adult Patients With Advanced Solid Tumors
4

NCT02768389

  Feasibility Trial of the Modified Atkins Diet and Bevacizumab for Recurrent Glioblastoma
4

NCT01564914

  A Phase 2 Evaluation of TRC105 In Combination With Bevacizumab for the Treatment Of Recurrent or Progressive Glioblastoma That Has Progressed on Bevacizumab
4

NCT00902577

  MRI and PET Scan Using 18F-Fluoromisonidazole In Assessing Tumor Hypoxia in Patients With Newly Diagnosed Glioblastoma Multiforme
4

NCT01107522

  Safety and Tolerability of Carboxyamidotriazole Orotate (CTO) in Solid Tumors or With Temodar® in Glioblastoma or Other Recurrent Malignant Gliomas or in Combination With Temodar® and Radiation Therapy for Patients With Newly Diagnosed Glioblastoma and Malignant Gliomas
4

NCT01518413

  Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid Tumors
4

NCT01257594

  EGFR Inhibition Using High Dose Administration of Erlotinib Weekly for Recurrent Malignant Gliomas With EGFR Variant III Mutation
4

NCT01112527

  PF-00299804 in Adult Patients With Relapsed/Recurrent Glioblastoma
4

NCT01985256

  Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor
4

NCT02014844

  Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With Glioblastoma
4

NCT02336451

  A Phase II Study to Evaluate the Efficacy and Safety of Oral Ceritinib in Patients With ALK-positive NSCLC Metastatic to the Brain and/or to Leptomeninges
4

NCT02296476

  A Trial With Dose Optimization of OTX015 in Recurrent Glioblastoma Multiforme (GBM) Patients
4

NCT02155920

  Everolimus for Children With Recurrent or Progressive Ependymoma
4

NCT02374242

  Anti?PD 1 Brain Collaboration for Patients With Melanoma Brain Metastases
4

NCT02460068

  A Study of Fotemustine(FTM) Vs FTM and Ipilimumab (IPI) or IPI and Nivolumab in Melanoma Brain Metastasis
4

NCT02459886

  Single-Ascending Dose Study of BIIB054 in Healthy Participants
4

NCT02996084

  MS PATHS Normative Sub-Study
4

NCT02928692

  Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium
4

NCT01905228

  A Phase 1 Trial of CBL0137 in Patients With Metastatic or Unresectable Advanced Solid Neoplasm
4

NCT00576654

  Veliparib and Irinotecan Hydrochloride in Treating Patients With Cancer That Is Metastatic or Cannot Be Removed by Surgery
4

NCT03561896

  Hypofractionated Brain Radiationcavity
4

NCT01290809

  Prophylactic Cranial Irradiation (PCI) Cognitive Tests in Non-small Cell Lung Cancer (NSCLC) Patients
4

NCT01139892

  The Canadian UnRuptured Endovascular Versus Surgery Trial (CURES)
4

NCT01332929

  Safety Evaluation of a Combination of Brain Radiation Therapy and Bevacizumab (Avastin®) for Treatment of Brain Metastasis
4

NCT01362803

  AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors
4

NCT01371201

  First International Randomized Study in Malignant Progressive Pheochromocytoma and Paraganglioma
4

NCT03296696

  Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma
4

NCT03416530

  ONC201 in Pediatric H3 K27M Gliomas
4

NCT03466450

  Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma
4

NCT03355794

  A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)
4

NCT03297346

  Early Detection of Cardiovascular Changes After Radiotherapy for Breast Cancer
4

NCT02282917

  Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma
3

NCT02430727

  The Safety and Efficacy Study of Afatinib (CT) Compared With Afatinib (GIOTRIF) in Patients With Solid Tumors (Including Mutations Identified EGFR)
3

NCT02525692

  Oral ONC201 in Adult Recurrent Glioblastoma and H3 K27M-mutant Glioma
3

NCT02465268

  Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme
3

NCT02576665

  A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)
3

NCT02704858

  Safety and Efficacy Study in Recurrent Grade IV Glioma
3

NCT02270034

  Study to Evaluate Safety and Activity of Crizotinib With Temozolomide and Radiotherapy in Newly Diagnosed Glioblastoma
3

NCT02288962

  Dopamine Agonist Treatment of Non-functioning Pituitary Adenomas
3

NCT02038218

  Study of 4-Demethyl-4-cholesteryloxycarbonylpenclome in Patients With Brain Tumors
3

NCT00916630

  Treatment of Recurrent Primary or Secondary Central Nervous System (CNS) Lymphoma With ALIMTA (Pemetrexed)
3

NCT00275067

  Arsenic Trioxide, Temozolomide, and Radiation Therapy in Treating Patients With Malignant Glioma That Has Been Removed By Surgery
3

NCT01189266

  Vorinostat and Radiation Therapy Followed By Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Pontine Glioma
3

NCT01326104

  Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor
3

NCT01295944

  Carboplatin and Bevacizumab for Recurrent Ependymoma
3

NCT01551680

  A Trial Evaluating Concurrent Whole Brain Radiotherapy and Iniparib in Multiple Non Operable Brain Metastases
3

NCT01445691

  More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery
3

NCT01380782

  BIBF 1120 for Recurrent High-Grade Gliomas
3

NCT01138033

  Study of a Focal Adhesion Kinase Inhibitor in Subjects With Solid Tumors
3

NCT01149850

  Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma
3

NCT01466686

  Low Dose Radiation Therapy for Glioblastoma Multiforme
3

NCT01391143

  Safety Study of MGA271 in Refractory Cancer
3

NCT01617733

  Pasireotide Therapy in Patients With Nelson's Syndrome
3

NCT01525459

  Gene Expression, Immunological Status and Metabolome in Glioma Patients
3

NCT01189240

  R04929097 and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma
3

NCT01236560

  Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma
3

NCT00551122

  Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors
3

NCT01670890

  Efficacy and Safety of TMZ Plus CDDP in the Patients With Recurrent Malignant Gliomas
3

NCT01812603

  A Safety Study of Sativex in Combination With Dose-intense Temozolomide in Patients With Recurrent Glioblastoma
3

NCT01898130

  Bevacizumab in Pats w/ Recurrent ST Brain Metas Who Have Failed Whole Brain Radiation Therapy
3

NCT01941602

  A Comparative Study of Prophylactic Anticoagulation in Meningioma Surgery
3

NCT02783300

  Dose Escalation Study of GSK3326595 in Subjects With Solid Tumors and Non-Hodgkin's Lymphoma
3

NCT02871843

  Phase 1 Two Part Dose Escalation Trial of RRx-001 + Radiation + Temozolomide and RRx-001 + Temozolomide Post-RT In Newly Diagnosed Glioblastoma and Anaplastic Gliomas
3

NCT02885324

  Pilot Study of Cabozantinib for Recurrent or Progressive High-Grade Glioma in Children
3

NCT03071874

  Vistusertib (AZD2014) For Recurrent Grade II-III Meningiomas
3

NCT03143322

  Standard Treatment +/- SBRT in Solid Tumors Patients With Between 1 and 3 Bone-only Metastases
3

NCT03395587

  Efficiency of Vaccination With Lysate-loaded Dendritic Cells in Patients With Newly Diagnosed Glioblastoma
3

NCT03398694

  Pre-operative Stereotactic Radiosurgery Followed by Resection for Patients With Brain Metastases
3

NCT03522298

  Safety, Pharmacokinetics and Efficacy of GDC-0084 in Newly-diagnosed Glioblastoma Multiforme
3

NCT03491683

  INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)
3

NCT03551600

  Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus
3

NCT03422679

  Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies
3

NCT03411408

  Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.
3

NCT03373487

  Cognitive Rehabilitation in Brain Tumor Patients After Neurosurgery
3

NCT03382977

  Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects
3

NCT03330197

  A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors or DIPG
3

NCT03295396

  ONC201 in Adults With Recurrent H3 K27M-mutant Glioma
3

NCT01343693

  MaxAn Post Market Surveillance Validation
3

NCT03589014

  Treat_CCM: Propranolol in Cerebral Cavernous Malformation
3

NCT03610763

  Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
3

NCT00398437

  Magnetic Resonance Imaging for the Early Detection of CNS Metastases in Women With Stage IV Breast Cancer
3

NCT01239134

  Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors
3

NCT01848652

  Phase II Study Evaluating a Combination of Pegylated Liposomal Doxorubicin and Dexamethasone for the Treatment of Immunocompetent Patients With Cerebral Lymphoma Relapsed or Refractory to First-line Chemotherapy With High Dose Methotrexate (MTXHD) and / or High-dose Cytarabine.
3

NCT02359097

  Steady State Blood Volume Maps Using Ferumoxytol Non-stoichiometric Magnetite MRI in Imaging Patients With Glioblastoma
3

NCT02318199

  Emergence Agitation in Adult Patients After Intracranial Surgery
3

NCT02292654

  Safety, Tolerability, PK, and Efficacy Evaluation of Repeat Ascending Doses of rhASM in Pediatric Patients <18 Years of Age With Acid Sphingomyelinase Deficiency
3

NCT02122185

  Metformin Hydrochloride and Combination Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
3

NCT02098005

  Pain Neuroscience Education Combined With Cognition-targeted Motor Control Training
3

NCT02946866

  The Natural History of Prospective Symptomatic Hemorrhage in Adult Patients With Cerebral Cavernous Malformation
3

NCT02384876

  Determination of the Optimal Dose of Ephedrine in Intraoperative Arterial Hypotension of Newborns and Infants up to 6 Months of Age.
3

NCT02981953

  TRI-REPAIR: TrIcuspid Regurgitation RePAIr With CaRdioband Transcatheter System
3

NCT02637674

  Uterine Allotransplantations Using Uterine Grafts From Brain-dead Female Donors
3

NCT02843035

  GZ/SAR402671 in Combination With Cerezyme in Adult Patients With Gaucher Disease Type 3
3

NCT02391324

  Effectiveness of Robotic Gait Training and Physical Therapy for Children and Youth With Cerebral Palsy
3

NCT02465099

  Posterior Spinal Fusion With Two Energy Dissection Techniques
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  Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults
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  Measure of the Potential Evoked by Electric Stimulation
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  Trial of Nivolumab With Radiation or Nivolumab and Ipilimumab With Radiation for the Treatment of Intracranial Metastases From Non-Small Cell Lung Cancer
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  Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Recurrent Glioblastoma
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  Efficacy of Cognitive and Physical Trainings in Pediatric Cancer Survivors
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  Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)
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  Enhancing Optune Therapy With Targeted Craniectomy
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NCT02901925

  A Microdose Evaluation Study of ABY-029 in Recurrent Glioma
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NCT02924038

  A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)
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  Early Stereotactic Gamma Knife Radiosurgery to Residual Tumor After Surgery of Newly Diagnosed Glioblastoma
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  The Research on 89Zr-ABT806 PET Imaging in High Grade Glioma
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  [11C]Acetate PET in Patients With Glioma
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  Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions
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  International Diffuse Intrinsic Pontine Glioma (DIPG) Registry and Repository
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  Glioblastoma: Validation and Comparison Between Primary Tumor and Its Murine Model
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NCT02861898

  Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma
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NCT02863484

  Cavernous Sinus Dissection and Bleeding in Meningiomas
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  Efficacy and Safety of G-202 in PSMA-Positive Glioblastoma
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NCT02878707

  The Neuroprotective Effects of Dexmedetomidine During Brain Surgery
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  Impact of Surgery on the Treatment of Supratentorial Malignant Gliomas in Subjects Aged 70 and Over
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NCT02850744

  Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamic Effects of PQR309 in Glioblastoma Patients
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NCT02851706

  Natural History of and Specimen Banking for People With Tumors of the Central Nervous System
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NCT02794883

  Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma
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NCT02831257

  AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas
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  Study of Crenolanib in Recurrent/Refractory Glioblastoma With PDGFRA Gene Amplification
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NCT02655536

  Bevacizumab and Erlotinib in Lung Cancer With Brain Metastases, a Phase II Trial
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NCT02896335

  Palbociclib In Progressive Brain Metastases
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  Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children With Recurrent Posterior Fossa Brain Tumors
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NCT02914067

  Cognitive Biomarkers in Pediatric Brain Tumor Patients
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  Infusion of 5-Azacytidine (5-AZA) Into the Fourth Ventricle in Children With Recurrent Posterior Fossa Ependymoma
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  TG02 Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of TG02 Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
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NCT02964416

  Single Dose Tramadol Effect on Extubation Response and Quality of Emergence Post-supratentorial Intracranial Surgery
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NCT02978261

  Study of a c-Met Inhibitor PLB1001 in Patients With PTPRZ1-MET Fusion Gene Positive Recurrent High-grade Gliomas
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NCT02992015

  Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma
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NCT02933736

  Ribociclib (LEE011) in Preoperative Glioma and Meningioma Patients
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NCT02941302

  Multimodality Imaging Combined With Multiple Targets Pathological Examination for Detecting of Biological Borders of Gliomas: a Clinical Application Study
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  Safety Study of Afatinib for Brain Cancer
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  Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery
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  IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With Glioblastoma
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  T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery
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  Improving Ultrasound Images in Brain Tumour Surgery With the Use of an Acoustic Coupling Fluid Mimicking Brain Tissue.
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  The Efficacy of APT Magnetic Resonance Imaging in Predicting the Efficacy of Bevacizumab in Recurrent Malignant Gliomas
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  Restricted Calorie Ketogenic Diet as a Treatment in Glioblastoma Multiforme
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  Dose Escalation Trial of Neoadjuvant Radiosurgery for the Treatment of Metastatic Brain Tumors
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  Image-Based Quantitative Assessment of Acute Radiation-Induced Changes in Glioma
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  Atezolizumab (aPDL1) + Temozolomide and Radiation for Newly Diagnosed Glioblastoma (GBM)
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  Study of BEvacizumab in Combination With ATezolizumab in Patients With Untreated Melanoma Brain Metastases
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  Evaluation of the Interest of Ultra-high Frequency Doppler Ultrasound (UFDU) in the Surgical Management of Patients Operated in an Awake Condition for a Cerebral Tumor
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  Expedited Laser Interstitial Thermal Therapy + Chemoradiation For Newly Diagnosed High Grade Gliomas
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  HUMC 1612: Optune NovoTTF-200A System
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  Comparative Low and High Dose of Dexmedethomidine in Pituitary Tumor Removal by Transphenoid Approach
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  Blood Brain Barrier Differences in Patients With Brain Tumors Undergoing Surgery
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  Evaluation of Circulating Tumor DNA as a Theranostic Marker in the Management of Glioblastomas.
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  Astrocytoma / Desmoplastic Gamliogliomes (DIA / DIG) - Study of the French Cohort of the Last 20 Years : Clinical, Anatomopathological, Molecular and Radiological Charactersics
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  NU-0129 in Treating Patients With Recurrent Glioblastoma or Gliosarcoma Undergoing Surgery
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  TVB- 2640 in Combination With Bevacizumab in Patients With First Relapse of High Grade Astrocytoma
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  INtraoperative photoDYnamic Therapy of GliOblastoma
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  Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression
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  The Perioperative Anesthetic Management and the Prognosis of Patients Undergoing Brain Malignant Glioma Resection
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NCT02843230

  Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRI
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NCT02848794

  Apatinib and Irinotecan in Treating Patients With Recurrent High-grade Glioma
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NCT02869243

  A Dose Escalation Phase I Study Of Human- Recombinant Bone Morphogenetic Protein 4 Administrated Via CED In GBM Patients
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  [18F]Dabrafenib Molecular Imaging in Melanoma Brain Metastasis
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  A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme
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  A Phase II Study of NovoTTF-200A Alone and With Temozolomide in Patients With Low-Grade Gliomas
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  Mechanical Ventilation in Severe Brain Injury: The Effect of Positive End Expiratory Pressure on Intracranial Pressure
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  Integrin Alpha-v-Beta and [18F]-R01-MG-F2 PET/CT in Measuring Response in Patients With Pancreatic Cancer and Healthy Volunteers
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  BrUOG 329 GBM Onyvide With TMZ
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  Metabolomic Phenotyping After Surgery for Colon Cancer: Study of Novel Predictive Biomarkers
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  Effects of Riluzole on CNS Glutamate and Fatigue in Breast Cancer Survivors With High Inflammation
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  Cavity Boost Radiation Therapy vs. Observation in Cerebral Metastases After Complete Surgical Resection
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  A Study of Lorlatinib in Advanced ALK and ROS1 Rearranged Lung Cancer With CNS Metastasis in the Absence of Measurable Extracranial Lesions
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  Ipilimumab and Nivolumab in Leptomeningeal Metastases From Melanoma
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NCT02956798

  SAbR With Oligometastatic Renal Cell Carcinoma
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  One Staged Hybrid Approach of Surgical/Catheter Ablation for Persistent Atrial Fibrillation
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  Study Using Genomic, Histologic and Radiomic Analysis to Evaluate Regional Tumor Heterogeneity in Patients Undergoing Surgery for Newly Diagnosed Glioblastoma
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NCT03213561

  Stable and Independent Communication Brain-computer Interfaces
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  Japanese OMI Treatment With Kit-positive Cells for Enhanced Regeneration
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  Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.
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  A Study of Neoadjuvant Stereotactic Radiosurgery for Large Brain Metastases
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NCT03386357

  Radiotherapy With Pembrolizumab in Metastatic HNSCC
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NCT03389230

  Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma
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NCT03158389

  NCT Neuro Master Match - N²M² (NOA-20)
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  Combined Cortical/Subcortical Recording and Stimulation as a Circuit-Oriented Treatment for Obsessive-Compulsive Disorder
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  Pilot Study of Pre-Ischemic Conditioning for Intracranial Atherosclerosis
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NCT03261310

  Use of IV Acetaminophen in the Treatment of Post Operative Pain in Patients Undergoing Craniotomy and Spine Surgery
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NCT03278210

  National Study on the Interest of EEG-fMRI in the Presurgical Evaluation of Partial Epilepsies Drug
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NCT03279367

  Optimisation of Hearing Aid Fitting
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  Acupuncture Treatment for Chronic Sciatica: the Neuroimaging Pain-network Study
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NCT03425292

  A Longitudinal Assessment of Tumor Evolution in Patients With Brain Cancer
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NCT03435952

  Pembrolizumab With Intratumoral Injection of Clostridium Novyi-NT
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NCT03400917

  Autologous Dendritic Cells Loaded With Autologous Tumor Associated Antigens for Treatment of Newly Diagnosed Glioblastoma
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NCT03417297

  A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy
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NCT03417726

  Evaluation of Pediatric Balance Scale and Quantitative Balance Parameters in Patients With Cerebral Palsy
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NCT03419403

  A Study for Management of Ocular Side Effects in Subjects With Glioblastoma Receiving Depatuxizumab Mafodotin
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NCT03451123

  FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors
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  Nivolumab Plus Standard Dose Bevacizumab Versus Nivolumab Plus Low Dose Bevacizumab in GBM
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NCT03452930

  EDO-S101 for MGMT Unmethylated Glioblastoma (nGBM)
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NCT03458312

  Nurse-led Family and Network Consultations
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NCT03460067

  Omission of Radiation in Patients With Her-2 Positive Breast Cancer
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NCT03465423

  Comparison of Propofol Requirement Between Patients With Pituitary Somatotroph Tumor and With Nonfunctioning Pituitary Tumor in Transsphenoidal Pituitary Surgery Under Total Intravenous Anesthesia
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NCT03471026

  Advanced MRI for Posterior Fossa Tumours
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NCT03477110

  Temozolomide, Radiation Therapy, and Tumor Treating Fields Therapy in Treating Participants With Glioblastoma
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NCT03483012

  Atezolizumab + Stereotactic Radiosurgery in Triple-negative Breast Cancer and Brain Metastasis
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NCT03484104

  Cerebral Perfusion in Hypothermic Circulatory Arrest
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NCT03526809

  Molecular Imaging and Spectroscopy With Stable Isotopes in Oncology and Neurology
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NCT03526822

  Prospective Cohort of Patients With Newly Diagnosed Glioblastoma: Analysis of MMP2 and MMP9 Expression and Correlation to Neuro-imaging Features.
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NCT03531307

  Lactate Levels Correlates With Ki-67 in Brain Tumor Surgery
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NCT03531333

  Intraoperative Ultrasound Guided Glioma Surgery; a Randomised, Controlled Trial.
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NCT03535350

  Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma
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NCT03539731

  [18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers
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NCT03542409

  Safety and Feasibility of Preoperative and Intraoperative Image-Guided Resection of Gliomas
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NCT03546387

  Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients
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NCT03548571

  Dendritic Cell Immunotherapy Against Cancer Stem Cells in Glioblastoma Patients Receiving Standard Therapy
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NCT03496402

  Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO)
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NCT03503422

  Optimizing Chronic Low Back Pain Exercise Therapies With Cerebral Electrical Stimulation
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NCT03510208

  Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery
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NCT03516162

  Linking Digital Smartphone Behaviour With Brain Function
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NCT03556384

  Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)
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NCT03561207

  3D-Prediction of Patient-Specific Response
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NCT03493932

  Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade
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NCT03458676

  Radiologic Pathologic Correlation of Advanced MR Imaging to Guide the Biopsy of Cerebral Malignancies
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NCT03463733

  Hydroxy-urea and Temozolomide in Patients With a Recurrent Malignant Brain Tumor (Glioblastoma)
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NCT03480867

  Pre-operative RT and TMZ in Patients With Newly Diagnosed GBM Diagnosed Glioblastoma. A Phase I Study. (PARADIGMA)
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NCT03412877

  Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in People With Metastatic Cancer
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NCT03414944

  Elective Simultaneous Modulated Accelerated Brain Radiation Therapy for NSCLCs With Limited Brain Metastases
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NCT03426891

  Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma
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NCT01166321

  Carbon Ion Radiotherapy for Atypical Meningiomas
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NCT01360606

  Stereotactic Body Radiation Therapy (SBRT) for Liver Mets
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NCT01433588

  The Calmer Project
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NCT01880632

  Oxaliplatin Plus Capecitabine in the Perioperative Treatment of Locally Advanced Gastric Adenocarcinoma
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NCT01904123

  Trial of WP1066 in Patients With Recurrent Malignant Glioma and Brain Metastasis From Melanoma
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NCT02129647

  Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas
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NCT02321917

  Rheoparin-coated Tubing System for Minimized Extracorporeal Circulation (MECC)
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NCT02898727

  A Study of Local Therapy for the Treatment of Brain Metastases From HER2 Positive Breast Cancer
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NCT03267836

  Neoadjuvant Avelumab and Hypofractionated Proton Radiation Therapy Followed by Surgery for Recurrent Radiation-refractory Meningioma
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NCT03277638

  Laser Interstitial Thermotherapy Combined With Checkpoint Inhibitor for Recurrent Glioblastoma
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NCT03286335

  Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy
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NCT03347617

  Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With Brain Tumors From Melanoma and Glioblastoma
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NCT03370926

  FET-PET and Multiparametric MRI for High-grade Glioma Patients Undergoing Radiotherapy
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NCT03367715

  Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma
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NCT03387020

  Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors
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NCT03405792

  Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP)
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NCT03407781

  IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With Lower Grade Glioma
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NCT03231501

  HMPL-813 in Treating Patients With Glioblastoma
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NCT03285932

  Stereotactic Radiotherapy of the Resection Cavity of Brain Metastases vs. Post-operative Whole-brain Radiotherapy
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NCT03297788

  Whole Brain Radiation Therapy Alone vs. Radiosurgery for SCLC Patients With 1-10 Brain Metastases
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Brain Tumor News Articles About Surgery

  1. [01/10/2020] Surgery may add months or years of survival for adults with rare and deadly brain cancers  This report says it may now be possible to safely surgically remove high grade brainstem gliomas. This could almost double the expected average survival, which buys time for other treatments to work!  

  2. [01/04/2020] Complete radiological response following subtotal resection in three glioblastoma patients under treatment with Tumor Treating Fields.  This is a relatively small trial but shows a huge effect supporting the use of Optune for Glioblastoma.   In the big EF-14 phase 3 trial for newly diagnosed glioblastoma, the trial was stopped at the first interim analysis because it was obvious the Optune arm was doing so much better than the control group that it was unethical to continue withholding Optune from newly diagnosed patients.    The people running this study did not do that - they allowed it to go on for 5 years - knowing that they were withholding the best treatment.  Doesn't sound fair to me.

  3. [11/18/2019] Extensive brainstem infiltration, not mass effect, is a common feature of end-stage cerebral glioblastomas.  Fascinating.   Important finding - looking at how the current treatments change the natural course of the disease.   This opens the door to new ways to treat GBMs.  Prevent the infiltration.

  4. [10/10/2019] First-line treatment of ONC 201 in newly diagnosed DIPG pediatric patients is now open.  There are a few trials of this drug, as well as the compassionate use program, but a new trial opened that requires DIPG patients to start before radiation. It is hard to get the word out to those patients since things happen so fast when first diagnosed and most families are in shock.  So if you hear of a patient diagnosed with DIPG, mention this trial to them as an option. Disclaimer:   The Musella Foundation gave a venture philanthropy grant to the company that makes Onc-201 - which means the foundation gets a return if the drug is successful.

  5. [09/30/2019] Optune Open House  From our good friends at Novocure!  These Open Houses are valuable to anyone who has a brain tumor or knows someone with a brain tumor!  

  6. [08/15/2019] Attend an Optune Open House  From our friends at Novocure.  These open houses are fun and informative!  Worth attending for anyone who has or knows someone with a gbm. Most are live but there are webinar versions in there for people not near a live site!

  7. [07/29/2019] Dramatic response of BRAF V600E-mutant epithelioid glioblastoma to combination therapy with BRAF and MEK inhibitor: establishment and xenograft of a cell line to predict clinical efficacy.  This is only in mice right now but if you happen to have these 3 mutations, which signify a pretty much hopeless situation, it might be worth trying this combination of drugs.

  8. [07/16/2019] Attend an Optune Open House.  From our friends at Novocure!   

  9. [07/06/2019] Insurance type impacts the economic burden and survival of patients with newly diagnosed glioblastoma.  As expected, the better insurance you have the better you will do.  This is very significant when we start talking about Medicare for all.  The most popular "medicare for all" plan really is Medicaid for all. It sounds good with no copayments or deductibles, but when you try to limit costs especially for complex cases like a brain tumor, quality has to suffer. One fault in the article- it says Medicare patients do not live as long as private insurance payments, but they did not correct for age.  Medicare patients are usually older than private insurance patients, especially at the time of the first surgery.  Older people in general do not do as well as younger people.    

  10. [06/10/2019] Attend an Optune Open House.  These meeting are to learn about Optune and meet people who are using it!  One of them can be done online, the rest are real wolrd. Very much worth attending if you have a GBM or know someone who has one!

  11. [05/16/2019] Optune Open Houses  These meetings are for anyone who uses or is thinking of using Optune.  Most of these are live but there are some broadcast on the web!  

  12. [04/29/2019] Optune Open House  Here is an updated list of the Optune Open Houses.   These meetings are interesting and a lot of fun for everyone who has  a brain tumor.

  13. [04/09/2019] Optune Open Houses

    This is a chance to learn about Optune - or for those of you using it - to meet others using it and swap tips and ask the experts any questions you have!  Most are live but the last one is a webinar.

  14. [03/14/2019] Optune Open Houses
    These are informative and fun meetings. Some of them are webinars available online for those not close to a live meeting.  All are free.  They are sponsored by Novocure and the Musella Foundation is not involved - I am just letting you know about them because they are important!  


  15. [03/09/2019] Optune Open House These are nice meetings if you are using Optune or are considering it!  

  16. [02/23/2019] Improved survival of glioblastoma patients treated at academic and high-volume facilities: a hospital-based study from the National Cancer Database.  This shows what we already assumed:  getting treated in a academic center with a high volume of brain tumor patients will result in a better outcome.

  17. [02/13/2019] Progesterone is more effective than dexamethasone in prolonging overall survival and preserving neurologic functions in experimental animals with orthotopic glioblastoma allografts.  An alternative to dexamethasone is badly needed, especially when using immunotherapies or Optune.  This may be one such alternative but the experiment was done in rats.  Need to wait until it is tested in people before using it.  

  18. [01/18/2019] Optune Open House, Newton, MA  These are great get togethers for any brain tumor patient or anyone who knows a brain tumor patient!  

  19. [12/13/2018] Tumor treating fields increases membrane permeability in glioblastoma cells.  This show a different possible method of action for Optune.

  20. [11/22/2018] The impact of traveling distance and hospital volume on post-surgical outcomes for patients with glioblastoma.  This paper shows that it is worth traveling to a major brain tumor center.

  21. [10/17/2018] PVSRIPO (Polio Vaccine) clinical trial now open in 4 brain tumor centers!  This is one of my favorite trials and has just opened up in CA, MA and FL in addition to NC. The pediatric version is still only in NC. Disclaimer: I am on the advisory board of the Preston Robert Tisch Brain Tumor Center at Duke University, and have given grants towards these projects.

  22. [10/12/2018] Checkpoint Blockade Reverses Anergy in IL-13Ra2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas.  This type of treatment worked miracles in other types of cancer. The first attempt in human glioblastoma wasn't spectacular but these researchers may have found a way to make it work at least in dogs and rats.  Lets hope it translates to people! 

  23. [10/04/2018] Novocure Announces 55 Presentations at European Association of Neuro-Oncology Meeting 2018

    This shows that Optune has finally hit the mainstream.  55 presentations at the major European brain tumor conference.  Many of these are looking at ways to improve the outcomes, including new types of arrays, new placement of arrays for tumors lower in the skill and for pediatric patients.

  24. [09/17/2018] Inhibition of Radiation and Temozolomide-Induced Invadopodia Activity in Glioma Cells Using FDA-Approved Drugs.  I love this type of research.  Invadopoia are small projections from the edges of tumnor cells that help allow them to move.  Without the ability to move, the tumor is much less dangerous and more sensitive to normal treatments. This is a highly underappreciated target and they found 2 existing drugs which may target this.  Of course, it is just theory now and needs to be tested but it is a promising approach!

  25. [08/29/2018] Optune open house Seattle, WA  These are always very interesting and worth going for anyone dealing with a brain tumor.

  26. [08/24/2018] New glioblastoma clinical trial: mTOR inhibitor ABI-009  This is a new trial for newly diagnosed GBM or recurrent high grade glioma in adults (age 18+).

  27. [08/16/2018] 5-Aminolevulinic acid fluorescence guided surgery for recurrent high-grade gliomas.  This is a dye used at the time of surgery to allow the surgeon to better setermine the difference between tumor and non tumor, allowing for a better chance at a total resection.   A total resectionn is associated with longer survival times.  It is now FDA approved and readily available!

  28. [07/21/2018] Webinar on brain cancer vaccines Sunday July 22, 2018!  These clinical trials are for both newly diagnosed  GBM and recurrent GBM and Anaplastic Astrocytoma (and variants) . You will be able to ask any brain tumor related questions.  

  29. [06/02/2018] Returning to work after multimodal treatment in glioblastoma patients.

    Returning to work after multimodal treatment in glioblastoma patients.         This is one of the most important outcome of brain tumor treatments. It should be considered an important primary endpoint for clinical trials: what % of patients  are able to work full time at the level of their previous job at 1,2,3 year point? What % of patients can work at least part time at any job at 1,2,3 years.  This is important because for the first time, we are seeing long term survivors of GBMs who can actually work full time at high level jobs, many years down the line.  Even if a treatment only improves median survival by a small amount, but allows those who do survive to engage in meaningful work - that is a breakthrough. For example, many years ago there were reports of a high % of long term survivors with intense radiation.  However, it caused so much damage that most survivors were bedridden for the rest of their lives.  More recently, with DC-Vax, ICT-107, Toca 511 / Toca FC, and others, we see some long term survivors who are functioning at the highest level - executive jobs, having families, driving and enjoying life.   That is what we strive for. So it should be a formal endpoint!

  30. [05/29/2018] First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma
    This article is so important that I am placing my editorial comments into the full text part of this entry so more people see it, along with a link to the full article.


  31. [05/13/2018] When did the glioblastoma start growing, and how much time can be gained from surgical resection? A model based on the pattern of glioblastoma growth in vivo.  Fascinating. We get this question all of the time. The answer is it takes about a year for the gbm to grow to the size where it causes symptoms and you notice it.   And there is a big gain from removing 99% of the tumor compared to 95%.  If they only remove 50% of the tumor, it will grow back before the surgery heals.

  32. [05/13/2018] VA tightens oversight after outrage over conducting experiments on dogs, then killing them  Please  fill out our survey on this topic!  https://virtualtrials.com/surveyresearch.cfm

  33. [05/12/2018] Brain Tumor Awareness Week 2018 Webinar Series - Tonight! 7pm Eastern  Just a reminder!  

  34. [03/20/2018] NCCN Guidelines Recommend Optune in Combination with Temozolomide as a Category 1 Treatment for Newly Diagnosed Glioblastoma  This is great news.  The NCCN basically sets the standard of care for cancer treatments. The NCCN treatments classification is:

    NCCN Categories of Evidence and Consensus

    • Category 1: Based upon high-level evidence, there is uniform NCCN consensus that the intervention is appropriate.
    • Category 2A: Based upon lower-level evidence, there is uniform NCCN consensus that the intervention is appropriate.
    • Category 2B: Based upon lower-level evidence, there is NCCN consensus that the intervention is appropriate.
    • Category 3: Based upon any level of evidence, there is major NCCN disagreement that the intervention is appropriate.
    Not only does this set the standard of care as including Optune, but it should make it impossible for insurance companies to deny it.

  35. [03/09/2018] Optune Open House  This is from the people at Novocure.  It is a facebook event where you can learn about and ask questions about Optune!

  36. [02/28/2018] Advantages and disadvantages of combined chemotherapy with carmustine wafer and bevacizumab in patients with newly diagnosed glioblastoma: A single institutional experience.  This is a small study - so it can't be relied on completely. However, it shows that adding both Gliadel and Avastin to the standard Temodar for newly diagnosed GBM added 9 months to average survival and doubled progression free survival. Another tidbit - more than half of patients operated on in this hospital in Japan received Gliadel wafer.  

  37. [02/24/2018] Tumor microenvironment after biodegradable BCNU wafer implantation: special consideration of immune system.  Very interesting.   If this is true,  this may lead to big gains in immunotherapies.  One of the problems was the lack of CD8+ Killer T Cells in the area of the tumor. Apparently, Gliadel wafer may attract these cells to the tumor bed.  So we need to watch combinations of Gliadel with immunotherapies! Very exciting!

  38. [02/14/2018] Thoughts on "Right To Try"  These are my thoughts on the right to try law. The Senate passed it already and the House is considering it.   

  39. [01/29/2018] Optune Open House, Santa Anna, CA  This is from the people at Novocure. These meetings are a perfect introduction to Optune for brain tumor patients thinking about trying it or those who are using it!  

  40. [01/21/2018] Lessons Learned Using a High-definition Three-dimensional Exoscope for Brain Tumor Surgery  Very cool video of a new tool for brain tumor surgery. Warning - very graphic.

  41. [12/19/2017] JAMA Publishes Final Analysis of EF-14 Phase 3 Pivotal Trial of Optune® Together with Temozolomide Demonstrating Unprecedented Survival Results for Newly Diagnosed Glioblastoma  This is the final report of the Optune trial for newly diagnosed GBM.  It should set the new standard of care for GBM to include Optune.

  42. [11/21/2017] Local alkylating chemotherapy applied immediately after 5-ALA guided resection of glioblastoma does not provide additional benefit.  This showed no benefit of adding Gliadel when 5-ALA was used to guide the surgery. Surprising results. 

  43. [09/24/2017] Combination of Optune® with Temozolomide Demonstrates Unprecedented Five-Year Survival for Newly Diagnosed Glioblastoma Patients  The 5 year results for Optune just came out and they were unbelievably good.  This is a large study in newly diagnosed GBM patients so the results are significant. Bottom line: 5 year survival rate was 13% for the Optune (plus Temodar) group and only 5% for the Temodar alone group.  That is a major step forward.

  44. [09/07/2017] Curtana Pharmaceuticals Successfully Completes Pre-IND Submission for CT-179 for the Treatment of Malignant Gliomas  This sounds exciting - it is a new target which is not usually found on normal brain but is found in GBM cells - especially cancer stem cells

  45. [08/16/2017] CHOP to lead new pediatric data resource center for research in childhood cancer, birth defects  This is the type of effort needed to make headway in the fight against cancer (and birth defects).   The Musella Foundation funded early work for this project which led to the big NIH grant which is making it a reality!

  46. [08/15/2017] Curtana Pharmaceuticals Granted FDA Orphan Drug Designation for CT-179 for the Treatment of Gliomas  This targets Oligo2, which sounds like it might be a great target 

  47. [08/14/2017] Options to Treat a Glioblastoma  I was asked for my opinion on what I would do if I had a newly diagnosed gbm.. here is my response.  We can discuss it in the braintumor-treatments online group https://virtualtrials.org/braintumor-treatments.cfm  

  48. [07/29/2017] Early initiation of chemoradiation following index craniotomy is associated with decreased survival in high-grade glioma.  Very interesting study. It says that starting radiation therapy earlier than we usual do actually is worse for the patient. The study was performed just by looking at billing records.  I would like to see more research on this. Perhaps look at the reasons radiation was started earlier. Maybe those patients had a lot of residual tumor so they were rushed into radiation as there was less space for recurrence? Or had some other medical reasons.

  49. [06/12/2017] First Patient Enrolled in RTOG Trial of Optune® together with Bevacizumab for Patients with Bevacizumab-Refractory Recurrent Glioblastoma  Interesting combination.  I would guess the concept they are going after is that Avastin, when it fails, doesn't just stop working - it just doesn't work enough but still is slowing down the tumor.  If you add Optune, perhaps the combination could be strong enough to stop the tumor.  Hate to say, but it may make more sense to just start Optune at the start - right after radiation - on newly diagnosed people.  For those that missed that opportunity, this trial makes sense. [Disclaimer: Novocure is a sponor of our organizaiton]

  50. [06/08/2017] FDA has approved Gleolan  This allows for a more complete resection!  If you are going to have a brain tumor surgery, ask your neurosurgeon about this to see if it is appropriate for your case!

  51. [05/25/2017] Four Neuro-Oncology Experts to Lead New Glioblastoma Research Center at NewYork-Presbyterian  These are some of the brightest minds in the field. Great to see them working together!

  52. [04/26/2017] Surgical success in previously “inoperable” brain cancers  This may be an option when you are told a tumor is inoperable. Disclosure: this company is a sponsor of the Musella Foundation

  53. [04/17/2017] CNS Oncology Publishes Data Suggesting Survival Benefit of Optune™ in Combination with Second Line Chemotherapies after Glioblastoma Recurrence  This study shows that Optune should be continued after the first recurrence, and use it in addition to a second line therapy.  Patients who had a recurrence and remained on Optune therapy did 31% better than those that discontinued Optune.

  54. [04/14/2017] Medicenna Treats First Patient in Phase 2b Recurrent Glioblastoma Trial  This is an exciting trial.  Early (small)  trials had a few complete responses after a single treatment. Disclaimer: Medicenna is a sponsor of our organization

  55. [04/12/2017] Feinstein Institute examines use of antiparasitic drug as new treatment for brain tumors  Brilliant work.  If they are correct, this drug may be able to replace the Vincristine in PCV, making it more effective and much less toxic! Disclosure: I am on the patient advisory board of the Feinstein Institute.

  56. [03/17/2017] Limited role for extended maintenance temozolomide for newly diagnosed glioblastoma.  This article says that using more than 6 months of Temozolomide is not better than using 6 months of it as far as survival goes. That is counter-intuitive.  I would like to see larger studies to confirm it.

  57. [03/10/2017] Role of MGMT Methylation Status at Time of Diagnosis and Recurrence for Patients with Glioblastoma: Clinical Implications.  Good project, but I disagree with their conclusion.  They found that 25% of the time, the methylation status changes between the first and second surgery.   They conclude that it is insignificant and we shouldn't bother testing the second time as it provides no useful information.  They are correct for now, but  that should change very shortly as there is now a drug in clinical trials that can work on unmethylated patients. This makes the methylation status very important to determine, and for those 25% of patients with the changed status, it can be a life altering test.

  58. [02/04/2017] Northwell Health is First on Long Island to Acquire Synaptive Medical’s BrightMatter™ Technology for Complex Brain Tumor and Spinal Surgery  This technology will help make braintumor surgery safer, and may also make some tumors that were thought inoperable, operable! Disclosure: I am on the patient advisory board of this medical center!

  59. [02/04/2017] FDA Grants New Clearance for Brain Surgery Technology  These 2 new approvals should help make brain tumor surgery safer, and also may turn some inoperable tumors into operable ones!

  60. [01/28/2017] The Musella Foundation announced that it has awarded a $25,000 brain tumor research grant This project involves a new material that can be 3-d printed into the shape of a bone flap, which can be inserted when the original bone flap created during a brain tumor surgery, can't be used (such as for infections or necrosis).  This new material quickly transforms into real bone.

  61. [01/25/2017] Correction to: Brain Surgery Made Safer With New Smart Needle  Sorry - the link I posted yesterday had a space in it and didn't work. It is now fixed.

  62. [01/24/2017] Brain Surgery Made Safer With New Smart Needle  Amazing technology.  Hope it becomes available soon!

  63. [01/19/2017] Novocure’s Optune® Now Available at 500 Cancer Treatment Centers in the U.S.  That is amazing, as doctors have to take a course to get certified in the use of Optune. This means that practically every major brain tumor center in the USA can offer Optune to their patients.    There was a 70 percent increase in the survival rate at 4 years for newly diagnosed GBM patients, and Optune is now considered the standard of care for newly diagnosed gbms!

  64. [12/25/2016] First patient enrolled in brain tumor trial combining 9 repurposed drugs - CUSP9v3 project  This is the 3rd version of CUSP9... it appears that they are only taking patients from Germany at this time, however, since all of the treatments are already approved and readily available, it can be done outside of that trial. If you try it, please register for our virtual trial project first at virtualtrials.com. That way we can track results. 

  65. [12/19/2016] Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic.  Aside from the mechanism of action these authors proposed, perhaps the theories about cytomegalovirus playing a role in GBMs are valid, and this drug also fights the CMV, just like Valcyte does.

  66. [12/13/2016] Medicenna Announces Initiation of Phase 2 Clinical Trial of MDNA55 for the Treatment of Recurrent Glioblastoma  (Disclosure: Medicenna is a new sponsor of the Musella Foundation).   This immunotherapy had some very impressive results in a small early trial. Of course we have to be careful when there are small numbers involved - sometimes that doesn't pan out when the large trials are done, but it is a good sign.  In a group of patient with recurrent gbm who did not have a resection at the time of recurrence, just one infusion of this new treatment, they had 20% complete response rate.  That means the tumor disappeared after just one infusion.  The response rate was 56% and if you include stable disease, the benefit rate (Stable + partial response + complete response) was 68%.   They were no serious safety problems. This treatment is a fusion protein which targets Interleukin-4 which is overexpressed on 3/4 of GBMs, and 100% of brainstem gliomas. It carries along a toxin that can kill the cells which overexpress IL-4. Normal cells have a low level of IL-4. Delivery is via convection enhanced delivery.  Prior trials involving CED have failed, mainly because the early versions of CED were not accurate - they couldn't get the drug to the target.  The Tocagen trials proved that CED is now at a point where they can routinely get the treatment 

  67. [11/18/2016] Long-Term Analysis of All 695 Patients Enrolled in Novocure’s Phase 3 Pivotal Trial in Newly Diagnosed Glioblastoma Confirms Successful Interim Analysis Results and Demonstrates Superior Two- and Four-Year Survival Rates  This is what we have been waiting for. The final results of the Optune trial for newly diagnosed GBM.  There was some resistance to accepting Optune as the standard of care because the results presented 2 years ago were "just preliminary". The final results are actually better than the preliminary results! Now the next step is getting insurance to pay for it. Already most non-Medicare plans do pay for it, but Medicare has been hesitating. We had a petition a while ago to help nudge Medicare toward paying for it.  I presented it to them and we did come close and I think it did help - but we had that problem of results being preliminary.  We are going to try again. I resurrected the survey - and updated it to show current results.  Please sign it and have your friends and family members sign it.  IF you already signed it last time - you do not need to sign it again - it is still valid.  If you aren't sure, email me your name and address and I will check it for you.  Go to https://virtualtrials.com/activism.cfm for details and to sign! 

  68. [11/07/2016] United Healthcare Issues Positive Coverage Decision for Optune This has been a big battle to get insurance to pay for Optune.  United Healthcare was basically the last private insurance that didn't pay - now almost all do.  Next up is the Medicare battle.  I have been working on that one for a while and getting closer. I may need your help soon - we are thinking of another petition campaign!

  69. [11/07/2016] Novocure Announces 38 Presentations on Tumor Treating Fields at 21st Annual Scientific Meeting of the Society of Neuro-Oncology  It looks like Optune is finally getting the respect that it deserves. When it was first introduced, I would say most neuro-oncologists dismissed it without looking at data, based solely on preconceived notions that it couldn't possible work.  Now, most seem to at least allow their patients to try it, if not encourage them to try it.  The holdouts tell me that the data is preliminary and they will wait for the full report. Well - that will come out next week!  I did not see it yet, but I assume from this press release that it is favorable.  Hopefully that will remove the last doubt that this should be part of the standard of care for newly diagnosed Glioblastomas. It is very significant that most of the presentations are from researchers not associated with the company.  That shows broad acceptance in the field. 

  70. [10/09/2016] CIK Treatment Extends Progression-free Survival of Glioblastoma Patients by 1.5 Times  Impressive results in a large controlled trial.

  71. [10/09/2016] Darren Daulton Battling Brain Cancer Through Charitable Foundation  This organization offers brain tumor (and brain injury) patients up to $5,000 per year to help with expenses! Great work!

  72. [10/01/2016] Pioneering Studies Apply New Immunologic Insights to Glioblastoma  This is a completely new way of trying to treat brain tumors by suppressing cells in the blood that travel to the brain tumor and inhibit the immune system.  We (The Musella Foundation) funded part of the project!  This is YOUR donations hard at work! Thanks  

  73. [09/26/2016] Orbus Therapeutics Announces Enrollment of First Patient in Phase 3 Trial in Late-Stage Brain Cancer  Interesting drug. It is approved for uses other than cancer, so if this trial shows it works, access will be easy. I am not sure about the statistics they use.. they say anaplastic astrocytoma was the largest subset of anaplastic glioma, but Glioblastoma multiforme is.  They say 75% of the 20,000 cases of anaplastic glioma are 2,700 anaplastic astrocytomas..  but 75% of 20,000 is 15,000.. 

  74. [09/19/2016] CNS Oncology Publishes Tumor Treating Fields Treatment Planning and Patient Follow-up Guidelines in Glioblastoma This should make the treatment work better - especially for those offices that do not have a lot of experience with using Optune

  75. [09/08/2016] Monteris Medical Receives IDE Approval From FDA To Evaluate NeuroBlate® In Patients Newly Diagnosed With Glioblastoma Multiforme  This trial will be for patients with newly diagnosed GBM who are told the tumor is inoperable. This is a form of laser surgery where a small hole is made in the skull and a special probe is inserted to destroy the tumor. It can sometimes be done in locations that were though impossible to treat using regular surgery. The Neuroblate system is already available all over the USA.  You can find a doctor near you at http://mybrainsurgeryoptions.com/directory/locations/    [Disclosure: Monteris is a sponsor of the Musella Foundation]

  76. [09/07/2016] The fourth weapon in the battle against cancer  Nice story about one of the members of our online support group (Brain-novocure)! To join the group, go to https://virtualtrials.com/lists.cfm and select brain-Novocure

  77. [08/23/2016] Curcumin Changes the Polarity of Tumor-Associated Microglia and Eliminates Glioblastoma.  This is only in mice now but looks exciting.

  78. [08/16/2016] Novocure Converts More Than 500 U.S. Patients to Second Generation Optune within Four Weeks of FDA Approval on July 13 This should make the Optune system easier to use.

  79. [07/26/2016] International Study Finds Effective, Less Toxic Way to Treat Brain Tumors  I love this type of research. They took into account the patient's quality of life as well as survival time to determine that for 1 to 3 brain metastases, stereotactic radiosurgery is better used alone rather than in combination with whole brain radiation.  The survival times were about the same either way, but quality of life was better with radiosurgery alone. Not to mention a lot cheaper and more convenient.

  80. [07/26/2016] NCCN Guidelines Recommend Optune as a Standard Treatment Option for Newly Diagnosed Glioblastoma  I sent a story about this in a recent news blast but this is the press release from Novocure and their take on the topic!

  81. [07/13/2016] Novocure Receives FDA Approval for Second Generation Optune System  I have seen the new system, and it is much nicer. Smaller, lighter, looks much more modern, and is easier to use.  

  82. [07/04/2016] Scientists just discovered we`ve been looking at cancer growth all wrong. This could change everything.  This is still preliminary work, but raises an important point: that we should recheck everything that we thought we knew about these tumors.  The technology we have now is amazing compared to what was available in the 1950s when it was decided that brain tumors use glucose as the main energy source. This article points out that by culturing the tumor cells in blood, you change the tumor cells to use what is most common in the blood, which is different than what is in the brain. On the other hand, they also mention that PET scans show where glucose is being used - and the tumors do use a lot more glucose than non tumor brain.

  83. [06/29/2016] Rapid regression of glioblastoma following carmustine wafer implantation: A case report.  You can never make decisions based on individual case reports but they are nice to see.  Gliadel has been neglected by some medical centers.  On average, it adds a little extra time before the tumor progresses, sometimes allowing time for other treatments to have a chance at working. It was never meant to be a cure by itself.  We do not have enough patients in our brain tumor virtual trial (virtualtrials.com) to make a statistically significant statement about it, but taking a look at just our  long term (over 5 year) GBM survivors,  5 out of the 21 (24%) have used Gliadel as part of the plan. Looking at all GBM patients, 36 out of 469 (8%) have used Gliadel. To me this means that if Gliadel had no effect, you would expect the same % of patients who used it as the % of long term survivors who use it. But we see a tripling of the %, which means Gliadel does have a big increase (possibly tripling) in the chances of becoming a long term survivor, and it should be studied more in depth.  

  84. [05/31/2016] Novocure Receives IDE Approval to Initiate METIS Trial  This sounds like a great combination. Radiosurgery can usually control an individual brain met over 90% of the time, however the patient usually still develops new mets in the brain - because the radiosurgery doesn't do anything for the little islands of tumor cells that you can't yet see on the scans.  The TTFields might be able to stop those islands from developing into new tumors.  

  85. [05/05/2016] Innovative Hypofractionated Stereotactic Regimen Achieves Excellent Local Control with No Radiation Necrosis: Promising Results in the Management of Patients with Small Recurrent Inoperable GBM.  This sounds like an ideal treatment for small recurrent gbms. They had local control (of the treated tumor) in over 90% of the tumors, although most people eventually died of tumors growing outside of the treated areas.   None had radiation necrosis which happens frequently with single fraction sterotactic radiosurgery.  This may work well in combinations with other treatments to give them time to work.

  86. [04/27/2016] Research findings could lead to treatment for deadly brain cancer  Sounds like an exciting new approach

  87. [04/27/2016] Novocure’s Optune Now Available at More Than 360 Cancer Treatment Centers in the U.S.  Looks like Optune should now be available to just about everyone.

  88. [03/03/2016] Humana Issues Positive Coverage Decision For Optune  Humana insures 10 million people in the USA, and now all of these people have access to Optune if they need it!    

  89. [02/14/2016] Phase 2 multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma.  Excellent result. For the group with total resections, this  increased the chances of being alive at the 3 year point from 6% in the control group to 32% in the gene therapy group. Amazing.

  90. [02/14/2016] Anthem Inc. Issues Positive Coverage Decision For Optune in Newly Diagnosed Glioblastoma

     Great news.   

    Now that the 3 largest private health insurance carriers in the USA cover Optune, the rest should follow suit soon!  This is a major victory in the fight against brain tumors. We thought the hard part was going to be getting FDA approval because it is a completely new type of treatment, but that actually was easy since the data supported it.  Once that happened, I assumed patients would be able to just get it but the timing was terrible. Insurance companies have just started fighting back against expensive treatments and started denying all new treatments as a way of saving money until they are forced to pay for them. It was a long, hard battle but the people at Novocure persevered and won the battle with the private insurers.

    Next up is Medicare. I had multiple meetings with Medicare and they are getting close to approving payment. The people I met with at Medicare understand that brain tumor patients need this treatment and they are trying to find a way to pay for it. Having the majority of private insurance companies paying for Optune, along with the recent publication of data in the Journal of the American Medical Association, should allow patients to appeal Medicare rejections successfully. IF you have a problem with a Medicare rejection, call me at 888-295-4740 and maybe I can write a letter for you to help with the appeal.

  91. [02/10/2016] Cancer Surgery At Low-Volume Hospitals In California  Very scary.  The point is that brain tumor surgery should only be done by experienced  neurosurgeons. 

  92. [02/10/2016] Brain tumor movie - looking for volunteers!  These people are trying to create a movie about brain tumors and are asking for help - they need patients and doctors to volunteer to be interviewed..  

  93. [01/19/2016] Neurosurgeons Evaluate Precision Laser Treatment Of Brain Tumors at UC San Diego Health  This trial is available at many locations. See clinicaltrials.gov/ct2/show/NCT02392078 for details

  94. [01/06/2016] Novocure Files Premarket Approval Supplement Application With FDA for Second Generation Optune System  I saw the new system, and it looks like it will make using the system a lot easier!

  95. [11/22/2015] Groundbreaking Global Brain Cancer Trial Planned

           I tried to get something very similar off the ground years ago, but couldn't raise the money needed for it.  I had the major brain tumor centers and another brain tumor foundation willing but it was too expensive for us.  I hope this group does well. I think it is the fastest and cheapest way to find the best drugs and combinations.

  96. [11/20/2015] ImmunoCellular Therapeutics Ltd Presents Updated ICT-107 Phase 2 Survival and Immune Response Data at the Society for Neuro-Oncology Annual Meeting 2015  Good  news from the SNO meeting: Although they did not hit the original target of overall survival for all patients in the trial, they found a subgroup of patients where the vaccine worked very well. Newly diagnosed GBM patients with a blood type of HLA-A2+ did very well. If the MGMT methylation status was positive, there was a 58% increase in survival compared to the control group. If the MGMT status was negative, there was a 34% increase in survival.  This is for a treatment that is just a simple shot in the arm and once approved, could just be added to other treatments. They just started a new phase 3 trial that will require patients to be HLA-A2+.  This should show a big improval.

  97. [11/20/2015] New Phase 3 Data show Optune in Combination with Second Line Chemotherapy is Superior to Second Line Chemotherapy Alone in Glioblastoma Patients at First Recurrence  This is a new report on combining Optune with Avastin. Both are approved for recurrent GBM. The combination reduced the chance of dying by 39% compared to Avastin alone.  This should be the standard for recurrent gbm and investigated for newly diagnosed.

  98. [11/17/2015] Novocure Announces 18 Presentations on Tumor Treating Fields at SNO 2015 Including New Analyses of the EF-14 Newly Diagnosed Glioblastoma Clinical Trial Data Amazing number of presentations for Optune. So glad to see the brain tumor community finally embracing this new treatment option!

  99. [11/06/2015] Targeted treatment produces rapid shrinkage of recurrent, BRAF-mutant brain tumor  This is only in 1 patient so far but may lead to a major breakthrough in the treatment of this tumor type since they reported that nearly all patients with this tumor type have the mutation this drug targets.

  100. [10/30/2015] Does Early Postsurgical Temozolomide Plus Concomitant Radiochemotherapy Regimen Have Any Benefit in Newly-diagnosed Glioblastoma Patients? A Multi-center, Randomized, Parallel, Open-label, Phase II Clinical Trial.  This has an interesting result: Using Temozolomide right after surgery compared to waiting until radiation starts resulted in a big increase in median overall survival, but a decrease in progression free survival.  It makes a lot of sense to me to start the Temozolomide right away (although we have to study the effect on wound healing), but more research is needed to see why the progression free survival goes down while the overall survival goes up. 

  101. [10/05/2015] FDA Expands Optune`s Glioblastoma Multiforme Indication  Fantastic news! The FDA acted quickly! They approved Optune for Newly Diagnosed Glioblastoma to be used in addition to the standard treatment!  It results in "the risk of progression or death was reduced by 37 percent "

  102. [10/01/2015] Multicenter study shows Monteris’ NeuroBlate System improves outcome in brain tumor patients This is a relatively new, FDA approved robotic laser surgery. This article mentions the ability to target tumors in very hard to reach areas.

  103. [09/20/2015] EnGeneIC Ltd. to Initiate U.S. Phase 1 Clinical Study Using Targeted EDV™ Nanocells to Treat Advanced Glioma Patients  Sounds interesting

  104. [09/12/2015] Novocure to Present the Latest Data from the EF-14 Clinical Trial in Newly Diagnosed GBM at the 15th Interim Meeting of the World Federation of Neurosurgical Societies  This updated the results that were presented last year.  They still look great!

  105. [09/01/2015] UCLA Researchers Develop a Likely New Combo Treatment for the Deadliest Form of Brain Cancer  This is an amazing concept. Hope it works out.

  106. [07/18/2015] The Efficacy of Ketogenic Diet and Associated Hypoglycemia as an Adjuvant Therapy for High-Grade Gliomas: A Review of the Literature.  One of the common questions I hear about brain tumors is what diet should I be following.   I never really was convinced that diet made much difference but we are seeing more evidence that it may.  This article says that the Ketogenic diet in animal models increases survival. In humans there isn't enough information on survival yet but the diet was found to be well tolerated and let to a higher quality of life. It may be worth considering.

  107. [06/27/2015] IBTA Newsletter  From our good friends at the IBTA

  108. [06/05/2015] The Musella Foundation announced that it has awarded Tocagen Inc. a grant to support preclinical testing the compatibility of Tocagen’s therapy with 5-ALA or tumor treating fields.  This is one of the grants that I am most proud of. It is usually very hard to get different companies to work together on a project like this, but these 3 companies were eager and willing to work together to speed up the search for the cure!

  109. [06/04/2015] Blaze Bioscience Announces Open Enrollment for Phase 1 Clinical Trial of Tumor Paint BLZ-100 in Children with Brain Cancer  Exciting new technology for brain tumor surgery!

  110. [05/26/2015] Risk of surgical site infection in 401 consecutive patients with glioblastoma with and without carmustine wafer implantation  When Gliadel was first approved, there were rumors that it caused brain infections. There were reports that it happened much more frequently with inexperianced neurosurgeons, but not with the experienced  ones.  This article shows that there is no link between the wafers and infections. The long term data with Gliadel looks good. It is surprising that it isn't used more often.

  111. [05/15/2015] Tocagen Presents Updated Interim Survival Data from Ongoing Clinical Studies  Excellent news. This treatment is very elegant. They inject a virus into the tumor - in 1 of 3 different ways - this virus can only infect cancer cells (see tocagen.com for how that works). When it infects them, it inserts a gene that encodes for an enzyme which converts a nontoxic oral fungus medication into a powerful chemotherapy - only in the cancer cells theoretically leaving normal cells alone. They let the virus spread for a month or so, then give the oral medication.  This kills the cancer cells that have enough copies of the gene.  The cells that were infected but did not get enough copies of the gene acts as a reservoir to start the cycle again.  They wait another month and repeat the oral medications.   If that sounds scary, they did build in a safeguard. They designed the virus to be very sensitive to oral anti-viral drugs so that if something bad did happen (and it hasn't yet), they can give a drug and clear the virus from your system in about a day. Also the virus can't live in normal healthy cells.   The Musella Foundation has funded a small part of these studies.

  112. [05/15/2015] The Impact of Surgery on the Efficacy of Adjuvant Therapy in Glioblastoma Multiforme  This shows a major difference in outcome between GBM patients who had "radical" surgery vs. thos who did not.  They used a criteria of 1.5cm in diameter of residual tumor as the cutoff from radical to non radical surgery.  They did not go into detail on outcomes from patients with total resections but it looks like extent of surgery - even on a rough look like this - makes more of a difference than anything else.  This goes to show that selecting the right neurosurgeon and medical center - with the most experiance and the best tools, is the most important decision you can make.

  113. [05/11/2015] ZIOPHARM Announces Initiation of Phase 1 Study of Ad-RTS-IL-12 Gene Therapy in Patients With Brain Cancer  Another gene therapy trial is starting up for recurrent GBM and Anaplastic Astrocytoma.  I love the concept and will be watching this one.

  114. [05/11/2015] Novogen up 13% premarket on positive brain cancer study results Sounds promising. It hasn't been tried in humans yet but the key here is that it preferentially kills tumor cells over normal brain cells, at least in the test tube.

  115. [04/20/2015] Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer  (Disclaimer: I am on the  advisory board of the Brain Tumor Biotech Center at the Feinstein Institute).  The new brain tumor biotech center at the Feinstein Institute on Long Island, NY is designed to speed up the process of pre-clinical and clinical studies of new treatments for brain tumors, and to do it at a lower cost than traditional methods!  I would love to see more of these partnerships!

  116. [04/14/2015] Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response.  Metformin is a cheap, easily available drug used to treat type 2 diabetes.  Sounds interesting.

  117. [04/14/2015] Brain surgeon Dr. Andrew Parsa dies at 48  I am shocked by the news. Dr Parsa was one of the brightest stars in the brain tumor world. I was just talking to him at a conference recently about his vaccine work - he was so excited that his vaccine was going to have a big impact on the fight against brain cancer.  He came so far and unfortunately won't be able to see the impact he made on the field.  My condolences to the family.

  118. [04/10/2015] Observational, retrospective study of the effectiveness of 5-aminolevulinic acid in malignant glioma surgery in Spain (The VISIONA study).  5-aminolevulinic acid (also known as Gliolan) is a simple dye that is given before surgery that makes the tumor visible during surgery. It has been approved for years in Europe but not in the USA yet. This study shows that there is a better chance of removing the entire tumor and patients live longer when using it.  Doesn't make sense that it is not available in the USA.

  119. [03/15/2015] Y Combinator backs cancer drug combo testing service Notable labs was created by a friend of mine. They have a great concept: they grow a patient's tumor in the lab and try thousands of combinations of existing drugs on it to pinpoint the best combination to try.  They will be starting a clinical trial of it soon to prove the concept works.  Good luck to them!

  120. [03/15/2015] Long Island, NY SUPPORT GROUP MEETING FOR BRAIN TUMOR PATIENTS, FAMILY MEMBERS, AND CAREGIVERS  There is a new support group on Long Island.

  121. [03/14/2015] Phase 2 trial of dasatinib in target-selected patients with recurrent glioblastoma (RTOG 0627).  I had high hopes for this trial.  Previous trials that used targeted drugs against 1 target failed, so the thinking was to try targeting multiple targets. Dasatinib is active against 4 targets, and did not work.  Hopefully the concept is  correct and this mix of targets was wrong.

  122. [03/11/2015] Study: Tetanus Shot May Aid Treatment of Deadly Brain Cancer  Great results.  Of course it is too small to prove it works but it looks like it has no side effects and may have a huge benefit.   Hope the larger trial opens soon.  Perhaps the tetanus vaccine could help boost the other vaccines in trial now also. There will be a segment on cbs evening news tonight about it

  123. [03/07/2015] IBTA e-News From our friends at the IBTA 

  124. [03/06/2015] How A Group Of Lung Cancer Survivors Got Doctors To Listen

    The NCCN guidelines define the standard of care in the USA. Insurance companies- including Medicare - use the guidelines to deny claims for treatments that are not given a good rating by the guidelines. We have that problem with Optune (which used to be called the Novocure Novo-TTF100a system and the NCCN refers to as 'alternating electric field therapy').  The NCCN guidelines for GBM originally gave this treatment a fairly good rating - at least as good as many other treatments in use. This was reasonable, as the large trial for recurrent GBM  directly compared tumor treating fields to all of these other treatments and did at least as well or better. Then at the last update, the NCCN unexpectedly  lowered the rating to the worst category - even though all of the research articles that came out from the time they first listed it until this update were all very positive - not one negative report.  Just at that time, I met with Medicare to discuss coverage of this treatment, and they pointed out that the NCCN lowered the rating and used that as an excuse not to approve payment.

     

      Since that time, the groundbreaking results of the large phase 3 trial for newly diagnosed GBM patients came out with a 50% increase in the 2 year survival rate compared to standard therapy.  The FDA halted the trial because it actually was working and at that point said it was unethical to withhold the treatment from the control group.   This was the largest increase in survival since we started using radiation a LONG time ago. Much better than any of the other treatments the NCCN have given a higher rating than Optune.

     

    I wrote a letter to the NCCN requesting they reconsider the rating for Optune, giving them this new data. They had a meeting to consider it and we are waiting for the results. IF they did not raise Optune to the highest rating, I think it is time for us to fight it as this group of lung cancer patient in the attached article did:  a massive letter writing campaign to the NCCN, as well as to each of the doctors who make up the committee.

       

    BTW: While this fight is going on, the company that makes Optune has been excellent about giving easy access to this treatment to patients.  I do not know if that will continue if we lose this battle.    

  125. [02/26/2015] New clinical trial for Glioblastoma using immunotherapy  This is an exciting new trial for gbm patients either at first recurrence or if there is residual tumor after the initial surgery and radiation. Patients must be EGFRviii positive.  This type of treatment has shown fantastic results in other types of cancers and they are now trying it for GBM patients.

  126. [02/26/2015] Israeli Company Develops Device to Fight Tumor Growth with Electric Fields  (Disclosure: Novocure is a sponsor of our organization) We have talked a lot about this recently - I include this article because it points out that 2,000 patients have used it for gbms.  That is a lot of experience. It also says that tumor treating fields are now being tried on ovarian and pancreatic cancer.

  127. [02/09/2015] Dr. Howard Fine Named Founding Director of the Brain Tumor Center at NewYork-Presbyterian Hospital/Weill Cornell Medical Center  I mentioned this in the last news blast, but here is the official press release with more details!

  128. [01/31/2015] Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis.  The results for Gliadel wafer are impressive when you consider it is just a 1 time insertion of wafers. These wafers have been vastly underutilized at some brain tumor centers. The reason stated is usually that they would prevent you from entering some clinical trials but if you look at the history of clinical trials in the past, most did not result in a gain as good as Gliadel would have given.  The restriction on prior use of Gliadel wafer for clinical trials should be removed immediately. It is not ethical to withhold a known benefit. At the very least, it should be required to at least discuss the risks and benefits of Gliadel before any brain tumor surgery.

  129. [01/31/2015] One Dose, Then Surgery: A New Way to Test Brain Tumor Drugs  I love the concept. Just wonder if 1 dose of the drug is enough to tell. Maybe they should do a few days first.

  130. [01/22/2015] IBTA e-news  From our friends at the IBTA

  131. [01/20/2015] CytRx Announces Positive Interim Phase 2 Aldoxorubicin Results in Glioblastoma Multiforme (Brain Cancer)  Sounds very promising. It is rare to get a complete response in recurrent gbm

  132. [12/29/2014] FDA approves Opdivo for advanced melanoma  This is great news!  This drug is in clinical trials for GBMs. We do not yet know if it works or not, but if the GBM trial shows good results, it can be used off label immediately.  This is another reason EVERYONE here should participate in our brain tumor virtual trial.  This is a registry of brain tumor patients, the treatments they take and the outcome. IF we had enough people participating, we would already know the answer of if it helps for GBMs, and people would be able to use it now. For details and to join, go to virtualtrials.com and click on Virtual trial  

  133. [12/21/2014] Neuro-oncologists discover cancer cells can burn acetate for fuel I love projects like this - those that challenge the current thinking. It may open up a ne target not only for treatments but for diagostics.

     

  134. [12/17/2014] Novogen Announces Breakthrough Discovery in the Treatment of Melanoma    Sounds like an interesting drug for brain tumors but it also looks like this company doesn'[t have the resources to develop it. Hopefully another company will come along and partner with them to develop the brain tumor version.

  135. [11/20/2014] Cancer patient’s desperate plea for NHS to fund vital drug  It's a shame that the brain tumor patients have to not only fight a terrible disease but have to worry about the expenses involved..   We are having a similiar problem here in the USA with the new treatments.

  136. [11/19/2014] Al Musella`s Brain Tumor Blog on SNO2014  This is my thoughts on the exciting news from SNO this week!

  137. [10/23/2014] Brain barrier opened for first time to treat cancer  Interesting new way to open the blood brain barrier.

  138. [10/22/2014] Neural stem cells: On the frontier of brain cancer therapy  This is a fascinating new clinical trial for recurrent high grade gliomas.  The neural stem cells migrate to the tumor cells, and carry an enzyme that converts a harmless oral anti-fungal drug into a toxic chemotherapy drug only in the local area where tumor cells are.  Hopefully this will result in the cancer cells getting killed and minimizing side effects to the noraml cells.  It is a phase 1 trial so there are no results to look at yet, but it is worth thinking about this trial. Click HERE for details on the trial

  139. [09/28/2014] Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma  This is an interesting trial design - hey tested every combination of temodar and 3 add on drugs... there probably wasn't enough patients to be sure but early result look like adding isotretinoin  (Accutane) actually did worse than temodar alone, and none of the combinations did much better than temodar alone. The best was all 3 drugs plus temodar, but not by much over temodar alone.  

  140. [09/04/2014] A one-two punch for brain tumors? New clinical trial opens at U-M  Sounds like an interesting approach

  141. [08/31/2014] Atlantic NeuroSurgical Specialists (ANS) Introduce Noninvasive Treatment for Brain Tumor Patients  There are a lot of new doctors who are certified in the use of this FDA approved treatment for recurrent GBMs.. go to www.novottftherapy.com/ and put in your zip code near the top right of the page to find one near you.

  142. [08/23/2014] Clinical trial offers promising results for brain cancer patients  There is a video about this procedure at http://virtualtrials.com/video2012.cfm?video=201202  

  143. [08/23/2014] Phase II trial of sunitinib for recurrent and progressive atypical and anaplastic meningioma  Sunitinib is an oral targeted therapy approved  to treat cancer of the stomach and pancreas, so it is easily available.  The 6 month progression free survival rate was 42%, which is much better than anything I have seen for this type of tumor.  The overall survival rates are still not good enough but perhaps this may become another tool to use as part of a comprehensive treatment plan that does much better.

  144. [08/17/2014] A novel, reproducible, and objective method for volumetric magnetic resonance imaging assessment of enhancing glioblastoma.  This is one of the most important articles of the year. One of the main problems that slows down drug development for GBMs is the inability to agree on tumor response or progression.  If this method is proven to work, it can drastically speed up the search for the cure.

  145. [08/17/2014] The Effect of Timing of Radiotherapy in Patients with Newly-Diagnosed Glioblastoma Multiforme Receiving Temozolomide: An Analysis Based on the University of California, San Francisco Experience.  This study suggests that starting radiation 30-34 days after surgery may be better than starting sooner - or later than 35 days..  However, they did not correlate it with WHY some patients waited 30-34 days, others waited over 34 days and yet others had radiation sooner.  That might account for the differences.  To test this correctly, patients should be randomized to start radiation at the standard time or at 32 days and see if there is a difference.

  146. [08/04/2014] Novocure Announces Commercial Launch of NovoTTF™ Therapy in Europe and Israel The Novocure system is now available in Europe and Israel!  

  147. [08/03/2014] Congressman recovers from brain tumor surgery  I usually do not post stories like this but perhaps this congressman can become an ally  in our fight to get a new law to make all major brain tumor centers considered as "in network" on insurance plans. This senator chose 2 of the best hospitals in the country to get treatment for his tumor. Why is it fair that the average person isn't allowed that same opportunity?

  148. [07/23/2014] Physicians at 15 leading brain cancer centers in 8 countries certified to provide NovoTTF Therapy to recurrent glioblastoma patients on prescription order  The Novocure system is now available in 8 other countries (beside the USA where it was FDA approved a few years ago)!

  149. [07/23/2014] Parents fight insurance company to keep baby`s cancer surgery docs

    This issue is becoming a huge problem.  Insurance companies – especially the Obama Care Health Exchanges – are limiting your choice of doctor and hospital. I do not know how they have the right to do that. It doesn’t seem fair or even useful.   I am working with the National Brain Tumor Society to try to get a new law passed that would include all NCI designated cancer centers as “in network” for all insurance plans.   That would be a good start. Eventually, we should do away with “in network” panels.  Health care is too important to allow a bureaucrat to make the decisions for you on which hospitals or doctors to use.   My solution would be to do away with network panels all together. Instead, the insurance company can publish a fee schedule that they would pay to any doctor treating the members.  They publish a list of doctors who would accept that fee schedule (plus copayments and deductible) as payment in full.  This way you can select any doctor you want and the insurance will pay the fee schedule amount. If the doctor you select is on the list, you just pay the copayment and deductible.  IF the doctor you select isn’t on the list, you also pay the difference between the regular fee and the fee schedule amount.

  150. [07/04/2014] Agenus Brain Cancer Vaccine Shows Extended Survival in Phase 2 Final Data Analysis Good results.  I like the idea of adding the checkpoint inhibitor to increase the effect of the vaccine.

  151. [06/19/2014] Itraconazole suppresses the growth of glioblastoma through induction of autophagy: Involvement of abnormal cholesterol trafficking.  Itraconazole is an antifungal drug used to treat fungal toenails and other fungal infections.  It is very safe with minimal side effects.  It has been tested for use in other cancers. A recent study http://med.stanford.edu/news/all-news/2014/02/oral-anti-fungal-drug-can-treat-skin-cancer-in-patients-study-shows.html showed that it can reduce the size of skin cancers.     

  152. [06/19/2014] Progesterone could become tool versus brain cancer  Interesting, but I caution that we need to see the research before trying it. They say a low dose can make the tumor grow faster while a hig dose inhibits growth... so we need to see exactly what doses are needed... as well as the effect of p53 mutations

  153. [06/16/2014] ImmunoCellular Therapeutics Presents Updated ICT-107 Phase II Data in Patients with Newly Diagnosed Glioblastoma at the 2014 ASCO Annual Meeting  Pretty impressive results. The most important number is that currently 21% of the treated patients are alive compared with only 7% of the control group.  This is for a simple series of shots in the arm with minimal or no side effects.

  154. [06/08/2014] U.S. to test immunotherapy drugs on newly diagnosed brain tumors  This is one of my favorite new trials.  It worked pretty good with melanomas. Let's hope it works with GBMs.

  155. [05/25/2014] The role of laser interstitial thermal therapy in enhancing progression-free survival of difficult-to-access high-grade gliomas: a multicenter study.  This was not a controlled trial, but the results look pretty good. They use a special laser to kill brain tumors that are not easily operable and the results are similiar to removing the entire tumor.

  156. [05/21/2014] The Electric Anticancer Helmet Battles Brain Tumors   Popular mechanics picked up on the story of the Novocure system.  They made a mistake in how it works.. they say "NovoTTF blasts tumors with alternating electric currents "  when it should be alternating electric FIELDS. 

  157. [05/15/2014] A novel implantable catheter system with transcutaneous port for intermittent convection-enhanced delivery of carboplatin for recurrent glioblastoma.  This may be a new way to deliver treatments into the brain over long periods of time.

  158. [05/04/2014] Human fat can help treat brain cancer  Interesting - will be watching this as they apply it to people.

  159. [04/27/2014] Aquaporin-4 in glioma and metastatic tissues harboring 5-aminolevulinic acid-induced porphyrin fluorescence.  This may show how Gliolan works. It is a dye that makes the tumor light up during surgery - approved in Europe but not the USA.  

  160. [04/23/2014] Glioblastoma Vaccine Hits Primary Endpoints in Phase 1 This phase 1 trial did better than expected (but that is only with the endpoint of safety and immune response, they did not mention survival in the article).  Sounds like a great concept. They have an approach similiar to ICT-107 but with different  targets. We will be keeping  an eye on this one!

  161. [04/23/2014] Glioblastoma stem cells: a new target for metformin and arsenic trioxide.  Sounds interesting in theory - but a clinical trial is needed to test it. Should be easy because both components are fda approved for other things. Keep in mind arsenic at the wrong dose can be fatal.

  162. [04/12/2014] Interim Clinical Data for Tocagen`s Toca 511 & Toca FC in Patients with High Grade Glioma  Good news on the Tocagen Trial.   Safe, well tolerated and early results are better than historical controls. This is one of my favorites. Disclaimer:  Tocagen is a small sponsor of our organization, and we are a small sponsor of their clinical trials!

  163. [04/09/2014] Fractionated stereotactic radiosurgery with concurrent temozolomide chemotherapy for locally recurrent glioblastoma multiforme: a prospective cohort study.  I am a fan of fractionated stereotactic radiosurgery for GBMs. My sister in law participated in an earlier trial using FSR and a different chemotherapy drug and did very well for about 8 years. She did better than most in that trial but perhaps temodar is a better drug to use along with FSR. 

  164. [04/08/2014] Integrin Inhibitor Suppresses Bevacizumab-Induced Glioma Invasion.  When I first heard about the drug Cilengitide, I thought it would be perfect to use with a treatment like Avastin.  I hope to see human trials of this soon.  My thoughts:  as shown in this article, Avastin cuts off the blood supply to the tumor, and stops a new blood supply from forming, so the only way the tumor can survive is to invade surrounding areas looking for a new blood supply.  It makes sense to combine it with a drug that stops that invasion.

  165. [03/27/2014] Inhibitory Effect of Disulfiram/Copper Complex on Non-small Cell Lung Cancer Cells.  Although this project was not done for brain tumor cells, it illustrates a very important concept.  I hear of some of our members trying Disulfiram off label to treat their tumors.   There was also a project a while back that tested a copper restriction as a treatment for brain tumors.  So some members combined both.  However this study points out that in lung cancer cells (we do not know if it is true for brain), copper is needed to make the Disulfiram work.   This points to the need to track people who try these combinations..  this is WHY we run the brain tumor virtual trial. Go to virtualtrials.com and click on Virtual trial for details and to join.  Everyone who has a brain tumor should participate.

  166. [03/18/2014] First Patient Enrolled in GenSpera G-202 Phase II Glioblastoma Trial  Sounds like an interesting trial.

  167. [03/16/2014] Doctors decode chemo resistance in childhood brain tumour, find potential drug They may have found a better treatment for ependymomas in kids.  I usually say it is too early, since they didn't do the clinical trials yet, but when you have no other treatment, this may make sense. It is a drug approved for a different type of cancer so is easy to get.

  168. [03/13/2014] Deferred use of bevacizumab for recurrent glioblastoma is not associated with diminished efficacy We still do not know the best way to use Avastin. This articles seems to say that it doesn't matter when you start it - at the start, after first, second or third recurrence.  It still gives about the same effect.

  169. [03/12/2014] http://phys.org/wire-news/156012592/aacr-recognizes-contributions-of-multi-institutional-research-te.html  It's nice to see these top researchers to get the recognition they deserve!  

  170. [03/11/2014] Tocagen Doses First Patient Intravenously in Clinical Trial of Selective Cancer Therapy, Toca 511 & Toca FC  The Toca 511 trial has been one of my favorites. It is a new type of gene therapy where a virus that only grows in tumor cells delivers a gene that can convert an oral  nontoxic antifungal drug into a powerful chemotherapy, only in the cancer cells that were infected by the virus.  There are now 3 separate clinical trials going on for the Tocagen treatment.  The original 2 used local delivery of the virus to the area of the tumor. This one adds an IV injection of the virus and also local delivery. The idea is that it may be better able to hit those tumor cells that are spread out in the brain, far from where the MRI says the tumor is. The Musella Foundation is one of the sponsors!

  171. [03/11/2014] Exclusive: Germany OKs Northwest Bio brain cancer drug, shares soar  Great news!  DC-Vax can now be sold in Germany.  I do not know yet if Americans can go get it and bring it back. If anyone tries, please let me know how it goes.

  172. [03/06/2014] Cellectar begins phase II imaging trial of I-124-CLR1404 in patients with glioblastoma    This trial is trying to find a better way to see the true extent of the tumor.  There is a great need for better imaging - a regular MRI is not really good enough - many times an MRI may say progression where there isn't progression or shrinkage when there really is progression. 

  173. [02/28/2014] Tiny Northwest Biotherapeutics aims to dominate brain cancer  Nice story about DC-Vax and how 1 person can make a huge difference. Without Linda Powers, the trials would have ended

  174. [02/13/2014] IBTA Newsletter From our good friends at the IBTA 

  175. [01/28/2014] Phase II clinical study on intraoperative photodynamic therapy with talaporfin sodium and semiconductor laser in patients with malignant brain tumors.    Amazing results with such a seeminly easy procedure... but of course the standard warnings apply - it is a small group of patients and they only follow them for the first year. But interesting to watch

  176. [12/24/2013] Blaze Bioscience Announces Initiation of First-in-Human Phase 1 Clinical Study of BLZ-100 Tumor PaintTM technology enters clinical stage of development  This one is for skin cancer only, but the technology was invented to help surgeons see where brain tumors are - to tell the difference between normal and cacnerous.  We are trying to help raise the money needed to get a brain tumor trial going - hopefully pediatric brain tumor!  That is where it is needed most.

  177. [12/18/2013] Positive Phase 2 Results from Agenus` Brain Cancer Vaccine Published in Neuro-Oncology  Pretty good news on a vaccine trial....  there was no control group but it beat historical controls. Survival (I assume after recurrence) was 11 months for the vaccine, compared to 3 to 9 months for historical controls.  

  178. [12/04/2013] Patients having brain cancer can improve their cognitive function by a new surgical approach  Whole brain radiation is not usually used for GBMs now (unless they already spread throughout the brain), but has been the standard for cancers that spread to the brain. This article suggests that delaying radiation may lead to less loss of cognitive functioning.  They used Gliadel wafer or stereotactic radiosurgery to slow down the recurrences.

  179. [11/25/2013] Update: 50 Percent of Patients in Cedars-Sinai Brain Cancer Study Alive After Five Years This was presented at the Society of Neuoroncology meeting last week.  Exciting news. Using a vaccine that had no significant side effects - and doesn't even require a tumor sample, 1/2 of the patients alive at the 5 year point, and 7 out of 16 still alive 5 to 7 years after treatment.  This was from the original phase 1 trial. They completed a phase 2/3 trial last year and are just waiting to see the outcome. Hopefully they will present the results of that trial soon.

  180. [11/19/2013] Tumor Paint: Changing the way surgeons fight cancer  One of my favorite doctors.. nice story

  181. [11/13/2013] Study Results Show Dose-Intensified Temozolomide Chemotherapy in the Adjuvant Setting Does Not Improve Survival in Patients with GBM  Apparently. the standard schedule is better than the dose intensive schedule for GBM patients using Temodar.  However, what I would love to see is a trial comparing different lengths of treatment. This trial used up to 12 months of treatment.  Overall survivals were about 6 months after they stopped using the Temodar in either arm.  Doesn't make sense to me to stop at 1 year.

  182. [09/14/2013] Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma.  This article shows that - in the lab - a common food additive that has been deemed "safe" by the FDA may have anti tumor properties and in the test tube may help Temodar work better. Of course, this isn't in humans so we do not know yet if it would help people, but I love the idea of using a readily available, cheap, nontoxic to increase the chances that Temodar would help..  

  183. [09/06/2013] Pairing cancer treatments shows patient improvement This is for low grade tumors - shows that what worked for high grade tumors - combining Temodar with Radiation, also helps low grade brain tumors

  184. [09/06/2013] Survival in Patients with Glioblastoma Receiving Valganciclovir  Very Important Article.  First the warnings:  1. this is a small study, funded in part by the company that makes the drug. 2. It was not randomized, and there was no control group - they compare to historical cotnrols..  3. We have seen other treatments do very well in small, selected patients then not do well in large controlled trials. Having said that, these results are outstanding, doubling the average survival time by using a simple, easily available  (but expensive)  anti-viral pill.   It is probably too soon to say we should try it but I would say it definately needs another trial, and I wouldn't hesitate to enter the trial if I had a gbm.  For more background, read the articles on virtualtrials.com on this concept: Click HERE and here and HERE

  185. [09/03/2013] Testing of vaccine for brain cancer -Nassau County, NY  I mentioned this a few weeks ago but this article adds a short video about the vaccine.

  186. [08/26/2013] Lighting up brain tumors This is one of my pet peeves about the USA FDA.  This treatment can help surgeons remove more of the tumor safely, and it is approved in Europe, used on thousands of patients safely. The FDA refuses to allow it's use here because they admit it is effective in allowing more of the tumor to be removed safely, but they question if that is a benefit.    They want a large randomized trial to be done comparing overall survival with patients who use this vs those who use a placebo.  I know that is one trial I would not be referring patients to. It is unethical and unnecessary.      I love the FDA - they understood the need to approve Avastin and the Novocure system even when they only showed a small benefit.  Now that they are approved and being used in combinations - they are showing better progress.   It is just in cases like this where FDA policy goes against common sense.  

     

  187. [08/26/2013] Researchers start clinical trials on neutron beams to treat cancer  Boron neutron capture therapy is an old treatment consisting of giving the patient a boron containing drug which concentrates in the tumor, and then shooting neutron beams at it. The neutron beams do not hurt the cells that do not have boron - but in the cells that did take up boron, the neutrons split the boron releasing radioactive particles that kill the cell. This has been tried before but the problem was fiding a way to get the boron into all of the tumor cells.  Years ago we did not have that technology, but now we are much closer!  Worth trying again.  

  188. [08/05/2013] ImmunoCellular Therapeutics Announces Initiation of Phase I Trial of Cancer Vaccine ICT-121 in Recurrent Glioblastoma  Interesting trial.. worth looking into for recurrent gbm

  189. [08/02/2013] Brain Tumor Center to Study Vaccine
    North Shore center to study glioblastoma patients.

    Dr Schulder is on our medical advisory board and one of my favorite brain tumor neurosurgeons..   he is doing a trial of rindopepimut (which used to be known as cdx-110). This is a vaccine against the Epidermal Growth Factor Receptor version 3(EGFRvIII) , which is a mutation of the EGFR which is found on normal cells. (The article is wrong on that point).  If EGFRvIII is found on your tumor, it is a bad sign - the tumor is of the more aggressive variety because this receptor makes the tumor grow faster. This vaccine inactivates the EGFRvIII.  The hope is that it can stop the tumor from growing, or even if it fails, it might be able to convert the tumor into a slower growing tumor with a better prognosis.

    Best part is that it is relatively easy injections into the skin - not into the brain.

    (Disclosure:  the company that makes rindopepimut  is a sponsor of our foundation, and Dr Schulder is on our medical advisory board)



  190. [07/08/2013] New EU-Funded Consortium to Develop Fully Personalized Cancer Vaccines for Brain Cancer Patients  New concept in vaccine therapies.  The vaccine is custom made to each patient, based on a genetic profiling of your tumor.  The Musella Foundation and Voices Against Brain Cancer also have helped fund this!

  191. [07/03/2013] Dr. Gregory Foltz, who founded brain-cancer clinic, dies at 50  We lost one of the best brain tumor researchers in his prime.  So sad. Very nice man - brilliant, compassionate and driven to find the cure of gbms for us.  He will not be forgotten. His work lives on - it would be fitting if his program leads to the cure.

  192. [07/02/2013] National Cancer Institute Designated Cancer Center Featured Article: ‘Promising Target’ Found in Treating Deadly Brain Cancer at UVA  Interesting new target -  but it is a few years away from human trials.

  193. [06/30/2013] Circulating microparticles of glial origin and tissue factor bearing in high-grade glioma: a potential prothrombotic role.  We always knew GBM patients had a higher chance of developing blood clots in the legs and lungs... but never knew why.  This article may have the answer.

  194. [06/29/2013] IBTA Newsletter  From our friends at the IBTA

  195. [06/14/2013] Mechanisms of evasive resistance to anti-VEGF therapy in glioblastoma.  This sounds like one of the most promising avenues of research... find out why Avastin stops working and how to turn that around.  I feel that the answer to this question may lead to a major breakthrough, hopefully using drugs that are already available so it can be used by all who need it quickly.

  196. [06/14/2013] Advancing Neuroscience: MRI Interventions, IMRIS and Tocagen Combine Technologies to Precisely Deliver Potential Cancer-Fighting Drug to Brain Tumors  This is one of my favorite experimental treatments... and it looks like they may have found a better way t deliver it to where it is needed.

  197. [06/11/2013] Disseminated progression of glioblastoma after treatment with bevacizumab.  Avastin has gotten a lot of bad press recently. Here is some good news about Avastin from UCSF - one of the best brain tumor centers in the world!   There have been reports that Avastin causes the tumor to become more invasive. The thinking is that it works by stopping the tumor from forming new blood vessels, which are needed for the tumor to grow. However, when you cut off the blood supply to the tumor, you would think it makes sense that the tumor cells migrate and look for a new blood supply. There have been some reports that Avastin makes the tumor more invasive.  This report says that is not true.

  198. [06/02/2013] Cyto-megalovirus might speed brain-cancer growth  We had known about a link between cyto-megalovirus (CMV)  and GBMs for a few years. This article gives an explanation of how the virus may activate a pathway that drives tumor growth.  There is a drug available against the CMV - and it is in trials now in Europe.  There is also a vaccine against this virus in trials. This opens the door not only for a treatment but the possibility of using a CMV vaccine to prevent the development of cancer (not only brain tumors)!

  199. [06/01/2013] Genentech Announces Final Phase III Study Results of Avastin Plus Radiotherapy and Chemotherapy in People with an Aggressive Form of Brain Cancer This trial looked at a large number of newly diagnosed GBM patients.  1/2 received the standard treatment of Surgery, Radiation and Temodar during radiation and for 6 months afterwards, or that same treatment + Avastin until recurrence.  Temodar was stopped after 6 cycles in both groups.  The results weren't as good as we were hoping for but they are a small step foward. They reported no difference in median overall survival, but there was a big increase in progression free survival in the Avastin group ( 8.4 months vs. 4.3 months), as well as the % of patients alive at the 1 and 2 year points.  "Seventy-two percent of people treated in the Avastin arm were alive at one year compared to 66 percent of people in the placebo arm (p=0.049). Thirty-four percent were alive at two years compared to 30 percent, respectively (p=0.235)."   In human terms this means that although on average both groups lived about the same length of time, the Avastin group was in better shape for most of that time.  This is very important. And more of the patients in the Avastin group went on to do much better than the ones in standard of care group.    So it looks like Avastin should play a role in the treatment of GBM but the question now become what is the best way to use it? For newly diagnosed or at recurrence? (It is already approved for recurrent GBM). Or perhaps in combination with other treatments. More research is needed.  We (The Musella Foundation) has been funding exciting research looking at ways to make Avastin work better. Hopefully we can figure out why it helps some patients and not others, then make it work for all.   (Disclosure: Genetech - the makers of Avastin - is one of our sponsors)  

  200. [05/26/2013] Cold plasma successful against brain cancer cells  Exciting research on a new way to treat brain tumors.  It is still only in the lab but this is a completely different treatment method. Cold Plasma is a gas that has been used to sterilize foods. It has now been found to have a strong effect on cancer cells.  It is too early to try it on people, but this is something to keep an eye on

  201. [05/26/2013] Restoration of Sensitivity in Chemo - Resistant Glioma Cells by Cold Atmospheric Plasma. [Full Text]  This is the full text of the technical article on Cold Atmospheric Plasma.  See previous article for layman's version!

  202. [05/02/2013] Top Neurosurgeons from Long Island Brain Tumor Center Offer New Treatment for Recurrent Glioblastoma  Another new center that offers the Novocure system!

  203. [04/28/2013] Oregon Neurosurgeon Dr. Jefferson Chen Uses New Approach for Treatment of Brain Tumors and Blood Clots  This is a new set of tools which may help the neurosurgeon remove more of the tumor with less damage.

  204. [04/19/2013] NW Bio Announces That Another Brain Cancer Patient From Phase I/II DCVax(R)-L Trials Has Surpassed Ten-Year Cancer-Free Survival Amazing story... Having 1 ten year survivor could be a fluke.. but 2 ten year survivors is very impressive.

  205. [04/17/2013] The impact of improved treatment strategies on overall survival in glioblastoma patients.  This is one of the most important articles of the year. First, it shows that adding Temodar at the same time as radiation will double overall survival times compared to using radiation without Temodar.. We already knew that but it is nice to see it confirmed. The new part is that using a dye called 5-ALA at the time of surgery (that allows the surgeon to see where the tumor is)  adds another 3.5 months to the average survival time.. and in those cases where it allows for a complete resection, it adds another 11 months.    This dye is approved in Europe and used as a standard treatment for years.  Getting it approved here in the USA would be a big step foward.  3.5 months might not seem like much, but it can buy the time for other treatments to work.    

  206. [04/08/2013] Feds to cut Medicare payments for cancer-fighting Gamma Knife, thanks to Congress   This is an interesting situation.  The companies that make competing radiosurgery tools somehow managed to first get Medicare to pay double for one tool, then the other manufature managed to get them to reverse the decsion and pay the same fo the procedure no matter which tool is used.   I do not know how much these things cost - but I would hate to see us lose access to one of the tools due to these cuts. On the other hand, I always felt there should be no economic incentive for a doctor to use one tool over the other. Ideally the decision should be based on what is better for the patient than how much they will earn for using one over the other.

  207. [03/26/2013] IFRT offers viable alternative to WBRT Whole brain radiation is traditionally used when someone has a metastatic brain tumor. This article shows a small study which shows a limited field may be just as useful, with less side effects. This is not  controlled trial where they randomized 1/2 of the patients to involved field radiation and compared them to the half who got whole brain, so although it looks encouraging, so I would love to see others repeat it to make sure it is valid.  But it is something to consider.

  208. [03/24/2013] Treatment outcome and prognostic factors of adult glioblastoma multiforme. This article talks about the outcomes for GBM patients treated with the standard treatments  in Iran. Average progression free survival was 6 months and average survival was 11 months. Only 7% of patients had a complete resection.  Here in the USA,  a much higher % of patients get complete resections, and the average survival with standard treatments is over 18 months.  There are some small trials that reported overall survivals of 38 months. This points out the need not only for us to find the best treatments but to make sure they get out to the rest of the world.  WIth the latest treatments being so expensive, that might not happen for a long time or ever.  Something has to be done about that. I have no idea how to approach it.  Any ideas?  

  209. [02/16/2013] Cancer patients feel less distress after massage therapy, study finds  Obviously, everyone likes massages, but this study shows that it can significantly help brain tumors patients psychologically as well as making them fel better.  Worth a try!  

  210. [02/14/2013] Effects of valganciclovir as an add-on therapy in patients with cytomegalovirus-positive glioblastoma: A randomised, double-blind, hypothesis-generating study.  In the last news blast, I talked about using the anti-viral (anti CMV) Valcyte for GBMs.  Today I came across a report on a trial for Valcyte with standard therapy for GBMS.  This was a randomized trial - half get standard treatment and half get Valcyte for 6 months  in addition to standard treatment. The trial allowed patients to stay on Valcyte after the 6 months if they wanted to and they allowed the control group to switch to Valcyte - which complicates the interpretation.. as patients who were doing well probably stayed on the valcyte while those doing poorly probably stopped... so take this as an indication that it might help - not proof..  There was a small difference on scans but a big difference on overall survival: OS at 4 years was 27.3% in patients who used Valcyte for over 6 motnhs versus 5.9% in controls (P = 0.0466).  

  211. [02/12/2013] Milestone Clinical Trial for DIPG Approved Interesting new trial for DIPG.  

  212. [02/02/2013] Correlation between contrast enhancement on intraoperative magnetic resonance imaging and histopathology in glioblastoma.  This article says that a gbm is not limited to the area of contrast enhancement.  I have been saying over and over that we need things like Gliagen - the dye that lets a surgeon see where the tumor is during the operation.  This article backs up the need.

  213. [01/27/2013] Surgery of high-grade gliomas guided by fluorescence: A retrospective study of 22 patients.  I know it seems obvious, but this study shows that removing more tumor helps people live longer.  The difference between a total resection and a sub total resection is 8 months in overall survival:  12 months vs 20 months.  This is with the simple addition of a dye that lets surgeons better visualize where the tumor is.   This dye (Gliolanis approved in Europe but the FDA in the USA is dragging it's feet in getting it approved for us. 

  214. [01/27/2013] Optimizing Glioblastoma Temozolomide Chemotherapy Employing Lentiviral-based Anti-MGMT shRNA Technology.   I love this type of thinking.  It is not in humans yet but I will watch this closely.  Basically, MGMT is a protien that can stop Temodar from working.  It actually repairs the damage to the DNA that Temodar causes. People with tumors that have low levels of MGMT do better than people with high levels. This project tries to block the MGMT from being created, so it should help people do better.

  215. [01/23/2013] NCCN Guidelines® Recommend NovoTTF™ Therapy as a Standard Treatment Option for CNS Cancers  Important announcement:  the standard of care for GBMs has just been changed to include the use of the Novocure device at recurrence.  For more details on the Novocure device, first view the video on our home page at virtualtrials.com then from the menu at the top of the page, click LEARN ABOUT then NOVOCURE.  We have many of the research papers that were published about it, as well as a link to the list of doctors who are certified to prescribe it!

  216. [12/30/2012] Musella Foundation For Brain Tumor Research & Information, Inc 2012 Highlights Highlights of our work over the year!  There is still time to make a tax deductible contribution for 2012!

  217. [12/30/2012] The Methodist Hospital and Remeditex LLC Work to Develop Brain Tumor Drug  Interesting new approach.. Too early - not in humans yet - but interesting idea!

  218. [12/27/2012] Electric field treatment takes aim at brain cancer Nice article about a man who is using the Novocure device. (Disclosure: The company that makes Novocure is one of our sponsors)

  219. [12/20/2012] Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin/Ran protein complex.  This is fascinating on 2 levels... first - they describe a protien complex Survivin-Ran  which may be responsible for making GBM cells resistent to Temodar, then they use a new method to create drugs using computer modeling - the start with the target  then engineer a drug on a computer that would attach to the protien complex - and then actually make the drug.  And in the test tube it actually works.  This is way too early to help us - but something to keep an eye on.

  220. [12/16/2012] Musella Foundation Grant Award to Tocagen - Interim Progress Report  Just a quick update to show how YOUR donations are being used!  

  221. [12/11/2012] IBTA E News December 2012  This is from our friends at the IBTA!

  222. [11/30/2012] Swedish Receives $2.5 Million Grant from the Ivy Foundation to Advance Brain Cancer Research  Major grant from the Ivy Foundation to one of my favorite brain tumor doctors.. Dr. Greg Foltz.   He was a speaker at one of our conferences.  You can see his lecture at: virtualtrials.com/VIDEO2010.cfm     He is working on finding drugs that are already FDA approved for other conditions that might also help brain tumors.  Great approach!

  223. [11/28/2012] `Tumor Paint` Research Of Pediatric Oncologist Jim Olson Featured In Short Film -- A Sundance Festival Semifinalist This is an amazing technology..  it allows the surgeon to see where the tumor is during surgery. This video shows why it is so important.    The video is in a contest. Winner gets $100,000 which will be used to help develop this tumor paint.  We need you to vote for it. To vote, go to: http://vimeo.com/focusforwardfilms/semifinalists  and click on the tumor pain video, then when viewing the video, click the VOTE icon on the middle right side of the video, then confirm it!   (Disclaimer: Dr Olson is a friend of mine:)

  224. [11/21/2012] Uninsured brain cancer patients may be more likely than insured to die after surgery to remove tumor They also found that medicaid patients do as well as patients with private insurance. Uninsured patients are twice as likely to die in the hospital.  They did not figure out why - but that has to be looked at.

  225. [11/19/2012] Genentech Study Showed That Avastin Helped People with Newly Diagnosed Glioblastoma Live Longer with  This was the big news at the Society of Neuro-oncology conference this weekend.  There was about a 50% improvement in progression free survival by adding Avastin to the standard treatment, over using the standard treatment alone.  This means that patients feel better and can take care of themeselves longer with Avastin than without.    However, the question remains when is the best time to use Avastin, right at the start or wait for recurrence. That question is not yet answered.   There seems to be (but hasn't been tested yet) about the same time benefit for using at it the time of recurrence rather than at the start.  (Although using it at the start allowed patients to functional at the highest level for a longer period of time. )  My own thoughts (and I am not an MD - so take it for what it is worth):  My preference would be to enter a clinical trial for newly diagnosed GBM patients and hold off on the Avastin until the time of recurrence. IF you can not enter a trial, then it is a toss-up on when the best time to start Avastin would be. Either way can be argued.  There are more trials (such as the Tocagen trial) that now allow you to enter after having had Avastin, so that removes one of the barriers to using Avastin upfront.   Disclosure: Genetech is a sponsor of the Musella Foundation

  226. [11/13/2012] IBTA E NEWS NOVEMBER 2012  This is the newsletter from our friends at the International Brain Tumor Association!

  227. [11/13/2012] Multiple resections for patients with glioblastoma: prolonging survival.  This study shows that having multiple surgeries for glioblastomas does improve average survival.  Seems obvious - but in the past some doctors would advise that a 3rd or 4th surgery is a waste of time. This shows that each surgery does extend survival by months.. those moneths can be used to try another treatment.. increasing your chances of beating the tumor.

  228. [11/13/2012] Avastin Reduces Brain Necrosis from Radiation  This is an exciting article.. it says that using Avastin in combination with stereotactic radiosurgery greatly reduces the chances of developing radiation necrosis from 50% to 3-6%, and almost doubles the average survival!   Disclaimer: Genetech - the makers of Avastin - are a sponsor of our organization! 

  229. [11/13/2012] Health News : Mayo Clinic in Arizona is the First in the Southwest to Offer New Treatment for Recurrent Glioblastoma Brain Tumors Although the Novocure NovoTTf-100a device is FDA approved for recurrent glibolastoma, it is not yet available everywhere.  Doctors have to become certified in it's use and the company needs to set up tech support centers in each area served.  For a list of centers that offer it now, go to: http://www.novottftherapy.com/   Disclaimer: Novocure is one of our sponsors!

  230. [10/11/2012] UC Irvine opens clinical trial of novel treatment for brain cancer   This is one of my favorite clincial trials (it is being done all over the USA) ... however, the problem is that you need to enter the trial BEFORE your first brain tumor surgery.  Most people do not hear about this until after it is too late  We need to spread word of options such as these.  My pet peeve is that most neurosurgeons will not discuss the fact that by doing the surgery you will be forever excluded from clinical trials that require you to join before the first surgery.   Something to think about if you are about to have that first surgery.

  231. [10/10/2012] Impact of extent of resection for recurrent glioblastoma on overall survival.  This articles says that at the second surgery for a GBM, getting a complete resection adds a few months to survival.  We already knew that was true for the initial surgery. This might not sound like much, but it may be enough added time for something else to work.

  232. [10/10/2012] Bevacizumab (Avastin) continuation beyond initial bevacizumab progression among recurrent glioblastoma patients.  Although better than the alternatives tested,  still not good enough and shows the huge need for more research.  They didn't include the Novocure NovoTTF-100A which is the only other approved treatment for recurrent GBMs and they did not include any of the exciting clinical trials.

  233. [09/29/2012] Model T muscle CARs can treat brain tumors. As I mentioned a few issues ago, the IL13Ra2 antigen is one of my favorite targets. I will be watching this.

  234. [09/22/2012] Extent of resection in patients with glioblastoma: limiting factors, perception of resectability, and effect on survival.

    This article shows that when the surgeon thinks he/she "removed the entire tumor", he is wrong about 70% of the time.   This shows the need for the approval of the dye that lets the surgeon tell where the tumor is when operating, and also for more hospitals to get intra-operative imaging tools like MRI or ultrasound that can help them tell where the tumor is.

    Note that in many cases it is not possible to remove all of the tumor – the risk of neurological damage is too high, but the surgeon should know exactly how much of the tumor is being left behind. These tools can help.

  235. [09/16/2012] The impact of repeated surgery and adjuvant therapy on survival for patients with recurrent glioblastoma.  This study shows that surgery alone for a recurrence of a GBM is not that useful: it adds on average 1 month to survival (compared to the group that had no treatments), and almost half of the patients had major complications from the surgery. However, combining surgery with chemotherapy gave the best outcome, adding 9 months on average - while chemo alone added only  3 months.   This is a small study and apparently wasn't randomized - so we don't know if perhaps people who were in better shape got to get both surgery and chemotherapy, and the patients who were in worse shape got no treatment - which would completely invalidate the results. However, it makes sense that combining the treatments would give the best outcome.  Perhaps adding more of the available treatments, like immunotherapy and tumor treating fields would yield even better results.

  236. [09/16/2012] Phase I/II study of oral erlotinib for treatment of relapsed/refractory glioblastoma multiforme and anaplastic astrocytoma.  Unfortunately, this trial shows that oral erlotinib (Tarceva) - an EGFR inhibitor - used by itself for recurrent gbms and anaplastic astrocytomas doesn't work well. Progression free survival was only 1.9 months.  Keep in mind that this only applies to oral use - which may mean not enough of the drug is getting to the tumor, and using it by itself.. it is possible that using it in other ways with other treatments may help.

  237. [09/16/2012] Gross Total Resection Rates in Contemporary Glioblastoma Surgery: Results of an Institutional Protocol Combining 5-ALA Intraoperative Fluorescence Imaging and Brain Mapping.  5-ALA is a dye used during brain tumor surgery to let the surgeon know where the tumor is.  This article shows that it helps increase the chances of a total resection for a Glioblastoma, without increasing the complication rate.  This dye is approved for use in Europe, but the USA FDA has not yet approved it here.  It is in clinical trials here and hopefully will be approved soon.

  238. [09/04/2012] Gross Total Resection Rates in Contemporary Glioblastoma Surgery: Results of an Institutional Protocol Combining 5-ALA Intraoperative Fluorescence Imaging and Brain Mapping.  5-ALA is approved in Europe and is in clinical trials in the USA.  It helps the doctors to tell what is tumor and what is normal brain when doing a surgery.  This should be approved soon here in the USA and should be used in most brain tumor surgeries. I do not understand what is holding it up.

  239. [08/30/2012] FDA Approves Novartis Tumor Drug for Children  This is for a rare pediatric brain tumor - but it is the first drug ever designed specifically for pediatric brain tumors!

  240. [08/15/2012] Suicide Gene killing deadly brain cancer: Nappanee woman in national study  This is one of the more promising new treatments out there... I am keeping an eye on it.

  241. [08/14/2012] Electric Helmet Treats Brain Tumors Describes this new, FDA approved treatment for brain tumors:  Includes a nice video of a patient using the Novocure NOVO TTF100A device.  For more details on the Novocure device, visit:   http://virtualtrials.com/novocure

  242. [08/09/2012] Impact of radiotherapy delay on survival in glioblastoma.

  243. [08/01/2012] super selective intra arterial delivery of chemotherapy - including Avastin. lecture - details. Edison NJ 8/2/2012

  244. [07/21/2012] Brain Tumor Removal Device Cleared for Use in New Zealand

  245. [07/15/2012] Musella Foundation Awards Grant to Tocagen to Support Clinical Study of Toca 511 & Toca FC in Brain Cancer Patients

  246. [06/22/2012] The effects of the NICE Technology Appraisal 121 (Gliadel and Temozolomide) on survival in high-grade glioma.

  247. [06/22/2012] Safety and efficacy of Gliadel wafers for newly diagnosed and recurrent glioblastoma.

  248. [06/14/2012] Fred Hutch Spinoff Blaze Bioscience Pulls in $5M For ‘Tumor Paint’

  249. [06/13/2012] Radiotherapy and concomitant temozolomide may improve survival of elderly patients with glioblastoma.

  250. [05/24/2012] Novocure(TM) Certifies Eight Additional Clinical Centers of Excellence to Treat Most Common Brain Tumor with Tumor Treating Fields (TTFields) Therapy

  251. [05/23/2012] Drug shrinks melanoma metastases in the brain

  252. [05/18/2012] Northwest Bio Provides Update On DCVax®-L Brain Cancer Trial [Upgraded to phase 3!]

  253. [05/05/2012] Mayor Bloomberg Declares June 9th Neurosurgery Charity Softball Tournament Day in NYC

  254. [05/03/2012] New Gamma Knife at South Nassau Communities Hospital Perfects Treatment of Brain Tumors, Malformations

  255. [04/25/2012] MR-guided LITT for recurrent glioblastomas.

  256. [04/25/2012] Radiotherapy with concurrent or sequential temozolomide in elderly patients with glioblastoma multiforme.

  257. [04/20/2012] Test can reliably diagnose and monitor brain tumor without the need for surgery

  258. [04/06/2012] Intraoperative tissue fluorescence using 5-aminolevolinic acid (5-ALA) is more sensitive than contrast MRI or amino acid positron emission tomography ((18)F-FET PET) in glioblastoma surgery.

  259. [04/06/2012] Study Suggests Vaccine May Help Kids With Brain Cancer

  260. [04/03/2012] Study Suggests Vaccine May Help Kids With Brain Cancer

  261. [04/03/2012] Impact of the per-operatory application of GLIADEL wafers (BCNU, carmustine) in combination with temozolomide and radiotherapy in patients with glioblastoma multiforme: Efficacy and toxicity.

  262. [03/27/2012] Single antibody shrinks variety of human tumors transplanted into mice, study shows

  263. [03/26/2012] Boston terrier from Newport News on front line of cancer research

  264. [03/26/2012] Noninvasive imaging can detect mutations within a brain tumor

  265. [02/25/2012] NW Bio Teams With the American Red Cross in DCVax® Program Initial Focus On Current 240-Patient GBM Clinical Trial

  266. [02/20/2012] IBTA E NEWS FEBRUARY 2012

  267. [02/15/2012] `First-in-human` drug for malignant glioma available in experimental trial

  268. [02/09/2012] JFK (Edison, NJ )Becomes First East Coast Site to Open Clinical Trial of New Treatment Under Investigation for Aggressive Brain Tumors

  269. [02/09/2012] Bevacizumab (Avastin) improves quality of life in patients with recurrent glioblastoma.

  270. [01/30/2012] Verastem IPO Validates Investor Interest In Cancer Stem Cell Approach

  271. [01/09/2012] New trial sites for DCVax and Novocure added to our Clinical Trials and Noteworthy Treatments For Brain Tumors website!

  272. [01/09/2012] NW Bio Reaches 25 Clinical Trial Sites Open and Recruiting By the End of Q4, 2011 (For DCVax Brain Tumor Vaccine)

  273. [01/05/2012] Novel Brain Tumor Vaccine Acts Like Bloodhound to Locate Cancer Cells

  274. [12/22/2011] Improved Treatments for Brain Cancers Highlighted at Annual Society of Neuro-Oncology (SNO) Meeting

  275. [12/19/2011] IBTA E News November-December 2011

  276. [12/19/2011] New Treatment Protocol at Westchester Brain Tumor Program Offers a Ray Of Hope When a Deadly Brain Cancer Recurs

  277. [12/03/2011] Topic: IMMUNOTHERAPY IM-07 RESULTS OF A PILOT STUDY TO EVALUATE THE EFFECTS OF VACCINATIONS WITH HLA-A2-RESTRICTED GLIOMA ANTIGEN-PEPTIDES IN COMBINATION WITH POLY-ICLC FOR CHILDREN WITH NEWLY DIAGNOSED MALIGNANT BRAIN STEM GLIOMAS, NON-BRAINSTEM HIGH-GRADE GLIOMAS, OR RECURRENT UNRESECTABLE GLIOMAS

  278. [12/03/2011] Patient Receives First Prescription for FDA-Approved Brain Tumor Treatment

  279. [12/02/2011] Novocure™ Establishes Initial Clinical Centers of Excellence for Treatment of Recurrent Glioblastoma Multiforme with Tumor Treating Fields (TTFields)™ Therapy

  280. [12/01/2011] New Evidence Links Virus to Brain Cancer

  281. [11/30/2011] NICO Corporation Progresses Minimally Invasive Corridor Neurosurgery by Extending Myriad Product Line for Brain Tumor Removal

  282. [11/10/2011] Glioblastoma survival in the United States before and during the temozolomide era.

  283. [11/10/2011] Temozolomide plus radiotherapy for glioblastoma in a Canadian province: Efficacy versus effectiveness and the impact of O6-methylguanine-DNA-methyltransferase promoter methylation.

  284. [11/07/2011] Cleveland Clinic, UH testing therapies on deadly brain tumors

  285. [10/30/2011] Del Mar Pharmaceuticals Initiates Glioblastoma Clinical Trial

  286. [10/22/2011] The challenges of managing glioblastoma multiforme in developing countries: a trade-off between cost and qu ality of care.

  287. [10/22/2011] Phase II study of carboplatin, irinotecan, and bevacizumab for bevacizumab naïve, recurrent glioblastoma.

  288. [10/10/2011] METASTASIZED BRAIN CANCER TREATED WITH ISORAY`S CESIUM-131 IN WORLD`S FIRST AT N.Y. PRESBYTERIAN/WEILL CORNELL MEDICAL CENTER

  289. [09/29/2011] Multi-Session Gamma Knife Radiosurgery Gaining Traction in North America to Treat Patients With Cancers in Brain and Skull Base

  290. [09/29/2011] Winthrop Study For Patients With Brain Tumors

  291. [09/25/2011] Swedish`s Ivy Brain Tumor Center Launches Two New Clinical Trials to Treat Brain Cancer

  292. [09/25/2011] Surgical Innovation: Brain Cancer Cells Glow with New Drug

  293. [09/21/2011] Emerging Technologies In Brain Cancer Therapy

  294. [09/17/2011] Clinical Trial Tests Investigational New Drug for Malignant Brain Tumors

  295. [09/16/2011] Zofran (ondansetron): Drug Safety Communication - Risk of Abnormal Heart Rhythms

  296. [09/13/2011] Pharma Strategy Blog: Roche files vismodegib for basal cell carcinoma with FDA [Editor`s note: although not for brain tumors - this may open the door for using it for some types of brain tumors]

  297. [09/12/2011] ImmunoCellular Therapeutics Announces 55% Overall Survival at Three years from Phase I Study in Glioblastoma

    38% of patients disease free at 3 years



  298. [09/09/2011] IBTA E NEWS AUGUST-SEPTEMBER 2011

  299. [08/19/2011] Phase IB Study of Gene-Mediated Cytotoxic Immunotherapy Adjuvant to Up-Front Surgery and Intensive Timing Radiation for Malignant Glioma.

  300. [08/19/2011] Neurosurgical management and prognosis of patients with glioblastoma that progress during bevacizumab treatment.

  301. [08/07/2011] NWBT Announces Further Expansion of Clincal Sites in Ongoing Brain Cancer Trial

  302. [07/31/2011] IBTA E NEWS JULY 2011

  303. [07/25/2011] Threshold Pharmaceuticals Announces Initiation of Clinical Trial Evaluating TH-302 in Combination with Bevacizumab at University of Texas at San Antonio

  304. [07/21/2011] 54 Year old brain tumor patient becomes world champion taekwondo 7 months after surgery

  305. [07/17/2011] MGMT expression and promoter methylation status may depend on the site of surgical sample collection within glioblastoma: a possible pitfall in stratification of patients?

  306. [07/17/2011] The efficacy of carmustine wafers (Gliadel) for older patients with glioblastoma multiforme: prolonging survival.

  307. [07/14/2011] Metabolic targeting of lactate efflux by malignant glioma inhibits invasiveness and induces necrosis: an in vivo study.

  308. [07/09/2011] Just Add Water and … Treat Brain Cancer

  309. [07/09/2011] NewYork-Presbyterian Radiation Oncology and Neurosurgery Programs Bolstered With Next-Generation Gamma Knife and Linear Accelerator

  310. [07/09/2011] Cilengitide in patients with recurrent glioblastoma: the results of NABTC 03-02, a phase II trial with measures of treatment delivery

  311. [07/09/2011] MicroRNAs in Brain Tumors : A New Diagnostic and Therapeutic Perspective?

  312. [07/08/2011] Musella Foundation awards $50,000 grant for brain tumor vaccine reasearch!

  313. [06/16/2011] Tumor treating fields: concept, evidence and future.

  314. [06/16/2011] Phase 2 study of carboplatin, irinotecan, and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy.

  315. [06/16/2011] Specialised Therapeutics to License Brain Tumour Visualisation Drug Gliolan in Australia & NZ

  316. [06/13/2011] Stemline Therapeutics Announces Oral Presentation of Positive Phase I/II Trial Results with Novel Brain Cancer Vaccine at ASCO

  317. [06/07/2011] Tocagen`s First-in-Human Clinical Trial of Toca 511 Enrolling Patients with High Grade Glioma

  318. [06/06/2011] New Data From Phase 2 Brain Cancer Study With Prophage Series G-200 (HSPPC-96) Shows Improved Overall Survival

  319. [06/04/2011] NICO Corporation Receives Health Canada Approval for Brain Tumor Removal Tool

  320. [06/04/2011] Study finds vaccine extends recurrent GBM survival rates by 2 to 3 times

  321. [05/28/2011] Northwest Biotherapeutics Further Expands Ongoing Brain Cancer Trial

  322. [05/24/2011] Neurosurgeons Shed Scrubs and Suit up in Softball Uniforms to Battle Pediatric Brain Tumors Come Out to the Ball Game in Support of Crucial Neurosurgical Research

  323. [05/19/2011] Injected patients with a virus to help kill brain tumors

  324. [05/11/2011] FREE Cleveland Clinic online chat today 2:30 - 3:30pm (Eastern Time)

  325. [05/10/2011] Monmouth Medical Center offers Leskell gamma knife for brain surgery

  326. [05/03/2011] Northwest Biotherapeutics` Ongoing Brain Cancer Trial Recruiting Additional Patients at Four Medical Centers Across US

  327. [04/29/2011] Neurosurgeons Shed Scrubs and Suit up in Softball Uniforms to Battle Pediatric Brain Tumors

  328. [04/27/2011] Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion.

  329. [04/27/2011] The natural history of extracranial metastasis from glioblastoma multiforme.

  330. [04/25/2011] NICO Corporation passes 1,000 case mark; receives CE Mark approval for use of minimally invasive brain surgery tool in European markets

  331. [04/15/2011] FDA clears first-of-a-kind device for brain cancer (Mentions Musella Foundation!)

  332. [04/15/2011] Identification of Protein Biomarkers Offers Promise for Children with Deadly Brainstem Gliomas (Funded by the Musella Foundation!)

  333. [03/20/2011] Dendritic Cell Vaccine Increases Median Survival in Patients with Deadly Brain Cancer

  334. [03/09/2011] A phase I/II trial of the histone deacetylase inhibitor, romidepsin, for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03.

  335. [03/02/2011] Pathological characterization of the glioblastoma border as shown during surgery using 5-aminolevulinic acid-induced fluorescence.

  336. [02/24/2011] The Musella Foundation For Brain Tumor Research & Information, Inc announces that it has awarded 2 grants for brain tumor research:

  337. [02/23/2011] Stemline Therapeutics Licenses Phase I/II Brain Cancer Vaccine - Shows Promise in Clinical Trial Conducted at University of Pittsburgh

  338. [02/18/2011] Glioma cells showing IDH1 mutation cannot be propagated in standard cell culture conditions

  339. [02/18/2011] Neurosurgeon Pioneers Handheld Laser for Tumors Deep in Skull Base

  340. [02/18/2011] New Minimally Invasive Brain Tumor Removal Tool Introduced to Neurosurgeons at NASBS

  341. [02/12/2011] Retrospective Comparison of Chemoradiotherapy Followed by Adjuvant Chemotherapy, With or Without Prior Gliadel Implantation (Carmustine) After Initial Surgery in Patients With Newly Diagnosed High-Grade Gliomas.

  342. [02/09/2011] Brain Tumor Vaccine Trial-Phase II Trial of ICT-107- opens in NJ!

  343. [02/03/2011] ImmunoCellular Therapeutics Ltd. (IMUC.OB) Enrolls First Patient for Phase II Study for Brain Tumor Candidate

  344. [02/03/2011] UT`s targeted particle fools brain`s guardian to reach tumors

  345. [01/29/2011] Upcoming meningioma webinar (From the National Brain Tumor Society

  346. [01/04/2011] Healthcare Innovators Announce Clinical Trials for Brain Tumor Vaccine

  347. [12/28/2010] The paradoxical effect of bevacizumab in the therapy of malignant gliomas

  348. [12/23/2010] ImmunoCellular Therapeutics (IMUC): At the Forefront of Brain Tumor Treatment

  349. [12/23/2010] Electrical Device for Cancer Treatment Polarizes Audiences

  350. [12/17/2010] Insight offers new angle of attack on variety of brain tumors

  351. [12/07/2010] Phase II Study of Bevacizumab Plus Temozolomide During and After Radiation Therapy for Patients With Newly Diagnosed Glioblastoma Multiforme

  352. [12/04/2010] New Drugs Target Recurrent Meningioma

  353. [12/02/2010] Device for Glioblastoma May Offer Advantage Over Chemo

  354. [11/28/2010] Prothrombotic state in glioblastoma multiforme: an evaluation of the procoagulant activity of circulating microparticles

  355. [11/15/2010] Cancer treatment shows promise

  356. [11/08/2010] IsoRay Awarded More Than $526,000 in Federal Grants for Breast, Brain and Lung Cancer

  357. [10/30/2010] FDA approves Afinitor for brain tumor treatment

  358. [10/22/2010] SUBGROUP AND QUALITY OF LIFE ANALYSES OF THE PHASE III CLINICAL TRIAL OF NOVOTTF-100A VERSUS BEST STANDARD CHEMOTHERAPY FOR RECURRENT GLIOBLASTOMA [Abstracts from SNO]

  359. [10/06/2010] Surgeons use florescent light to target brain cancer (Editor`s Note: this is a must see video!)

  360. [10/04/2010] David M. Bailey 2/26/1966 - 10/2/2010

  361. [09/24/2010] Childhood Cancer Survivors Show Sustained Benefit From Common ADHD Medication

  362. [09/23/2010] Selective Serotonin Reuptake Inhibitors, Glioblastoma Multiforme, and Impact on Toxicities and Overall Survival: The Mayo Clinic Experience.

  363. [09/08/2010] UTAH MOM OF FIVE COMES THROUGH BRAIN SURGERY WITH HER HEARING AND HER SMILE

  364. [09/04/2010] ImmunoCellular Therapeutics Issues Letter to Shareholders

  365. [09/03/2010] Surgeons Use New Tools to Treat Inoperable Brain Tumors

  366. [08/29/2010] Accumulation o f CD133-positive glioma cells after high-dose irradiation by Gamma Knife surgery plus external beam radiation.

  367. [08/29/2010] Poor drug distribution as a possible explanation for the results of the PRECISE trial.

  368. [08/17/2010] ImmunoCellular Therapeutics Announces 2010 Second Quarter Results (And reports 100% 1 year survival!)

  369. [08/15/2010] First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a mu lticenter experience.

  370. [08/03/2010] Scientists Develop “Designer Protein,” Opening New Door in Cancer Research

  371. [08/03/2010] Long-Term Follow-Up of DCVax®-Treated Brain Cancer Patients Shows 33% of Patients Reached 4-Year Survival and 27% Have Reached or Exceeded 6-Year Survival

  372. [07/07/2010] Hypofractionated stereotactic radiation therapy: an effective therapy for recurrent high-grade gliomas.

  373. [07/03/2010] The anti-cancer efficacy of curcumin scrutinized through core signaling pathways in glioblastoma.

  374. [06/18/2010] Can high-dose fotemustine reverse MGMT resistance in glioblastoma multiforme?

  375. [06/16/2010] Is Northwest Biotherapeutics (OTC:NWBO) Ready To Mount A Comeback?

  376. [06/08/2010] FDA approves first human neural stem cell clinical trial to treat brain tumors

  377. [06/08/2010] Exceptional Survival Data, Lower Costs Key to the Competitive Advantage of DCVax(R) - Northwest Biotherapeutics` Vaccine for Multiple Cancers

  378. [06/08/2010] Brain cancer vaccine shows promise

  379. [06/07/2010] Children`s Memorial Hospital, Chicago, First Children`s Hospital in Illinois to Acquire New Device for Pediatric Brain and Spine Tumor Removal

  380. [06/07/2010] Initial Experience Involving Treatment and Retreatment With Carmustine Wafers in Combination With Oral Temozolomide: Long-term Survival in a Child With Re lapsed Glioblastoma Multiforme.

  381. [06/05/2010] The Mike Overall Golf Classic to be held June 21, 2010 - Beaumont, Texas

  382. [06/05/2010] Interim Positive Results From Phase 2b Brain Cancer Study With Rindopepimut (PF-04948568 or CDX-110) Presented at 46th Annual ASCO Meeting

  383. [06/04/2010] ImmunoCellular Therapeutics` ICT-107 Demonstrates 80 Percent Survival at 2 Years in Phase I Study of Newly Diagnosed Glioblastoma Patients

  384. [05/18/2010] IBTA E-News May 2010

  385. [05/13/2010] Generic drug shows promise for brain tumour treatment, study shows

  386. [05/11/2010] THE SAME BRAIN TUMOR TISSUE THAT TAKES LIVES, CAN BE USED TO SAVE THEM

  387. [04/29/2010] `Landmark` cancer vaccine gets FDA approval (Editor`s Note: this is for Prostate Cancer, but I am sending it because it is the first cancer vaccine to get approval. Hopefully making it easier to get brain tumor vaccines approved!]

  388. [04/28/2010] Patient Trial of Personalized Two-Drug Therapy for Brain Tumors Launched

  389. [04/23/2010] Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial.

  390. [04/16/2010] Targeted Agent Blocked Growth of Deadly Brain Cancer in Preclinical Studies

  391. [03/26/2010] AVASTIN now approved (In Canada) to treat colorectal, breast, lung and brain cancer

  392. [03/17/2010] Lycopene in treatment of high-grade gliomas: A pilot study.

  393. [03/16/2010] New Brain Tumor Videos Added to Virtualtrials.com

  394. [03/16/2010] IBTA E-News March 2010

  395. [03/13/2010] Swedish Neuroscience Institute (in Seattle, Wash.) Brain Cancer Surgeon Publishes Major Feature Article in Scientific American MIND

  396. [03/05/2010] Phase II trial of pazopanib (GW786034), an oral multi-targeted angiogenesis inhibitor, for adults with recurrent glioblastoma (North American Brain Tumor Consortium Study 06-02).

  397. [02/20/2010] O6-methy lguanine DNA-methyltransferase methylation status can change between first surgery for newly diagnosed glioblastoma and second surgery for recurrence: clinical implications./h3>

  398. [02/20/2010] Phase II trial of low-dose continuous (metronomic) treatment of temozolomide for recurrent glioblastoma.

  399. [02/19/2010] Drug allows surgeons to better see brain tumors

  400. [02/16/2010] Cancer Research UK and immatics Biotechnologies to trial vaccine for brain cancer

  401. [02/11/2010] New Scientific Publication Highlights Long-Term Survival of Brain Cancer Patients Treated With Peregrine Pharmaceuticals` Cotara(R)

  402. [02/01/2010] Radiation Therapy Harms the Brain, Causing Memory and Attention Problems

  403. [01/28/2010] Is there an advantage to administering bevacizumab directly to brain tumors using microcatheters?

  404. [01/25/2010] New Study Shows ImmunoCellular Therapeutics` Lead Investigational Cancer Vaccine ICT-107 Targets Cancer Stem Cells

  405. [01/17/2010] IBTA E-News January 2010

  406. [01/13/2010] Brain Cancer: Searching for a Breakthrough with Cell & Gene Therapy Thursday, January 28, 2010 7:00 p.m. Bruce Museum, Greenwich, Connecticut

  407. [01/10/2010] Small Addition to Cancer Drug May Make Big Difference

  408. [12/23/2009] Brain Cancer: Searching for a Breakthrough with Cell & Gene Therapy Thursday, January 28, 2010

  409. [12/02/2009] Brain Tumor Cells Made More Responsive to Radiation

  410. [12/02/2009] Peregrine Completes Patient Enrollment in Cotara(R) Dose Confirmation and Dosimetry Brain Cancer Trial

  411. [11/30/2009] Crosstalk between critical cell-signaling pathways holds clues to tumor invasion and metastasis

  412. [11/21/2009] Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study.

  413. [11/13/2009] Neurosurgery Resident`s Book Helps Ease Youths` Fears About Brain Surgery

  414. [11/12/2009] Six year survival after prolonged temozolomide treatment in a 30-year-old patient with glioblastoma.

  415. [11/03/2009] MagForce Successfully Completes Final Clinical Trials for Nano-Cancer Therapy

  416. [11/03/2009] Gamma knife treatment for glioblastomas shows promising results - Survival rate increased by almost 4 months

  417. [10/22/2009] Northwest Biotherapeutics announces long-term data from Phase I and Phase I/II clinical trials of DCVax-Brain

  418. [10/18/2009] Cancer drug crosses key hurdle in brain: study

  419. [10/18/2009] IBTA October 2009 E-News

  420. [10/16/2009] Whole-brain radiotherapy after surgery or radiosurgery not recommended for all patients with brain metastases

  421. [10/16/2009] New protocol may improve rare pediatric brain cancer survival

  422. [10/05/2009] Malignant Brain Tumors: Chemotherapy Alone Is Just As Effective As Radiation / New Positive Prognostic Factor Found

  423. [10/05/2009] Chemotherapy Alone Is As Effective As Radiation After Brain Tumor Surgery

  424. [09/26/2009] Gliomas exploit Immune Cells of the Brain for Rapid Expansion

  425. [09/24/2009] Saint Johns Health Center today announced the appointment of world-renowned neurosurgeon Amin Kassam, MD, as Director of the new Saint John’s Neuroscience Institute

  426. [09/22/2009] Experts express hope for fight against brain tumors

  427. [09/07/2009] Small Cap Stocks Battling Brain Cancer

  428. [09/03/2009] Treating Radiation Necrosis of the Brain

  429. [08/11/2009] Radiation Linked to Cognitive Decline in Brain Cancer

  430. [08/04/2009] `Batman` cancer treatment lands U of M funding for clinical trial

  431. [07/14/2009] CVM Canine brain tumor clinical trials

  432. [07/09/2009] VEGF Inhibitor Shows Promise in Neurofibromatosis

  433. [06/30/2009] Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma.

  434. [06/25/2009] Antigenics Announces Expansion of Investigator-Sponsored Study for Glioma

  435. [06/20/2009] Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q.

  436. [06/20/2009] Long-term seizure outcomes in adult patients undergoing primary resection of malignant brain astrocytomas

  437. [06/12/2009] Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy.

  438. [06/01/2009] Pfizer and Celldex Therapeutics Present Update on CDX-110 (PF-04948568) Phase 2 Brain Cancer Studies at 45th Annual ASCO Meeting

  439. [06/01/2009] Most common brain cancer may originate in neural stem cells

  440. [06/01/2009] Drug Made From Cottonseed May Slow Brain Cancer, Researchers Say

  441. [05/25/2009] Treating Untreatable Brain Tumors: FDA Approves New Laser Surgery

  442. [05/24/2009] IBTA E-News May 24 2009

  443. [05/14/2009] Very late relapses in glioblastoma long-term survivors.

  444. [05/14/2009] A phase I trial of tumor-associated antigen-pulsed dendritic cell immunotherapy for patients with brain stem glioma and glioblastoma.

  445. [05/14/2009] Bevacizumab in combination with radiotherapy plus concomitant and adjuvant temozolomide for newly diagnosed glioblastoma: Update progression-free survival, overall survival, and toxicity.

  446. [05/07/2009] Surrogate markers predict angiogenic potential and survival in patients with glioblastoma multiforme.

  447. [05/07/2009] The survival impact of postoperative infection in patients with glioblastoma multiforme.

  448. [05/07/2009] Free Neurological Seminar - May 9th, Long Island, NY

  449. [05/05/2009] FDA GRANTS ACCELERATED APPROVAL OF AVASTIN FOR BRAIN CANCER

  450. [04/29/2009] IBTA E-Newsletter

  451. [04/01/2009] FDA Advisory Committee Unanimously Recommends Accelerated Approval of Avastin for Previously Treated Brain Cancer (Glioblastoma)

  452. [04/01/2009] Speaker From Duke University ~ Asheville, NC

  453. [03/28/2009] Significant headache improvement after transsphenoidal surgery in patients with small sellar lesions.

  454. [03/18/2009] Make A World Record In Cancer Fight

  455. [03/08/2009] Completely endoscopic resection of intraparenchymal brain tumors.

  456. [03/08/2009] Tumor regrowth between surgery and initiation of adjuvant therapy in patients with newly diagnosed glioblastoma.

  457. [03/08/2009] Localized BCNU chemotherapy and the multimodal management of malignant glioma.

  458. [03/07/2009] Northwest Biotherapeutics reported encouraging results for DCVax Brain Tumor Vaccine

  459. [03/07/2009] Bradmer provides clinical trial update and announces evaluation of strategic alternatives

  460. [03/05/2009] Cancer Treatment Kills Tumors by `Cooking` New Laser Approach Attacks Remote Brain Tumors Once Unreachable With Surgery

  461. [03/04/2009] Independent association of extent of resection with survival in patients with malignant brain astrocytoma.

  462. [02/19/2009] Update of Long-Term Data on Brain Cancer Patients Receiving DCVax(R)-Brain Continues to Show Striking Improvements in Delay of Disease and Survival

  463. [02/14/2009] CNN story helps surgeon perform `lifesaving` op

  464. [02/11/2009] Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034.

  465. [02/11/2009] Phase II Trial of Temozolomide Plus O6-Benzylguanine in Adults With Recurrent, Temozolomide-Resistant Malignant Glioma.

  466. [02/08/2009] MILES FOR HOPE TO BREAK WORLD RECORD FOR BRAIN TUMOR AWARENESS

  467. [02/04/2009] New Laser For Neurosurgery Allows Greater Precision And Efficiency For Removal Of Complex Tumors

  468. [02/02/2009] Safety and Efficacy of Bevacizumab with Hypofractionated Stereotactic Irradiation for Recurrent Malignant Gliomas.

  469. [02/02/2009] State-of-the-Art Therapy for Glioblastoma Multiforme

  470. [01/22/2009] NOVEL DEVICE SHOWN TO BENEFIT SURVIVAL FOR BRAIN CANCER PATIENTS WHEN COMBINED WITH CHEMOTHERAPY

  471. [01/15/2009] New vaccine trial opens for people with low grade astrocytoma and oligodendrogliomas

  472. [01/12/2009] Gene therapy eliminates brain tumors through selective recruitment of immune cells

  473. [12/31/2008] Short Delay in Initiation of Radiotherapy May Not Affect Outcome of Patients With Glioblastoma: A Secondary Analysis From the Radiation Therapy Oncology Group Database.

  474. [12/25/2008] ImmunoCellular Therapeutics’ Cancer Vaccine Demonstrates Immune Response against Brain Cancer in Clinical Trial

  475. [12/15/2008] IBTA Newsletter

  476. [12/11/2008] 21st Century Brain Surgery: Minimally Invasive Endonasal Approach, Experienced Surgeons Give Patients the Advantages They Need

  477. [12/05/2008] Drug slows brain cancer, Calgary researchers say

  478. [12/04/2008] Ranbaxy in pact to market BioPro`s brain tumour drug (Gliadel) in India news

  479. [11/26/2008] RTOG Reports That Chemotherapy Added to Radiotherapy Improves Survival (For low grade gliomas)

  480. [11/26/2008] Final Data From Phase 1 Investigator-Sponsored Trial of Oncophage® Cancer Vaccine in Glioma Presented at the Society for Neuro-Oncology’s Annual Meeting

  481. [11/25/2008] Brain-cancer center at Swedish maps tumors to design treatment

  482. [11/25/2008] STUDIES SHOW NOVEL DEVICE MAY ENHANCE CHEMOTHERAPY TREATMENT IN BRAIN TUMORS

  483. [11/17/2008] The relative risk of brain cancer

  484. [11/06/2008] New Treatment Guidelines for Newly Diagnosed Glioblastoma Issued by American Association of Neurological Surgeons/Congress of Neurological Surgeons

  485. [11/05/2008] Bradmer sponsors physician panel to raise awareness of brain cancer treatments (Live Webcast!)

  486. [11/05/2008] 7th Annual BRAIN TUMOR AWARENESS DAY Conference on Sunday, November 16th, 2008 in NY

  487. [10/19/2008] Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3

  488. [10/19/2008] IBTA E-NEWSLETTER 15 October 2008

  489. [10/17/2008] Swedish in Seattle Unveils State-of-the-Art Brain Tumor Center Combining Advanced Treatment With Innovation in Research

  490. [10/06/2008] UCSF surgeon changes study of brain tumors

  491. [10/04/2008] A phase II trial with cetuximab, bevacizumab, and irinotecan for patients with primary glioblastomas and progression after radiation therapy and temozolamide.

  492. [10/04/2008] Prospective phase II trial for recurrent high-grade gliomas with capacitive coupled low radiofrequency (LRF) hyperthermia.

  493. [10/03/2008] Comparative analysis of temozolomide (TMZ) versus 1,3-bis (2-chloroethyl)-1 nitrosourea (BCNU) in newly diagnosed glioblastoma multiforme (GBM) patients.

  494. [10/03/2008] Radiosurgery and carcinogenesis risk.

  495. [10/03/2008] A phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: a North American Brain Tumor Consortium (NABTC01-05).

  496. [09/28/2008] Median Brain Cancer Survival Doubles in Vaccine Trials

  497. [09/26/2008] Initial Whole-Brain Radiation for Brain Metastases Questioned

  498. [09/14/2008] Long-Term Phase I and Phase I/II Trial Data Continue to Show Striking Improvement in Survival of Brain Cancer Patients Who Receive DCVax(R)-Brain

  499. [09/05/2008] Researchers Detect Genetic Defects Guilty Of Deadliest Cancers

  500. [09/05/2008] New clues found to treat brain cancer

  501. [08/30/2008] Phase II Pre-radiation R115777 (Zarnestra) in newly diagnosed GBM with residual enhancing disease.

  502. [08/30/2008] Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol.

  503. [08/29/2008] AN UPDATE ON THE EFFECTS OF NEURADIAB ON PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA MULTIFORME (GBM)

  504. [08/26/2008] Health-related quality of life of long-term high-grade glioma survivors

  505. [08/26/2008] Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3

  506. [08/24/2008] Bike Tour Charity Event to Support the Fight against Brain Cancer

  507. [08/11/2008] Rare Device Aids N.Y. Brain Surgeons

  508. [08/10/2008] Preliminary Cerepro (R) Phase III Results Meet Primary Endpoint - Operable Primary Malignant Glioma

  509. [08/10/2008] Bevacizumab and irinotecan therapy in glioblastoma multiforme: a series of 13 cases.

  510. [08/10/2008] Dose-intensity temozolomide after concurrent chemoradiotherapy in operated high-grade gliomas.

  511. [07/31/2008] Bradmer initiates enrollment in Phase III GLASS-ART Trial in primary glioblastoma multiforme

  512. [07/26/2008] Use of Gliadel (BCNU) Wafer in the Surgical Treatment of Malignant Glioma: A 10-Year Institutional Experience.

  513. [07/17/2008] Bradmer reports progression free survival data from previous Phase II glioblastoma multiforme trials

  514. [07/03/2008] Does Herpes Cause Brain Cancer?

  515. [06/28/2008] Taming, Then Aiming, Viruses At Brain Tumors - "Engineered" Viruses May Hold Promise For Cancer Treatment

  516. [06/26/2008] The Lori Arquilla Andersen Foundation Holds Fourth Annual Gray Tie Ball to Raise Funds for Awareness, Advocacy and Research to Find the Cure for Brain Cancer

  517. [06/17/2008] Second-line chemotherapy with fotemustine in temozolomide-pretreated patients with relapsing glioblastoma: a single institution experience.

  518. [06/11/2008] 7/17/08 Seattle: Lecture: Advanced Brain Tumors: Treatment Options

  519. [05/28/2008] Surgeon`s trial study on cancer is hailed

  520. [05/28/2008] Glioma extent of resection and its impact on patient outcome.

  521. [05/28/2008] Incidence of early pseudo-progression in a cohort of malignant glioma patients treated with chemoirradiation with temozolomide.

  522. [05/24/2008] Hints of Progress in Drugs Treating Brain Cancer

  523. [05/20/2008] Study: Patients 75 years and older with brain tumors may benefit from more aggressive treatment

  524. [05/04/2008] Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas.

  525. [04/27/2008] Improving quality of life for brain tumor patients

  526. [04/27/2008] Experimental vaccine offers hope against brain cancer

  527. [04/27/2008] Cancer researchers receive NIH grant to advance brain tumor therapies from lab to clinical trials

  528. [04/21/2008] Cancer cells spread by releasing "bubbles"

  529. [04/20/2008] Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults

  530. [04/20/2008] Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors

  531. [04/20/2008] Outpatient brain tumor surgery: innovation in surgical neurooncology.

  532. [04/20/2008] No profit in drug, so virus fights cancer

  533. [04/17/2008] Drugs in the pipeline: new therapies that could change treatment strategies

  534. [04/14/2008] NOVOCURE PRESENTS RESULTS FROM BREAST CANCER PILOT STUDY (Mentions GBM also)

  535. [04/06/2008] A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients.

  536. [03/30/2008] Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.

  537. [03/30/2008] Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: Phase 1 trial in adults with malignant glioma.

  538. [03/30/2008] Glioblastoma multiforme: an emerging paradigm of anti-VEGF therapy.

  539. [03/30/2008] IBTA Newsletter

  540. [03/30/2008] Phase II Pilot Study of Bevacizumab in Combination With Temozolomide and Regional Radiation Therapy for Up-Front Treatment of Patients With Newly Diagnosed Glioblastoma Multiforme: Interim Analysis of Safety and Tolerability.

  541. [03/22/2008] Dan`s Fund Created at The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute to support Brain Cancer Research

  542. [03/18/2008] Progression-free survival: An important end point in evaluating therapy for recurrent high-grade gliomas

  543. [03/18/2008] Boron neutron capture therapy (BNCT) for glioblastoma multiforme: A phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).

  544. [03/18/2008] Phase II trial of irinotecan and thalidomide in adults with recurrent glioblastoma multiforme.

  545. [03/18/2008] Expression of glioma-associated antigens in pediatric brain stem and non-brain stem gliomas.

  546. [03/18/2008] Dan`s Fund created at Ohio State University

  547. [03/10/2008] New Drug for Brain Cancer Too Dangerous for Pediatric Patients

  548. [02/27/2008] Phase II trial of irinotecan and thalidomide in adults with recurrent glioblastoma multiforme

  549. [02/27/2008] Treatment of recurrent glioblastoma: can local delivery of mitoxantrone improve survival?

  550. [02/27/2008] “A Night of Hope & Dreams” Gala to Support Local Pediatric Brain Tumor Foundation

  551. [02/25/2008] A pilot study: 131I-Antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost.

  552. [02/25/2008] Effect of phenytoin on celecoxib pharmacokinetics in patients with glioblastoma.

  553. [02/25/2008] Phase I and Phase I/II DCVax(R)-Brain Data Continues to Show Significantly Improved Survival Rates for Brain Cancer Patients

  554. [02/15/2008] Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: Case study

  555. [02/15/2008] Caring for the brain tumor patient: Family caregiver burden and unmet needs

  556. [02/15/2008] Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma

  557. [02/15/2008] Safety and efficacy of permanent iodine-125 seed implants and carmustine wafers in patients with recurrent glioblastoma multiforme.

  558. [02/15/2008] State and trait anxiety and depression in patients with primary brain tumors before and after surgery: 1-year longitudinal study.

  559. [02/15/2008] Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma in elderly patients.

  560. [02/04/2008] The added value of concurrently administered temozolomide versus adjuvant temozolomide alone in newly diagnosed glioblastoma.

  561. [01/23/2008] Bill inspired by Oklahoma brain tumor patient

  562. [01/18/2008] MGI Pharma Reveals Results From Study Involving Dual Implantation Of Gliadel Wafer And Radioactive Seeds - Quick Facts [MOGN]

  563. [01/18/2008] Oncolytic measles virus strains in the treatment of gliomas.

  564. [01/14/2008] Operating Room “Navigation System” Increases Precision of Brain Surgery

  565. [01/13/2008] Antiangiogenic compounds interfere with chemotherapy of brain tumors due to vessel normalization.

  566. [01/13/2008] How To Get a Second Opinion - When Facing Brain Surgery

  567. [01/02/2008] Scientists Report Refinements to Brain Surgery

  568. [12/21/2007] MGMT Immunohistochemical Expression and Promoter Methylation in Human Glioblastoma.

  569. [12/19/2007] Neurognostics: Leading neuroscience centers select Neurognostics fMRI system

  570. [12/19/2007] ZFN Modified Cells Show Glioblastoma Killing in the Presence of Dexamethasone in Mouse Tumor Model

  571. [12/11/2007] New Image-Guided Radiotherapy System Benefits High-Risk Patients

  572. [12/09/2007] Adjuvant chemotherapy for adults with malignant glioma: a systematic review.

  573. [12/03/2007] Brain tumor center opens in Long Branch

  574. [12/02/2007] Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma

  575. [11/28/2007] Management of glioblastoma.

  576. [11/25/2007] Long-sustaining response in a patient with non-resectable, distant recurrence of glioblastoma multiforme treated by interstitial photodynamic therapy using 5-ALA: case report.

  577. [11/25/2007] Treating high grade gliomas in the elderly: the end of ageism?

  578. [11/17/2007] Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma.

  579. [11/16/2007] Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma

  580. [11/09/2007] Cancer vaccine

  581. [10/31/2007] Incidental Findings Common with Brain MRI

  582. [10/23/2007] Novel Vaccine For Aggressive Brain Tumors Tested By Mayo Clinic

  583. [10/22/2007] Drug may stave off brain tumor deaths

  584. [10/19/2007] Avastin seen as helpful against deadly brain tumor

  585. [10/19/2007] Clinical trial evaluating brain cancer vaccine is underway at NYU

  586. [10/17/2007] Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis.

  587. [10/15/2007] Antigenics`s Oncophage vaccine starts Phase II brain tumor trial

  588. [10/11/2007] First Patient Registered in Investigator-Sponsored Phase 2 Trial of Antigenics` Oncophage Cancer Vaccine in Glioma

  589. [09/28/2007] InSightec Resumes Clinical Trials for Non-Invasive Treatment of Brain Tumors

  590. [09/28/2007] Promising brain cancer drug moves to human trials

  591. [09/20/2007] Convection-enhanced delivery of nanoliposomal CPT-11 (irinotecan) and PEGylated liposomal doxorubicin (Doxil) in rodent intracranial brain tumor xenografts

  592. [09/09/2007] Improving alloreactive CTL immunotherapy for malignant gliomas using a simulation model of their interactive dynamics.

  593. [09/09/2007] Coincidence vs cause: cure in three glioblastoma patients treated with brachytherapy.

  594. [09/09/2007] Expression of Interleukin-13 Receptor {alpha}2 in Glioblastoma Multiforme: Implications for Targeted Therapies.

  595. [09/09/2007] Long-term survival with glioblastoma multiforme.

  596. [09/01/2007] The Fallacy of Single-Agent Chemotherapy for Cancer

  597. [08/30/2007] Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells

  598. [08/24/2007] Overlook Hospital only site in tri-state to offer new brain tumor vaccine

  599. [08/24/2007] Guidelines: Carmustine Implants and Temozolomide for Treatment of Newly Diagnosed High-Grade Glioma

  600. [08/21/2007] Angiogenesis Inhibition: The Next Frontier in Multimodal Therapy for Glioblastoma Multiforme

  601. [08/21/2007] Prospective study of awake craniotomy used routinely and nonselectively for supratentorial tumors.

  602. [08/21/2007] Gamma Knife surgery for benign meningioma.

  603. [08/17/2007] A new treatment to reduce swelling in the brain

  604. [08/10/2007] Brain Cancer Zapper

  605. [08/10/2007] Electric Fields Kill Tumors A promising device uses electric fields to destroy cancer cells in the brain.

  606. [07/28/2007] MIT IDs Link Between Brain Tumor Proteins Work Could Guide Drugs For Especially Aggressive Cancer

  607. [07/28/2007] Experimental Device Used To Treat Deadly Brain Cancer

  608. [07/06/2007] Addition of Gliadel® Wafer to Surgery and Radiation Effective for Brain Metastasis

  609. [06/30/2007] A synthetic molecule based on one found in frog egg cells could potentially be used to treat brain tumours.

  610. [06/29/2007] Canadian recommendations for the treatment of glioblastoma multiforme.

  611. [06/24/2007] Anti-inflammatory shows promise in brain tumor treatment

  612. [06/22/2007] Antisense Pharma: Promising Phase IIb Results of Targeted Therapy with AP 12009 in Recurrent Anaplastic Astrocytoma

  613. [06/20/2007] Improved median survival for glioblastoma multiforme following introduction of adjuvant temozolomide chemotherapy.

  614. [06/20/2007] High-dose chemotherapy with autologous stem cell rescue followed by posterior fossa irradiation for local medulloblastoma recurrence or progression after conventional chemotherapy.

  615. [06/20/2007] 3-D Ultrasound Provides In-depth View Of The Brain

  616. [06/16/2007] Clinical trial of autologous formalin-fixed tumor vaccine for glioblastoma multiforme patients.

  617. [06/16/2007] Radiotherapy plus concurrent and adjuvant procarbazine, lomustine, and vincristine chemotherapy for patients with malignant glioma.

  618. [06/16/2007] Vorinostat shows anti-cancer activity in recurrent gliomas

  619. [06/04/2007] Brain Tumor Activism Alert!

  620. [05/16/2007] Phase I Trial for ImmunoCellular Therapeutics Brain Tumor Vaccine Commences

  621. [05/16/2007] Multifocal Glioblastoma Multiforme: Prognostic Factors and Patterns of Progression.

  622. [04/22/2007] Differential effect of surgery and radiotherapy on neurocognitive functioning and health-related quality of life in WHO grade I meningioma patients.

  623. [04/19/2007] Data From Investigator-Sponsored Trial of Oncophage® Cancer Vaccine in Glioma Presented at American Association of Neurological Surgeons Annual Meeting

  624. [04/18/2007] Gamma knife surgery for focal brainstem gliomas.

  625. [04/18/2007] Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).

  626. [04/18/2007] Canadian robot melds brain surgery, rocket science

  627. [04/16/2007] UCSF brain tumor vaccine trial shows promising results

  628. [04/10/2007] Study: Localized radiation may work for some brain cancer patients

  629. [04/09/2007] Phase II trial of bevacizumab (Avastin) and irinotecan (CPT-11) in recurrent malignant glioma.

  630. [04/09/2007] Phase II trial of bevacizumab (Avastin) and irinotecan (CPT-11) in recurrent malignant glioma.

  631. [03/29/2007] Protherics starts trial of brain cancer therapy

  632. [03/26/2007] Erimos Pharmaceuticals Announces Phase I/Phase II Study of Terameprocol (EM-1421) In Conjunction with New Approaches to Brain Tumor Therapy (NABTT) Consortium

  633. [03/22/2007] Area doctor free of brain tumor for 22 months

  634. [03/10/2007] Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group.

  635. [03/10/2007] Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma.

  636. [03/09/2007] Myriad Genetics Initiates Phase 2 Clinical Trial of Azixa(TM) in Brain Cancer

  637. [03/09/2007] Northwest Biotherapeutics Adds UCLA as a Site to Its Pivotal Phase II Brain Cancer Trial

  638. [03/04/2007] Chemo wafers helping brain cancer patients live a better life

  639. [02/23/2007] Fighting brain cancer with electricity

  640. [02/17/2007] Electrodes fight brain cancer

  641. [02/15/2007] Swedish Neuroscience Institute Completes Major New Site for Advanced Neurosurgical Procedures

  642. [02/15/2007] First Patients Undergo Surgery in Northwest Biotherapeutics` Phase II Brain Cancer Trial

  643. [02/14/2007] `Gateway` gene discovered for brain cancer

  644. [01/26/2007] Advances in the Management of Glioblastoma Multiforme: An Expert Interview With Dr. Renato La Rocca From 2006 SNO

  645. [01/17/2007] Experiment at Stony Brook delivers drugs into arteries that feed the brain, targeting aggressive tumors

  646. [01/13/2007] Brain tumour treatment is a world first

  647. [01/08/2007] Neuralstem (OTC Bulletin Board: NRLS) Receives Notice of Intention to Grant Core Patent From European Patent Office

  648. [01/07/2007] Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme1

  649. [01/07/2007] Successful treatment of childhood intramedullary spinal cord astrocytomas with irinotecan and cisplatin

  650. [01/07/2007] Interstitial chemotherapy for malignant gliomas: the Johns Hopkins experience.

  651. [12/14/2006] Sangamo BioSciences and City of Hope Announce License Agreement and Research Collaboration to Develop Treatment for Brain Cancer

  652. [12/11/2006] http://www.jhu.edu/~gazette/2006/11dec06/11natura.html

  653. [12/07/2006] Drug that can fight brain cancer discovered

  654. [11/30/2006] Brain Tumor Resection Live Video - Today

  655. [11/28/2006] Bradmer Contracts With Prologue Research to Manage Multi-Center Pivotal Trial of Neuradiab in Brain Cancer

  656. [11/28/2006] Northwest Biotherapeutics Receives Institutional Review Board Approval to Accrue Patients in Phase II Brain Cancer Trial

  657. [11/22/2006] Levels and distribution of BCNU in GBM tumors following intratumoral injection of DTI-015 (BCNU-ethanol)

  658. [11/22/2006] The course of neurocognitive functioning in high-grade glioma patients

  659. [11/22/2006] Convection-enhanced delivery of a topoisomerase I inhibitor (nanoliposomal topotecan) and a topoisomerase II inhibitor (pegylated liposomal doxorubicin) in intracranial brain tumor xenografts

  660. [11/22/2006] Phase II study of Cloretazine for the treatment of adults with recurrent glioblastoma multiforme

  661. [11/22/2006] Phase III trial of carmustine and cisplatin compared with carmustine alone and standard radiation therapy or accelerated radiation therapy in patients with glioblastoma multiforme: North Central Cancer Treatment Group 93-72-52 and Southwest Oncology Group 9503 Trials.

  662. [11/22/2006] Visual field preservation after multisession cyberknife radiosurgery for perioptic lesions.

  663. [11/22/2006] The pathophysiologic mechanism of cerebellar mutism.

  664. [11/22/2006] CyberKnife radiosurgery for benign intradural extramedullary spinal tumors.

  665. [11/22/2006] Postoperative radiosurgery for malignant spinal tumors.

  666. [11/22/2006] Stem Cell-like Glioma Cells Promote Tumor Angiogenesis through Vascular Endothelial Growth Factor. [Editor`s Note: bevacizumab is the generic name for Avastin}

  667. [11/21/2006] University Evaluates New Device To Treat Brain Tumors

  668. [11/20/2006] NEOPHARM AnNOUNCES Presentation of FINAL SAFETY DATA FROM PHASE 1 TRIAL OF CINTREDEKIN BESUDOTOX for Newly Diagnosed Malignant Glioma

  669. [11/20/2006] Gliadel(R) Wafer Clinical Data Presented at Society for Neuro-Oncology Meeting

  670. [11/18/2006] Vaccine for brain tumors shows promising results

  671. [11/18/2006] Mayo Clinic Cancer Center -- Harnessing the Measles Virus to Attack Cancer

  672. [11/10/2006] Northwest Biotherapeutics Discusses Results From Clinical Trials In Brain Cancer At Two Conferences

  673. [11/10/2006] Long-term response of pituitary carcinoma to temozolomide. Report of two cases.

  674. [11/10/2006] Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomas.

  675. [11/10/2006] Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study.

  676. [11/10/2006] Jefferson Oncologists Show Less Radiation Just as Effective in Fighting Brain Tumor, Saving Hearing

  677. [10/30/2006] Northwest Biotherapeutics Discusses Results From Clinical Trials in Brain Cancer at Two Conferences

  678. [10/30/2006] Mayo Clinic Cancer Center -- Harnessing the Measles Virus to Attack Cancer Seeking a Cure for Glioblastoma Multiforme, Other Deadly Cancers

  679. [10/17/2006] Monitoring the effects of BCNU chemotherapy Wafers (Gliadel((R))) in glioblastoma multiforme with proton magnetic resonance spectroscopic imaging at 3.0 Tesla.

  680. [10/17/2006] Survival and quality of life after hypofractionated stereotactic radiotherapy for recurrent malignant glioma.

  681. [10/17/2006] A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme.

  682. [10/17/2006] Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from gruppo italiano cooperativo di neuro-oncologia (GICNO).

  683. [09/29/2006] Widow envisions brain tumor center

  684. [09/29/2006] UAB Launches Promising Brain Tumor Trial

  685. [09/18/2006] NEOPHARM Presents Updated CINTREDEKIN BESUDOTOX Phase I/II Median Survival Data at European Association of Neuro-Oncology (EANO) Meeting

  686. [09/14/2006] Experimental Brain Tumor Treatment

  687. [09/14/2006] Focusing Ultrasound on Brain Tumors — Investigating MRI-Guided Noninvasive Therapy Without Ionizing Radiation

  688. [09/14/2006] Combined Therapies May Boost Immune Response And Long-term Protection Against Brain Tumors

  689. [09/14/2006] New Strategy Improves Outcome For Children With Most Common Type Of Brain Tumor, UK

  690. [09/13/2006] Presbyterian Hospital of Dallas First in the United States to Perform Brain Surgery in State-of-the-Art Operating Room

  691. [09/08/2006] Stem Cells Improve Child Brain Cancer Outcomes

  692. [09/03/2006] Cancer Drug Aids An Anti-Cancer Virus

  693. [09/03/2006] Advocates guide patients through medical morass

  694. [08/25/2006] Postoperative radiosurgery for malignant spinal tumors.

  695. [08/07/2006] NEOPHARM PROVIDES UPDATE ON REIMBURSEMENT PROGRESS FOR CINTREDEKIN BESUDOTOX

  696. [08/05/2006] Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recurrent high-grade glioma.

  697. [08/03/2006] New Music Project Promotes Quality-of-Life After Cancer

  698. [07/29/2006] Scorpion Venom Tested Against Brain Cancer

  699. [07/25/2006] Cornell neurosurgeons and engineers bridge gap between Ithaca and New York City with promise of medical innovations

  700. [07/25/2006] Vascularity and angiogenesis as predictors of growth in optic pathway/hypothalamic gliomas.

  701. [07/20/2006] Intraoperative language localization in multilingual patients with gliomas.

  702. [07/15/2006] Phase III trial of chemotherapy plus radiotherapy compared with radiotherapy alone for pure and mixed anaplastic oligodendroglioma: Intergroup Radiation Therapy Oncology Group Trial 9402.

  703. [07/05/2006] A pilot clinical study of Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.

  704. [06/12/2006] Early necrosis following concurrent temozolomide and radiotherapy in adult patients with glioblastoma.

  705. [06/07/2006] Alternative schedules of adjuvant temozolomide in glioblastoma multiforme: A 6-year experience.

  706. [06/07/2006] Recovery of lower cranial nerve function after surgery for medullary brainstem tumors.

  707. [06/07/2006] Late sequela after treatment of childhood low-grade gliomas: a retrospective analysis of 69 long-term survivors treated between 1983 and 2003.

  708. [06/07/2006] Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial.

  709. [06/04/2006] Pharmacyclics Additional Data and New Analyses From Pivotal Phase 3 SMART Trial Presented at ASCO 2006

  710. [06/04/2006] New Drug Holds Promise for Type of Breast Cancer  (Editor`s Note: Mentions Brain Mets)

  711. [05/09/2006]  M. D. Anderson: Setting the Benchmark in Brain Tumor Treatment

  712. [05/09/2006]  Gliadel® wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial

  713. [05/05/2006] MIT loses EU court bid to extend cancer drug patent

  714. [05/03/2006] An Evening with David M. Bailey

  715. [05/03/2006] Ark`s £27.1M Funding Should Fuel Pipeline`s Confirmation [Brain tumor gene therapy]

  716. [05/03/2006] Northwest Biotherapeutics to Present Updated Brain Cancer Data at the International Society for Cellular Therapy Annual Meeting

  717. [05/02/2006] Scientist works to improve treatment for brain tumors

  718. [05/02/2006] Salvage chemotherapy With CPT-11 for recurrent meningioma.

  719. [05/02/2006] Randomized, double-blind, placebo-controlled trial of marimastat in glioblastoma multiforme patients following surgery and irradiation( bigstar).

  720. [05/01/2006] Fluorescence-Guided Surgery Improves Glioma Survival

  721. [04/25/2006] Technology Could Bring Safer Brain Tumor Surgery

  722. [04/25/2006] NEOPHARM`S CINTREDEKIN BESUDOTOX WELL-TOLERATED IN NEWLY DIAGNOSED MALIGNANT GLIOMA PATIENTS

  723. [04/21/2006] MDS to produce brain cancer drug

  724. [04/19/2006] Dr Susan C. Pannullo to lecture on 2 brain tumor topics at the Association of Neurological Surgeons annual meeting in San Francisco next week

  725. [04/18/2006] BrainLAB iPlan(R) Flow Software Opens New Avenues for Delivering Drugs to the Brain Cooperative project between the German National Ministry for Education and Research and American National Institutes of Health leads to improved clinical results

  726. [04/18/2006] Technique Could Speed New Medulloblastoma Drugs

  727. [04/18/2006] Increased concentrations of transforming growth factor beta1 and beta2 in the plasma of patients with glioblastoma.

  728. [04/07/2006] Cancerous vs. healthy cells- Researchers identify the road to success Studies determine best route for targeted therapies. NF-kB as a Therapeutic Target in Malignant Gliomas: Abstract No. 1506

  729. [04/05/2006] A new hope for brain tumor patients

  730. [04/03/2006] Cancer centers add MRIs to ORs, expand proton therapy

  731. [04/03/2006] Long Island, NY Support group meeting Thursday, April 6

  732. [04/03/2006] Innovative Brain Tumor Program delivers immediate access To Care

  733. [03/30/2006] Carmustine Implant Improves Malignant Glioma Survival

  734. [03/29/2006] Radiotherapy Advance Points Way To Noninvasive Brain Cancer Treatment

  735. [03/21/2006] Recent advances in the treatment of malignant astrocytoma.

  736. [03/21/2006] Diagnosis and treatment of recurrent high-grade astrocytoma.

  737. [03/21/2006] Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.

  738. [03/21/2006] OR-Live.com Presents: Memorial Hermann The Woodlands` Live Webcast to Feature Brain Tumor Resection -- Surgeon Uses Advanced Intraoperative Guided System

  739. [03/20/2006] (PRN) Presbyterian Hospital of Dallas to Make Advanced Neurosurgical Operating Room Technology Available for its Patients

  740. [03/16/2006] Laureate Pharma and Bradmer Pharmaceuticals Announce Their Development and Manufacturing Agreement on a Therapeutic Monoclonal Antibody Product for Treatment of Brain Cancer

  741. [03/14/2006] Salvage chemotherapy with cyclophosphamide for recurrent temozolomide-refractory anaplastic astrocytoma.

  742. [03/08/2006] Gliadel(R) Wafer Demonstrates Long-Term Survival Benefit for Patients with High-Grade Malignant Gliomas

  743. [03/07/2006] Adding Chloroquine to Conventional Chemotherapy and Radiotherapy for Glioblastoma Multiforme

  744. [02/27/2006] Do not deny these patients a longer life

  745. [02/21/2006] Survival rates and patterns of care for patients diagnosed with supratentorial low-grade gliomas: data from the SEER program, 1973-2001.

  746. [02/21/2006] Researchers at UPCI Studying New Approach to Attacking Brain Tumors

  747. [02/16/2006] Antibody for brain tumors boosts survival in mice

  748. [02/12/2006] In fight for life, insurer no help

  749. [02/09/2006] Woman to try personalized vaccine

  750. [01/30/2006] HEALING HIMSELF

  751. [01/23/2006] Experimental treatment for brain tumors tested in Valhalla

  752. [01/15/2006] UVa doctors work to improve deadly tumor treatment

  753. [01/11/2006] Researchers at Vanderbilt-Ingram Cancer Center uncover clue to explain invasive brain tumors

  754. [01/05/2006] Virus-Drug Combination May Have Synergistic Effect Against Glioblastoma

  755. [01/05/2006] Salvage Radioimmunotherapy With Murine Iodine-131–Labeled Antitenascin Monoclonal Antibody 81C6 for Patients With Recurrent Primary and Metastatic Malignant Brain Tumors: Phase II Study Results

  756. [12/26/2005] Gamma knife surgery for low-grade gliomas.

  757. [12/22/2005] Study: New brain tumor therapy

  758. [12/21/2005] Health Alert: Brain tumor vaccine

  759. [12/16/2005] Cancer Vaccine Treatments Promising for Prostate and Brain Tumors

  760. [12/12/2005] Breakthrough Cancer Treatment Approved in Scotland but Still not Available to all on NHS

  761. [12/10/2005] Hearing Loss From Chemotherapy Underestimated Say Researchers At Oregon Health and Sciences University

  762. [12/08/2005] WINGS CORNER: Players pay visit to Children`s Hospital

  763. [12/07/2005] A phase II window trial of procarbazine and topotecan in children with high-grade glioma: a report from the children`s oncology group.

  764. [12/07/2005] Study suggests a way to eliminate glioblastoma

  765. [12/02/2005] Meningioma resection in the elderly: nationwide inpatient sample, 1998-2002.

  766. [12/02/2005] Stereotactic interstitial radiosurgery for cerebral metastases.

  767. [12/02/2005] Frame-based stereotactic biopsy remains an important diagnostic tool with distinct advantages over frameless stereotactic biopsy.

  768. [12/02/2005] Long-term survivors after gamma knife radiosurgery for brain metastases.

  769. [12/01/2005] Cedara Software Showcases Innovative New Cancer Diagnosis and Treatment Technologies at RSNA 2005 -- Cedara introduces a works-in-progress suite of applications named Cedara OncologyWorks(TM) to the radiology community

  770. [12/01/2005] New Treatment for Specialized Brain Tumor Affecting 1 in 3,500 Preserves Hearing for First Time; New Surgery Expected to Replace Common Procedure That Renders Patients Deaf

  771. [11/21/2005] First Patient Enrolled in Investigator-Sponsored Phase 1/2 Trial of Antigenics` Oncophage Cancer Vaccine in Glioma

  772. [11/16/2005] Innovative research set to push boundaries of cancer care

  773. [11/16/2005] Rapamycin Analog AP23573 Crosses Blood-Brain Barrier and Targets Glioma: Presented at AACR-NCI-EORTC

  774. [11/10/2005] FONAR Ships World`s First Room-Size MR Scanner to the Nuffield Orthopaedic Centre in Oxford, England

  775. [11/02/2005] Cancer Chemosensitivity Testing

  776. [11/01/2005] Temozolomide Improves Survival in Glioma: Presented at ECCO

  777. [10/28/2005] Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.

  778. [10/28/2005] Adjuvant gamma knife stereotactic radiosurgery at the time of tumor progression potentially improves survival for patients with glioblastoma multiforme.

  779. [10/28/2005] Serial diffusion-weighted magnetic resonance imaging in cases of glioma: distinguishing tumor recurrence from postresection injury.

  780. [10/26/2005] New approach to chemo: Continuous, lower doses

  781. [10/23/2005] The Efficacy of Postoperative Ondansetron (Zofran®) Orally Disintegrating Tablets for Preventing Nausea and Vomiting After Acoustic Neuroma Surgery

  782. [10/19/2005] NeoPharm Investigators Present Preliminary Phase I Data of Cintredekin Besudotox in the Treatment of Malignant Glioma at Initial Diagnosis

  783. [10/19/2005] Brain cancer patients fight an unseen enemy Advice and updated information offered at recent area conference

  784. [10/19/2005] Oncolytics Biotech Inc. Ends Patient Treatment in Canadian Phase I Recurrent Malignant Glioma Clinical Trial

  785. [10/18/2005] Autumn Birth Linked to Childhood Brain Cancer

  786. [10/18/2005] O6–BG May Help Re-Sensitize Cancer Cells to Temodar® in Brain Cancer

  787. [10/05/2005] Arachnoid cysts cause cognitive deficits that improve after surgery.

  788. [10/05/2005] Prolonged oral hydroxyurea and concurrent 3d-conformal radiation in patients with progressive or recurrent meningioma: results of a pilot study.

  789. [10/05/2005] Considerations on the Role of Chemotherapy and Modern Radiotherapy in the Treatment of Childhood Low Grade Glioma.

  790. [10/03/2005] Minimally Invasive Brain Tumor Surgery Gaining Ground

  791. [10/03/2005] Doctors at Providence Hospital Use Image-Guided Stereotactic Intensity-Modulated Radiotherapy to Target Spinal Tumors While Protecting Spinal Cord

  792. [09/27/2005] Active immunotherapy for advanced intracranial murine tumors by using dendritic cell-tumor cell fusion vaccines.

  793. [09/27/2005] Linear accelerator surgery for meningiomas.

  794. [09/27/2005] Case-control study of stereotactic radiosurgery for recurrent glioblastoma multiforme.

  795. [09/23/2005] Columbia scientists develop cancer terminator viruses - Results advance quest for viral-based therapies for cancer

  796. [09/22/2005] Fractionated Stereotactic Radiation Therapy Safely and Effectively Manages Acoustic Neuroma

  797. [09/21/2005] Northwest Biotherapeutics Announces Clinical Advisory Board for Brain Cancer Program

  798. [09/21/2005] North Shore-LIJ`s (NY) Establishes Neuro-Oncology Program

  799. [09/15/2005] Radiosurgery in the treatment of malignant gliomas: the University of Florida experience.

  800. [09/15/2005] Diagnosis and treatment of atypical and anaplastic meningiomas: a review.

  801. [09/08/2005] Intracavitary Chemotherapy (paclitaxel/Carboplatin Liquid Crystalline Cubic Phases) for Recurrent Glioblastoma - Clinical Observations.

  802. [09/08/2005] Marital status, treatment, and survival in patients with glioblastoma multiforme.

  803. [09/05/2005] UCSF Team Advances Probe of Neural Stem Cell-Brain Tumor Link

  804. [08/29/2005] Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo.

  805. [08/29/2005] Homeopathic Effectiveness

  806. [08/29/2005] Peregrine Pharmaceuticals and New Approaches to Brain Tumor Therapy (NABTT) Consortium Initiate Cotara(R) Brain Cancer Trial

  807. [08/28/2005] Radio-guided Neurosurgery for treatment of Brain cancer

  808. [08/20/2005] Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant glioma.

  809. [08/19/2005] Early Radiation Improves Progression-Free Survival in Low-Grade Brain Cancer

  810. [08/16/2005] Recurrence of meningiomas.

  811. [08/15/2005] Latest-generation Leksell Gamma Knife(R) Offers Enhanced Treatment Options for Brain Tumors and Disorders

  812. [08/15/2005] Researchers find that combined gene therapy eliminates glioblastoma multiforme in lab studies

  813. [07/27/2005] Craniotomy for meningioma in the United States between 1988 and 2000: decreasing rate of mortality and the effect of provider caseload.

  814. [07/27/2005] Standard-risk medulloblastoma treated by adjuvant chemotherapy followed by reduced-dose craniospinal radiation therapy: a French Society of Pediatric Oncology Study.

  815. [07/26/2005] BrainLAB Launches Automated Treatment Planning Capability for Greater Consistency in Non-Invasive Stereotactic Brain Tumor Treatments

  816. [07/21/2005] MGI PHARMA to Acquire Guilford Pharmaceuticals

  817. [07/21/2005] Blood vessel drugs halt cancer growth

  818. [07/12/2005] Functional magnetic resonance imaging-guided resection of low-grade gliomas.

  819. [07/12/2005] Human interferon beta, nimustine hydrochloride, and radiation therapy in the treatment of newly diagnosed malignant astrocytomas.

  820. [07/05/2005] Temozolomide-induced partial response in a patient with primary diffuse leptomeningeal gliomatosis.

  821. [07/05/2005] Persistent cognitive dysfunction secondary to cerebellar injury in patients treated for posterior fossa tumors in childhood.

  822. [06/27/2005] NEOPHARM, INC ANNOUNCES PRECISE TRIAL UPDATE

  823. [06/23/2005] New hope for brain cancer patients

  824. [06/17/2005] Collaboration leads to stem cell research program - A university, a hospital and a physician`s practice have come together to establish a program in Memphis for analyzing brain cancer using adult stem cells.

  825. [06/15/2005] Why are systemic glioblastoma metastases rare? Systemic and cerebral growth of mouse glioblastoma.

  826. [06/15/2005] A phase I trial of surgery, Gliadel wafer implantation, and immediate postoperative carboplatin in combination with radiation therapy for primary anaplastic astrocytoma or glioblastoma multiforme.

  827. [06/15/2005] P450 enzyme inducing and non-enzyme inducing antiepileptics in glioblastoma patients treated with standard chemotherapy.

  828. [06/10/2005] Safety and feasibility of convection-enhanced delivery of Cotara for the treatment of malignant glioma: initial experience in 51 patients.

  829. [06/10/2005] Intratumoral delivery of mitoxantrone in association with 90-Y radioimmunotherapy (RIT) in recurrent glioblastoma.

  830. [06/03/2005] Brain cancer drug in 2nd phase of tests

  831. [06/02/2005] Gene Signature Could Revolutionize Cancer CareDiscovery should help doctors tailor treatment to specific tumor type.

  832. [06/02/2005] Gene Variant Predicts Brain Tumor Survival Enzyme Related to Chromosome Length Holds the Key

  833. [06/01/2005] Clinical Data Published in Neurosurgery Shows Peregrine Pharmaceuticals` Cotara(R) Holds Promise for Treating Brain Cancer

  834. [05/31/2005] Is gross-total resection sufficient treatment for posterior fossa ependymomas?

  835. [05/31/2005] Stereotactic radiosurgery for pituitary adenomas: an intermediate review of its safety, efficacy, and role in the neurosurgical treatment armamentarium.

  836. [05/27/2005] The Dilemma: Surgery or Radiation for Acoustic Neuroma Brain Tumors?

  837. [05/26/2005] NeoPharm: brain tumor agent may struggle to overtake Temodar NeoPharm has announced a review of safety data for the ongoing PRECISE trial.

  838. [05/20/2005] YM BioSciences and CIMAB achieve clinical milestone - Data for TheraCIM h-R3 in High Grade Malignant Glioma presented at ASCO 2005 -

  839. [05/20/2005] Mixed neuronal-glial tumor of the fourth ventricle and successful treatment of postoperative mutism with bromocriptine: case report.

  840. [05/18/2005] Mayo Clinic Researchers Develop New Treatment For Incurable Recurring Form Of Adult Brain Cancer

  841. [05/17/2005] Guilford Pharmaceuticals Announces Promising Results at ASCO in Study of Newly Diagnosed High Grade Malignant Glioma

  842. [05/11/2005] Prognostic significance of intracranial dissemination of glioblastoma multiforme in adults.

  843. [05/07/2005] Viruses May One Day Help Treat Brain Tumors

  844. [05/05/2005] Time From Treatment to Subsequent Diagnosis of Brain Metastases in Stage III Non-Small-Cell Lung Cancer: A Retrospective Review by the Southwest Oncology Group.

  845. [05/05/2005] Antisoma Reviews Portfolio: Drops AS1405 to Accelerate AS1411 - [Editor`s note: Brain tumor trial to close immediatley!]

  846. [05/04/2005] Ark Therapeutics Group plc: Ark Strengthens International Patent Position on Leading Products

  847. [05/03/2005] History of Chickenpox and Shingles and Prevalence of Antibodies to Varicella-Zoster Virus and Three Other Herpesviruses among Adults with Glioma and Controls

  848. [04/30/2005] Brain surgery with no incision: Fairview-University offers the Gamma Knife New technology makes outpatient brain surgery a reality

  849. [04/30/2005] NeoPharm Investigators to Present Results of Cintredekin Besudotox Multicenter Phase I Clinical Studies at the World Federation of Neuro-Oncology Meeting

  850. [04/30/2005] Study Comparing Radiation Therapy and Surgery for Acoustic Neuroma Patients Urged

  851. [04/26/2005] ~~~Together in Hope: A Conference for Brain Tumor Patients and their Families~~~

  852. [04/26/2005] HEALTH CARE ADVOCATE COMMEMORATES NATIONAL BRAIN TUMOR AWARENESS WEEK

  853. [04/26/2005] Is older age associated with a worse prognosis due to different patterns of care? A long-term study of 1346 patients with glioblastomas or brain metastases.

  854. [04/19/2005] Improving malignant glioma survival rates

  855. [04/18/2005] Scientist works to reduce side effects of radiation therapy

  856. [04/18/2005] Correlation between Patient Outcomes, Care by New Interns and Residents Libraries (in Pediatric Neurosurgery )

  857. [04/13/2005] Scientists identify protein that controls cancer cells

  858. [04/12/2005] An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor.

  859. [04/09/2005] A whole town`s rooting for him - With help from a Bronx surgical team and best wishes from his hometown in Northern Ireland, a boy has surgery to remove a rare brain tumor

  860. [04/09/2005] New Sealant Protects Brain After Surgery

  861. [04/07/2005] Viruses May One Day Help Treat Brain Tumors

  862. [04/06/2005] M.D. Anderson and Baylor will turn neurosurgery programs into one

  863. [04/02/2005] Autumn Birth Linked to Childhood Brain Cancer

  864. [04/02/2005] Cancer Patients Got Extra Radiation

  865. [03/30/2005] Brain surgery with no incision: Fairview-University offers the Gamma Knife

  866. [03/21/2005] Wake Forest University Baptist Medical Center Scientist works on innovative treatments for brain tumors

  867. [03/21/2005] Brain Tumor With Dismal Prognosis In Infants Can Be Cured In Older Children

  868. [03/19/2005] Medical center first hospital in region to offer internal radiation therapy treatment for brain cancer

  869. [03/10/2005] Resection of brain metastases previously treated with stereotactic radiosurgery.

  870. [03/10/2005] Neuroradiographic changes following convection-enhanced delivery of the recombinant cytotoxin interleukin 13-PE38QQR for recurrent malignant glioma.

  871. [03/10/2005] Limited efficacy of gene transfer in herpes simplex virus-thymidine kinase/ganciclovir gene therapy for brain tumors.

  872. [03/10/2005] Inotek Pharmaceuticals Announces Commencement of Enrollment in Phase 1b/2a Trial for Glioblastoma Multiforme

  873. [03/10/2005] New hope against brain tumors

  874. [03/03/2005] Brain tumor with dismal prognosis in infants can be cured in older children

  875. [03/03/2005] Scorpion venom takes on tumors A protein from the poison helps deliver radioactive molecules to cancer cells.

  876. [03/02/2005] Parents face choice in treating childhood cancer

  877. [03/01/2005] Myriad Initiates Phase 1 Trial of MPC-6827 in Metastatic Brain Cancer

  878. [02/23/2005] High-dose chemotherapy with autologous stem cell rescue for children with high risk and recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors.

  879. [02/23/2005] Parathyroid Adenoma Linked to Primary CNS Tumors

  880. [02/15/2005] Radiation dosimetry of (131)I-chlorotoxin for targeted radiotherapy in glioma-bearing mice.

  881. [02/15/2005] Survival rates in patients with low-grade glioma after intraoperative magnetic resonance image guidance.

  882. [02/11/2005] Garth Brooks to play benefit in FW

  883. [02/08/2005] OR-Live.com presents: Live Brain Cancer Surgery: Brain Tumor Removal With GliaSite Radiation Therapy TODAY at 5pm, EST!

  884. [02/02/2005] A vaccine for brain tumors

  885. [02/02/2005] Troubling Variations In Brain Cancer Treatment Study Shows Choices Affect Patient Survival

  886. [02/02/2005] Patterns of Care for Adults With Newly Diagnosed Malignant Glioma

  887. [02/01/2005] The relationship between peritumoral brain edema and the expression of vascular endothelial growth factor and its receptors in intracranial meningiomas.

  888. [02/01/2005] Phase II study of temozolomide and cisplatin as primary treatment prior to radiotherapy in newly diagnosed glioblastoma multiforme patients with measurable disease. A study of the Spanish Medical Neuro-Oncology Group (GENOM).

  889. [02/01/2005] Molecular mechanisms of glioma cell migration and invasion.

  890. [02/01/2005] Genetic and hypoxic regulation of angiogenesis in gliomas.

  891. [01/29/2005] OR-Live.com presents: Live Brain Cancer Surgery: Brain Tumor Removal With GliaSite Radiation Therapy

  892. [01/27/2005] OHSU study: Protein stops growth of brain tumor - Herstatin blocks signaling inside cells that leads to deadly glioblastoma growth

  893. [01/25/2005] Columbia research lifts major hurdle to gene therapy for cancer

  894. [01/25/2005] Schering-Plough Corporation (NYSE: SGP) today reported financial results for the 2004 fourth quarter and full year.

  895. [01/22/2005] Peregrine and New Approaches to Brain Tumor Therapy (NABTT) Consortium Receive Approval for Cotara(R) Brain Cancer Protocol

  896. [01/21/2005] Poway Woman First To Try Experimental Brain Cancer Treatment

  897. [01/20/2005] Students to Hear Young Neurosurgeon Role Model, See Brain Injury Booth

  898. [01/18/2005] Fractional anisotropy value by diffusion tensor magnetic resonance imaging as a predictor of cell density and proliferation activity of glioblastomas.

  899. [01/17/2005] Doctors at Fort Lauderdale convention honor neurosurgeon recovering from crash

  900. [01/17/2005] Operating on the Inoperable Brain

  901. [01/12/2005] Trestle`s MedMicro Becomes First Remote-Controlled Microscope Installed in Denver`s The Children`s Hospital

  902. [01/12/2005] Operating on the inoperable brain

  903. [01/11/2005] OR-Live.com presents: Live Brain Cancer Surgery: Brain Tumor Removal With GliaSite Radiation Therapy

  904. [01/10/2005] Preoperative and Intraoperative Diffusion Tensor Imaging-based Fiber Tracking in Glioma Surgery.

  905. [01/04/2005] Easier Brain Surgery [Editor`s note - this is a correction - I left the story out last time]

  906. [01/03/2005] New weapons target deadly brain cancer

  907. [01/03/2005] Easier Brain Surgery

  908. [12/28/2004] Report Claims Some Cancer Patients Being Required to Buy Their Own Drugs

  909. [12/28/2004] The human glutathione S-transferase P1 protein is phosphorylated and its metabolic function enhanced by the Ser/Thr protein kinases, cAMP-dependent protein kinase and protein kinase C, in glioblastoma cells.

  910. [12/21/2004] Protein Delivered Via Genetically Engineered Virus Slowed Glioblasoma Multiforme Growth

  911. [12/20/2004] Spinal lesions treated with Novalis shaped beam intensity-modulated radiosurgery and stereotactic radiotherapy.

  912. [12/20/2004] Inotek Pharmaceuticals Announces Commencement of Enrollment in Phase 2 Trial on Lead Compound

  913. [12/17/2004] Pfizer Says Celebrex Increases Heart Risk

  914. [12/16/2004] Protein Delivered Via Genetically Engineered Virus Slowed Glioblasoma Multiforme Growth

  915. [12/15/2004] Novel Israeli treatment zaps tumors using light and pigment

  916. [12/14/2004] Ecopia`s Brain Tumour Compound, ECO-4601, Reaches Important Threshold Toward Clinical Trials

  917. [12/13/2004] Health Alert: Anti-seizure device

  918. [12/07/2004] TransMolecular Successfully Completes Phase I/II Clinical Trial With its Targeted Oncology Therapeutic

  919. [12/06/2004] Protein Upped Immune Cells, Slowed Growth of Glioblastoma Multiforme

  920. [12/06/2004] Silencing of Monocarboxylate Transporters via Small Interfering Ribonucleic Acid Inhibits Glycolysis and Induces Cell Death in Malignant Glioma: An in Vitro Study.

  921. [12/06/2004] Second-Line Chemotherapy With Irinotecan Plus Carmustine in Glioblastoma Recurrent or Progressive After First-Line Temozolomide Chemotherapy: A Phase II Study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).

  922. [12/06/2004] Fighting Cancerous Cells

  923. [11/25/2004] Invasive phenotype observed in 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant sublines of 9L rat glioma cells: a tumor model mimicking a recurrent malignant glioma.

  924. [11/24/2004] Anti-Cancer Vaccine Doubles Time-To-Disease Progression and Increases Survival in Phase I Brain Cancer Trial

  925. [11/23/2004] NEW AND UPDATED IL13-PE38QQR PHASE I/II DATA PRESENTED AT THE 9TH ANNUAL MEETING OF THE SOCIETY FOR NEURO-ONCOLOGY

  926. [11/23/2004] Guilford Pharmaceuticals Inc. (GLFD) Presents New GLIADEL(R) Wafer Data At The Society For Neuro-Oncology Annual Meeting

  927. [11/23/2004] Dr. S. R. Burzynski Presents Preliminary Research On Antineoplastons A10 and AS2-1 For Treatment of Deadly Brain Tumors to the Society For Neuro-Oncology

  928. [11/19/2004] Positive Results Reported in Phase II Study of Cervene - TP-38 - To Treat Brain Cancer; Data Presented at Society for Neuro-Oncology Meeting in Toronto

  929. [11/16/2004] On-line flow cytometry for real-time surgical guidance.

  930. [11/16/2004] Post-Therapy Damage Seen on MRI Scans of Medulloblastoma Patients Can Be Mistaken for New Tumors

  931. [11/14/2004] Brain tumour detection advances

  932. [11/11/2004] New gene target found for common brain tumors in children

  933. [11/11/2004] Dexamethasone mediated inhibition of local IL-2 immunotherapy is dose dependent in experimental brain tumors.

  934. [11/11/2004] Intracranial meningiomas developing at long intervals following low-dose X-ray irradiation of the head.

  935. [11/09/2004] TransMolecular Obtains Patent for Key Biological Target Involved in Chronic Pain

  936. [11/09/2004] Peregrine Pharmaceuticals and New Approaches to Brain Tumor Therapy (NABTT) Consortium Enter Collaboration to Treat Brain Cancer Patients

  937. [11/02/2004] Loss of Heterozygosity Analysis of Benign, Atypical, and Anaplastic Meningiomas.

  938. [10/28/2004] Surgery and adjuvant dendritic cell-based tumour vaccination for patients with relapsed malignant glioma, a feasibility study

  939. [10/28/2004] Two drugs for a hitherto fatal brain cancer are giving patients a new lease on life.

  940. [10/21/2004] Newcastle Disease Virus

  941. [10/21/2004] Data on GliaSite Radiation Therapy System for Recurrent Brain Tumors Presented at Neurological Surgeons Meeting

  942. [10/20/2004] How effective is BCNU in recurrent glioblastoma in the modern era? A phase II trial.

  943. [10/20/2004] Surgery and adjuvant dendritic cell-based tumour vaccination for patients with relapsed malignant glioma, a feasibility study.

  944. [10/15/2004] Stem cell research offers new hope for Brain tumor patients - Californians to decide on Stem Cell Initiative in November

  945. [10/15/2004] Scientific Illiteracy in the U.S. [Editor`s Note: Also information on a special program at Cedars Sinai for science students]

  946. [10/12/2004] Convection-enhanced delivery of tumor necrosis factor-related apoptosis-inducing ligand with systemic administration of temozolomide prolongs survival in an intracranial glioblastoma xenograft model.

  947. [10/05/2004] Feasibility of Radiosurgery for Malignant Brain Tumors in Infants by Use of Image-guided Robotic Radiosurgery: Preliminary Report.

  948. [10/05/2004] Antitumor Vaccination of Patients With Glioblastoma Multiforme: A Pilot Study to Assess Feasibility, Safety, and Clinical Benefit.

  949. [10/05/2004] Delivery of interferon-alpha transfected dendritic cells into central nervous system tumors enhances the antitumor efficacy of peripheral peptide-based vaccines.

  950. [10/04/2004] First Data on GliaSite Radiation Therapy System as Primary Treatment for Metastatic Brain Cancer Presented at Radiation Oncology Meeting

  951. [10/04/2004] A cure for the rhythm blues A computerized metronome helps speed healing for brain-injury patients who have difficulty focusing, memory trouble or poor balance.

  952. [10/03/2004] Benefit for brain tumor foundation - Residents organize comedy night to raise awareness

  953. [09/28/2004] Heat -sensing camera may see brain tumor remnants

  954. [09/27/2004] Phase II Trial of Temozolomide in Patients With Progressive Low-Grade Glioma

  955. [09/27/2004] Guilford Pharmaceuticals Announces Orphan Drug Designation for GLIADEL(R) Wafer

  956. [09/26/2004] Imaging technology aided doctors during brain surgery

  957. [09/26/2004] Medical privacy law said to be chilling cancer studies Scientists fight for fast access to patient files

  958. [09/24/2004] Alternative treatment destroyed brain tumour

  959. [09/23/2004] Ecopia`s Lead Cancer Compound Shown to Cross Blood-Brain Barrier

  960. [09/23/2004] R.I. woman shares struggle with brain tumor

  961. [09/22/2004] Transient local response and persistent tumor control in a child with recurrent malignant glioma: treatment with combination therapy including dendritic cell therapy. Case report.

  962. [09/21/2004] Choroid plexus tumors: a review of 28-year experience.

  963. [09/21/2004] Decoupling the Control of Brain Cancer Cells

  964. [09/21/2004] Evidence for a clinically distinct new subtype of grade II astrocytomas in patients with long-term epilepsy.

  965. [09/21/2004] Diagnosis and management of pineocytomas.

  966. [09/21/2004] Gene Expression Profiling of Gliomas Strongly Predicts Survival.

  967. [09/20/2004] Targeted therapy knocks out pediatric brain cancer in mice

  968. [09/16/2004] September is Childhood Cancer Awareness Month - Local group picks September 30th, as Pediatric Brain Tumor Awareness Day

  969. [09/16/2004] Guilford Pharmaceuticals Receives European Marketing Authorization for Expanded Use of GLIADEL(R) Wafer - GLIADEL(R) Approved to Treat Newly-Diagnosed Patients with Malignant Glioma

  970. [09/16/2004] Proton magnetic resonance spectroscopy imaging in the evaluation of patients undergoing gamma knife surgery for Grade IV glioma.

  971. [09/16/2004] Oncolytic Viruses: Clinical Applications as Vectors for the Treatment of Malignant Gliomas (Full text available)

  972. [09/16/2004] Phase II Study of Concurrent Continuous Temozolomide (TMZ) and Tamoxifen (TMX) for Recurrent Malignant Astrocytic Gliomas

  973. [09/16/2004] Decoupling the control of brain cancer cells to find better treatments

  974. [09/16/2004] Brain cancer rate in normal range, study finds

  975. [09/10/2004] Intramedullary spinal cord astrocytomas in children

  976. [09/07/2004] Senators family feels effects of medical crisis

  977. [09/07/2004] Survival trends in elderly patients with glioblastoma multiforme: resective surgery, radiation, and chemotherapy.

  978. [09/07/2004] CyberKnife frameless stereotactic radiosurgery for spinal lesions: clinical experience in 125 cases.

  979. [09/07/2004] The role of radiation therapy after surgical resection of nonfunctional pituitary macroadenomas.

  980. [09/07/2004] Integration of biochemical images of a tumor into frameless stereotaxy achieved using a magnetic resonance imaging/magnetic resonance spectroscopy hybrid data set.

  981. [09/05/2004] Chemotherapy Experts Refute ASCO Recommendations on Use of Drug Sensitivity and Resistance Assays

  982. [09/01/2004] Peregrine Pharmaceuticals Extends its Platform of Novel Anti-Cancer Technologies

  983. [08/31/2004] Gamma knife radiosurgery for benign cavernous sinus tumors: quantitative analysis of treatment outcomes.

  984. [08/30/2004] Robust infectivity and replication of Delta-24 adenovirus induce cell death in human medulloblastoma

  985. [08/24/2004] Hospital now offers improved CT scanner

  986. [08/24/2004] Results of a phase II upfront window of pharmacokinetically guided topotecan in high-risk medulloblastoma and supratentorial primitive neuroectodermal tumor.

  987. [08/24/2004] Association between laminin-8 and glial tumor grade, recurrence, and patient survival.

  988. [08/22/2004] Initial treatment of melanoma brain metastases using gamma knife radiosurgery: an evaluation of efficacy and toxicity.

  989. [08/14/2004] Cannabis may block growth of brain cancer

  990. [08/14/2004] Radiosurgery as Primary Management for Meningiomas Extending into the Internal Auditory Canal

  991. [08/12/2004] A virus for the brain [Scroll down to the section on brain]

  992. [08/10/2004] Associations among magnetic resonance spectroscopy, apparent diffusion coefficients, and image-guided histopathology with special attention to radiation necrosis.

  993. [08/10/2004] Initial treatment of melanoma brain metastases using gamma knife radiosurgery

  994. [08/06/2004] Precision Treatment - Advanced radiation therapy machine treats small areas in critical spots

  995. [08/06/2004] Preliminary visual field preservation after staged CyberKnife radiosurgery for perioptic lesions.

  996. [08/06/2004] Initial chemotherapy in gliomatosis cerebri.

  997. [08/05/2004] 3 D irradiation of brain cancer in children spares IQ, memory, other cognitive functions

  998. [08/05/2004] Molecular therapeutics advance fight against brain cancer

  999. [08/05/2004] Smart drug that targets cancer cells in the brain following removal of a tumor

  1000. [08/05/2004] NEOPHARM INITIATES PHASE I STUDY OF IL13-PE38QQR IN PATIENTS AT INITIAL DIAGNOSIS OF MALIGNANT GLIOMA

  1001. [08/03/2004] GUILFORD PHARMACEUTICALS GLIADEL WAFER ASSIGNED NEW DRG DESIGNATION

  1002. [08/01/2004] Study shows that fluorescence spectroscopy can distinguish brain tumor from normal tissue

  1003. [07/27/2004] Volumetric Assessment of Glioma Removal by Intraoperative High-field Magnetic Resonance Imaging.

  1004. [07/27/2004] Temozolomide in paediatric high-grade glioma: a key for combination therapy?

  1005. [07/26/2004] Identification of cell surface markers and astrocytoma associated genes

  1006. [07/25/2004] Correlation of the response of recurrent malignant gliomas treated with interferon alpha with tumor interferon alpha gene content.

  1007. [07/24/2004] Drug prevents chemotherapy-induced hearing loss, study finds

  1008. [07/24/2004] Treatment of Intracerebral Neoplasia and Neoplastic Meningitis with Regional Delivery of Oncolytic Recombinant Poliovirus

  1009. [07/20/2004] Supratentorial gangliogliomas: histopathologic grading and tumor recurrence in 184 patients with a median follow-up of 8 years.

  1010. [07/20/2004] Cyberknife Arrives at NJ`s Overlook Hospital; First in Northeast to Offer New Robotic Technology to Treat Inoperable Brain, Spine Tumors with Incision-Free `Surgery`

  1011. [07/18/2004] A blemish in diagnostic imaging

  1012. [07/17/2004] NASA Infrared Camera Helps Surgeons Map Brain Tumors

  1013. [07/17/2004] Brain Cancer Vaccine Shows Promising Findings In Early Research At UCLA`s Jonsson Cancer Center

  1014. [07/17/2004] Chemo wafers used to treat brain tumor directly

  1015. [07/15/2004] EXPERIMENTAL VACCINE - New way to fight brain cancer

  1016. [07/13/2004] Operating on brain gets safer

  1017. [07/12/2004] Abbott Labs Intends to Submit New Drug Application for Xinlay™ (Atrasentan) for men with metastatic, hormone–refractory prostate cancer [Editor`s Note: mentions brain tumors also]

  1018. [07/10/2004] Adding Temozolomide (Temodar®) to Radiation Increases Survival in Glioblastoma Multiforme

  1019. [07/08/2004] Cooperative function of Chk1 and p38 pathways in activating G2 arrest following exposure to temozolomide.

  1020. [07/08/2004] Results of contemporary surgical management of radiation necrosis using frameless stereotaxis and intraoperative magnetic resonance imaging.

  1021. [07/08/2004] TransMID drug adheres to cells in brain tumors

  1022. [07/01/2004] Geron Announces Publication of Data on GRN163, a Telomerase Inhibitor, in Animal Models of Human Brain Tumors

  1023. [06/23/2004] Specialized Tumor Treatment Comes To Omaha - Nebraska Medical Center Introduces Novalis Radiation

  1024. [06/23/2004] Brain tumor gene target found

  1025. [06/22/2004] Recombinant vesicular stomatitis virus vectors as oncolytic agents in the treatment of high-grade gliomas in an organotypic brain tissue slice-glioma coculture model.

  1026. [06/22/2004] Journal Cancer: Protein shift predicts brain cancer grade, recurrence and patient survival

  1027. [06/17/2004] Centers for Medicare and Medicaid Services Drug reimbursement won’t help hospitals Medicare puts brain-cancer drug at disincentive

  1028. [06/15/2004] SciClone`s ZADAXIN Shows Promising Effects in Treating Brain Cancer in Animal Model Study

  1029. [06/11/2004] Public Comment Sought on Proposed Rule for Medicare Payment for New Brain Tumor Treatment

  1030. [06/08/2004] Drug treatment is first major improvement in brain cancer in decades

  1031. [06/08/2004] Temozolomide combined with radiation as first-line treatment in primary glioblastoma multiforme: Phase I/II-study.

  1032. [06/08/2004] Second line BCNU plus CPT-11 chemotherapy in recurrent glioblastoma (GBM): Phase II study of GICNO (Italian Neuro-Oncology Group).

  1033. [06/08/2004] Phase II study of ZD1839 in patients with newly diagnosed grade 4 astrocytoma.

  1034. [06/08/2004] One week on/one week off regimen of temozolomide for recurrent glioblastoma: A phase II study.

  1035. [06/08/2004] Multicentre phase II study of imatinib mesylate in patients with recurrent glioblastoma: An EORTC: NDDG/BTG Intergroup Study.

  1036. [06/08/2004] Microvessel density predicts behavior in pediatric optic pathway/hypothalamic gliomas.

  1037. [06/08/2004] Methylated tumor-specific DNA as a plasma biomarker in patients with glioma.

  1038. [06/08/2004] Intensity modulated radiotherapy in high grade gliomas: Clinical and dosimetric results.

  1039. [06/08/2004] Imatinib (STI 571) is active in patients (PTS) with high-grade gliomas progressing on standard therapy.

  1040. [06/08/2004] An intergroup randomized controlled clinical trial (RCT) of chemotherapy plus radiation (RT) versus RT alone for pure and mixed anaplastic oligodendrogliomas: Initial report of RTOG 94-02.

  1041. [06/08/2004] Safety and efficacy of high-dose chemotherapy with autologous stem cell transplantation for patients with malignant astrocytomas.

  1042. [06/06/2004] Resveratrol suppresses the angiogenesis and tumor growth of gliomas in rats.

  1043. [06/01/2004] The early effects of radiotherapy on intellectual and cognitive functioning in patients with frontal brain tumours: the use of a new neuropsychological methodology.

  1044. [05/18/2004] Evaluation of the response of metastatic brain tumors to stereotactic radiosurgery by proton magnetic resonance spectroscopy, 201TlCl single-photon emission computerized tomography, and gadolinium-enhanced magnetic resonance imaging.

  1045. [05/18/2004] Gamma knife surgery in the management of brain metastases from lung carcinoma: a retrospective analysis of survival, local tumor control, and freedom from new brain metastasis.

  1046. [05/18/2004] Role of estrogen receptor-related antigen in initiating the growth of human glioma cells.

  1047. [05/18/2004] Posterior fossa metastases: risk of leptomeningeal disease when treated with stereotactic radiosurgery compared to surgery.

  1048. [05/17/2004] Guilford Pharmaceuticals Expands Marketing and Distribution Agreement for GLIADEL(R) Wafer With Link Pharmaceuticals

  1049. [05/12/2004] Road Racing: Raising Hope to fight brain tumor

  1050. [05/10/2004] Loss Widens at Guilford Pharma

  1051. [05/06/2004] NEOPHARM ANNOUNCES NEW CLINICAL TRIAL DATA FOR IL13-PE38QQR IN BRAIN CANCER

  1052. [05/05/2004] Chemical brain scans may help diagnose recurrence

  1053. [05/04/2004] First-Line Chemotherapy With Cisplatin Plus Fractionated Temozolomide in Recurrent Glioblastoma Multiforme: A Phase II Study of the Gruppo Italiano Cooperativo di Neuro-Oncologia

  1054. [04/29/2004] BRAIN SURGERY WITHOUT A KNIFE: Stereotactic procedure is breakthrough for patients

  1055. [04/28/2004] Iressa news backgrounder: Testing of smart drug expands at M. D. Anderson Cancer Center

  1056. [04/27/2004] Gamma knife surgery for treatment of residual nonfunctioning pituitary adenomas after surgical debulking.

  1057. [04/23/2004] Ill teen has a high-tech helper

  1058. [04/21/2004] Temozolomide for treatment-resistant recurrent meningioma.

  1059. [04/15/2004] Effects of basic fibroblastic growth factor on the growth of human medulloblastoma xenografts.

  1060. [04/15/2004] Pilot study of estramustine added to radiosurgery and radiotherapy for treatment of high grade glioma.

  1061. [04/15/2004] Stereotactic radiosurgery for multiple brain metastases from breast carcinoma.

  1062. [04/15/2004] Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial.

  1063. [04/12/2004] A New York City First: Brain Cancer Patient Receives Unique Liquid Radiation Treatment at NewYork-Presbyterian/Weill Cornell

  1064. [04/07/2004] Management of cystic craniopharyngiomas with phosphorus-32 intracavitary irradiation.

  1065. [04/07/2004] Radiation-induced tumor after stereotactic radiosurgery and whole brain radiotherapy: case report and literature review.

  1066. [04/07/2004] Abbreviated Course of Radiation Therapy in Older Patients With Glioblastoma Multiforme: A Prospective Randomized Clinical Trial.

  1067. [04/07/2004] Molecular classification and survival prediction in human gliomas based on proteome analysis.

  1068. [04/07/2004] International Neuro-Oncology Update to be Held in Memphis

  1069. [04/03/2004] Cancer cluster inquiry begins

  1070. [04/02/2004] Guilford Presents Novel Research at the 95th Annual Meeting of The American Association for Cancer Research

  1071. [03/30/2004] Intraoperative subcortical stimulation mapping for hemispherical perirolandic gliomas located within or adjacent to the descending motor pathways: evaluation of morbidity and assessment of functional outcome in 294 patients.

  1072. [03/30/2004] Surgical removal of corpus callosum infiltrated by low-grade glioma: functional outcome and oncological considerations.

  1073. [03/30/2004] Primary chemotherapy for intracranial nongerminomatous germ cell tumors: results of the second international CNS germ cell study group protocol.

  1074. [03/29/2004] Resveratrol Suppresses the Angiogenesis and Tumor Growth of Gliomas in Rats.

  1075. [03/29/2004] Invisible light and special goggles may improve brain tumor surgery

  1076. [03/28/2004] Substitute mom: `He deserved a chance`

  1077. [03/26/2004] Cytoplasmic expression of nm23 predicts the potential for cerebral metastasis in patients with primary cutaneous melanoma

  1078. [03/26/2004] Cancer rates spur inquiry

  1079. [03/19/2004] Rebecca Libutti, 48, cancer`s tough foe

  1080. [03/17/2004] Researcher Developing Tumor Identification System for Surgery

  1081. [03/17/2004] Second-line treatment with carboplatin for recurrent or progressive oligodendroglial tumors after PCV (procarbazine, lomustine, and vincristine) chemotherapy: a phase II study.

  1082. [03/15/2004] Study Slams Some Alternative Cancer Treatments

  1083. [03/14/2004] Balloon helps doctor reach brain tumor

  1084. [03/12/2004] Gamma knife surgery for treatment of residual nonfunctioning pituitary adenomas after surgical debulking

  1085. [03/03/2004] Craniotomy for the resection of metastatic brain tumors in the U.S., 1988-2000: decreasing mortality and the effect of provider caseload.

  1086. [03/01/2004] For Brain Tumor Surgery in Children, High-Volume Hospitals Get Better Results

  1087. [02/28/2004] OpGen joins UW, Henry Ford Heath in Improving Brain Tumor Treatment

  1088. [02/23/2004] A functional polymorphism in the EGF gene is found with increased frequency in glioblastoma multiforme patients and is associated with more aggressive disease.

  1089. [02/21/2004] OpGen`s Collaboration With Henry Ford Hospital`s Hermelin Brain Tumor Center Will Enable Researchers To Determine Effectiveness of Drug Therapies For Patients

  1090. [02/17/2004] Brain Scans Used to Monitor Effect of Cancer Drug

  1091. [02/10/2004]

  1092. [02/10/2004] High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma.

  1093. [02/10/2004] Stereotactic radiosurgery as an alternative to fractionated radiotherapy for patients with recurrent or residual nonfunctioning pituitary adenomas.

  1094. [02/10/2004] Automaker`s robot arm finds use in cancer care

  1095. [02/07/2004] Thalidomide prolongs disease stabilization in those with recurrent glioblastoma.

  1096. [01/27/2004] Surgical Outcome following Resection of Contrast-Enhanced Pediatric Brainstem Gliomas.

  1097. [01/25/2004] Run/walk benefits Florida Brain Tumor Association

  1098. [01/19/2004] Recurrent primary fibrosarcoma of the brain treated with the GliaSite brachytherapy system: case report.

  1099. [01/13/2004] Neuropsychological outcome in children with optic pathway tumours when first-line treatment is chemotherapy.

  1100. [01/06/2004] Phase I study of topotecan in combination with concurrent radiotherapy in adults with glioblastoma.

  1101. [01/06/2004] Surgical resection and permanent brachytherapy for recurrent atypical and malignant meningioma.

  1102. [01/06/2004] Adenovirus/herpes simplex-thymidine kinase/ganciclovir complex: preliminary results of a phase I trial in patients with recurrent malignant gliomas.

  1103. [01/06/2004] Treatment of progressive or recurrent glioblastoma multiforme in adults with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration: a phase I/II multi-institutional trial.

  1104. [01/06/2004] Cytokine immuno-gene therapy for treatment of brain tumors.

  1105. [01/02/2004] Phase II Trial of Gefitinib in Recurrent Glioblastoma

  1106. [12/28/2003] 12 with brain tumors tied to Rohm & Haas - A study, to be released, is to provide clues to the mystery.

  1107. [12/27/2003] Woman hopes her story of tumor will help others

  1108. [12/24/2003] Rising malpractice insurance premiums frighten doctors

  1109. [12/24/2003] Stereotactic radiosurgery for brain metastases from gastrointestinal tract cancer.

  1110. [12/10/2003] Oligodendroglioma and anaplastic oligodendroglioma: clinical features, treatment, and prognosis.

  1111. [12/10/2003] Mutism after posterior fossa tumour resection in children: incomplete recovery on long-term follow-up.

  1112. [12/08/2003] Brain Cancer Advance

  1113. [12/02/2003] Phase II Trial of Gefitinib in Recurrent Glioblastoma.

  1114. [11/27/2003] Couple Thankful For Recovery

  1115. [11/26/2003] Adenovirus/Herpes Simplex-Thymidine Kinase/Ganciclovir Complex: Preliminary Results of a Phase I trial in Patients with Recurrent Malignant Gliomas

  1116. [11/25/2003] Neuropsychological outcome in children with optic pathway tumours when first-line treatment is chemotherapy

  1117. [11/24/2003] Renowned Surgeons Open Atlanta Brain and Spine Care

  1118. [11/20/2003] Trial Drugs Offer Hope for Brain Cancer

  1119. [11/19/2003] Patients` Bill Of Rights Saves Boy

  1120. [11/19/2003] Brain Cancer Research Moves Forward

  1121. [11/18/2003] Promising survival for patients with glioblastoma multiforme treated with individualised chemotherapy based on in vitro drug sensitivity testing.

  1122. [11/18/2003] Prognostic significance of annexin VII expression in glioblastomas multiforme in humans.

  1123. [11/17/2003] NeoPharm and Collaborators Present IL13-PE38QQR Clinical Data in Brain Cancer

  1124. [11/17/2003] Current status of malignant glioma chemotherapy - hype or hope?

  1125. [11/17/2003] The Hypoxia-Inducible Cell Death Gene BNIP3 In Malignant Gliomas

  1126. [11/14/2003] FOR THE LOVE OF COLYN: A Rockville Centre Lions Club Partnership Fundraising Event

  1127. [11/11/2003] Postoperative regression of desmoplastic infantile gangliogliomas: report of two cases.

  1128. [11/10/2003] Long-term Results after Radiosurgery for Benign Intracranial Tumors

  1129. [11/04/2003] To Operate - Or Not
    One family`s tough decision when good doctors differed


  1130. [10/26/2003] Local delivery of minocycline and systemic BCNU have synergistic activity in the treatment of intracranial glioma.

  1131. [10/26/2003] Cyclooxygenase-2 in oligodendroglial neoplasms.

  1132. [10/22/2003] Chilean party leader undergoing brain tumor treatment in Cuba

  1133. [10/10/2003] Jones and Bartlett Publishers Announces the Publication of 100 Questions & Answers About Brain Tumors

  1134. [10/08/2003] Gamma Knife Offers New Hope to People Suffering from Brain Tumors, Other Conditions

  1135. [10/03/2003] Benchmark study of brain tumors points to resection over biopsy as one key to survival

  1136. [09/29/2003] Radiotherapy alone or after subtotal resection for benign skull base meningiomas.

  1137. [09/27/2003] ALF has history of attacking labs
    Previous victims call animal-rights group terrorists


  1138. [09/25/2003] Antigen targeted in therapy for melanoma also prompts immune response in brain tumor cells

  1139. [09/18/2003] Radiosurgery Plays Critical Role in Battle Against Cancer

  1140. [09/17/2003] Relative survival rates and patterns of diagnosis analyzed by time period for individuals with primary malignant brain tumor, 1973-1997.

  1141. [09/17/2003] Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project.

  1142. [09/15/2003] Sick Kids researchers identify cancer stem cell for brain tumours

  1143. [09/09/2003] Immunogene therapy of recurrent glioblastoma multiforme with a liposomally encapsulated replication-incompetent Semliki forest virus vector carrying the human interleukin-12 gene--a phase I/II clinical protocol.

  1144. [09/09/2003] Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma.

  1145. [09/09/2003] Autologous adjuvant linked fibroblasts induce anti-glioma immunity: implications for development of a glioma vaccine.

  1146. [09/09/2003] Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression.

  1147. [09/09/2003] Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of recurrent glioblastoma: preliminary observations in a patient with a favorable response to therapy.

  1148. [09/09/2003] Study of the MIB-1 labeling index as a predictor of tumor progression in pilocytic astrocytomas in children and adolescents.

  1149. [09/09/2003] Gamma knife radiosurgery for pituitary adenoma: early results.

  1150. [09/03/2003] Role of early radiotherapy in the treatment of supratentorial WHO Grade II astrocytomas: long-term results of 97 patients.

  1151. [08/21/2003] New therapy, high spirits lift brain tumor patient

  1152. [08/21/2003] New brain cancer treatment extends survival for more patients
    Patients stay home, take a pill instead of IV chemotherapy


  1153. [08/09/2003] Study shows retinoids kill childhood brain tumor cells

  1154. [08/06/2003] Treatment helps patient beat rare cancer

  1155. [08/06/2003] Protein Can Predict Progression of Most Common Childhood Brain Tumor

  1156. [08/06/2003] Potentiation of radiation therapy by the oncolytic adenovirus dl1520 (ONYX-015)in human malignant glioma xenografts.

  1157. [07/27/2003] Racial differences in survival after diagnosis with primary malignant brain tumor.

  1158. [07/22/2003] Phase 1 study of temozolamide (TMZ) combined with procarbazine (PCB) in patients with gliomas.

  1159. [07/22/2003] Language functional magnetic resonance imaging in preoperative assessment of language areas: correlation with direct cortical stimulation.

  1160. [07/20/2003] Precision instrument: MIT-Beth Israel trial targets tumors

  1161. [07/15/2003] Wafers offer option for metastatic brain cancer treatment

  1162. [07/08/2003] Cancer research focuses on brain

  1163. [07/08/2003] High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas.

  1164. [07/08/2003] Neuropsychological effects of third ventricle tumor surgery.

  1165. [07/05/2003] B.C. woman responding to cutting-edge cancer vaccine

  1166. [07/01/2003] Phase II Study of First-Line Chemotherapy With Temozolomide in Recurrent Oligodendroglial Tumors: The European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971.

  1167. [07/01/2003] The natural history of incidental meningiomas.

  1168. [06/24/2003] Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project.

  1169. [06/24/2003] Wafer attacks tumors

  1170. [06/20/2003] A risky operation offers family hope

  1171. [06/16/2003] Phase II Evaluation of Temozolomide and 13-cis-Retinoic Acid for the Treatment of Recurrent and Progressive Malignant Glioma: A North American Brain Tumor Consortium Study.

  1172. [06/16/2003] Phase II Trial of Thalidomide and Carmustine for Patients With Recurrent High-Grade Gliomas.

  1173. [06/14/2003] Up-front chemotherapy temozolomide in the treatment of Gliomatosis Cerebri: Analysis of 33 patients

  1174. [06/14/2003] Loco-regional radioimmunotherapy of malignant glioma by means of a humanised antibody hR3 (raised against epidermal growth factor receptors) labelled with Y-90

  1175. [06/14/2003] Phase I-II study of ZD-1839 for recurrent malignant gliomas and meningiomas progressing after radiation therapy

  1176. [06/14/2003] Comparison of survival of patients in the phase I study of motexafin gadolinium (MGd) with radiation therapy (RT) for glioblastoma multiforme (GBM), with a matched cohort of patients from the RTOG RPA glioma database

  1177. [06/14/2003] Safety and efficacy of temozolomide concomitant and sequential to radiotherapy in glioblastoma multiforme: Results of a phase II multicentric study

  1178. [06/14/2003] Intracavitary placement of lymphokine-activated killer (LAK) cells after resection of recurrent glioblastoma

  1179. [06/14/2003] Temozolomide in glioblastoma: 4 years` experience with monthly or fortnigthly schedule

  1180. [06/10/2003] Locoregional radioimmunotherapy in selected patients with malignant glioma: experiences, side effects and survival times.

  1181. [06/10/2003] Cerebral glucose metabolism in long-term survivors of childhood primary brain tumors treated with surgery and radiotherapy.

  1182. [06/08/2003] Altered cold virus kills brain tumors in mice

  1183. [06/07/2003] A neurosurgeon `crisis`: Insurer drops doctors` group

  1184. [06/07/2003] Tarceva (erlotinib HCI) Shows Encouraging Safety Profile and Activity in Phase I Clinical Study in Patients with Malignant Glioma

  1185. [06/04/2003] The effects of hydrogen peroxide on brain and brain tumors.

  1186. [06/04/2003] Principles of treatment of the pineal region tumors.

  1187. [06/02/2003] Rare radiation therapy available at Nashville hospital

  1188. [05/31/2003] Man on His Way to Beat Cancer

  1189. [05/27/2003] Neuropsychological functioning after surgery in children treated for brain tumor.

  1190. [05/27/2003] Brain metastases treated with radiosurgery alone: an alternative to whole brain radiotherapy?

  1191. [05/27/2003] Correlation between genetic alteration and long-term clinical outcome of patients with oligodendroglial tumors, with identification of a consistent region of deletion on chromosome arm 1p.

  1192. [05/25/2003] Brain tumor patients (who have not had surgery or radiation yet) needed for art study..

  1193. [05/22/2003] Boron neutron capture therapy for glioblastoma multiforme: clinical studies in Sweden.

  1194. [05/22/2003] Boron neutron capture therapy of brain tumors: clinical trials at the finnish facility using boronophenylalanine.

  1195. [05/22/2003] Methionine positron emission tomography of recurrent metastatic brain tumor and radiation necrosis after stereotactic radiosurgery: is a differential diagnosis possible?

  1196. [05/22/2003] Treatment of low-grade diffuse astrocytomas by surgery and human fibroblast interferon without radiation therapy.

  1197. [05/21/2003] Gamma knife radiosurgery provides long-term control of benign brain tumors, says Pitt study

  1198. [05/19/2003] Gap funds could propel discovery for brain tumors

  1199. [05/14/2003] Intraoperative Magnetic Resonance Imaging: Impact on Brain Tumor Surgery

  1200. [05/12/2003] Impact of chromosome 1p status in response of oligodendroglioma to temozolomide: preliminary results.

  1201. [05/12/2003] Prosecutors Drop Fight to Force Surgery for 2-Year-Old Michigan Girl

  1202. [05/07/2003] CALGARY, Alberta, May 7, 2003 -- Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) (‘Oncolytics’) today announced that enrollment has resumed in the Phase I component of its clinical study examining the use of REOLYSIN® in the treatment of recurrent malignant glioma, the most aggressive form of brain cancer.

  1203. [05/07/2003] Parents’ rights at issue

  1204. [05/07/2003] Altered Cold Virus Kills Tumors in Mice Genetically Altered Cold Virus Can Kill Brain Tumors and Spare Healthy Tissue, Researchers Say

  1205. [05/06/2003] New Approaches for the Treatment of Refractory Meningiomas

  1206. [05/01/2003] Easing a hospital stay Scout collects DVDs to entertain fellow cancer sufferers

  1207. [04/30/2003] Moffitt Center Neuro-Oncology Study of Wafer Implanted During Surgery Shows Zero Tumor Recurrence

  1208. [04/30/2003] NeoPharm Announces New Clinical Trial Data for IL13-PE38QQR in Brain Cancer

  1209. [04/29/2003] Two studies evaluating irinotecan treatment for recurrent malignant glioma using an every-3-week regimen.

  1210. [04/29/2003] The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.

  1211. [04/18/2003] Treatment Of Child`s Brain Tumor Debated

  1212. [04/18/2003] Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients.

  1213. [04/18/2003] A longitudinal neuropsychological study of partial brain radiation in adults with brain tumors.

  1214. [04/18/2003] Surgical treatment of pituitary tumors in the elderly: clinical outcome and long-term follow-up.

  1215. [04/18/2003] New approach to tumor therapy for inoperable areas of the brain: chronic intraparenchymal drug delivery.

  1216. [04/09/2003] A longitudinal neuropsychological study of partial brain radiation in adults with brain tumors

  1217. [04/09/2003] Gamma linolenic acid therapy of human gliomas

  1218. [04/08/2003] Combined surgery, radiation, and PCV chemotherapy for astrocytomas compared to oligodendrogliomas and oligoastrocytomas WHO grade III.

  1219. [04/02/2003] Therapy of Glioblastoma Multiforme Improved by the Antimutagenic Chloroquine

  1220. [04/01/2003] Delayed repletion of O6-methylguanine-DNA methyltransferase resulting in failure to protect the human glioblastoma cell line SF767 from temozolomide-induced cytotoxicity.

  1221. [04/01/2003] Salvage chemotherapy with CPT-11 for recurrent oligodendrogliomas.

  1222. [03/31/2003] Vicenza Hospital in Italy Opens First CyberKnife(R) Radiosurgery Center In Europe

  1223. [03/31/2003] Long-Term Neurological Outcome of Childhood Brain Tumors Treated by Surgery Only

  1224. [03/24/2003] SURGEONS DID A ‘BAIT & SWITCH`: TUMOR TEEN

  1225. [03/24/2003] Focusing brain surgery with robots

  1226. [03/24/2003] The impact of provider volume on mortality after intracranial tumor resection.

  1227. [03/19/2003] Phase II study of chemotherapy with ACNU plus cisplatin followed by cranial irradiation in patients with newly diagnosed glioblastoma multiforme.

  1228. [03/19/2003] Meningioma-associated brain oedema: the role of angiogenic factors and pial blood supply.

  1229. [03/18/2003] Pediatric Supratentorial High-Grade Gliomas

  1230. [03/15/2003] Treatment Benefits Elderly Brain Cancer Patients

  1231. [03/15/2003] Treatment depends on type of growth, patient`s health

  1232. [03/12/2003] Treatment of Low-grade Diffuse Astrocytomas by Surgery and Human Fibroblast Interferon without Radiation Therapy

  1233. [03/12/2003] Impact of Chromosome 1p Status in Response of Oligodendroglioma to Temozolomide: Preliminary Results

  1234. [03/12/2003] Endonasal transsphenoidal approach for pituitary adenomas and other sellar lesions: an assessment of efficacy, safety, and patient impressions.

  1235. [03/12/2003] Radiosurgery in patients with renal cell carcinoma metastasis to the brain: long-term outcomes and prognostic factors influencing survival and local tumor control.

  1236. [03/01/2003] Introgen Preclinical Studies Show Non-Viral Delivery System Effectively Targets Tumors

  1237. [02/26/2003] FDA Approves Expanded Use Of Gliadel Wafer (Polifeprosan 20 With Carmustine Implant) For Primary Malignant Brain Cancer

  1238. [02/25/2003] Peregrine Pharmaceuticals Receives FDA Approval for its Cotara(TM) Phase III Registration Trial Design for Brain Cancer

  1239. [02/25/2003] Gamma knife radiosurgery for the treatment of cavernous sinus meningiomas.

  1240. [02/25/2003] Properly selected patients with multiple brain metastases may benefit from aggressive treatment of their intracranial disease.

  1241. [02/25/2003] High-dose-rate stereotactic brachytherapy for patients with newly diagnosed glioblastoma multiformes.

  1242. [02/18/2003] Phase II Trial of Temozolomide in Patients With Progressive Low-Grade Glioma.

  1243. [02/04/2003] A prospective study on glioblastoma in the elderly.

  1244. [02/04/2003] Determination of histopathological tumor grade in neuroepithelial brain tumors by using spectral pattern analysis of in vivo spectroscopic data.

  1245. [01/21/2003] Endocrine and cardiovascular late effects among adult survivors of childhood brain tumors: Childhood Cancer Survivor Study

  1246. [01/21/2003] A prospective study on glioblastoma in the elderly

  1247. [01/21/2003] A planned combined stereotactic approach for cystic intracranial tumors. Report of two cases.

  1248. [01/21/2003] Radiosurgery for residual or recurrent nonfunctioning pituitary adenoma.

  1249. [01/16/2003] Singapore develops robot to help in surgery

  1250. [01/07/2003] Intratumoral bleeding in meningioma after gamma knife radiosurgery.

  1251. [01/07/2003] Tumor-Tracking Missiles: Researchers Develop a Possible New Treatment Strategy for Deadly Brain Tumors

  1252. [01/04/2003] Survival and pattern of failure in brain metastasis treated with stereotactic gamma knife radiosurgery.

  1253. [01/04/2003] Radiosurgery for non-small cell lung carcinoma metastatic to the brain: long-term outcomes and prognostic factors influencing patient survival time and local tumor control.

  1254. [01/01/2003] Brain tumor patients helped

  1255. [12/28/2002] Induction of Glioblastoma Apoptosis Using Neural Stem Cell-mediated Delivery of Tumor Necrosis Factor-related Apoptosis-inducing Ligand1

  1256. [12/23/2002] Intracranial navigation by using low-field intraoperative magnetic resonance imaging: preliminary experience.

  1257. [12/23/2002] Oncolytics Biotech Inc. today announced positive interim safety results from the Phase I component of its clinical study examining the use of REOLYSIN® in the treatment of recurrent malignant glioma, the most aggressive form of brain cancer.

  1258. [12/21/2002] New York Brain Tumor Project Launched at New York Weill Cornell Medical Center

  1259. [12/19/2002] Cancer patient sues HMO to cover chemotherapy drug

  1260. [12/19/2002] Unlikely Treatment May Help Brain Cancer Patients
    Synthetic Scorpion Venom Injected Into Patient`s Brain


  1261. [12/19/2002] Precise cancer weapon on way. Lance Armstrong in Charlotte to promote new linear accelerator

  1262. [12/18/2002] Wistar Institute-Developed Antibody Shows Promise Against Brain Tumors in Drexel University Trial

  1263. [12/18/2002] Polymer delivery of camptothecin against 9L gliosarcoma: release, distribution, and efficacy.

  1264. [12/09/2002] Prognostic factors in patients who survived more than 10 years after undergoing surgery for metastatic brain tumors. Report of 5 cases and review of the literature.

  1265. [12/09/2002] Organization of language areas in bilingual patients: a cortical stimulation study.

  1266. [12/06/2002] Cerebrovascular mortality in patients with pituitary adenoma

  1267. [12/02/2002] Queen’s leading with brain treatment

  1268. [11/25/2002] Methodist Foresees Fruits of Lab Seeding research to aid patients

  1269. [11/12/2002] Local chemotherapy with cisplatin-depot for glioblastoma multiforme.

  1270. [11/12/2002] Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma.

  1271. [11/08/2002] Repeated gamma knife surgery for multiple brain metastases from renal cell carcinoma.

  1272. [11/07/2002] Published Data on IL13-PE38 Identifies Mechanism of Drug Action for The Treatment of Malignant Glioma

  1273. [11/01/2002] GUILFORD SUBMITS TO FDA AN AMENDMENT TO GLIADEL® WAFER SUPPLEMENTAL NEW DRUG APPLICATION

  1274. [10/23/2002] Results of stereotactic radiosurgery in patients with hormone-producing pituitary adenomas: factors associated with endocrine normalization.

  1275. [10/23/2002] Long-term outcome after resection of benign cerebellar astrocytomas in children and young adults (0-19 years): report of 110 consecutive cases.

  1276. [10/23/2002] Prognostic factors in children and adolescents with low-grade oligodendrogliomas.

  1277. [10/22/2002] Oates` cancer has not returned

  1278. [10/18/2002] Gift to be used to buy CyberKnife for Bristol hospital

  1279. [10/18/2002] Gift to be used to buy CyberKnife for Bristol hospital

  1280. [10/17/2002] a Tribute to Excellence

  1281. [10/17/2002] Elusive Brain Tumor Cells Tracked In Mice With Modified Neural Stem Cells

  1282. [10/17/2002] Direct Therapeutics Receives Approval to Begin European Trial Of New Brain Cancer Drug - Trial Will Evaluate DTI-015 in Patients With Newly Diagnosed High-Grade Glioma, the Most Aggressive and Deadly Form of Brain Cancer

  1283. [10/16/2002] Synthesized Scorpion Venom Basis for New Brain Cancer Drug Clinical Trials to Begin Editor`s note (10/16/2002) - trial is now open!

  1284. [10/16/2002] Intraoperative MRI and Adjuvant Radiosurgery

  1285. [10/15/2002] Brain operations guided by real-time two-dimensional ultrasound: new possibilities as a result of improved image quality.

  1286. [09/27/2002] New Hope for Patients With Brain Tumors

  1287. [09/25/2002] High-Dose Measles Vaccine Could Fight Brain Tumors

  1288. [09/24/2002] Fractionated Stereotactic Radiotherapy for the Treatment of Optic Nerve Sheath Meningiomas: Preliminary Observations of 33 Optic Nerves in 30 Patients with Historical Comparison to Observation with or without Prior Surgery.

  1289. [09/19/2002] GUILFORD ANNOUNCES GLIADEL® WAFER PHASE III LONG-TERM SURVIVAL RESULTS IN PRIMARY BRAIN CANCER

  1290. [09/16/2002] The Apurinic/Apyrimidinic Endonuclease Activity of Ape1/Ref-1 Contributes to Human Glioma Cell Resistance to Alkylating Agents and Is Elevated by Oxidative Stress1

  1291. [09/16/2002]

  1292. [09/09/2002] NeoPharm Announces Additional Clinical Data for IL13-PE38 at European Association of Neuro-Oncology (EANO) Congress Encouraging Preliminary Data From Ongoing Phase I/II Trial Presented On Potential New Treatment for Deadly Brain Cancer

  1293. [08/25/2002] New drug may hold answer to cancer

  1294. [08/18/2002] Cancer patient takes chance on new Calgary treatment

  1295. [08/15/2002] Stereotactic radiosurgery providing long-term tumor control of cavernous sinus meningiomas.

  1296. [08/15/2002] Craniopharyngioma in adults and children: a study of 122 surgical cases.

  1297. [08/15/2002] Late cognitive and radiographic changes related to radiotherapy: initial prospective findings.

  1298. [08/15/2002] Synergistic effect of genistein and BCNU on growth inhibition and cytotoxicity of glioblastoma cells. Editor`s note: this article shows that genistein - which is a health food supplement - found in soy beans, may improve the results of BCNU chemotherapy.. at least in the test tube!

  1299. [08/15/2002] Gemcitabine and radiotherapy in the treatment of brain metastases from transitional cell carcinoma of the bladder: a case report. <

  1300. [08/15/2002] Intrathecal methotrexate affects cognitive function in children with medulloblastoma.

  1301. [08/15/2002] Gene expression microarray analysis reveals YKL-40 to be a potential serum marker for malignant character in human glioma. Editor`s note: this is an experimental new blood test for glioblastomas!

  1302. [08/15/2002] Leading Physicians in the Treatment of Brain Tumors to Speak at Local Symposium

  1303. [08/06/2002] Dad loses job -- and insurance Father blames firing on his son`s illness

  1304. [08/05/2002] Using Sound Waves to Deliver Drugs to the Brain

  1305. [07/22/2002] Glioblastoma Distance Healing Project NOW RECRUITING PATIENTS WITH GLIOBLASTOMA

  1306. [07/16/2002] Pratt & Whitney leaves behind a trail of cancer.

  1307. [07/07/2002] Operations led to tragedies for two patients By Carla McClain

  1308. [07/03/2002] Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) (‘Oncolytics’) has started a Phase I/II brain cancer clinical trial with REOLYSIN®.

  1309. [05/30/2002] Jeffery Williams, Hopkins’ Neurosurgeon, Dies at 50

  1310. [05/26/2002] Phase II trial of BCNU, temozolamide (TMZ) plus intraarterial cisplatin (CDDP) in unresectable or recurrent high grade glioma Preliminary data suggest that this chemotherapy combination is active and well tolerated.

  1311. [05/26/2002] The role of 3-step radioimmunotherapy (RIT) as adjuvant treatment in malignant gliomas Three-step radioimmunotherapy promises to have an important role as adjuvant treatment in high grade gliomas, particularly in glioblastoma where it impedes progression, prolonging time to relapse and overall survival.

  1312. [05/26/2002] First line chemotherapy with cisplatin plus fractionated temozolomide (bid) in recurrent glioblastoma (GBM). This new regimen of DDP plus bid TMZ is effective in chemonaive recurrent GBM, with acceptable toxicity

  1313. [05/26/2002] Phase II study of temozolomide (TMZ) without radiotherapy in newly diagnosed glioblastoma multiforme (GBM) in an elderly population TMZ without radiotherapy may offer a safe, convenient, and efficient therapeutic alternative in elderly patients with newly diagnosed GBM.

  1314. [05/26/2002] Role of temozolomide (TMZ) for brain relapsed tumors: preliminary results Use of temodar as sole chemotherapy agent showed positive results in pts who had already had surgery, radiotherapy and chemotherapy and had recurrence of tumor.

  1315. [05/26/2002] Concurrent chemoradiotherapy in chemo- naive operated glioblastoma multiforme: a phase II study Pts given Docetaxel on first treatment day of each radiotherapy (RT) week with survival rate comparable to treatment plan of chemotherapy after RT.

  1316. [05/26/2002] Randomized phase II study of temozolomide (TMZ) with and without the matrix metalloprotease (MMP) inhibitor prinomastat in patients (pts) with glioblastoma multiforme (GBM) following best surgery and radiation therapy No significant difference between survival rate of pt treated with temodar + prinomastat vs temodar + placebo.

  1317. [05/26/2002] Neoadjuvant chemotherapy with fluvastatin, carboplatin and vincristine for the treatment of low grade astrocytomas (LGA): a phase II study Pediatric study of low grade astrocytomas showed good response with the addition of fluvastatin to chemotherapy regimen of carboplatin and vincristine; due to small sample size, more studies needed.

  1318. [05/26/2002] Safety profile and activity of high-dose temozolomide given daily x 3 every 2 weeks in patients with primary brain tumors. Temador was given safely at escalated dosages on days 1-3 and 14-16 every 28 days.

  1319. [05/01/2002] Impaired Body Clock Speeds Tumor Growth in Mice (Reuters)
    The destruction of the body`s natural rhythms accelerated the growth of cancerous tumors in laboratory animals, according to the results of a study.
    - Apr 30 11:38 PM ET


  1320. [04/29/2002] Gertz plays `Gilda` with a fond giggle (USA TODAY)
    ... possibility of losing a spouse after her husband, financier Tony Ressler, was diagnosed with a brain tumor in 1995 and underwent surgery....
    - Apr 29 6:10 AM ET


  1321. [04/26/2002] Pets Treated At High-Tech Hospital (KPRC Click2Houston.com)
    ...The facility treats tumors with chemotherapy or radiation treatments, using equipment similar to what`s used at M.D. Anderson......-- everything from removing a brain tumor to orthoscopic knee surgery, according to News2Houston. Hilde`s owner doesn`t know how...
    - Apr 25 7:21 PM ET


  1322. [04/23/2002] Treating Fibroids a New Way (HealthSCOUT)
    ... nutrition and spiritual techniques to shrink the noncancerous tumors and circumvent the need for invasive procedures. "A great many women come to me already...... meat and dairy products to violence on television, which can affect the limbic system of the brain and change levels of the hormone in your body. Deficient levels of vitamin B6 can also rob...
    - Apr 22 11:56 PM ET


  1323. [04/11/2002] Brain Tumors Safely Removed on Outpatient Basis (Reuters)
    Brain tumors can be removed safely and effectively without an overnight stay in the hospital, Canadian researchers reported here this week.
    - Apr 10 1:41 PM ET


  1324. [04/06/2002] Fund-Raiser Will Help Child`s Medical Bills (KPRC Click2Houston.com)
    Shelby Yarbrough, 9, is fighting for her life. Last year, Shelby was diagnosed with Anaplastic Apendymoma, a brain tumor.
    - Apr 05 4:22 PM ET


  1325. [04/04/2002] Padres Acquire Left-Handed Reliever (AP)
    ...Ramsay underwent surgery Jan. 23 to remove a brain tumor....
    - Apr 03 8:18 PM ET


  1326. [04/03/2002] Painting What`s Left of Faces, Sometimes What`s Behind (The New York Times)
    ... people with severe facial deformities: accident victims, cancer sufferers with disfiguring head tumors and people with congenital defects in their faces, mouths and jaws....... the subjects included Henry Ekpe, 35, a nurse with a malignant bone tumor whose face was reconstructed after the removal of his right eye,......I`ve removed his lower jaw, his upper jaw, his eye socket, his forehead, part of his brain....
    - Apr 03 8:53 AM ET


  1327. [04/02/2002] Orioles 10, Yankees 3 (AP)
    ... pregame ceremony was reserved for former Orioles manager Johnny Oates, undergoing treatment for brain tumor....
    - Apr 01 6:44 PM ET


  1328. [04/02/2002] Al: Orioles Beat Yankees, 10-3 (Reuters)
    ... the former Orioles manager who recently underwent surgery to remove a brain tumor....
    - Apr 01 7:54 PM ET


  1329. [04/02/2002] AL: Orioles Beat Yankees, 10-3 (Reuters)
    ... the former Orioles manager who recently underwent surgery to remove a brain tumor....
    - Apr 01 7:54 PM ET


  1330. [04/02/2002] Al Wrap: Batista`s Homer Leads Orioles Vs. Yankees (Reuters)
    ... Johnny Oates throwing out the first pitch after having recently undergone surgery to remove a brain tumor, the sellout Camden Yards crowd of 48,058 was looking for something special on opening...
    - Apr 02 2:13 AM ET


  1331. [04/02/2002] Aces in a Hole on Opening Day (AP)
    ... Yards was reserved for Johnny Oates, the former Orioles manager undergoing treatment for a brain tumor....
    - Apr 02 5:33 AM ET


  1332. [04/02/2002] Martinez, Clemens Rocked in Openers (AP)
    ... Yards was reserved for Johnny Oates, the former Orioles manager undergoing treatment for a brain tumor....
    - Apr 02 6:29 AM ET


  1333. [03/22/2002] Doctor: Cell Phones May Cause Cancer (KGTV TheSanDiegoChannel.com)
    ...~~~Medical science now shows us that cell phone users are at an increased risk of tumors -......-- an increased risk of cancer; brain cancer and eye cancer, that we know of so far,~~~ Carlo said. Gibb Brower has undergone surgery......Gibb Brower has undergone surgery three times over the last two years to remove a fatal brain tumor, which he said came from talking on a cell phone 1,200 minutes a month. ~~~This is pretty much...
    - Mar 21 7:05 PM ET


  1334. [03/22/2002] March 22 in Entertainment History (AP)
    ...In 1994, singer-bassist-producer Dan Hartman died of a brain tumor in Westport, Connecticut....
    - Mar 22 8:52 AM ET


  1335. [03/22/2002] Chemo Slightly Extends Brain Cancer Survival (Reuters)
    Adding chemotherapy to the treatment of some patients with aggressive brain tumors may make a modest difference in their survival, UK researchers report.
    - Mar 22 11:00 AM ET


  1336. [03/21/2002] Guilford gets non-approvable letter for Gliadel (Reuters Securities)
    Guilford Pharmaceuticals Inc. said on Wednesday that it has received a non-approvable letter from U.S. regulators for its Gliadel wafer to treat patients with newly diagnosed brain cancer.
    - Mar 20 10:02 AM ET


  1337. [03/21/2002] FDA rejects Guilford`s Gliadel application (Reuters Securities)
    Guilford Pharmaceuticals Inc. said on Wednesday U.S. regulators rejected its bid to expand use of its Gliadel brain cancer therapy to newly diagnosed patients, sending the stock down nearly 20 percent.
    - Mar 20 1:33 PM ET


  1338. [03/21/2002] FDA rejects Guilford cancer bid, shares reel (Reuters Securities)
    Guilford Pharmaceuticals Inc. said on Wednesday U.S. regulators rejected its bid to expand use of a key drug treatment for brain cancer patients, sending its shares down 20 percent to a 6-1/2 year low.
    - Mar 20 2:59 PM ET


  1339. [03/21/2002] Guilford Shares Fall After FDA Decision (Reuters)
    Guilford Pharmaceuticals Inc. said on Wednesday U.S. regulators rejected its bid to expand use of a key drug treatment for brain cancer patients, sending its shares down 20 percent to a 6-1/2 year low.
    - Mar 20 3:19 PM ET


  1340. [03/20/2002] Tongue Cancer Still Rare, but Rates Are Increasing (Reuters)
    ... a cause of head and neck cancer, since DNA of the virus has been detected in head and neck tumors.......This category does not include brain cancer....
    - Mar 19 1:50 PM ET


  1341. [03/13/2002] New Technology That Could Save Your Life (SPACE.com)
    ...It would assess physical traumas to the brain and could also monitor for psychosocial disorders that can develop in the confining environment......Early on, tumors develop only in that area, yet chemotherapy radiates the entire body.......Compared to mammograms that find telltale calciferous deposits that are formed later in tumor development, the new system finds breast cancer at an earlier,...
    - Mar 13 8:16 AM ET


  1342. [03/01/2002] Medtronic Neurosurgery Receives FDA Clearance for New Medical Device to Treat Hydrocephalus (Business Wire)
    Medtronic Neurosurgery, part of Medtronic, Inc., received FDA clearance this month to begin U.S. sales of the Strata(TM) valve, a new medical device used in the treatment of hydrocephalus, an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain.
    - Feb 28 4:49 PM ET


  1343. [02/23/2002] Ebert Under the Knife (E! Online)
    ...~~~I am having surgery to remove a malignant tumor on my thyroid gland....... a reviewer for the rival Chicago Tribune, never fully recovered after having a brain tumor removed and died at the age of 53. ...
    - Feb 22 7:55 PM ET


  1344. [02/23/2002] Virus Might Be Linked to Childhood Brain Cancer (HealthSCOUT)
    FRIDAY, Feb. 22 (HealthScoutNews) -- Researchers have detected a protein produced by a common virus in human brain tumors, raising the possibility that the virus plays a role in the development of the most common malignant brain cancer in children.
    - Feb 22 11:54 PM ET


  1345. [02/22/2002] Robert Ebert to Have Growth Removed (AP)
    ...~~~I am having surgery to remove a malignant tumor in my thyroid gland,~~~ Ebert said in a statement.......Siskel died of complications from brain surgery at age 53 in 1999....
    - Feb 21 1:52 PM ET


  1346. [02/22/2002] Roger Ebert to Have Growth Removed (AP)
    ...~~~I am having surgery to remove a malignant tumor in my thyroid gland,~~~ Ebert said in a statement.......Siskel died of complications from brain surgery at age 53 in 1999....
    - Feb 21 4:22 PM ET


  1347. [02/22/2002] Ebert Under the Knife (E! Online)
    ...~~~I am having surgery to remove a malignant tumor on my thyroid gland....... a reviewer for the rival Chicago Tribune, never fully recovered after having a brain tumor removed and died at the age of 53. ...
    - Feb 21 7:35 PM ET


  1348. [02/22/2002] EBERT CANCER SURGERY (PageSix.com)
    ... years to the day that his former on-air partner, Gene Siskel, died from complications of a brain tumor....
    - Feb 22 3:42 AM ET


  1349. [02/21/2002] Podiatrist, ex-employee settle harassment lawsuit (Akron Beacon Journal)
    ...Their working relationship ended in 1997, shortly after Gordon had brain surgery to remove a tumor....
    - Feb 21 6:53 AM ET


  1350. [02/10/2002] Obituaries in the News (AP)
    ...~~~ died Feb. 1 of complications from a brain tumor and stroke....
    - Feb 09 7:41 PM ET


  1351. [02/04/2002] Health Highlights: Feb. 3, 2002 (HealthSCOUT)
    ...The vaccine appears to prevent the build-up of plaque in the brain that is characteristic of Alzheimer`s disease. Studies in rats showed that Alzheimer`s was...... prostate cancer is "clinically useless" at determining the size or severity of a man`s tumor, and is only of "limited" value at predicting cure rates from surgery to remove the...
    - Feb 03 6:09 AM ET


  1352. [02/03/2002] Health Highlights: Feb. 2, 2002 (HealthSCOUT)
    ...The vaccine appears to prevent the build-up of plaque in the brain that is characteristic of Alzheimer`s disease. Studies in rats showed that Alzheimer`s was...... prostate cancer is "clinically useless" at determining the size or severity of a man`s tumor, and is only of "limited" value at predicting cure rates from surgery to remove the...
    - Feb 02 5:53 AM ET


  1353. [02/01/2002] Weymouth Boy Gets Superbowl Gift (WCVB TheBostonChannel.com)
    ...Gary Lowell had a brain tumor removed last fall....
    - Jan 31 7:55 AM ET


  1354. [01/28/2002] Worlds come together in Copley (Akron Beacon Journal)
    ... the project after having what she describes as a religious experience while recovering from brain tumor surgery in 1996. Full story at Akron Beacon Journal ...
    - Jan 28 7:37 AM ET


  1355. [01/25/2002] Charity Auction For Death Frontman Turns Ugly (SonicNet)
    ... had to undergo expensive medical treatment and surgery on a malignant brain tumor he had been battling for more than two years....
    - Jan 24 7:37 PM ET


  1356. [01/23/2002] Blake`s Senior Continues Recovery After Coma (WCCO Channel4000.com)
    ... in goal for Blake during a Jan. 4, 2001, game, the team`s co-captain was diagnosed with a brain tumor....
    - Jan 22 7:22 PM ET


  1357. [01/22/2002] Padres` Ramsay to Have Tumor Removed (AP)
    San Diego Padres relief pitcher Rob Ramsay is scheduled to have surgery Wednesday to remove a brain tumor.
    - Jan 21 8:04 PM ET


  1358. [01/19/2002] Cakewalk: Thank You, and Good Night (L.A. Weekly)
    But there was more. Over the months and then years, my sister, through her secretary, Juliana, reported complications and subsequent poor recoveries in hospitals where the nephew was alone and too often unattended. Steroid treatments were blowing him up, and he had gone completely blind. This past year, Vincent had grown another tumor, this time on the brain stem, and a local cadre of surgeons had decided not to operate. Keith Black had decided the same thing. Vincent sang to himself to keep up his spirits. He wanted to go to school, but the isolation of the reservation and a lack of money made things difficult. Juliana visited him faithfully, bringing homemade tamales or zucchini bread or other things her sister Hope, the boy’s mother, might be able to sell on the reservation. She brought extra money if she had it. My sister and I went from feeling deeply, helplessly sorry to being outraged about the whole thing. The wild injustice of the tumor became, by tacit agreement, our story. Our initial mist of mutual concern about a likely newspaper clipping quickly condensed into a name — Vincent Hinman — and a presence that assumed a regular place in our daily exchanges about the world and the people we knew. We both became soundly vested in the terrifying fortunes of someone we had never met.
    - Jan 18 2:00 PM ET


  1359. [01/16/2002] Ex-Olympic Skater Seybold-Catron To Have Tumor Removed (WRTV TheIndyChannel.com)
    Former Olympic figure skater Kim Seybold-Catron, who carried the Olympic flame in Indianapolis during a relay last week, will undergo surgery in March to remove a non-malignant brain tumor.
    - Jan 15 10:21 PM ET


  1360. [01/16/2002] Ex-Olympic Skater Fighting Brain Tumor (AP)
    Former Olympic figure skater Kim Seybold-Catron is battling a recurrence of a brain tumor that surgeons removed in 1995.
    - Jan 16 6:51 AM ET


  1361. [01/06/2002] A Pragmatic Modernist Prepares for Post-Modern Life (The New York Times)
    ... you look at it through Bill`s eyes, his feeling was that the crucial ingredients were eye, brain power, toughness.......Then, last summer, a routine exam picked up new tumors on his lung, and Mr....
    - Jan 06 9:09 AM ET


  1362. [01/03/2002] 2001 Necrology: Playbill On-Line Recalls Theatre Folk Who Passed On (Playbill)
    ... orchestrator and dance arranger for such musicals as Fiorello! and Tenderloin - Aug. 18 of a brain tumor....
    - Jan 02 4:02 PM ET


  1363. [12/29/2001] Foundation grants teen`s wish for a piano (Kansas City Star)
    ...Doctors diagnosed his brain tumor almost 12 months ago....
    - Dec 29 7:03 AM ET


  1364. [12/19/2001] Drug May Give Brain Cancer Patients More Time (Cleveland - NewsNet5)
    Doctors have a new weapon in their fight to help treat the nearly 18,000 Americans who are diagnosed each year with a brain tumor.
    - Dec 18 5:57 PM ET


  1365. [12/11/2001] Today`s Health Highlights: Dec. 10, 2001 (HealthSCOUT)
    ...Ahmed and Mohammed Ibrahim Mohammed, are 6 months old and share a small part of their brain, said Dr. Nasser Abdel Al, head of the neonatal surgical intensive care unit at Cairo Hospital,......But doubt has been cast upon the promises that early detection of breast cancer tumors would reduce death rates by 30 percent....
    - Dec 10 12:08 PM ET


  1366. [12/08/2001] "ER" Loses Another Doc (E! Online)
    ...Greene, who underwent surgery for a brain tumor, will probably pass away in a big sweeps finale in May,...
    - Dec 07 8:41 PM ET


  1367. [12/07/2001] Guilford gets partial support for new Gliadel use (Reuters Securities)
    Guilford Pharmaceuticals Inc.(NasdaqNM: GLFD - news ) received partial support on Thursday from a U.S. advisory panel for the company`s push to expand approved uses for its Gliadel Wafer to treat certain brain tumors.
    - Dec 06 7:09 PM ET


  1368. [12/07/2001] Guilford Gets Partial Support for New Gliadel Use (Reuters)
    Guilford Pharmaceuticals Inc. received partial support on Thursday from a U.S. advisory panel for the company`s push to expand approved uses for its Gliadel Wafer to treat certain brain tumors.
    - Dec 06 7:12 PM ET


  1369. [12/04/2001] High School Student Attaining One Of Her Goals (WYFF TheCarolinaChannel.com)
    ...But she was forced to run an unfamiliar race with life when she had surgery to remove a brain tumor....
    - Dec 03 5:05 PM ET


  1370. [12/04/2001] Older Age Dampens Response to Radiation Therapy (Reuters)
    Old age may limit the response to radiation therapy in patients with a certain type of brain cancer, suggesting that additional therapies should be investigated for older patients, according to researchers.
    - Dec 03 6:10 PM ET


  1371. [12/02/2001] Caring friends` recipe for survival (Contra Costa Times)
    ... physical education teacher who`d never had more than a cold her entire life, was diagnosed with a brain tumor....
    - Dec 02 9:21 AM ET


  1372. [12/01/2001] Ex-Beatle George Harrison dies aged 58 (Reuters)
    ... also had surgery for lung cancer in 2001 and was reportedly treated at a Swiss clinic for a brain tumor....
    - Nov 30 3:57 AM ET


  1373. [12/01/2001] Beatle George Harrison Dies (E! Online)
    ...In June, he was treated at a Swiss clinic for a brain tumor, just months after checking into the Mayo Clinic to have a cancerous lung operated on....
    - Nov 30 4:23 AM ET


  1374. [12/01/2001] Today`s Health Highlights: Nov. 30, 2001 (HealthSCOUT)
    ... diagnosed with lung cancer in 1997 and was treated in Switzerland earlier this year for a brain tumor, the AP said....
    - Nov 30 12:10 PM ET


  1375. [12/01/2001] Houstonians Remember Music Legend (KPRC Click2Houston.com)
    ...Harrison admitted there was more cancer and that it had spread to his brain.......Harrison finished radiation treatments in Switzerland for the brain tumor and said that there was no further need for treatment.......Large tumors are more difficult to treat successfully, according to doctors....
    - Nov 30 7:22 PM ET


  1376. [12/01/2001] He`s awake, alert with brain exposed (The Arizona Daily Star)
    ... sharp pain when the drill moved through the skull bone and hit the sensitive lining of his brain....... as the surgeon began the delicate and dangerous job of cutting out a cancerous tumor embedded deep in his brain.......~~~ the procedure is done only on the most dangerously located tumors, and on patients who can handle it....
    - Nov 30 3:42 AM ET


  1377. [11/27/2001] Oates to Have Surgery for Brain Tumor (AP)
    Former Texas Rangers manager Johnny Oates, diagnosed this month with a brain tumor, will undergo surgery Tuesday.
    - Nov 19 7:36 PM ET


  1378. [11/27/2001] Ex-Rangers Manager Oates Undergoes Brain Surgery (Reuters)
    Former major league manager Johnny Oates underwent surgery for a brain tumor Tuesday at Johns Hopkins Hospital and is listed in good condition.
    - Nov 20 9:04 PM ET


  1379. [11/27/2001] Ex-Manager Oates Has Brain Surgery (AP)
    Former major league manager Johnny Oates underwent surgery Tuesday for a brain tumor and was listed in good condition at Johns Hopkins Hospital.
    - Nov 21 9:55 AM ET


  1380. [11/27/2001] Radio Waves Destroy Kidney Cancer Tumors in Trials (Reuters)
    Destroying cancer tumors with the same energy used to send radio signals has shown promising results in nonsurgical patients, and may gain wider acceptance, researchers said on Tuesday.
    - Nov 27 12:17 PM ET


  1381. [11/12/2001] Introgen to Present at Annual BIO-Europe Conference (PR Newswire)
    ... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
    - Nov 12 4:00 AM ET


  1382. [11/09/2001] Ex-Rangers Manager Has Brain Tumor (AP)
    Former Texas and Baltimore manager Johnny Oates has been diagnosed with the most aggressive form of primary brain tumors.
    - Nov 09 12:42 PM ET


  1383. [11/09/2001] Harrison Out of the Hospital? (E! Online)
    George Harrison`s health remains a question mark, but media outlets are now reporting that the Quiet Beatle has quietly checked out of a New York hospital after undergoing treatment for a brain tumor.
    - Nov 09 8:09 PM ET


  1384. [11/08/2001] More Harrison Health Rumors Fly (E! Online)
    ... where was going to undergo stereotactic radiosurgery, a procedure that attacks tumors with large amounts of radiation. Today, the rest of the British media picked up the story,......Earlier this year he was treated at a Swiss clinic, reportedly for a brain tumor....
    - Nov 08 5:11 PM ET


  1385. [11/08/2001] Former Rangers Manager Oates Diagnosed with Brain Tumor (Reuters)
    Former Texas Rangers and Baltimore Orioles manager Johnny Oates has been diagnosed with a brain tumor and will undergo surgery at the end of the month in Virginia.
    - Nov 08 7:25 PM ET


  1386. [11/08/2001] Ex-Manager Oates Has Brain Tumor (AP)
    Former Texas manager Johnny Oates has been diagnosed with a brain tumor and will undergo surgery later this month.
    - Nov 08 7:16 PM ET


  1387. [11/08/2001] Ex-Rangers Manager Johnny Oates Has Brain Tumor (Reuters)
    Former Major League Baseball player and manager Johnny Oates has a brain tumor and will have surgery at the end of the month.
    - Nov 08 9:05 PM ET


  1388. [11/08/2001] Northland family taking 14-year-old son to Australia for brain surgery (Kansas City Star)
    ... Oakley and their son Daniel will head to Australia, where doctors plan to remove a grape-sized tumor from Daniel`s brain....
    - Nov 08 7:05 AM ET


  1389. [11/06/2001] New Device at Stanford Delivers Safer, Targeted Brain Tumor Treatment (Business Wire)
    A Stanford University Medical Center neurosurgeon is one of the first in the country to treat brain tumors with a new device for delivering aggressive intratumoral radiation -- radiation therapy that irradiates cancerous cells from within the tumor cavity.
    - Nov 06 8:07 PM ET


  1390. [11/06/2001] Children With Facial Paralysis Learn to Smile, Thanks to Plastic Surgeons (PR Newswire)
    ...It can also be acquired via head trauma, removal of facial or brain tumors, or laceration of a facial nerve....
    - Nov 06 9:30 AM ET


  1391. [11/01/2001] Cancer-Linked Gene Also Controls Stem Cells: Study (Reuters)
    A gene that helps suppress tumors also controls the proliferation of stem cells in the brains of mice, scientists have found. They say the discovery could help them better understand--and possibly treat--aggressive tumors of the brain and other types of cancer in humans.
    - Nov 01 5:44 PM ET


  1392. [11/01/2001] New Lance Armstrong Cancer Program to Offer Latest Shaped Beam Technology To Treat Tumors (PR Newswire)
    ... focused radiation therapy technology that enables physicians to treat tumors of the brain, head, neck, spine, liver, lung and prostate without harming surrounding healthy......By shaping a radiation beam to mirror the exact size and shape of the tumor, the radiation dosage can be administered more precisely....
    - Nov 01 4:59 AM ET


  1393. [11/01/2001] Introgen`s PTEN Gene Drug May Provide Colorectal Cancer Treatment (PR Newswire)
    Introgen Therapeutics, Inc. announced that INGN 251, its PTEN gene drug, inhibits human colorectal tumors in animals.
    - Nov 01 10:01 AM ET


  1394. [10/30/2001] Introgen Therapeutics Announces Third Quarter 2001 Results (PR Newswire)
    ... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
    - Oct 30 4:04 PM ET


  1395. [10/30/2001] The Children`s Hospital of Philadelphia Opens the Region`s First Comprehensive Center Devoted to Full Spectrum of Musculoskeletal Care (PR Newswire)
    ... as well focus on the treatment of children with spinal disorders, benign and malignant tumors, and brain injuries....
    - Oct 30 9:07 AM ET


  1396. [10/26/2001] Introgen Announces Earnings Conference Call (Business Wire)
    ... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
    - Oct 26 5:23 PM ET


  1397. [10/25/2001] US Survey: Teens Lack Epilepsy Awareness (Reuters)
    ... has been known to result from head trauma, and lead or alcohol poisoning, as well as from brain tumors and stroke....
    - Oct 25 5:22 PM ET


  1398. [10/25/2001] Introgen`s INGN 241 Gene Drug Demonstrates Tumor Growth Control (PR Newswire)
    ...First, how MDA-7 protein is regulated as tumors develop from benign moles to the full-blown skin cancer known as melanoma and secondly,......This study demonstrates that mda-7 is a key tumor suppressor gene whose function is lost as melanoma tumors grow more aggressively....... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer....
    - Oct 25 7:04 AM ET


  1399. [10/23/2001] Gene Associated With Cancer and Other Diseases Awarded Patent and Licensed By Introgen (PR Newswire)
    ... collaborated since 1998 in the identification and pre- clinical development of a number of tumor suppressor genes.......Adenoviral-PTEN significantly slows the growth of human tumors, grown in animal models....... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer....
    - Oct 23 7:03 AM ET


  1400. [10/22/2001] Introgen to Present at Techvest Healthcare Conference (PR Newswire)
    ... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
    - Oct 22 7:33 AM ET


  1401. [10/22/2001] Immune System Therapy Helps Skin Cancer Patients (Reuters)
    ... to boost the immune system of melanoma patients after they have had surgery to remove skin tumors.......The treatment is based on cells called tumor infiltrating lymphocytes (TILS) that produce a reaction against the cancer....... spread rapidly throughout the body, forming secondary tumors in the liver, lungs, bones and brain....
    - Oct 22 10:24 AM ET


  1402. [10/19/2001] Protein Gives Clue to MS, Other Diseases (Reuters)
    ...If scientists can harness the repair skills of the molecule, known as tumor necrosis factor-alpha (TNF-a), they may be able to develop new treatments for MS and other......--the thin, protective coating that insulates nerve fibers in the brain and spine....
    - Oct 19 1:48 PM ET


  1403. [10/18/2001] Thalidomide: Single-handed Cancer Fighter? (HealthSCOUT)
    ...After surgery to remove the first tumor, two other sores appeared nearby.......When an immune-stimulating vaccine didn`t shrink the new tumors, the man began taking 200 milligrams a day of thalidomide....... thalidomide and another cancer drug, temozolomide, could treat melanoma that had spread to the brain....
    - Oct 18 4:05 AM ET


  1404. [10/17/2001] Ex-Beatle Harrison to Release New Single (Reuters)
    ... recorded the song at home on Oct. 1, less than six months after undergoing radiotherapy for a brain tumor....
    - Oct 17 4:44 PM ET


  1405. [10/17/2001] Thalidomide Sends Melanoma Patient Into Remission (Reuters)
    ... blood cancer called myelodysplastic syndrome, and it is under study as a treatment for kidney, brain and lung cancers, as well as Kaposi`s sarcoma-...... Louis University School of Medicine in Missouri used the drug because of its recognized anti-tumor properties and because of their patient`s situation....... scientists believe the drug fights cancer by both cutting off the blood supply to tumors and by boosting the immune system`s response to the disease....
    - Oct 17 6:18 PM ET


  1406. [10/18/2001] Introgen Gene Therapy Featured in Abstract and Published in Circulation, Journal of the American Heart Association (PR Newswire)
    ... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
    - Oct 18 7:00 AM ET


  1407. [10/17/2001] Cell Repair Weakness a Brain Cancer Marker (HealthSCOUT)
    A weakened ability of certain cells to repair damage to their genetic material seems to be an important indicator of the risk of the brain cancer called glioma, a study finds.
    - Oct 17 1:13 PM ET


  1408. [10/16/2001] Research Highlights Comprehensive Cancer Care Conference 2001 October 19-21 (PR Newswire)
    ... dollars studying promising synthetic drugs to block the growth of blood vessels that feed tumors, many natural agents have anti-angiogenic properties....... botanicals and other natural compounds. 3:30 - 5 p.m., Potomac 1-2 Nutritional Treatment for Brain Cancer: Best Case Series (repeated Sunday, October 21, 11:30 a.m....... to improve the efficacy of conventional treatments and significantly prolong life for brain tumor patients....
    - Oct 16 3:50 PM ET


  1409. [10/17/2001] A Fireball, a Prayer to Die, Then a Hard Battle to Live (The New York Times)
    ...Manning had surgery to remove a benign brain tumor....
    - Oct 17 8:54 AM ET


  1410. [10/11/2001] New Family of Ten Cancer Related Genes Is Discovered By Researchers at The National Cancer Institute, The University of Texas` Southwestern Medical Center and M. D. Anderson Cancer Center (PR Newswire)
    ...Discovery of these tumor suppressor genes represents a joint collaborative effort by scientists at The University of...... have been incorporated into gene delivery systems and have blocked the growth of established tumors in animal models of lung cancer....... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer....
    - Oct 11 6:00 AM ET


  1411. [10/10/2001] Introgen to Present at UBS Warburg Annual Healthcare Conference (PR Newswire)
    ... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
    - Oct 10 7:31 AM ET


  1412. [10/09/2001] Introgen`s Vice President James Merritt Talks to `Current Drug Discovery` About Progress With INGN 201 (PR Newswire)
    ... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
    - Oct 09 7:32 AM ET


  1413. [10/05/2001] Gulf War Vets` Children Studied (AP)
    ...Likely birth defects included webbed digits, heart murmurs, chromosomal abnormalities and brain tumors, while excluding what the researchers considered developmental disorders,...
    - Oct 05 3:05 PM ET


  1414. [10/05/2001] Study Looks at Gulf War Vets` Children (AP)
    ...Likely birth defects included webbed digits, heart murmurs, chromosomal abnormalities and brain tumors, while excluding what the researchers considered developmental disorders,...
    - Oct 05 5:58 PM ET


  1415. [10/05/2001] Brain Surgery Software (KPIX)
    ... sight you don`t see every day: a ninety-foot-tall, 17-hundred pound anatomically correct human brain balloon. The colorful vessel launched this year`s "Congress of Neurological Surgeons......The software enables them to clearly identify sensitive structures such as tumors, blood vessels or nerves that may otherwise be difficult to see. Stefan Vilsmeier,...
    - Oct 05 9:00 PM ET


  1416. [10/04/2001] New York Times Television to Introduce New Episodes of Lifeline On Discovery Health Channel (Business Wire)
    ...Brain Storm: A look at epilepsy treatment options, including brain surgery and the controversial...... local listings) A Glimmer in the Eye: Retinoblastoma is a rare form of cancer that causes tumors inside the eye....
    - Oct 04 4:38 PM ET


  1417. [09/28/2001] N.Y. Hospital Fined for MRI Death (AP)
    ... fractured in July by the oxygen tank as he underwent an MRI exam following surgery to remove a brain tumor. The metal cylinder was pulled by the machine`s powerful magnet from the arms of a doctor...
    - Sep 28 5:38 PM ET


  1418. [09/26/2001] Country pride shouldn`t be passing fad (The Sporting News)
    ...On a personal note for Spikes, his dad Jimmie is at home battling a brain tumor in Sandersville, Ga....
    - Sep 26 1:22 PM ET


  1419. [09/25/2001] NeuroPhysics Installs First European Super Resolution Neurofocus System for Functional Brain Imaging At Southern General Hospitals` Institute of Neurological Sciences (Business Wire)
    NeuroPhysics Corporation has shipped and installed its first super resolution NeuroFOCUS(TM) functional brain imaging system to Southern General Hospitals` Institute of Neurological Sciences in Glasgow, Scotland.
    - Sep 25 8:16 AM ET


  1420. [09/19/2001] Childhood Sunburn Linked to Adult Skin Cancer Risk (Reuters)
    ...Using mice genetically engineered to produce human-like skin and tumors, researchers at the National Cancer Institute in Bethesda, Maryland,...... spread rapidly throughout the body, forming secondary tumors in the liver, lungs, bones or brain. ...
    - Sep 19 5:11 PM ET


  1421. [09/20/2001] Optivus Technology is a Leading Candidate for M.D. Anderson`s $100 Million Proton Beam Cancer Treatment Project (Business Wire)
    ... delivered specific to their target, normal tissue is spared, side effects are reduced and the tumor receives higher radiation....... homogeneous radiation to three-dimensional volumes such as those seen in various cancers, brain tumors and macular degeneration....
    - Sep 20 5:00 AM ET


  1422. [09/06/2001] Silicon Valley`s New Promise: Nanotechnology (KPIX)
    It can attack cancerous tumors. It can make humans live longer by fixing aging cells. It`s called nanotechnology.
    - Sep 06 3:16 PM ET


  1423. [09/07/2001] Drug That Sends Radiation to Tumors Up for Review (Reuters)
    ... could be the first treatment approved to use ``radioimmunotherapy`` to kill tumors....... sending radiation throughout the body intravenously, the treatment could seek and kill several tumor sites at once....... new application for Guilford Pharmaceuticals Inc.`s Gliadel Wafer, which is implanted in the brain to dissolve and release chemotherapy, for prolonging survival and maintaining function in patients...
    - Sep 07 9:43 AM ET


  1424. [09/06/2001] Introgen`s Anti-Cancer Therapy in Combination With Established Cancer Treatments Awarded Patent (PR Newswire)
    ... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
    - Sep 06 7:30 AM ET


  1425. [09/05/2001] Introgen`s p16 Cancer Therapeutic Receives Patent; Introgen Owns Exclusive Worldwide License From The University of Texas System (PR Newswire)
    ...The patent covers the inhibition of tumor growth using the p16 tumor suppressor gene encoded in an adenoviral vector when delivered via...... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
    - Sep 05 7:30 AM ET


  1426. [09/05/2001] British Firm Unveils Robot for Brain Operations (Reuters)
    No need to worry any longer about the surgeon`s hand shaking during delicate brain surgery -- intelligent robots are set to take over.
    - Sep 05 8:02 AM ET


  1427. [09/05/2001] Robot Unveiled for Brain Operations (Reuters)
    No need to worry any longer about the surgeon`s hand shaking during delicate brain surgery -- intelligent robots are set to take over.
    - Sep 05 8:03 AM ET


  1428. [08/30/2001] Researchers Study Cancer Secretions (AP)
    An aggressive form of brain cancer secretes a chemical that kills nearby cells and carves out a path for its own growth, say researchers studying the disease in rats.
    - Aug 30 5:01 PM ET


  1429. [08/30/2001] Researchers Study Cancer Chemicals (AP)
    An aggressive form of brain cancer secretes a chemical that kills nearby cells and carves out a path for its own growth, say researchers studying the disease in rats.
    - Aug 30 5:06 PM ET


  1430. [08/30/2001] Researcher Finds Way to Slow Spread of Brain Tumors (PR Newswire)
    A New York Medical College neurophysiologist is closer to proving a new and non-invasive treatment for patients with glioblastomas. These common and virulent brain tumors are actively killing normal brain tissue to support their own growth.
    - Aug 30 5:00 PM ET


  1431. [08/21/2001] Internal Report Probes MRI Death (AP)
    ... head by the flying metal tank July 27, when he was being examined after surgery to remove a brain tumor....
    - Aug 21 10:01 AM ET


  1432. [08/21/2001] Neurons Implanted in Stroke-Damaged Brain Tissue Show Function, Say University of Pittsburgh Researchers (PR Newswire)
    An imaging study of neurons implanted in damaged areas of the brains of stroke patients in the hopes of restoring function has shown the first signs of cellular growth, say University of Pittsburgh researchers.
    - Aug 21 8:30 AM ET


  1433. [08/20/2001] Obituaries in the News (AP)
    ... composer and conductor who worked on numerous hit television shows and movies, died Saturday of a brain tumor....
    - Aug 20 6:46 AM ET


  1434. [08/20/2001] Transplanted Cells Seem to Integrate Into Brain (Reuters)
    Nerve cells transplanted into stroke-damaged areas of the brain show signs of growing and integrating into the brain, according to a new study.
    - Aug 20 10:21 AM ET


  1435. [08/18/2001] Maureen Reagan Mourned at Service (AP)
    ... nine-month battle with skin cancer that had progressed from a melanoma diagnosis in 1996 to tumors in her hip and brain....
    - Aug 18 8:31 PM ET


  1436. [08/17/2001] Obituaries in the News (AP)
    ... world-record holder at 10,000 meters and an Olympic silver medalist in the event, died Wednesday of a brain tumor....
    - Aug 17 6:55 AM ET


  1437. [08/13/2001] Xenova: Interim Results Announcement 2001 (PR Newswire)
    ... innovative immunotherapeutic vaccine, is designed as a treatment for a broad range of solid tumors.......DISC-GMCSF delivers the gene for the expression of GM-CSF, a potent stimulator of anti-tumor immune responses, direct to the tumor site through the use of a disabled virus vector (DISC)...... the nicotine will bind to these antibodies, which are too large to cross the blood-brain barrier, thus reducing or removing the pleasurable stimulus which usually accompanies smoking....
    - Aug 13 6:26 PM ET


  1438. [08/13/2001] Geron Corporation Announcement: Kyowa Hakko Selects Telomerase Inhibitor Compound for Development (Business Wire)
    ... potent and specific telomerase inhibitory activity in vitro and exhibits significant anti-tumor activity against multiple types of human cancer cells.......In vivo studies in rodents demonstrated activity against human malignant glioblastoma (brain cancer)....... the most pathogenic features of cancer cells is their loss of growth control, which allows tumors to invade and grow in normal tissue, causing loss of organ function and in many cases,...
    - Aug 13 7:32 AM ET


  1439. [08/12/2001] Newsweek Cover: John McCain: My Battle With Skin Cancer (PR Newswire)
    ...One of the worst parts was that our kids first heard about the tumor on CNN....... sorry this is happening to you.` The cancer that had begun with melanoma was invading her brain....
    - Aug 12 11:24 AM ET


  1440. [08/08/2001] Uninsured Children Seven Times More Likely to Go Without Medical Care They Need (PR Newswire)
    ...She learned about the Illinois` KidCare program when her uninsured son, Kendall, was diagnosed with a brain tumor....
    - Aug 08 10:30 AM ET


  1441. [08/02/2001] Pharmacyclics Completes Patient Enrollment in Xcytrin Phase II Clinical Trial For Primary Brain Tumors (PR Newswire)
    Pharmacyclics, Inc. today announced the company has completed patient enrollment in a Phase II clinical trial to evaluate its lead investigational product, Xcytrin(R) Injection, for the potential treatment of glioblastoma multiforme, the most common primary central nervous system tumor in adults.
    - Aug 02 7:31 AM ET


  1442. [07/31/2001] Colts Sign QB Mark Rypien to Deal (Associated Press)
    ... but because his young son, Andrew, was suffering from a malignant brain tumor and his wife,...
    - Jul 31 8:05 PM ET


  1443. [07/31/2001] Colts Sign Mark Rypien to Deal (Associated Press)
    ... but because his young son, Andrew, was suffering from a malignant brain tumor and his wife,...
    - Jul 31 7:59 PM ET


  1444. [07/31/2001] Colts Sign Ex-Super Bowl MVP Rypien (Associated Press)
    ... but because his young son, Andrew, was suffering from a malignant brain tumor and his wife,...
    - Jul 31 11:40 PM ET


  1445. [07/29/2001] Maryland Biotech Companies Target Stem Cells (WJLA)
    Matthew Garr was 3 years old when he developed a large brain tumor.
    - Jul 29 6:52 PM ET


  1446. [07/29/2001] Garage sale raises money to fund surgery for ailing teen (Kansas City Star)
    ...Australia, where doctors plan to remove a grape-size tumor that causes multiple seizures each day.......The tumor, at the base of Daniel`s brain, also has stunted his development....
    - Jul 29 7:03 AM ET


  1447. [07/25/2001] Brain Surgery Possible Without Blood Transfusion (Reuters)
    Patients who object to blood transfusions for religious reasons may still be able to safely undergo brain or spinal surgery, researchers report. In a new study, patients who refused blood transfusions for religious reasons fared almost as well as ``control`` patients undergoing similar procedures who did have blood transfusions.
    - Jul 25 5:36 PM ET


  1448. [07/24/2001] More Fab Four Hits Album Under Discussion - Starr (Reuters)
    ... underwent surgery for lung cancer earlier this year and has also recently completed radiation therapy reportedly for a brain tumor....
    - Jul 24 7:41 PM ET


  1449. [07/24/2001] Another Beatles hits album under discussion - Starr (Reuters)
    ... underwent surgery for lung cancer earlier this year and has also recently completed radiation therapy reportedly for a brain tumor....
    - Jul 24 7:36 PM ET


  1450. [07/25/2001] Ringo: More Fab Four Hits Album Under Discussion (Reuters)
    ... underwent surgery for lung cancer earlier this year and has also recently completed radiation therapy reportedly for a brain tumor....
    - Jul 25 7:10 AM ET


  1451. [07/23/2001] Beatle Harrison Denies `Imminent Death` Reports (Reuters)
    ...The musician has acknowledged completing a recent course of radiation therapy at a clinic in Switzerland, reportedly for a brain tumor,...
    - Jul 23 5:33 PM ET


  1452. [07/24/2001] Ex-Beatle Harrison Says He Is OK (Associated Press)
    ...He issued a statement at the time telling his fans not to worry and refused to comment on reports that he was battling a brain tumor....
    - Jul 24 3:45 AM ET


  1453. [07/24/2001] Ex-Beatle George Harrison Feels OK (Associated Press)
    ...He issued a statement at the time telling his fans not to worry and refused to comment on reports that he was battling a brain tumor....
    - Jul 24 6:29 AM ET


  1454. [07/24/2001] American Shared Hospital Services Signs New Gamma Knife Contract With Bayfront Medical Center in St. Petersburg, Florida (Business Wire)
    ...-- a non-invasive treatment of malignant and benign brain tumors, vascular malformations and trigeminal neuralgia facial pain....
    - Jul 24 10:06 AM ET


  1455. [07/22/2001] Ex-Beatle Harrison ``knows he will die soon`` (Reuters)
    ...The 58-year-old musician has been treated for a brain tumor at a clinic in Switzerland,...
    - Jul 22 2:25 PM ET


  1456. [07/23/2001] GEORGE: I KNOW I`M DYING (PageSix.com)
    ... the gutsy ex-Beatle - who was recently treated for a brain tumor and lung cancer - is calm about his deteriorating...
    - Jul 23 2:07 AM ET


  1457. [07/23/2001] The Wolf Files: Golden Circus God Dies (ABCNEWS.com)
    ... July, Gebel-Williams underwent surgery to remove a brain tumor....
    - Jul 23 7:51 AM ET


  1458. [07/22/2001] The Wolf Files: Golden Circus God Dies (ABCNEWS.com)
    ... July, Gebel-Williams underwent surgery to remove a brain tumor....
    - Jul 22 7:13 AM ET


  1459. [07/22/2001] George Harrison `Knows He Will Die Soon` From Cancer (Reuters)
    ...The 58-year-old musician has been treated for a brain tumor at a clinic in Switzerland,...
    - Jul 22 11:03 AM ET


  1460. [07/21/2001] The Wolf Files: Golden Circus God Dies (ABCNEWS.com)
    ... July, Gebel-Williams underwent surgery to remove a brain tumor.......He died at his Venice, Fla., home of cancer Thursday....
    - Jul 21 2:52 PM ET


  1461. [07/20/2001] Direct Therapeutics Awarded Patent for Medical Injection Device (Business Wire)
    ... anti-cancer product designed for direct injection to brain and liver tumors....... of anti-cancer agents in water-miscible, organic, tumor-penetrating solvent vehicles....
    - Jul 20 1:02 PM ET


  1462. [07/20/2001] The Wolf Files: Golden Circus God Dies (ABCNEWS.com)
    ... July, Gebel-Williams underwent surgery to remove a brain tumor....
    - Jul 20 3:38 PM ET


  1463. [07/20/2001] Trainer Gunther Gebel-Williams Dies (Associated Press)
    ...Gebel-Williams underwent surgery to remove a brain tumor last July....
    - Jul 20 10:04 AM ET


  1464. [07/20/2001] The Wolf Files: Golden Circus God Dies (ABCNEWS.com)
    ... July, Gebel-Williams underwent surgery to remove a brain tumor....
    - Jul 20 10:39 AM ET


  1465. [07/20/2001] The Wolf Files: Golden Circus God Dies (ABCNEWS.com)
    ... July, Gebel-Williams underwent surgery to remove a brain tumor.......He died at his Venice, Fla home of cancer Thursday....
    - Jul 20 6:26 AM ET


  1466. [07/20/2001] Weird News: The Wolf Files (ABCNEWS.com)
    Famed Ringling Bros. and Barnum and Bailey Circus animal handler Gunther Gebel-Williams died from cancer at age 66.
    - Jul 20 2:52 AM ET


  1467. [07/19/2001] Gunther Gebel-Williams, Legendary Star of Ringling Bros. and Barnum & Bailey(R), Dies in His Florida Home (PR Newswire)
    Animal lovers and circus fans around the globe are today mourning the loss of Gunther Gebel-Williams, legendary star of Ringling Bros. and Barnum & Bailey(R), who died this morning in his Venice, Florida, home after a year-long battle with cancer.
    - Jul 19 3:25 PM ET


  1468. [07/19/2001] Trainer Gunther Gebel-Williams Dies (Associated Press)
    Gunther Gebel-Williams, the circus animal trainer who delighted ladies and gentlemen, children of all ages, during his three decades with the Greatest Show on Earth, died of cancer Thursday at 66.
    - Jul 19 6:13 PM ET


  1469. [07/18/2001] Merck Granted Additional Six Months of Marketing Exclusivity for Mevacor-R- (Business Wire)
    ... studies demonstrated that lovastatin crosses the blood-brain and placental barriers.......Tumor increases were not seen at 20 and 100 mg/kg/day,...
    - Jul 18 3:52 PM ET


  1470. [07/17/2001] Brain Tumor Medical Advice Nurse Only a Phone Call Away: (PR Newswire)
    A vital free service for brain tumor patients and their families is once again available through the National Brain Tumor Foundation. The twenty-year-old agency`s Medical Advice Nurse has again been funded by the Tim & Tom Gullikson Foundation.
    - Jul 17 12:58 PM ET


  1471. [07/18/2001] Seniors will suffer as HMOs cut back (Detroit Free Press)
    Joan Ellery has a failing heart and is partially paralyzed from a brain tumor. Her husband, Bernard, a retired tool-and-die worker, has glaucoma and heart problems. He hasn`t worked since his 1990 colon cancer surgery.
    - Jul 18 6:37 AM ET


  1472. [07/17/2001] First and Final Add -- Nytu032 -- Pfizer Inc (NYSE: Pfe) (PR Newswire)
    ... cause of death in the U.S., behind heart diseases and cancer,...... meningitis is a life-threatening infection of the brain caused by the yeast Cryptococcus neoformans;...
    - Jul 17 6:38 AM ET


  1473. [07/16/2001] Experts Say Stem Cells Promise Medical Revolution (Reuters)
    ... disease, injecting stem cells into the area of the brain that controls muscle movement,...... by providing skin grafts; spinal cord injuries; and cancer patients who have lost cells and tissue to radiation...
    - Jul 16 2:21 PM ET


  1474. [07/13/2001] Maureen Reagan`s Cancer Spreads to Her Brain (PR Newswire)
    Maureen Reagan, the daughter of former President Ronald Reagan and actress Jane Wyman, has been re-hospitalized at Mercy San Juan Hospital in Carmichael, California, and is undergoing whole brain radiation for malignant melanoma that has spread to her brain.
    - Jul 13 6:00 AM ET


  1475. [07/13/2001] Maureen Reagan`s Cancer Spreads (Associated Press)
    Maureen Reagan, the eldest daughter of former President Reagan, is undergoing radiation treatments for melanoma that has spread to her brain, her husband said Friday.
    - Jul 13 6:00 PM ET


  1476. [07/13/2001] Brain Cancer Vaccine Under Way (KGTV TheSanDiegoChannel.com)
    Brain tumors are one of the fastest growing cancers today.
    - Jul 13 6:23 PM ET


  1477. [07/10/2001] American Shared Announces Conference Call to Discuss Second Quarter Results On July 17 at 11:00 AM PDT (Business Wire)
    ...The Gamma Knife treats certain malignant and benign brain tumors,...
    - Jul 10 11:08 AM ET


  1478. [07/09/2001] Harrison`s Latest Cancer Scare (E! Online)
    George Harrison says he`s ~~~feeling fine~~~ amid reports he`s battling brain cancer, but the Quiet Beatle remains mum on specifics.
    - Jul 09 2:38 PM ET


  1479. [07/09/2001] Ex-Beatle Recovering From Radiation (Associated Press)
    George Harrison, the 58-year-old former Beatle who has been battling cancer, said Monday he`s ``feeling fine`` after radiation treatment and that his fans shouldn`t worry over reports that he has a brain tumor.
    - Jul 09 3:08 PM ET


  1480. [07/09/2001] Ex-Beatle Harrison Says `I Feel Fine` (Reuters)
    ... reported on Sunday that Harrison had been treated for a brain tumor at the hospital....
    - Jul 09 10:33 AM ET


  1481. [07/09/2001] Ex-Beatle Recovering From Radiotherapy (Associated Press)
    ... specialist Franco Cavalli was treating Harrison for a brain tumor....
    - Jul 09 10:59 AM ET


  1482. [07/09/2001] Report: Ex-Beatle Treated for Tumor (Associated Press)
    Former Beatle George Harrison is reportedly being treated for a brain tumor in Switzerland - just two months after receiving lung cancer therapy in the United States.
    - Jul 09 5:05 AM ET


  1483. [07/05/2001] Armstrong Hopes for Clean Tour (Associated Press)
    ... victory, which marked a comeback from advanced testicular cancer....... than a 40 percent chance of survival, he underwent brain surgery and chemotherapy and had a testicle removed....
    - Jul 05 7:26 PM ET


  1484. [07/05/2001] Armstrong Hopes for Clean Tour (Associated Press)
    ... victory, which marked a comeback from advanced testicular cancer....... than a 40 percent chance of survival, he underwent brain surgery and chemotherapy and had a testicle removed....
    - Jul 05 5:30 PM ET


  1485. [07/02/2001] Guitar Great Chet Atkins Dead (E! Online)
    ... 1970s and in June 1997 underwent surgery to have a brain tumor rumored. Dubbed Nashville`s ~~~Mr....
    - Jul 02 3:47 PM ET


  1486. [07/02/2001] SkyePharma and Nippon-Shinyaku Announce Distribution Agreement For DepoCyt(TM) in Japan (PR Newswire)
    ... need for surgical insertion of a reservoir into the brain that is often necessary for frequent administration......Prevalence is dependent on tumor type and is estimated at up to 25% of patients with...... estimated at up to 25% of patients with late-stage solid tumors and up to 20% of patients with certain types of lymphoma....
    - Jul 02 7:30 AM ET


  1487. [06/30/2001] Guitarist Chet Atkins Dies at 77 (Associated Press)
    ...He underwent surgery to remove a brain tumor in June 1997,...
    - Jun 30 6:49 PM ET


  1488. [06/30/2001] Obituaries in the News (Associated Press)
    ...He underwent surgery to remove a brain tumor in June 1997,...
    - Jun 30 9:37 PM ET


  1489. [06/28/2001] Healthcast: New Aneurysm Surgery Scars Less (WTAE ThePittsburghChannel.com)
    If brain aneurysms are found early, they can now be removed without leaving much of a scar, WTAE-TV medical editor Marilyn Brooks reports.
    - Jun 28 4:39 PM ET


  1490. [06/29/2001] British Boy Improves After Australia Brain Surgery (Reuters)
    A nine-year-old British boy who had a brain tumor removed in Australia was set to leave hospital on Friday, his parents encouraged by early signs 10 days after the rare surgery to stop his epileptic seizures.
    - Jun 29 3:43 AM ET


  1491. [06/28/2001] Tressel`s countdown to Nov. 24 continues (The Sporting News)
    ... involved right now in a heck of a battle with his wife`s cancer.......In fact, I picked his brain quite a bit in the last month....
    - Jun 28 1:17 PM ET


  1492. [06/28/2001] Lance Armstrong Rides a Cycle of Hope(TM) for Cancer Patients (PR Newswire)
    Two-time Tour de France champion and cancer survivor Lance Armstrong today issued a call to action to every American to ~~~know your cancer risks and get screened~~~ through his national cancer awareness campaign, the Cycle of Hope(TM), just days before he is set to defend his title in the 2001 Tour de France.
    - Jun 28 7:01 AM ET


  1493. [06/28/2001] MacroChem Highlights Topical Erectile-Dysfunction Drug Study, Topical Testosterone Drug at Annual Meeting (PR Newswire)
    ... who avoided Viagra due to prior surgery for a benign brain tumor,...
    - Jun 28 10:00 AM ET


  1494. [06/27/2001] Bio-logic Systems Names Robert Sciote Vice President Hearing Business North America (PR Newswire)
    ... in the diagnosis of certain neurological disorders, brain disorders and tumors,...
    - Jun 27 8:00 AM ET


  1495. [06/25/2001] Critic Siegel Undergoes Surgery (Associated Press)
    ...Siegel, whose first wife died of a brain tumor in 1982,...
    - Jun 25 3:13 PM ET


  1496. [06/24/2001] Brain surgery spares intricacies of the mind (Baltimore Sun)
    It was quietly growing in 18-year-old Robyn Kirby`s brain for years, maybe even for most of her life, while she mothered her younger cousins, shouted from the lifeguard chair and banged hockey sticks on Catonsville streets with neighborhood boys.
    - Jun 24 7:11 AM ET


  1497. [06/22/2001] British Boy Stable After Brain Surgery in Australia (Reuters)
    A nine-year-old British boy who had a brain tumor removed in Australia was in stable condition three days after the rare surgery to stop his epileptic seizures.
    - Jun 22 4:31 AM ET


  1498. [06/20/2001] Healthcast: Minimally Invasive Brain Surgery (WTAE ThePittsburghChannel.com)
    A brain surgery is available that is minimally invasive and is less traumatic than traditional brain surgery.
    - Jun 20 6:56 PM ET


  1499. [06/19/2001] ~~~Silly little virus~~~ may cure brain cancer -study (Reuters Securities)
    An innocuous virus commonly found in the human body shows great promise as a potential cure for a ferocious form of brain cancer in a novel strategy pitting virus against tumor, researchers said on Tuesday.
    - Jun 19 5:14 PM ET


  1500. [06/19/2001] `Silly Little Virus` May Cure Brain Cancer -Study (Reuters)
    An innocuous virus commonly found in the human body shows great promise as a potential cure for a ferocious form of brain cancer in a novel strategy pitting virus against tumor, researchers said on Tuesday.
    - Jun 19 5:29 PM ET


  1501. [06/19/2001] British Boy Has Rare Brain Surgery in Australia (Reuters)
    Australian doctors successfully removed a tumor from a nine-year-old British boy`s brain Tuesday in a rare operation to stop the boy`s epileptic seizures.
    - Jun 19 7:21 AM ET


  1502. [06/17/2001] Chicago Sportscaster Tim Weigel Dies (Associated Press)
    ...Tim Weigel was diagnosed with the brain tumor last year and had his first surgery on Father`s Day last June, after tests showed a lesion on his brain....
    - Jun 17 8:19 PM ET


  1503. [06/17/2001] Sports Director Tim Weigel Dies Today After A Courageous Fight Against Cancer (PR Newswire)
    Tim Weigel, CBS 2 CHICAGO sports director, passed away today at 5:20 AM at his home in Evanston, from a malignant brain tumor.
    - Jun 17 7:14 PM ET


  1504. [06/14/2001] NewsRx Announces New Publisher, Editor-In-Chief, Key Staff (Internet Wire)
    ...Formerly, she was with the University of North Carolina School of Medicine, Texas Children`s Hospital, and the University of Texas M.D. Anderson Cancer Center.......NewsRx.net serial titles are monthly, quarterly and annual reports on: AIDS and HIV, AIDS and HIV Adverse Drug Effects, AIDS and HIV Animal Models, AIDS and HIV Blood Safety, AIDS and HIV Cancer, AIDS and HIV Co-infection, AIDS and HIV Cytomegalovirus, AIDS and HIV Depression, AIDS and HIV Dermatology, AIDS and HIV Drug Resistance, AIDS and HIV Funding, AIDS and HIV Genetic, AIDS and HIV Human Papillomavirus, AIDS and HIV Mycobacterium Avium, AIDS and HIV Pathogenesis, AIDS and HIV Pediatric, AIDS and HIV Prophylaxis, AIDS and HIV Public Health, AIDS and HIV Testing, AIDS and HIV Transmission, AIDS and HIV Tuberculosis, AIDS and HIV Vertical Transmission, AIDS and HIV Viral Load, AZT, Abciximab, Abdominal, Abortion, Abortion Issues, Ace Inhibitor, Acetaminophen, Acid Reflux, Acupuncture, Acute Hepatitis, Acute Myocardial Infarction, Addiction Medicine, Adenoviral Vector, Adenovirus, Adiposity, Adjuvant, Adolescent Health, Adoptive Immunotherapy, Adrenergic, Adverse Drug Effects, Age-Related Macular Degeneration, Aging, Alcoholism, Allergic Rhinitis, Allergy Medicine, Allograft, Alzheimer`s Disease, Amyloid, Analgesia, Anemia, Anesthesia, Angina, Angiogenesis, Angiogenic, Angiology, Angiology Prognosis, Angioplasty, Angiotensin, Animal Models, Animal Studies, Anorexia, Anthrax, Antibiotic Resistance, Antidepressant, Antifungal, Antihistamine, Antimicrobial Resistance, Antioxidant, Antisense Technology, Antiviral, Anxiety Disorder, Apolipoprotein, Apoptosis, Arthritis Risk Factors, Arthritis Therapy, Asthma, Atherosclerosis, Atrial Fibrillation, Attention Deficit Hyperactivity Disorder, Autism, Autoimmune Disease, Autoimmunity, Autologous, Back Pain, Bacterial Meningitis, Bacteriology, Behavioral Medicine, Bile, Biliary, Biocompatibility, Bioengineering, Bioinformatics, Biological Weapon, Biomarkers, Biomaterial, Biomedicine, Biotechnology, Bioterrorism, Bipolar Disorder, Birth Defects, Bladder Cancer, Blood Banking, Blood Donation, Blood Glucose, Blood Pressure, Blood Product, Blood Safety, Blood Testing, Blood Vessel, Body Composition, Body Mass Index, Bone Density, Bone Fracture, Bone Marrow, Bone Marrow Transplantation, Botulinum Toxin, Botulism, Bovine Spongiform Encephalopathy, Bowel Disease, Brachytherapy, Brain Cancer, Brain Development, Brain Metastases, Breast Cancer, Breathing Disorders, Bronchitis, Burn Care, Cancer Immunotherapy, Cancer Pain, Cancer Research, Cancer Survival and Mortality, Cannabinoids, Carcinogenesis, Cardiac Arrest, Cardiology, Cardiomyocyte, Cardiomyopathy, Cardiopulmonary, Cardiopulmonary Bypass, Cardiovascular, Cardiovascular Abnormalities, Cardiovascular Health, Caregiving, Carotid Artery, Cataracts, Catheterization, Cell Biology, Cell Transplantation, Cervical Cancer, Cesarean, Chemokines, Chemotherapy, Chest Pain, Chickenpox, Chlamydia, Cholera, Cholesterol, Chronic Disease, Chronic Heart Failure, Chronic Illness, Chronic Liver Disease, Chronic Lung Disease, Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease Clinical Tri, Chronic Pain, Cirrhosis, Cisplatin, Cleft Lip, Cleft Lip and Palate, Clinical Trials, Cloning, Clostridium, Clostridium difficile, Cluster Headache, Coagulation, Cochlear Implant, Cognition, Coinfection, Coinfection (HIV and TB), Colitis, Collagen, Colon Cancer, Colonoscopy, Colorectal, Colorectal Cancer, Colorectal Cancer Surgery, Common Cold, Comorbidity, Complementary and Alternative Medicine, Compliance, Condoms, Congestive Heart Failure, Constipation, Contraception, Cord Blood, Coronary Angioplasty, Coronary Artery, Coronary Bypass, Correctional Healthcare, Corticosteroid, Creutzfeldt-...
    - Jun 14 9:00 PM ET


  1505. [06/13/2001] MDX Medical Reports Addition of Investor Relations Director (CCN Newswire)
    ...improving the safety and accuracy of radio-surgery for patients with brain tumors....
    - Jun 13 12:31 PM ET


  1506. [06/06/2001] Former Minnesota goaltender Killewald diagnosed with brain tumor (U-Wire)
    In her four years with the Minnesota women`s hockey team, former goaltender Erica Killewald faced some tough opponents.
    - Jun 06 7:04 PM ET


  1507. [06/07/2001] UNC Surgeon Restores Vivacious 4-Year-Old After Removing Brain Tumor (PR Newswire)
    A.J. Pennywell of Wake Forest, N.C. was a ~~~normal, rambunctious 4-year-old,~~~ his mother said, before his brain tumor grew large enough to start causing symptoms.
    - Jun 07 7:01 AM ET


  1508. [06/06/2001] Guilford`s Supplemental New Drug Application for GLIADEL(R) Wafer Accepted For Review by the FDA (PR Newswire)
    ...The first new therapy to be approved for the treatment of brain cancer in over two decades, GLIADEL® Wafer received marketin......GLIADEL® Wafers can be implanted in the cavity created when a brain tumor is surgically removed....
    - Jun 06 10:41 AM ET


  1509. [06/06/2001] British Boy in Australia for Rare Brain Surgery (Reuters)
    A nine-year-old British boy has flown half away around the world with his parents to undergo ground-breaking surgery in Australia in the hope of stopping epileptic seizures caused by a brain tumor.
    - Jun 06 4:03 AM ET


  1510. [06/05/2001] New Data Evaluating Up to Seven Years of Treatment Reaffirms Long-Term Benefits of Proscar(R) in Men with BPH (PR Newswire)
    ...substance that is measured in a common blood test to screen for prostate cancer.......Finasteride has been shown to cross the blood brain barrier but does not appear to distribute preferentially to the ...
    - Jun 05 5:43 PM ET


  1511. [06/05/2001] Korn, Kid Rock, Slipknot Reach Out To Ailing Death Frontman (SonicNet)
    ...Chuck Schuldiner, of the band Death, has been battling a malignant brain tumor for two years, and is currently undergoing expensive exper......~~~When I found out Chuck had cancer I was freaking....
    - Jun 05 6:47 PM ET


  1512. [06/05/2001] Introgen Therapeutics and the University of California Collaborate to Study Gene Therapy Approaches to Arthritis (PR Newswire)
    ...This discovery established the concept of using therapies based upon tumor suppressor genes to treat rheumatoid arthritis and potentially o......additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......candidate, INGN 241 (Adenoviral-mda7), for the treatment of solid tumors, is in Phase I clinical development....
    - Jun 05 7:30 AM ET


  1513. [06/01/2001] `Miracles: One At A Time` By: Andy Andrews (PR Newswire)
    ...devastated that the chemotherapy treatments he would get for bone cancer would make his hair fall out.......Another missive came from a girl who had half her brain removed at age 14 due to a regenerative brain disease....
    - Jun 01 5:20 AM ET


  1514. [05/30/2001] Surgery Gives Voice to Speechless Man (Reuters)
    ...old man of the same tissue type as Heidler who died from a ruptured brain aneurysm.......Monaco, who himself lost his larynx to cancer, said as anti-rejection drugs become safer and more effective, `...
    - May 30 6:19 PM ET


  1515. [05/31/2001] Man With Transplanted Voice Box Speaking Normally (ABCNEWS.com)
    ...Could Help Cancer Patients And ABCNEWS` Dr. Tim Johnson said that success is good ......Cincinnati who had died suddenly when a blood vessel ruptured in his brain.A New Voice The doctors replaced his larynx or voice box, along ...
    - May 31 8:52 AM ET


  1516. [05/28/2001] Procedure Offers Facial Pain Relief (KGTV TheSanDiegoChannel.com)
    ...doctors around the country are finding the same technology commonly used to treat brain tumors can also treat trigeminal neuralgia....
    - May 28 6:39 PM ET


  1517. [05/29/2001] Accelerated Breast Cancer Treatment Successfully Completes Clinical Trial (PR Newswire)
    ...The procedure irradiates the area surrounding the cavity created by the lumpectomy, where tumors are most likely to recur, and can avoid the side effects of external beam therapy.......Inc. is a privately held medical device company established in 1995 to develop site-specific cancer treatment systems for breast and brain tumors....
    - May 29 8:31 AM ET


  1518. [05/24/2001] Sagemark Companies to Open PET Imaging Center (Business Wire)
    ...~~~PET scanning is a revolutionary medical diagnostic imaging technology that enables physicians to pinpoint and accurately diagnose life threatening cancers as well as a variety of brain disorders, including Alzheimer`s Disease, Parkinson`s Disease and a variety of seizure disorders including epilepsy.......PET provides physicians with important early detection information about such diseases and is the most accurate non-invasive procedure currently available to determine whether or not a tumor is malignant or benign....
    - May 24 8:23 AM ET


  1519. [05/21/2001] The Head-to-Toe High-Tech Checkup (SmartMoney.com)
    ...a full-body computed tomography scan (also known as a CT scan) and a magnetic resonance imaging, or MRI, check of the brain Dr. Daniel Cosgrove at the Palm Springs, Calif., clinic detected a problem with Spivock`s mitral valve,......this test can also be used to view your lungs and check for questionable tumors or lesions.......And because of its sensitivity, it can also detect lung cancer years before a tumor will show up on a traditional chest X-ray or sputum test....
    - May 21 6:45 PM ET


  1520. [05/21/2001] Researchers Use Polio Virus to Kill Brain Tumors (Reuters)
    A hybrid of the virus that causes polio and the virus that causes the common cold could eliminate the most common type of brain cancer, researchers said on Monday in a finding that might offer new hope for the growing number of patients with the fatal disease.
    - May 21 8:33 AM ET


  1521. [01/02/2001] $14.3 Million Federal Grant Fuels Cardiovascular Gene Therapy Program At University Of Pittsburgh (US Newswire)
    ...clinical investigators have applied this technology to problems ranging from heart disease to cancer.......Clinical trials have included novel therapies for an inherited metabolic disorder and for cancers of the breast and brain....
    - Jan 02 11:00 AM ET


  1522. [05/20/2001] Lerner`s prognosis `excellent` (Akron Beacon Journal)
    Browns owner Al Lerner had a pituitary tumor treated during a medical procedure at the Cleveland Clinic last week, according to a source familiar with the procedure.
    - May 20 6:37 AM ET


  1523. [05/18/2001] Browns Owner Visits Practice (Associated Press)
    Cleveland Browns owner Al Lerner met with coaches and players at the team`s practice facility Friday, just a few days after having brain surgery.
    - May 18 8:11 PM ET


  1524. [05/18/2001] Vukovich to have limited coaching role during radiation treatments (AP)
    Phillies third base coach John Vukovich faces radiation treatments and a limited coaching role for the next six weeks as he recovers from surgery for the partial removal of a benign brain tumor.
    - May 18 6:37 PM ET


  1525. [05/18/2001] Phillies Coach Treating Cancer (Associated Press)
    Phillies third base coach John Vukovich faces radiation treatments and a limited coaching role for the next six weeks as he recovers from surgery for the partial removal of a benign brain tumor.
    - May 18 6:36 PM ET


  1526. [05/17/2001] American Shared Hospital Services` 12th Gamma Knife Center Opens at OSF Saint Francis Medical Center in Peoria (Business Wire)
    ...OSF Saint Francis is American Shared`s third Gamma Knife unit for non-invasive brain surgery procedures to open in 2001.......American Shared remains the leader in the ownership of non-invasive Gamma Knife radiosurgery units and continues to extend the Gamma Knife as the surgical alternative of choice for certain small-to-medium sized intracranial malignant and benign brain tumors, vascular malformations and trigeminal neuralgia....
    - May 17 4:03 PM ET


  1527. [05/17/2001] Study: 1 In 5 May Have Pituitary Disorder (WRTV TheIndyChannel.com)
    ...Three years passed before a doctor told her that she had a benign tumor on her pituitary gland.......~~~ Judelson said.A recent study released by the American Association of Clinical Endocrinologists shows that one in five adults may have a tumor - usually a benign one - on the gland, which is located at the base of the brain....
    - May 17 7:05 PM ET


  1528. [05/17/2001] Browns Owner Home After Surgery (Associated Press)
    Cleveland Browns owner Al Lerner has returned home following brain surgery.
    - May 17 8:58 PM ET


  1529. [05/17/2001] Browns Owner Home After Surgery (Associated Press)
    Owner Al Lerner of the Cleveland Browns has returned home after brain surgery, a spokesman said.
    - May 17 9:02 AM ET


  1530. [05/15/2001] Introgen Reports Significant Increase in Responses to Combination Therapy For Phase II Lung Cancer Study (PR Newswire)
    ...Three patents cover gene therapy of cancer using a p53 tumor suppressor gene in combination with one or more chemotherapeutic drugs,......Introgen is also conducting a Phase II clinical trial for INGN 201 in lung cancer and Phase I trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......INGN 241 (Adenoviral-mda7), for the treatment of solid tumors, is in Phase I clinical development....
    - May 15 10:45 AM ET


  1531. [05/15/2001] Young Detroiters Who Have Pursued Their Education Despite Huge Challenges to be Honored Wednesday, May 16, by Detroit City Council (PR Newswire)
    ...Mario was in 4th grade when doctors found a tumor on his brain which causes seizures....
    - May 15 11:10 AM ET


  1532. [05/15/2001] Phillies Coach Returns After Surgery (Associated Press)
    Phillies third-base coach John Vukovich returned to Veterans Stadium on Tuesday, one week after surgery to remove part of a benign tumor from his head.
    - May 15 8:24 PM ET


  1533. [05/13/2001] Allos Therapeutics Reports Positive Results From Phase II Study of RSR13 For Non-Small Cell Lung Cancer at ASCO (PR Newswire)
    ...The rationale for using induction chemotherapy in locally advanced non-small cell lung cancer is that chemotherapy may prevent the growth of systemic disease and, concurrently, reduce the local tumor involvement in the lungs and chest which may then be better treated with surgery,......The Company also announced plans to increase the number of patients enrolled in its ongoing Phase III randomized study of RSR13 combined with standard whole brain radiation therapy versus standard whole brain radiation therapy alone for the treatment of patients with brain metastases.......The Company has initiated its first pivotal Phase 3 trial for the treatment of metastatic brain tumors with its lead clinical candidate, RSR13....
    - May 13 7:49 PM ET


  1534. [05/14/2001] Docetaxel After Chemoradiotherapy Shows Highest Survival Rate Ever In Non-Small Cell Lung Cancer Patients (PR Newswire)
    ...In 15 cases, the first site of disease relapse was the brain, suggesting the development of a ``sanctuary site`` in the brain,......Tumor regression has been reported in lung cancer patients treated with the compound....
    - May 14 8:06 AM ET


  1535. [05/13/2001] New Data Suggest Novartis Drug Gleevec(TM) (Formerly STI571) Effective In Rare Form of Gastrointestinal Tumor (PR Newswire)
    Novartis Oncology today announced that data on the activity of Gleevec(TM) in a rare form of gastrointestinal stromal tumor will be highlighted during the key plenary session of the 37th annual meeting of the American Society for Clinical Oncology in San Francisco, California.
    - May 13 12:00 PM ET


  1536. [05/09/2001] EpiGenX Rounds Out Scientific Advisory Board with Nobel Laureate (Business Wire)
    ...and is a leading expert in the field of methylation, including identifying non-random and tumor-specific methylation patterns in human malignancies.......Dr Costello is a member of the Brain Tumor Research Center at UCSF and has had his work featured in editorials published in Nature Genetics,...
    - May 09 11:26 AM ET


  1537. [05/09/2001] Microvision Reports First Quarter Results (PR Newswire)
    ...Nomad`s capability for displaying images overlaid onto the patient will be tested to determine if augmented vision capability would aid the surgeon and attendants who require an enhanced `inside the body` view during such procedures as catheter stent placement, radiation treatment of prostate tumors, brain surgery and anesthesiology monitoring....
    - May 09 6:30 AM ET


  1538. [05/08/2001] Phillies Coach Has Tumor Removed (Associated Press)
    Phillies third-base coach John Vukovich underwent surgery Tuesday to remove part of a benign tumor from his head.
    - May 08 4:04 PM ET


  1539. [05/09/2001] Vukovich undergoes surgery for brain tumor (Philadelphia Daily News and Inquirer)
    Phillies third-base coach John Vukovich was reported in excellent condition yesterday after he had a portion of a benign tumor removed from his brain at Thomas Jefferson University Hospital.
    - May 09 7:54 AM ET


  1540. [05/07/2001] EpiGenX Rounds Out Scientific Advisory Board with Nobel Laureate (Business Wire)
    ...and is a leading expert in the field of methylation, including identifying non-random and tumor-specific methylation patterns in human malignancies.......Dr Costello is a member of the Brain Tumor Research Center at UCSF and has had his work featured in editorials published in Nature Genetics,...
    - May 07 11:40 AM ET


  1541. [05/08/2001] AstraZeneca Completes Enrollment in Phase III Non-Small Cell Lung Cancer Clinical Trial Program For IRESSA(R) (ZD1839) (PR Newswire)
    ...Clinical studies are ongoing regarding the use of IRESSA for other solid tumors.......The National Cancer Institute (NCI) or oncology cooperative groups are accruing patients into clinical trials with IRESSA in renal cell, bladder, glioblastoma and brain cancers.......Expression and overexpression of EGFR is found in many tumor types and clinical data suggests that excessive levels of EGFR are linked to poor prognosis,...
    - May 08 10:38 AM ET


  1542. [05/08/2001] National Brain Tumor Foundation Recognizes Pharmacyclics and Schering-Plough With Merit Award for Advancing Brain Tumor Research (PR Newswire)
    The National Brain Tumor Foundation announced today that its first annual Award of Merit will be given jointly to Pharmacyclics, Inc. and Schering-Plough Corporation for their contributions and ongoing commitment to researching and developing treatments for brain tumors.
    - May 08 7:30 AM ET


  1543. [05/08/2001] Pharmacyclics Receives National Brain Tumor Foundation`s Award of Merit for Advancing Brain Tumor Research (PR Newswire)
    Pharmacyclics, Inc. announced today that The National Brain Tumor Foundation has given its first annual Award of Merit jointly to Pharmacyclics, Inc. and Schering-Plough Corporation for their scientific and clinical contributions and ongoing commitment to researching and developing treatments for brain tumors.
    - May 08 7:31 AM ET


  1544. [05/08/2001] Proxima Therapeutics Announces FDA Approval of GliaSite(R) Radiation Therapy System for Brain Tumors (PR Newswire)
    Proxima Therapeutics Inc., a developer and marketer of site-specific cancer treatments, today announced that its GliaSite Radiation Therapy System treatment for brain tumors has received marketing clearance from the United States Food and Drug Administration, its first product to receive FDA approval.
    - May 08 8:05 AM ET


  1545. [05/07/2001] PoleStar N-10 From Odin Medical Technologies Improves Brain Tumor Surgery (Business Wire)
    A breakthrough in intraoperative Medical Resonance Imaging technology is offering new hope to the more than 185,000 men, women and children in the United States who are diagnosed each year with a brain tumor.
    - May 07 7:05 AM ET


  1546. [05/07/2001] National Brain Tumor Awareness Week 2001; Innovative Wafer Therapy Has Enhanced Treatment Options, Renewed Hope (PR Newswire)
    This year more than 185,000 Americans will be diagnosed with primary or metastatic brain tumors, now the leading cause of solid tumor cancer death in children younger than age 20, and the third leading cause of cancer death in young adults between the ages of 20 to 39.
    - May 07 8:32 AM ET


  1547. [05/04/2001] New Cancer Drug Shows Promise (WISN TheMilwaukeeChannel.com)
    ...~~~Carol was diagnosed with gastrointestinal stromal tumors or GIST.......Berrus had surgery, removing most of her stomach, to get rid of her tumor.......Glivec has also been used to treat some forms of leukemia and brain cancer....
    - May 04 7:56 PM ET


  1548. [05/05/2001] Epilepsy: The Hidden Disability (HealthSCOUT)
    ...the second-most common neurological disorder of the brain.......Anything that damages the central nervous system, from a brain tumor to a serious head injury like Gazaway`s, can cause epilepsy....
    - May 05 3:03 AM ET


  1549. [05/03/2001] American Shared Hospital Services` 11th Gamma Knife Center Opens At Central Mississippi Medical Center (Business Wire)
    ...CMMC is American Shared`s second Gamma Knife unit for non-invasive brain surgery procedures to open in 2001.......The Gamma Knife treats certain malignant and benign brain tumors, vascular malformations and trigeminal neuralgia without invasive surgery....
    - May 03 5:00 AM ET


  1550. [05/03/2001] Visualization Technology Introduces Specialized Software for Neurosurgery (Business Wire)
    Visualization Technology, Inc. announced today the release of a highly advanced software application for use in cranial surgery. Used in conjunction with the InstaTrak(R) System for image guided surgery, Auto Segmentation(TM) is a sophisticated software tool that enables the neurosurgeon to quickly isolate and color code critical structures such as tumors and blood vessels using a scan of a patient`s brain.
    - May 03 2:25 PM ET


  1551. [05/03/2001] American Shared Hospital Services` 11th Gamma Knife Center Opens At Central Mississippi Medical Center (Business Wire)
    ...CMMC is American Shared`s second Gamma Knife unit for non-invasive brain surgery procedures to open in 2001.......The Gamma Knife treats certain malignant and benign brain tumors, vascular malformations and trigeminal neuralgia without invasive surgery....
    - May 03 5:00 AM ET


  1552. [05/01/2001] JPMorgan H&Q CEO Resigns (AP Financial)
    ...underwent surgery five weeks ago to remove a malignant brain tumor....
    - May 01 2:30 PM ET


  1553. [05/01/2001] JPMorgan H&Q CEO Resigns (Associated Press)
    ...underwent surgery five weeks ago to remove a malignant brain tumor....
    - May 01 2:30 PM ET


  1554. [04/27/2001] Brain, Lung Cancers Linked to Breast Implants (HealthSCOUT)
    ...although there`s no link to breast cancer, the implants may be connected to lung or brain cancer, leading those opposed to surgical enhancement to say this is a warning signal to women everywhere.......In addition, 11 cases of brain tumors among the implant patients were identified on death certificates....
    - Apr 27 3:02 AM ET


  1555. [04/26/2001] Light Therapy Tested for Brain Tumors (Reuters)
    Brain tumors may be the next target for photodynamic therapy (PDT), which combines drugs and light to treat cancer and other conditions.
    - Apr 26 1:56 PM ET


  1556. [04/23/2001] Spacesuit Protects Boy From Sun (Associated Press)
    ...When Cardi was 14 months old, he had two brain tumors removed....
    - Apr 23 6:08 PM ET


  1557. [04/23/2001] Bio-logic Systems Corp. Signs Agreements With Novation, The Largest Supply Cost Management Company in Health Care (PR Newswire)
    ...The systems conduct tests that are typically used by medical practitioners to aid in the diagnosis of certain brain disorders and tumors, neurological and sensory disorders,...
    - Apr 23 6:56 PM ET


  1558. [04/21/2001] Lawsuits Target Cellphone Industry on Hazards (Reuters)
    The U.S. cellular telephone industry came under renewed legal attack this week, in a series of class-action lawsuits claiming that cell phones pose a series of health risks ranging from infections to brain damage.
    - Apr 21 2:35 PM ET


  1559. [04/19/2001] American Shared Hospital Services Appoints Vice President-Sales (Business Wire)
    ...The Gamma Knife treats certain vascular malformations and brain tumors without invasive surgery....
    - Apr 19 5:00 AM ET


  1560. [04/17/2001] American Shared Hospital Services Announces Annual Meeting Date (Business Wire)
    ...The Gamma Knife treats certain vascular malformations and brain tumors without invasive surgery....
    - Apr 17 1:00 PM ET


  1561. [04/18/2001] American Shared Hospital Services Reports 33% Increase in First Quarter 2001 Core Operating Earnings and Announces Earnings Call (Business Wire)
    ...These results support our belief that Gamma Knife technology is the best radiation therapy treatment for brain cancer.......The Gamma Knife treats certain vascular malformations and brain tumors without invasive surgery....
    - Apr 18 5:00 AM ET


  1562. [04/17/2001] Compound Shrinks Brain Tumors in Mice (Reuters)
    An experimental compound appears promising as a treatment for an incurable form of brain cancer, according to a study in animals. In experiments in mice, treatment with the drug stopped tumors from growing in some animals and shrank tumors in others.
    - Apr 17 2:21 PM ET


  1563. [04/17/2001] Introgen and Collaborators at M. D. Anderson Cancer Center Demonstrate Systemic Delivery With Improved Non-Viral System (PR Newswire)
    ...``Successful Treatment of Primary and Disseminated Human Lung Cancers by Systemic Delivery of Tumor Suppressor Genes Using an Improved Liposome Vector`` conducted at the M. D. Anderson Cancer Center,......Liposomal complexes of the tumor suppressor genes were tested for their ability to induce anti-tumor effects when administered intratumorally by injection into primary tumors, and by intravenous injection into models of metatstatic disease.......Introgen is also conducting a Phase II clinical trial for INGN 201 in lung cancer and Phase I trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer....
    - Apr 17 7:30 AM ET


  1564. [04/12/2001] ASNR Meeting Brings Diverse Health Issues Into Focus: A Sharper Image of Stroke, Alzheimers, Brain Tumors, Back-Pain Treatment, The Pediatric Brain (PR Newswire)
    ...Dr. Mitchel Berger will speak on the use of radiological imaging to guide surgeons during brain-tumor surgery....
    - Apr 12 2:00 PM ET


  1565. [04/13/2001] Rochester Area Jaycees Announce Benefit To Save 13-year Old From Brain Disorder (PR Newswire)
    ...Tyson is a 13-year old boy who has undergone over 100 surgeries on his brain and spine to correct a condition called Psuedo Tumor Cerebri....
    - Apr 13 11:07 AM ET


  1566. [04/10/2001] Pharmacyclics Announces Start of Xcytrin Phase II Clinical Trial in Primary Brain Tumors (PR Newswire)
    Pharmacyclics, Inc. today announced the initiation of a Phase II clinical trial to evaluate the company`s investigational lead product, Xcytrin(R) Injection, for treatment of glioblastoma multiforme, the most common primary central nervous system tumor in adults.
    - Apr 10 7:30 AM ET


  1567. [04/06/2001] Neurosurgery Study Identifies Breakthrough for Brain Surgery (Business Wire)
    The latest advance in intraoperative MRI technology is revolutionizing brain surgery according to the lead article in the April 2001 issue of Neurosurgery. Study data from 20 patient cases shows that a new generation of compact intraoperative imaging with integrated navigation enables the neurosurgeon to operate more accurately and confidently.
    - Apr 06 7:02 AM ET


  1568. [04/05/2001] Sagemark Companies Enters Medical Imaging Field (Business Wire)
    ...~~~PET scanning is a revolutionary medical diagnostic imaging technology that allows physicians to pinpoint and accurately diagnose life threatening cancers as well as a variety of brain disorders, including Alzheimer`s Disease and a variety of seizure disorders including epilepsy.......PET provides physicians with important early detection information about such diseases and is the most accurate non-invasive procedure currently available to determine whether or not a tumor is malignant or benign....
    - Apr 05 10:32 AM ET


  1569. [04/03/2001] Brain Surgeons To Use Improved MRI (Cleveland - NewsNet5)
    Brain surgeons at the Cleveland Clinic are among the first in the nation to use a new MRI during surgery.
    - Apr 03 5:22 PM ET


  1570. [04/02/2001] Microvision Signs Clinical Partner (PR Newswire)
    ...``inside the body`` view during such procedures as catheter stent placement, radiation treatment of prostate tumors, brain surgery and anesthesiology monitoring....
    - Apr 02 6:00 AM ET


  1571. [03/29/2001] Drug Eases Depression from Cancer Therapy (HealthSCOUT)
    ...Unlike other skin tumors, which tend to expand across skin, melanoma has a nasty propensity to burrow deep into the tissue until it reaches lymph glands and blood,......the point at which the disease has seeded lymph tissue, but not yet taken up residence in the brain, liver or other organs....
    - Mar 29 3:05 AM ET


  1572. [03/29/2001] Reducing The Risks During Brain Surgery (Internet Wire)
    **VIDEO AVAILABLE** Each year more than 100,000 people are diagnosed with brain tumors. But what they probably don`t know is that to the naked eye, healthy brain tissue and cancerous tissue can look almost identical.
    - Mar 29 9:00 AM ET


  1573. [03/29/2001] Introgen Preclinical Studies Indicate Therapeutic Potential of INGN 241 In Lung Cancer (PR Newswire)
    ...``The ability of the mda-7 gene to suppress the growth of lung tumors in a preclinical setting had not been shown before,......``These studies have demonstrated that INGN 241 may have both anti-tumor and anti-angiogenic activities.......Introgen is also conducting a Phase II clinical trial for INGN 201 in lung cancer and Phase I trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain and breast cancer....
    - Mar 29 7:30 AM ET


  1574. [03/28/2001] Stanford to Test Transplanted Nerve Cells to Treat Stroke Patients (Business Wire)
    Human cells coaxed in the laboratory to become neurons soon will be implanted into the brains of stroke patients at Stanford University Medical Center. Neurosurgeons and neurologists hope the new neurons will be able to pinch-hit for their stroke-damaged counterparts and relieve the long-term weakness and loss of motor control suffered by many stroke victims.
    - Mar 28 7:30 PM ET


  1575. [03/29/2001] Odin Medical Technologies` PoleStar N-10 For Intraoperative MR Imaging Sets A New Standard in Neurosurgery (Business Wire)
    A breakthrough in magnetic resonance imaging technology is giving neurosurgeons new vision. Until recently, doctors were only able to use MRI scans as a diagnostic tool to obtain images of brain tumors before and after surgery.
    - Mar 29 5:05 AM ET


  1576. [03/29/2001] Reducing The Risks During Brain Surgery (Internet Wire)
    **VIDEO TO BE AVAILABLE** Each year more than 100,000 people are diagnosed with brain tumors. But what they probably don`t know is that to the naked eye, healthy brain tissue and cancerous tissue can look almost identical.
    - Mar 29 9:00 AM ET


  1577. [03/28/2001] Child`s Cancer Therapy Can Lead to Tumors Later On (Reuters)
    ...The most common secondary tumor was breast cancer, found in 60 women.......Forty-three people had thyroid tumors and 36 had brain tumors....
    - Mar 28 10:27 AM ET


  1578. [03/25/2001] A High-Tech Test for the Vocal Cords (HealthSCOUT)
    ...-- normally used to detect problems such as brain tumors -...
    - Mar 25 12:32 PM ET


  1579. [03/25/2001] WHO TO SEE FOR STAR TREATMENT (New York Post)
    ...Weill Cornell Medical Center; 212-746-6141 Jerome Posner Neuro-oncology and brain tumors; Memorial Sloan Kettering; 212-639-7047 Michael Swerdlow Myasthenia gravis;...
    - Mar 25 2:39 AM ET


  1580. [03/21/2001] Good Progress in Phase 1 Study of MediGene`s Novel Anticancer Therapeutic NV1020 to Treat Colorectal Cancer Metastatic to the Liver (PR Newswire)
    ...This combination of properties makes NV1020 ideally suited as a unique anti-tumor therapeutic.......MediGene recently announced that its other modified HSV-1 anticancer candidate, G207, for treatment of brain tumors, has successfully completed phase 1 clinical trials and is about to enter further clinical development....
    - Mar 21 8:31 AM ET


  1581. [03/20/2001] Chicago Institute for Neurosurgery and Neuroresearch Launches Nation`s First Comprehensive Neurosurgical Spine Care Center (Business Wire)
    ...CINN is one of the nation`s leading organizations for the diagnosis, treatment and rehabilitation of people with brain and spine disorders.......CINN treats more patients with brain tumors and spine disorders than any other health provider in Illinois....
    - Mar 20 9:01 AM ET


  1582. [03/16/2001] Children`s National Medical Center Launches $250 Million Fund Raising Campaign By Announcing More Than $155 Million in Major Gifts Already Received (PR Newswire)
    ...-- The Center for Neuroscience and Behavioral Medicine - to develop new neuroimaging techniques and epilepsy treatments, and unravel the mysteries of brain development.......including caring for one-tenth of the nation`s children afflicted with pediatric brain tumors....
    - Mar 16 12:00 PM ET


  1583. [03/14/2001] Brain Cancer Patients Get Hope From Pill (KITV TheHawaiiChannel.com)
    According to the Brain Tumor Society, more than 100,000 Americans will be diagnosed with a brain tumor over the next year. In children and young adults, brain tumors are the second leading cause of cancer death. The cause is unknown, but certain factors can increase its risk, such as exposure to radiation or having an impaired immune system. In rare cases, brain tumors run in families.
    - Mar 14 10:22 PM ET


  1584. [03/16/2001] Microscopes Help Doctors With Tricky Brain Surgery (WYFF TheCarolinaChannel.com)
    You have a brain tumor; it`s one of the scariest phrases you can hear out of a doctor`s mouth.
    - Mar 16 9:39 AM ET


  1585. [03/13/2001] Fairview-University Brain Tumor Center Holds Symposium (PR Newswire)
    The Fairview-University Brain Tumor Center will hold its second annual Upper Midwest Brain Tumor Symposium March 23 and 24 at the Radisson Hotel South in Bloomington, Minn.
    - Mar 13 10:10 AM ET


  1586. [03/10/2001] Obituaries in the News (Associated Press)
    ...a former North Dakota House Democratic floor leader who served seven years as U.S. attorney, died Friday of brain cancer....... three months after undergoing surgery for a brain tumor.PHILADELPHIA (AP) - Dr. Sidney Weinhouse, a biochemist who pioneered advances in cancer research,...
    - Mar 10 7:22 AM ET


  1587. [03/06/2001] Obituaries in the News (Associated Press)
    ...a champion of Chicago-area original theater, died Sunday of a brain tumor....
    - Mar 06 6:26 AM ET


  1588. [03/06/2001] Positive Phase 1 Data - Phase 2 Trial For MediGene`s Novel Anticancer Therapeutic Being Prepared (PR Newswire)
    The biopharmaceutical company MediGene AG announced today that its wholly owned subsidiary MediGene, Inc. based in San Diego, USA, has submitted a final study report of its phase 1 clinical trial for G207, a novel anticancer therapeutic for the treatment of brain tumors to the FDA, the US American Food and Drug Administration.
    - Mar 06 7:03 AM ET


  1589. [03/01/2001] Looking Sideways and Hearing Bells (HealthSCOUT News)
    Changes in the brain`s ability to prioritize perceptions may cause some forms of ringing in the ears, new research shows.
    - Mar 01 3:04 AM ET


  1590. [02/26/2001] Study: Ringing in Ears Could Be Linked to Eyes (Reuters)
    ... - The annoying ringing in the ears that marks tinnitus could be linked to the eyes as well as to the ears, researchers said on Monday.A part of the brain associated with vision may be involved in tinnitus,......in which the loudness and pitch of this buzzing increase when a patient looks to the side.GET sometimes develops after surgery to remove tumors of the auditory nerve....
    - Feb 26 4:40 PM ET


  1591. [02/24/2001] For Courage, These Survivors Honored (HealthSCOUT News)
    ...They include: Mary Coffin: a teen-ager with inoperable brain cancer, who on her own has raised more than $15,000 for cancer research Diane Nero-......yet still volunteers to help other patients JoAnn Concannon: a 57-year-old who was diagnosed with ovarian cancer at age 24 and endured a decade of surgeries to remove cancerous tumors....
    - Feb 24 12:36 PM ET


  1592. [02/21/2001] American Shared Hospital Services Declares Annual Dividend (Business Wire)
    ...The Gamma Knife treats certain brain tumors, vascular malformations and Trigeminal Neuralgia (facial pain) without invasive surgery....
    - Feb 21 1:06 PM ET


  1593. [02/14/2001] Drug hunts down and bursts cancer cells (Detroit Free Press)
    For eight hours, while doctors performed sophisticated surgery on his brain, a 34-year-old Dearborn Heights man lay awake so he could respond to doctors` questions.
    - Feb 14 6:00 AM ET


  1594. [02/12/2001] Man Says That Prayer Helps Him Heal (KOCO)
    ...~~~It`s not every day that you hear the words, `We think you have a malignant tumor,` so that hit me pretty hard,~~~ he said.......That news came after an MRI revealed a large mass on the right side of his brain....
    - Feb 12 10:15 PM ET


  1595. [02/07/2001] Medtronic Introduces StealthStation(R) TREON(TM) System, Further Reducing Guesswork in High-Risk Surgery (PR Newswire)
    Achieving another milestone in the accuracy and precision of surgery on the brain, spine and other anatomical systems, Medtronic, Inc., today announced commercial launch of the Medtronic StealthStation(R) TREON(TM) Treatment Guidance System.
    - Feb 07 1:21 PM ET


  1596. [02/06/2001] New Therapy Offers Hope for Brain Cancer Patients (Reuters)
    A new treatment that teaches a patient`s immune cells to recognize cancer cells offers hope for longer survival with a deadly brain cancer called glioblastoma.
    - Feb 06 5:55 PM ET


  1597. [01/24/2001] United Way Honors Man For Courage (WCVB)
    A Randolph man was being honored for his courage on Wednesday after enduring a number of surgeries after doctors discovered that he had a brain tumor.
    - Jan 24 7:01 PM ET


  1598. [01/24/2001] Introgen Awarded Grant From National Cancer Institute to Evaluate INGN 241 In Lung Cancer (PR Newswire)
    ..., a novel gene-based drug for the induction of apoptosis (programmed cell death) in various tumor types.......This ongoing study examines the use of the drug in cancer patients with solid tumors such as breast cancer.......Introgen is also conducting a Phase II clinical trial for INGN 201 in lung cancer and Phase I trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer....
    - Jan 24 7:31 AM ET


  1599. [01/22/2001] American Shared Hospital Services Announces Fourth Quarter and Year End 2000 Financial Results and Schedules Earnings Conference Call (Business Wire)
    ...``Our continued same center growth demonstrates increased acceptance of the Gamma Knife as an alternative to conventional neurosurgery, particularly for metastatic brain tumors and trigeminal neuralgia....
    - Jan 22 4:59 AM ET


  1600. [01/22/2001] American Shared Hospital Services Announces Fourth Quarter and Year End 2000 Financial Results and Schedules Earnings Conference Call (Business Wire)
    ...``Our continued same center growth demonstrates increased acceptance of the Gamma Knife as an alternative to conventional neurosurgery, particularly for metastatic brain tumors and trigeminal neuralgia....
    - Jan 22 4:59 AM ET


  1601. [01/19/2001] Nucletron Announces First Clinical Use of New IMRT Procedure By Physicians at The Children`s Hospital, Los Angeles (PR Newswire)
    ...A five-year old girl underwent the new therapy for a pelvic germ cell tumor that has recurred three times, most recently in September.......At Children`s Hospital Los Angeles, we have compared treatment plans made with ITP to the best conformal plans we were able to design for our patients with brain, abdominal, and pelvic tumors....
    - Jan 19 1:11 PM ET


  1602. [01/11/2001] Bucknell football coach Gadd undergoes brain surgery (SportsTicker)
    Bucknell football coach Tom Gadd underwent successful surgery Thursday to remove a small tumor from the surface of his brain, the school announced.
    - Jan 11 1:37 PM ET


  1603. [01/11/2001] Bucknell Football Coach Undergoes Brain Surgery (Reuters)
    Bucknell football coach Tom Gadd underwent successful surgery Thursday to remove a small tumor from the surface of his brain, the school announced.
    - Jan 11 1:52 PM ET


  1604. [01/11/2001] Integra NeuroSciences and GMSmbH Announce FDA Clearance for LICOX Brain Tissue Oxygen Monitoring System (Business Wire)
    Integra LifeSciences Holdings Corporation and GMSmbH today announced that Integra NeuroSciences has received 510(k) clearance from the United States Food and Drug Administration to market the LICOX(R) Brain Tissue Oxygen Monitoring System in the United States.
    - Jan 11 8:51 AM ET


  1605. [01/10/2001] With its champion`s heart, Nike could help fight brain tumors The tumors are debilitating and deadly, and the way to battle them is to dedicate resources to finding a cure

  1606. [01/10/2001] Low-Cost Brain Scans A Click Away (KCRA)
    Federal health authorities recently did brain scans on 1,000 normal, healthy volunteers. Three of those volunteers had undetected brain tumors.
    - Jan 10 2:00 PM ET


  1607. [01/10/2001] ``Smart Probe`` for Breast Cancer Detects Malignant Tumors Instantly (Business Wire)
    The pain and anxiety women experience undergoing breast cancer tests and awaiting the results may soon be lessened thanks to a new, minimally invasive diagnostic tool that can instantly detect cancerous tissue.
    - Jan 10 12:12 PM ET


  1608. [01/09/2001] High School Goalie Battles Brain Tumor (WCCO)
    Major Bowen faces heavy slap shots as a goalie for the Blake High School hockey team, but the 17-year-old now faces a more difficult challenge.
    - Jan 09 7:01 PM ET


  1609. [01/09/2001] Maureen Reagan Undergoing Cancer Treatment (PR Newswire)
    Maureen Reagan, the daughter of former President Ronald Reagan and actress Jane Wyman, is undergoing a highly aggressive treatment at the John Wayne Cancer Institute at Saint John`s Health Center in Santa Monica, California, for malignant melanoma, the deadliest form of skin cancer.
    - Jan 09 5:00 AM ET


  1610. [01/08/2001] Obituaries in the News (Associated Press)
    Sigge Bergman, a top executive with skiing`s governing body for more than 30 years, died Saturday in Rattvik, the Swedish news agency TT said. He was 95.
    - Jan 08 6:01 AM ET


  1611. [01/05/2001] N.Y. Brain surgeon Cleared (Associated Press)
    A neurosurgeon twice accused of operating on the wrong side of patients` brains has been cleared and had his license restored.
    - Jan 05 7:07 AM ET


  1612. [01/05/2001] N.Y. Brain Surgeon Cleared (Associated Press)
    A neurosurgeon twice accused of operating on the wrong side of patients` brains has been cleared and had his license restored.
    - Jan 05 9:00 AM ET


  1613. [01/04/2001] Innovative Brain Surgery Gives Patients Hope For The Future (Houston - KPRC)
    The idea of being awake and lucid while doctors remove a tumor from the brain may amaze some and worry others, but a new life-saving procedure is giving hope to people suffering from brain cancer.
    - Jan 04 6:00 PM ET


  1614. [01/04/2001] MAMSI Children`s Foundation, Inc. Awards Grants to Four Children (Business Wire)
    MAMSI Children`s Foundation, Inc. announced today that it recently awarded grants to four children from Maryland, Pennsylvania and Virginia who are in need of medical services that are not covered by their insurance.
    - Jan 04 1:34 PM ET


  1615. [01/04/2001] U.S. Neurosurgical, Inc. Announces Stock Repurchase Program (PR Newswire)
    U.S. Neurosurgical, Inc. announced that its Board of Directors has approved a stock repurchase program for up to 500,000 shares of the Company`s common stock.
    - Jan 04 11:11 AM ET


  1616. [12/25/2000] Christmas Cheer Spreads Across U.S. (Associated Press)
    For Peter Deng and Clement Garang, Christmas this year had an extra special element: snow.
    - Dec 25 9:24 PM ET


  1617. [12/25/2000] Christmas Cheer Spreads Across U.S. (Associated Press)
    For Peter Deng and Clement Garang, Christmas this year had an extra special element: snow.
    - Dec 25 6:20 PM ET


  1618. [12/24/2000] Teen recovering well from brain tumor surgery (Daily Herald)
    Before a recent surgery, Patty Hall would ask her son, Mike, to rate the pain of his headaches on a scale of one to 10.
    - Dec 24 7:58 AM ET


  1619. [12/24/2000] UA fans need patience until Woods steps up (The Arizona Daily Star)
    Sunday`s short stuff: No one has become more popular to knock that Loren Woods. He`s too soft, his critics say. He can`t dunk. He`s not a rebounder. He`s passive. He`s not this. He`s not that.
    - Dec 24 1:26 AM ET


  1620. [12/22/2000] Louisiana-Lafayette assistant McQuillin dies from brain tumor (SportsTicker)
    Louisiana-Lafayette defensive ends coach Mark McQuillan, who collapsed prior to the Ragin` Cajuns` game against Louisiana-Monroe on November 4, died this morning at Our Lady of Lourdes Medical Center. He was 38.
    - Dec 22 5:00 PM ET


  1621. [12/21/2000] NewsRx: Internet Health Information Provides Booster Shot for World (PR Newswire)
    Health information from the Internet is the key ingredient for advancing world health, according to a health publishing executive.
    - Dec 21 8:02 AM ET


  1622. [12/21/2000] Fast-tracking Cancer Treatments (HealthSCOUT News)
    Cancer treatment is tough enough without having to wait months to find out whether it`s working.
    - Dec 21 3:53 AM ET


  1623. [12/16/2000] More bad news for Drake: freshman has brain tumor (AP)
    Four days after learning that a teammate has Hodgkin`s disease, the Drake women`s basketball team found out Saturday that another teammate has a brain tumor.
    - Dec 16 9:16 PM ET


  1624. [12/16/2000] Drake`s Kappel Has Brain Tumor (Associated Press)
    Four days after learning that a teammate has Hodgkin`s disease, the Drake women`s basketball team found out Saturday that another teammate has a brain tumor.
    - Dec 16 9:22 PM ET


  1625. [12/07/2000] Introgen Presents Preclinical Results of Gene-Based Anti-Angiogenesis Therapy (PR Newswire)
    Introgen Therapeutics, Inc. today reported preclinical results for its gene-based anti-angiogenesis therapy, INGN 241, an Adenoviral-mda7 product candidate, currently in Phase I clinical testing.
    - Dec 07 4:29 PM ET


  1626. [12/07/2000] Conemaugh Health System Announces Plans for a Regional Cancer Network (PR Newswire)
    Conemaugh Health System today announced plans for a Regional Cancer Network to include a new state-of-the-art cancer center to serve the residents of West Central Pennsylvania.
    - Dec 07 1:27 PM ET


  1627. [12/07/2000] American Shared Hospital Services Announces Open House for Its Gamma Knife Unit At Sunrise Hospital and Medical Center and Children`s Hospital At Sunrise (Business Wire)
    AMERICAN SHARED HOSPITAL SERVICES, the world leader in providing Gamma Knife radiosurgery services, Thursday announced that an Open House was held yesterday at its tenth Gamma Knife unit located at Sunrise Hospital and Medical Center and Children`s Hospital at Sunrise in Las Vegas, Nevada.
    - Dec 07 2:03 PM ET


  1628. [12/01/2000] Jefferson Creates Hospital for Neuroscience (PR Newswire)
    The new Jefferson Hospital for Neuroscience will consolidate one of the nation`s busiest neurosurgery programs in what is now the Wills Eye Hospital building, creating an additional site for Thomas Jefferson University Hospital, Philadelphia.
    - Dec 01 10:19 AM ET


  1629. [11/30/2000] Peregrine Pharmaceuticals Announces the Treatment of the First Patient in the Stanford University Cotara Clinical Trial (Business Wire)
    Peregrine Pharmaceuticals Inc., today announced that the first patient has been enrolled and treated in the new Phase I clinical study for colorectal cancer being conducted at Stanford University Medical School using Peregrine`s Cotara(TM) drug which is also being used in a Phase II clinical trial for the treatment of brain cancer.
    - Nov 30 7:33 AM ET


  1630. [11/29/2000] Allos Therapeutics, Inc. Announces Positive Phase II Response Rate Data of RSR13 for Treatment of Non-Small Cell Lung Cancer (PR Newswire)
    Allos Therapeutics, Inc. announced today positive preliminary response rate data for treatment of patients with locally advanced, inoperable non-small cell lung cancer. The results come from an open-label, multi-center, Phase II clinical trial of induction chemotherapy followed by radiation therapy in combination with RSR13 for Stage IIIA and IIIB NSCLC.
    - Nov 29 8:02 AM ET


  1631. [11/28/2000] Integrated Surgical Systems Announces It Has Received an Order for Six NeuroMate(TM) Surgical Systems from Japan (PR Newswire)
    Integrated Surgical Systems, Inc., a pioneer in medical robotics and the world leader in image-directed, semi-autonomous robotic products for surgical applications, announced today that it has received an order for six NeuroMate(TM) Surgical Systems from Imatron-Japan, it`s Japanese distributor.
    - Nov 28 9:04 AM ET


  1632. [11/28/2000] Integrated Surgical Systems Announces It Has Received an Order for Six NeuroMate(TM) Surgical Systems from Japan (PR Newswire)
    Integrated Surgical Systems, Inc., a pioneer in medical robotics and the world leader in image-directed, semi-autonomous robotic products for surgical applications, announced today that it has received an order for six NeuroMate(TM) Surgical Systems from Imatron-Japan, it`s Japanese distributor.
    - Nov 28 9:04 AM ET


  1633. [11/21/2000] VHLFA: They Have Come a Long Way, Baby! (PR Newswire)
    She was told in 1964, she was one of a handful of people diagnosed with the rare disease von-Hippel Lindau. Celebrating with family and friends, in July, her 70th birthday, Neatha D. has beaten the odds and lived twice the expected age, predicted in the 1960`s, for persons with this hereditary cancer.
    - Nov 21 11:02 AM ET


  1634. [11/13/2000] Onyx Reports Progress with Diverse Portfolio of Novel, Targeted Anticancer Therapeutics (PR Newswire)
    Onyx Pharmaceuticals, Inc. announced today that new clinical and preclinical data demonstrating the breadth of the company`s promising approaches to treating cancer were presented at the 11th Annual NCI-EORTC-AACR Symposium on New Drugs in Cancer Therapy, held last week in Amsterdam, Netherlands.
    - Nov 13 6:31 AM ET


  1635. [11/09/2000] Guilford Announces Phase III Clinical Trial Results for Gliadel(R) Wafer in First-Line Treatment of Malignant Glioma (PR Newswire)
    Guilford Pharmaceuticals Inc. announced today that GLIADEL(R) Wafer prolonged survival and improved neurological outcomes in patients who were enrolled in a Phase III clinical trial to investigate the treatment benefit of GLIADEL(R) Wafer when used at the time of initial surgery for the treatment of malignant glioma.
    - Nov 09 8:19 AM ET


  1636. [11/09/2000] Gene Foretells Whether Chemo Works (HealthSCOUT News)
    Researchers have detected a genetic twist that determines whether patients with one kind of brain cancer will be helped by chemotherapy -- a finding that could eventually be applied to help improve treatment of a broad range of common cancers.
    - Nov 09 3:05 AM ET


  1637. [11/08/2000] Integra LifeSciences Reports $1.7 Million Net Income on 61% Growth in Revenues (Business Wire)
    Integra LifeSciences Holdings Corporation today reported financial results for the third quarter ended September 30, 2000. Revenues for the quarter were $19.6 million, an increase of approximately $7.4 million, or 61 percent, from revenues of $12.1 million for the comparable quarter ended September 30, 1999.
    - Nov 08 7:10 AM ET


  1638. [11/07/2000] Sun Microsystems Leverages the Network to Enable Massive Scalability in High Performance Computing (PR Newswire)
    As an established leader in High Performance Computing and network technology, Sun Microsystems, Inc. is helping HPC customers capitalize on the Net Effect -- the trend driving the exponential growth and increasing opportunities of the Internet as users, devices, services, data and demand for high availability continue to multiply.
    - Nov 07 7:01 AM ET


  1639. [11/04/2000] Better Way Found to Get Inside Your Head (HealthSCOUT News)
    A new system that uses magnets and advanced computer imaging allows surgeons to precisely direct a flexible catheter along a curved path within the brain or other parts of the body.
    - Nov 04 12:35 PM ET


  1640. [11/04/2000] Brain Tumor Awareness Day (HealthSCOUT News)
    Someone dies of a brain tumor every 20 minutes in the United States, and 100,000 Americans will find out they have a brain tumor this year.
    - Nov 04 12:35 PM ET


  1641. [11/03/2000] Could Your Cell Phone Be Dangerous? (Houston - KPRC)
    More and more people are becoming dependent on their cell phones, but there may be new evidence that the gadgets may pose possible dangers.
    - Nov 03 9:01 AM ET


  1642. [11/02/2000] MDX Medical Establishes New Facilities (CCN Disclosure)
    VANCOUVER, BRITISH COLUMBIA--The Company is pleased to announce that MDX Medical has moved into new facilities in the Jack Bell Research Centre of Vancouver General Hospital where the Company`s initial technologies are being advanced. The MDX facilities have been outfitted with essential electronics and other lab and computer equipment to service current and future medical device project work. MDX will also have full access to the Jack Bell machine shop which is equipped to support prototype construction....
    - Nov 02 1:07 PM ET


  1643. [11/02/2000] Neurocrine Biosciences Reports Third Quarter 2000 Results (Business Wire)
    Neurocrine Biosciences Inc. today announced its financial results for the third quarter ended September 30, 2000.
    - Nov 02 7:33 AM ET


  1644. [11/01/2000] Using Ultrasound To Battle Cancer (Associated Press)
    Vicki Freeman lay perfectly still inside a tube-like machine as ultrasound waves beamed deep into her cancerous breast. Little bursts of heat signaled the beams were cooking her tumor to death - without a mark or cut to her skin.
    - Nov 01 11:32 AM ET


  1645. [10/31/2000] Promise Ring Quit Bad Religion Tour (SonicNet)
    Emo-rock outfit the Promise Ring have cut short their tour with veteran punks Bad Religion, citing health issues related to singer/guitarist Davey vonBohlen`s recent battle with a brain tumor.
    - Oct 31 6:45 PM ET


  1646. [10/30/2000] Using Ultrasound to Battle Cancer (Associated Press)
    Vicki Freeman lay perfectly still inside a tube-like machine as ultrasound waves beamed deep into her cancerous breast. Little bursts of heat signaled the beams were cooking her tumor to death - without a mark or cut to her skin.
    - Oct 30 5:00 PM ET


  1647. [10/26/2000] Micro Therapeutics Reports 2000 Third Quarter Financial Results (Business Wire)
    --
    - Oct 26 8:20 AM ET


  1648. [10/25/2000] Brain Tumor Awareness Day - The Heart of the Matter; November 12 Conference to Share Knowledge, Information, Experiences with Compassion and Care (PR Newswire)
    For a few short hours on Sunday, November 12, 2000, hundreds of medical experts, patients, survivors and family members from across the country and around the world will gather here to discuss a subject they know all too well: Brain Tumors.
    - Oct 25 4:19 PM ET


  1649. [10/25/2000] Allos Therapeutics, Inc. Announces Extended Survival Data of RSR13 For Primary and Metastatic Brain Cancers at the American Society Of Therapeutic Radiation & Oncology (PR Newswire)
    Allos Therapeutics, Inc. announced today positive, extended survival data of two Phase II clinical trials of RSR13 combined with cranial radiation therapy in patients with glioblastoma multiforme and patients with brain metastases.
    - Oct 25 11:36 AM ET


  1650. [10/25/2000] Auditory Brainstem Implant Approved By FDA: House Ear Institute Sees Fruits of Scientific Effort After 21 Years (PR Newswire)
    It began with one patient in 1979. Two physicians affiliated with the House Ear Clinic, William House, M.D., and William Hitselberger, M.D., were the first to implant a pair of electrodes in the brainstem of a Neurofibromatosis Type II patient during surgery to remove acoustic tumors.
    - Oct 25 8:17 AM ET


  1651. [10/24/2000] FDA Okays Brainstem Implant for Deafness (Reuters)
    The US Food and Drug Administration (FDA) approved a device on Monday that is implanted into the brainstem to combat tumor-related hearing loss.
    - Oct 24 1:36 PM ET


  1652. [10/24/2000] Guilford Reacquires Commercial Rights to GLIADEL(R) Wafer - First Localized Treatment for Malignant Brain Cancer (PR Newswire)
    Guilford Pharmaceuticals Inc., developer of GLIADEL(R) Wafer, the first significant new treatment for malignant brain cancer in over 20 years, today announced that it has reacquired commercial rights to its flagship biopolymer product, GLIADEL(R) Wafer, from Aventis Pharma, the pharmaceutical company of Aventis S.A..
    - Oct 24 8:07 AM ET


  1653. [10/23/2000] FDA Approves Implanted Hearing Device (Reuters)
    U.S. health officials announced on Monday they had approved a device that gives some people with a rare type of hearing loss the ability to detect some sounds and speech.
    - Oct 23 5:44 PM ET


  1654. [10/23/2000] Proxima Therapeutics Files for 510(k) Clearance for GliaSite(R) Radiation Therapy System for Treatment of Brain Tumors (PR Newswire)
    Proxima Therapeutics Inc., a developer and marketer of site-specific cancer treatments, today announced that it has filed with the United States Food and Drug Administration for 510(k) clearance to market its GliaSite RTS treatment for brain tumors.
    - Oct 23 11:21 AM ET


  1655. [10/19/2000] American Shared Hospital Services Reports Third Quarter 2000 Financial Results and Schedules Conference Call (Business Wire)
    American Shared Hospital Services(PCX:AMS), the world leader in providing Gamma Knife radiosurgery services, Thursday announced financial results for the three months and nine months ended September 30, 2000.
    - Oct 19 5:01 AM ET


  1656. [10/13/2000] Congressman Bruce Vento`s Cause of Death Clarified (PR Newswire)
    Bruce Vento, a popular, 23 year Congressman from Minnesota, died Tuesday from what the press widely reported as ~~~lung cancer.~~~
    - Oct 13 8:20 PM ET


  1657. [10/13/2000] Congressman Bruce Vento`s Cause of Death Clarified (PR Newswire)
    Bruce Vento, a popular, 23 year Congressman from Minnesota, died Tuesday from what the press widely reported as ~~~lung cancer.~~~
    - Oct 13 6:01 PM ET


  1658. [10/12/2000] American Shared Hospital Services Schedules Conference Call About Third Quarter 2000 Earnings (Business Wire)
    American Shared Hospital Services will host a telephone conference call on Thursday, October 19, 2000 at 3:00 p.m. Eastern time. American Shared is the world leader in providing Gamma Knife radiosurgery services.
    - Oct 12 5:00 AM ET


  1659. [10/05/2000] Integra LifeSciences Expects To Exceed Consensus Earnings Estimates of Analysts for Third Quarter (Business Wire)
    Appearing at the UBS Warburg Global Life Sciences Conference, Stuart M. Essig, President and Chief Executive Officer of Integra LifeSciences Holdings Corporation, will announce later today that Integra expects to do better than the $(0.04) per share loss consensus earnings estimates of analysts for the third quarter ended September 30, 2000.
    - Oct 05 8:17 AM ET


  1660. [09/29/2000] Children`s Memorial Hospital, Chicago and Massachusetts General Hospital, Boston, Upgrade to INTRABEAM(TM) System (PR Newswire)
    Photoelectron Corporation, a medical device and technology company specializing in miniature x-ray technology, announced today that the Children`s Memorial Hospital, Chicago and Massachusetts General Hospital have each purchased the counterbalanced, articulated support stand that is the key element of the INTRABEAM(TM) system.
    - Sep 29 8:59 AM ET


  1661. [09/22/2000] AS&E Announces $3.5 Million Award from Accuray Oncology (Business Wire)
    American Science and Engineering, Inc. announced today a follow-on order valued at $3.5 million to AS&E(R)`s High Energy Systems division for multiple linear accelerator systems. The accelerators will be manufactured for Accuray Oncology to be used in stereotactic radiosurgery.
    - Sep 22 10:58 AM ET


  1662. [09/14/2000] Biopure to Make Detection Test Available for its Oxygen Therapeutic Drugs (PR Newswire)
    Biopure Corporation today announced that it would make available a proprietary laboratory test that detects the presence of its oxygen therapeutic drugs in human and animal blood.
    - Sep 14 7:30 AM ET


  1663. [09/07/2000] MDX Medical Engages Chief Technology Officer (CCN Disclosure)
    VANCOUVER, BRITISH COLUMBIA--The Company is pleased to announce that Dr. Yunquan Chen has joined MDX in the full time capacity of Chief Technology Officer. Dr Chen, who holds a Ph.D in biomedical engineering, is responsible for leading the Company`s product development as work commences this month at the MDDC Medical Development Centre in facilities of the Vancouver General Hospital, where the Company has leased its initial laboratory space.
    - Sep 07 4:17 PM ET


  1664. [09/07/2000] Pharmacyclics Announces Start of NCI-Sponsored Phase I Clinical Trials Of Xcytrin in Primary Lung Cancer and With Stereotactic Radiosurgery For Advanced Brain Tumors (PR Newswire)
    Pharmacyclics, Inc. today announced the initiation of two Phase I clinical trials with the company`s Xcytrin(R) Injection.
    - Sep 07 7:30 AM ET


  1665. [09/06/2000] Techniclone Reports On Dr. Sunil Patel`s Discussion of Brain Cancer and Cotara on Virtualtrials.com (Business Wire)
    Techniclone Corporation - today reported on Dr. Sunil Patel`s internet chat concerning brain cancer treatments on August 28th. Dr. Patel is an Associate Professor in Neurological Surgery and Director of the Brain Tumor Clinic at the Medical University of South Carolina and is a Principal Investigator for the Techniclone-sponsored clinical trial for Cotara(TM).
    - Sep 06 2:12 PM ET


  1666. [09/06/2000] Biopure Completes Patient Enrollment in Phase III Hemopure(R) Trial (PR Newswire)
    Biopure Corporation today announced it has completed enrolling patients in the pivotal Phase III clinical trial evaluating its investigational oxygen therapeutic drug, Hemopure(R) [hemoglobin glutamer - 250], as a universally compatible alternative to red blood cell transfusion in patients undergoing orthopedic surgery.
    - Sep 06 7:29 AM ET


  1667. [09/06/2000] Integra NeuroSciences and GMSmbH Renew LICOX Distribution Agreement (Business Wire)
    Integra LifeSciences Holdings Corporation today announced that its Integra NeuroSciences division has extended for seven years its exclusive sales and distribution agreement with German manufacturer GMSmbH.
    - Sep 06 8:28 AM ET


  1668. [09/06/2000] Biopure Completes Patient Enrollment in Phase III Hemopure(R) Trial (PR Newswire)
    Biopure Corporation today announced it has completed enrolling patients in the pivotal Phase III clinical trial evaluating its investigational oxygen therapeutic drug, Hemopure(R) [hemoglobin glutamer - 250], as a universally compatible alternative to red blood cell transfusion in patients undergoing orthopedic surgery.
    - Sep 06 7:29 AM ET


  1669. [09/05/2000] Memory Testing Corporation Brings Functional MRI Testing To Regional Hospitals (PR Newswire)
    Neurosurgeons have a dynamic new way to increase quality of patient care and surgical outcome, thanks to an innovative procedure called Functional Magnetic Resonance Imaging. fMRI expands conventional MRI technology by giving doctors a ~~~functional map~~~ of the brain.
    - Sep 05 6:15 AM ET


  1670. [09/04/2000] Popular Mowlam to Quit British Cabinet (Reuters)
    Mo Mowlam, Britain`s popular and outspoken cabinet member, said Monday she will leave parliament at the next election, ending months of speculation over her future.
    - Sep 04 9:08 AM ET


  1671. [08/31/2000] Investigational Treatment for Melanoma, The Most Deadly Skin Cancer, Shows Promise in Clinical Trials (PR Newswire)
    Following the recent announcement that Arizona Senator John McCain has been diagnosed with a recurring melanoma, increased emphasis is placed on potential new treatments for the late stages of the disease.
    - Aug 31 11:50 AM ET


  1672. [08/29/2000] Micro Therapeutics Receives FDA Approval to Advance Aneurysm Feasibility Study to More U.S. Sites (PR Newswire)
    Micro Therapeutics, Inc. has received clearance from the Food and Drug Administration to expand its U.S. aneurysm feasibility study to three sites and 25 patients, announced George Wallace, president and chief executive officer of the Irvine, California-based medical device company.
    - Aug 29 8:02 AM ET


  1673. [08/22/2000] 6-Year-Old Inspires Vancouver Team (Associated Press)
    After surviving surgery to remove a brain tumor in mid-June, 6-year-old Tyler ``TJ`` Jacobs wasn`t about to let anything as minor as a cross-country flight keep him from seeing his favorite team.
    - Aug 22 8:38 PM ET


  1674. [08/23/2000] Davenport Iowa 6, Vancouver, Wash 4 (Associated Press)
    The team from Davenport, Iowa, became the first from the Central Region to reach the U.S. Pool championships at the Little League World Series on Wednesday night, eliminating Vancouver, Wash., which used a 6-year-old boy as their inspiration.
    - Aug 23 10:26 PM ET


  1675. [08/24/2000] Davenport, Bellaire in LLWS (Associated Press)
    Two survivors with much to prove - Davenport, Iowa, and Bellaire, Texas - were left standing for the U.S. championship at the Little League World Series.
    - Aug 24 2:30 AM ET


  1676. [08/24/2000] Study Shows Possible Cancer Link Between Virus and Fiber (PR Newswire)
    For the first time, a possible cancer-causing link has been found between asbestos fibers and a monkey virus that infects some people in the United States, according to the ground- breaking study published as the lead article in the Aug. 31 issue of the Proceedings of the National Academy of Sciences.
    - Aug 24 8:03 AM ET


  1677. [08/24/2000] FMC Chairman/CEO Burt to Resume Full-Time Schedule (PR Newswire)
    FMC Corporation today announced that FMC Chairman and CEO Robert N. Burt will resume his full-time work schedule after Labor Day.
    - Aug 24 4:32 PM ET


  1678. [08/24/2000] Dr. Sunil Patel to Discuss Brain Cancer On Internet Chat Room (Business Wire)
    Techniclone Corporation - today announced that Sunil Patel, M.D., Associate Professor in Neurological Surgery and Director of the Brain Tumor Clinic at the Medical University of South Carolina, will be the featured guest on the Virtual Trials internet chat room on Monday, August 28, 2000, at 7 PM eastern time.
    - Aug 24 9:10 AM ET


  1679. [08/25/2000] Longtime N.Y. PR Executive Dies (Associated Press)
    Philip J. Burke, a longtime New York sports public relations executive with Columbia University, the New York Rangers and the old Roosevelt Raceway has died. He was 65.
    - Aug 25 8:22 PM ET


  1680. [08/02/2000] Allos Therapeutics Completes Patient Enrollment for RSR13 Lung Cancer Study (PR Newswire)
    Allos Therapeutics, Inc. announced today that it has completed patient enrollment in a Phase II clinical trial of its lead drug candidate, RSR13, in patients with non-small cell lung cancer undergoing chemotherapy followed by radiation therapy.
    - Aug 02 9:01 AM ET


  1681. [07/28/2000] New Approach Gives Hope to Brain Tumor Patients; Doctors at Colorado Neurological Institute Treat Patients with Intent to Cure (PR Newswire)
    For most patients, a diagnosis of a malignant brain tumor is like being handed a death sentence. Conventional treatment includes surgery and radiation, and can generally preserve quality of life for six-eighteen months.
    - Jul 28 2:59 PM ET


  1682. [07/26/2000] Pharmos Reports Progress in Dexanabinol Program (PR Newswire)
    Pharmos Corporation presented today the results of its entire Phase II clinical trial for dexanabinol in the treatment of traumatic brain injury at the Eleventh International Symposium on Intracranial Pressure and Brain Monitoring in Cambridge, England.
    - Jul 26 10:19 AM ET


  1683. [07/25/2000] Atlantic Health System to Unveil America`s First Real-Time Radiation Therapy System (PR Newswire)
    The Carol G. Simon Cancer Center at Atlantic Health System`s Morristown Memorial Hospital will unveil the nation`s first CT-on-Rails/Linac System at 4 p.m. Thursday, July 27.
    - Jul 25 1:43 PM ET


  1684. [07/24/2000] Integra NeuroSciences to Distribute ArthroCare`s Coblation-Based Surgical System for Neurosurgery (PR Newswire)
    Integra NeuroSciences, a division of Integra LifeSciences Holdings Corporation, and ArthroCare Corporation today announced an agreement under which Integra will become the exclusive sales and distribution partner for ArthroCare`s Coblation(R)-based surgical system for neurosurgery in North and South America and certain additional international markets.
    - Jul 24 8:03 AM ET


  1685. [07/24/2000] Integra NeuroSciences to Distribute ArthroCare`s Coblation-Based Surgical System for Neurosurgery (Business Wire)
    Integra NeuroSciences, a division of Integra LifeSciences Holdings Corp., and ArthroCare Corp. today announced an agreement under which Integra will become the exclusive sales and distribution partner for ArthroCare`s Coblation(R)-based surgical system for neurosurgery in North and South America and certain additional international markets.
    - Jul 24 8:24 AM ET


  1686. [07/11/2000] NWBio Options Kidney Cancer Technology (PR Newswire)
    Northwest Biotherapeutics, Inc. announced today that it has executed an option to secure an exclusive worldwide license from The Regents of the University of California for a kidney cancer tumor-specific antigen to be used with NWBio`s proprietary dendritic cell-based immunotherapy (~~~DCVax(TM)~~~) for cancer.
    - Jul 11 11:44 AM ET


  1687. [07/02/2000] Doctors Take Aim at Lung Cancer (Associated Press)
    When doctors diagnosed Billy Stamm with lung cancer, there was more bad news to come. Not only was surgery out of the question, the odds weren`t good that he would respond to conventional radiation therapy.
    - Jul 02 12:03 PM ET


  1688. [06/28/2000] FDA Approves Bayer Corporations`s Next Generation Formulation of Recombinant Factor VIII (rFVIII) for Hemophilia A with Added Administration Convenience (PR Newswire)
    The Bayer Corporation announced today that the U.S. Food and Drug Administration approved Kogenate(R) FS Antihemophilic Factor, Formulated with Sucrose [rFVIII FS], a new formulation of recombinant factor VIII for the treatment of hemophilia A that offers more convenient administration.
    - Jun 28 8:25 AM ET


  1689. [06/28/2000] Blind Golfer Out of Special Olympics (Associated Press)
    A legally blind golfer was barred from competing in a state Special Olympics earlier this month because he uses a golf cart to cover long distances.
    - Jun 28 4:04 AM ET


  1690. [06/26/2000] Surgery May Avoid Hysterectomies (Associated Press)
    A Dutch doctor has developed a new method of uterine surgery that early tests indicate is safer and simpler than the current one and could avoid thousands of hysterectomies.
    - Jun 26 4:06 PM ET


  1691. [06/22/2000] Tim Weigel is Released from the Hospital Today and Will Undergo Further Treatment (PR Newswire)
    Tim Weigel, who had surgery to remove a brain tumor on Monday, was released from the Rush-Presbyterian-St. Luke`s Medical Center today, and will undergo further treatment.
    - Jun 22 4:44 PM ET


  1692. [06/20/2000] Monthly News Alert on Technologies Advancing Medicine (Business Wire)
    Cancer rates are declining, according to a study released last month by the National Cancer Institute, the American Cancer Society, the North American Association of Central Cancer Registries and the Centers for Disease Control and Prevention.
    - Jun 20 12:45 PM ET


  1693. [06/20/2000] Atlantic`s Overlook Hospital Performs Angioplasty To Save Heart Attack Patients (PR Newswire)
    Atlantic Health System`s Overlook Hospital is the only community hospital in New Jersey performing life-saving angioplasty on emergency room heart attack victims and has treated 50 patients to date.
    - Jun 20 1:43 PM ET


  1694. [06/19/2000] CBS 2 Chicago`s Tim Weigel is Recovering from Surgery to Remove a Brain Tumor (PR Newswire)
    Tim Weigel, CBS 2 CHICAGO Sports Director since 1995, is recovering after surgery to remove a brain tumor.
    - Jun 19 6:40 PM ET


  1695. [06/19/2000] Brain Tumors Not Always Deadly (PR Newswire)
    You have a brain tumor.~~~ These are some of the scariest words a person can hear.
    - Jun 19 7:40 PM ET


  1696. [06/14/2000] The University of Texas System Awarded Patent for Use of p53 Gene in Combination With DNA Damaging Agents Utilizing Any Type of Delivery System (PR Newswire)
    The Board of Regents of The University of Texas System and Introgen Therapeutics, Inc. announced today that the U.S. Patent and Trademark Office has issued to The Board of Regents of The University of Texas System U.S.
    - Jun 14 1:08 PM ET


  1697. [06/09/2000] Integrated Surgical Systems Announces First Successful U.S. Surgery With NeuroMate(TM) System for Parkinson`s Disease Patient Performed at U.S.C. (PR Newswire)
    Integrated Surgical Systems, Inc., a pioneer in medical robotics and the world leader in image-directed, robotic products for surgical applications in the fields of neurological and orthopedic surgeries, today announced that it performed the first successful U.S. surgery with its NeuroMate(TM) System to treat a Parkinson`s Disease patient.
    - Jun 09 1:00 AM ET


  1698. [06/08/2000] Scientific Medicine Has Many Answers ... Not All (PR Newswire)
    A doctor and patient bring quite different tools to the task of being well says veteran hospital chaplain, Mary Farr. A doctor comes with prescriptions, surgery and a host of medical approaches that cure.
    - Jun 08 5:09 AM ET


  1699. [06/02/2000] Gene Discovered for `Turban Tumor` Condition (Reuters)
    Researchers have discovered the gene that causes ``turban tumors,`` a condition in which people develop multiple round tumors on the hairy areas of their bodies, mostly on the scalp and neck.
    - Jun 02 12:04 PM ET


  1700. [06/01/2000] Investigational Oxygen Therapeutic Sustains Critically Ill Woman Unable to Receive Blood Transfusion (PR Newswire)
    A young woman suffering from a life-threatening form of anemia was stabilized with an investigational oxygen therapeutic drug after standard therapy failed to control her condition, military doctors reported in today`s issue of the New England Journal of Medicine.
    - Jun 01 9:29 AM ET


  1701. [05/24/2000] CI-1042 (ONYX-015) May Have Potential Against Cancer in Variety of Tumor Types (PR Newswire)
    CI-1042 may offer versatility as an anticancer therapeutic, as reported this week by Onyx Pharmaceuticals, Inc. and its collaborators at the annual meeting of the American Society of Clinical Oncology.
    - May 24 6:30 AM ET


  1702. [05/23/2000] Allos Therapeutics, Inc. Announces Improved Survival Achieved With RSR13 Combined With Radiation Therapy in Patients With Glioblastoma Multiforme Brain Cancer, Presented at the American Society of Clinical Oncology Meeting (PR Newswire)
    Allos Therapeutics, Inc. announces positive Phase II survival results with RSR13 combined with cranial radiation therapy in patients with newly diagnosed glioblastoma multiforme brain cancer.
    - May 23 1:30 PM ET


  1703. [05/23/2000] Response Oncology Reports Metastatic Breast Cancer Study Results at the American Society of Clinical Oncology Annual Meeting: (PR Newswire)
    Response Oncology, Inc. today reported the results of a multicenter, phase III metastatic breast cancer study at the 36th Annual Meeting of the American Society of Clinical Oncology.
    - May 23 10:15 AM ET


  1704. [05/21/2000] Vical Reports Progress With Leuvectin in Patients With Kidney Cancer At ASCO (Business Wire)
    Vical Incorporated presented interim data from the company`s Phase II Leuvectin trial for patients with renal cell carcinoma, announced the initiation of a new Phase II Leuvectin kidney cancer trial, and disclosed the award of orphan drug designation by the U.S.
    - May 21 2:01 PM ET


  1705. [05/21/2000] Vical Presents Interim Data From Phase II Allovectin-7 Melanoma Trial At ASCO (Business Wire)
    Dr. M. Atkins, on behalf of the 43 clinical centers working with Vical Incorporated, presented interim safety and efficacy data from the company`s ongoing Phase II Allovectin-7 registration trial for patients with late-stage metastatic melanoma at the annual meeting of the American Society of Clinical Oncology.
    - May 21 2:02 PM ET


  1706. [05/19/2000] Leading Rezulin Attorney Urges FDA to Revamp Drug Reporting Process (PR Newswire)
    Speaking before a U.S. Food and Drug Administration committee today, an attorney spearheading nationwide legal action against pharmaceutical giant Warner-Lambert Co. pleaded with committee members to fix the FDA`s system for reporting dangerous drug side effects and avoid repeating a 1999 decision that kept the diabetes treatment Rezulin on the market another year.
    - May 19 11:59 AM ET


  1707. [05/19/2000] New Data on AstraZeneca Oncology Products to be Presented at the American Society of Clinical Oncology (ASCO) Annual Meeting in New Orleans (PR Newswire)
    New data on several AstraZeneca oncology products will be presented over the next several days at the American Society of Clinical Oncology 2000 annual meeting May 20-23 in New Orleans.
    - May 19 9:00 AM ET


  1708. [05/13/2000] Really Randoms: Wyclef Jean, Chuck D (Rolling Stone)
    Wyclef Jean is the first act tapped to play at ~~~To Amadou With Love: A Night of Healing~~~ on June 19 at New York City`s Hammerstein Ballroom. The benefit concert honors the memory of the West African native shot and killed by New York Police last year. Actresses Rosie Perez and Glenn Close are both scheduled to appear and additional musical guests will be announced in coming weeks. The show`s promoters claim the benefit will be ~~~an evening that celebrates life, unity, racial and ethnic harmony, non-violence and healing.~~~ . . .
    - May 13 5:47 AM ET


  1709. [05/12/2000] Vical Announces Independent Drug Safety Review Board (Business Wire)
    Vical Inc. announced today that an independent Drug Safety Review Board has recommended that current Phase II and Phase III registration trials targeting metastatic melanoma should progress as planned, based on a review of safety and preliminary efficacy data collected to date.
    - May 12 11:34 AM ET


  1710. [05/05/2000] Brain Tumors: New Hope, New Treatments a `Cutting Edge Medical Report` iTV Special Premieres on The Health Network May 6 (PR Newswire)
    Severe headaches, memory lapses, a change in personality.
    - May 05 4:13 PM ET


  1711. [05/04/2000] New Yorkers, Catholics Mourn Cardinal O`Connor (Reuters)
    Tributes to Cardinal John O`Connor poured in on Thursday as the city mourned its influential Roman Catholic leader who died peacefully on Wednesday night after a long illness.
    - May 04 3:36 PM ET


  1712. [05/04/2000] New Yorkers, Catholics Mourn Cardinal O`Connor (Reuters)
    New Yorkers and Roman Catholics on Thursday mourned and praised Cardinal John O`Connor, the influential spiritual leader of the city`s Catholics who died peacefully Wednesday night after a long illness.
    - May 04 11:14 AM ET


  1713. [05/04/2000] Vatican Says N.Y. Cardinal Was `Faithful Shepherd` (Reuters)
    Pope John Paul was deeply saddened by the death of New York Cardinal John O`Connor and described him as ``a truly faithful shepherd`` of the Roman Catholic Church, the Vatican said on Thursday.
    - May 04 9:05 AM ET


  1714. [05/04/2000] Pope Says NY`s O`Connor Helped Him (Reuters)
    Pope John Paul II Thursday expressed his sadness over the death of New York Cardinal John O`Connor, saying he felt a sense of deep personal loss.
    - May 04 9:23 AM ET


  1715. [05/04/2000] N.Y. Cardinal John O`Connor Dies (Associated Press)
    During 16 years at the helm of the nation`s most prominent Catholic pulpit, Cardinal John O`Connor inspired a flock of millions by preaching compassion, helping the poor and fighting a brave public battle against the brain tumor that would kill him.
    - May 04 7:26 AM ET


  1716. [05/03/2000] N.Y.`s Cardinal O`Connor Dead at 80 (Reuters)
    Cardinal John O`Connor, the conservative spiritual leader of the second largest diocese in the United States, died on Wednesday at the age of 80 after months of ill health, church officials said.
    - May 03 10:14 PM ET


  1717. [05/04/2000] N.Y.`S Cardinal O`Connor Dies; Compassion Praised (Reuters)
    Cardinal John O`Connor, the conservative and charismatic spiritual leader of the Roman Catholic Church`s New York Diocese, died peacefully on Wednesday at the age of 80 after months of ill health.
    - May 04 4:21 AM ET


  1718. [05/04/2000] N.Y. Cardinal John O`Connor Dies (Associated Press)
    During 16 years at the helm of the nation`s most prominent Catholic pulpit, Cardinal John O`Connor inspired a flock of millions by preaching compassion, helping the poor and fighting a brave public battle against the brain tumor that would kill him.
    - May 04 4:03 AM ET


  1719. [05/04/2000] N.Y.`S Cardinal O`Connor Dies; Compassion Praised (Reuters)
    Cardinal John O`Connor, the conservative and charismatic spiritual leader of the Roman Catholic Church`s New York Diocese, died peacefully on Wednesday at the age of 80 after months of ill health.
    - May 04 1:04 AM ET


  1720. [05/04/2000] Eulogies Pour in for O`Connor, Clinton Lauds Him (Reuters)
    President Clinton said he was saddened to learn of the death on Wednesday of Roman Catholic Cardinal John O`Connor, head of the New York diocese, praising his lifelong commitment to helping the poor.
    - May 04 1:23 AM ET


  1721. [05/03/2000] Chronology of Cardinal O`Connor (Associated Press)
    With AM-Obit-O`Connor, By The Associated Press
    - May 03 10:25 PM ET


  1722. [05/03/2000] New York`s Cardinal John O`Connor Dies (Reuters)
    Cardinal John O`Connor, the conservative spiritual leader of the Roman Catholic Church`s New York Diocese, died on Wednesday at the age of 80 after months of ill health.
    - May 03 10:46 PM ET


  1723. [05/03/2000] Clinton Praises N.Y. Cardinal`s Commitment to Poor (Reuters)
    President Clinton said he was saddened to learn of the death on Wednesday of Roman Catholic Cardinal John O`Connor, head of the New York diocese, praising his lifelong commitment to helping the poor.
    - May 03 11:15 PM ET


  1724. [05/03/2000] 30 Years Later, the Pain of Kent State Remains (APBnews.com)
    KENT, Ohio (APBnews.com) -- I was at home watching Who Wants to Be a Millionaire not long ago when host Regis Philbin popped the $32,000 question on a contestant: What event inspired the Crosby, Stills, Nash and Young song ~~~Ohio~~~?
    - May 03 8:37 PM ET


  1725. [05/03/2000] N.Y. Cardinal John O`Connor Dies (Associated Press)
    Cardinal John O`Connor, who charmed New Yorkers with his wit and warmth while using his opposition to abortion and homosexuality to make headlines and chastise politicians, died Wednesday. He was 80.
    - May 03 10:10 PM ET


  1726. [05/03/2000] Church Says NY`s Cardinal O`Connor Near Death (Reuters)
    Cardinal John O`Connor, the conservative spiritual leader of one of the largest dioceses in the United States, was near death on Wednesday following months of ill health.
    - May 03 5:44 PM ET


  1727. [05/03/2000] Report: Cardinal O`Connor Near Death (Associated Press)
    Cardinal John O`Connor, ailing since he underwent brain surgery last summer, was near death Wednesday, his spokesman said.
    - May 03 5:02 PM ET


  1728. [05/03/2000] Cardinal O`Connor Is Near Death (Associated Press)
    Cardinal John O`Connor, ailing since he underwent brain surgery last summer, was near death Wednesday, his spokesman said.
    - May 03 5:32 PM ET


  1729. [05/02/2000] Innovative Cardiac Catheterization and Angioplasty Reaches Heart Through Wrist (PR Newswire)
    Back outside walking the next day~~~ and ~~~didn`t miss a day of work~~~ are not ways in which patients who have undergone coronary catheterization and angioplasty typically describe the experience.
    - May 02 1:48 PM ET


  1730. [05/02/2000] Photoelectron Corporation Announces First ACCUBEAM(TM) System Order From Prestigious European Neuroscience Institute (PR Newswire)
    Photoelectron Corporation,, developer of a miniature x-ray system for tumor therapy, announced today that an order for an ACCUBEAM(TM) System was received by Photoelectron`s partner, Carl Zeiss, from The International Neuroscience Institute Hannover, Germany.
    - May 02 9:01 AM ET


  1731. [04/28/2000] American Brain Tumor Association Awards $680,000 for Cutting Edge Research (PR Newswire)
    The American Brain Tumor Association, a national organization which exists to eliminate brain tumors through research and to meet the needs of brain tumor patients and their families, announces a commitment of $680,000 to fund the research efforts of 12 scientists at renowned institutions in the United States and Canada.
    - Apr 28 4:59 PM ET


  1732. [04/27/2000] The Melanoma Research Foundation Sponsors Nationwide Events for Melanoma Awareness Month (PR Newswire)
    Finding a cure for the most deadly form of skin cancer is the force behind Melanoma Awareness Month in May.
    - Apr 27 8:06 AM ET


  1733. [04/26/2000] Latest Hollywood script deals (Reuters)
    Warner Bros. Pictures has acquired the feature rights to Michael Palmer`s bestselling medical thriller ``The Patient`` for the production company headed by ``ER`` star Noah Wyle.
    - Apr 26 4:18 AM ET


  1734. [04/19/2000] Treatment hope for hormone disorder (Reuters)
    A drug that blocks the action of growth hormones may offer a new treatment for people with acromegaly, a rare hormonal disorder that spurs abnormal bone growth and tissue swelling in middle-aged adults, researchers report.
    - Apr 19 9:15 PM ET


  1735. [04/19/2000] Neurocrine Biosciences Announces Positive Findings in Phase I/II Malignant Brain Tumor Clinical Trial (Business Wire)
    Neurocrine Biosciences Inc. Wednesday announced results from a Phase I/II clinical trial in patients with advanced malignant glioma.
    - Apr 19 7:30 AM ET


  1736. [04/17/2000] Fairview-University Brain Tumor Center Holds Symposium (PR Newswire)
    The Fairview-University Brain Tumor Center will hold its first annual Upper Midwest Brain Tumor Symposium May 5 and 6 at the Minneapolis/St. Paul Airport Hilton.
    - Apr 17 11:38 AM ET


  1737. [04/13/2000] Therapy toxic, but promising for head and neck cancer (Reuters)
    A grueling regimen of chemotherapy and radiation can cure many cases of advanced head and neck cancer, results of a new study suggest. Besides improving survival, the treatment also reduces the need for aggressive surgery to remove the cancer, researchers report.
    - Apr 13 10:32 PM ET


  1738. [04/11/2000] Guilford Receives Milestone Payment For Regulatory Approval of Gliadel(R) Wafer in Spain (PR Newswire)
    Guilford Pharmaceuticals Inc. today announced that it has received a $1 million milestone payment from Aventis S.A. for regulatory approval of GLIADEL(R) Wafer in Spain.
    - Apr 11 8:30 AM ET


  1739. [03/28/2000] Chemotherapy Can Dull Mental Ability -U.S. Study (Reuters)
    Standard doses of chemotherapy can lead to permanent mental impairment for some patients, new research released on Tuesday showed.
    - Mar 28 4:07 PM ET


  1740. [03/29/2000] General Hospital Medical Staff Promotes Safety and Violence Prevention Through New Community Health Program (PR Newswire)
    The medical staff of the General Hospital Center at Passaic, part of Atlantic Health System, has inaugurated a new community health program designed to educate and promote prevention of health disease and illness.
    - Mar 29 1:54 PM ET






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