Race influences survival in glioblastoma patients with KPS =?80 and associates with genetic markers of retinoic acid metabolism.
This study shows a very large racial disparity - this time favoring African Americans. They identified a set of genes that differed between the two groups, which may be responsible. This difference is larger than most clinical trials would report as a successful treatment. It may be worth reporting clinical trial results by race and/or this group of genes now.
Historically, African Americans have been way underrepresented in clinical trials – as shown by this study. Out of almost 1,000 patients, only 6% were African American - while in the USA African Americans make up about 13% of the population. We are working to try to correct that – and other – disparities.
Posted on: 02/13/2019
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