Brain Tumor Treatments: ONC-201
Braintumor Website

Last updated: 3/22/18

ONC201 is an experimental, orally bioavailable, first-in-class small molecule with demonstrated antitumor activity in preclinical models of difficult-to-treat solid and liquid tumors without imparting significant toxicity.

Clinical Trials

  1. ONC-201 for Recurrent Glioblastomas and H3 K27M-mutant Gliomas.
  2. ONC201 in Adults With Recurrent H3 K27M-mutant Glioma
  3. ONC201 in Pediatric H3 K27M Gliomas

Scientific Publications

  1. Research Abstracts presented at 2018 AACR meeting


  1. Dr. Minesh Mehta Speaks About Neuro-Oncology and the Opportunities Presented by ONC201

  2. Phase II Trial in Glioblastoma with ONC201, a First in Class DRD2 Antagonist

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