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Vion to Proceed with a Phase I Clinical Trial of Its Third Anticancer Agent (PR Newswire)...VNP40101M also exhibited excellent penetration across the blood brain barrier in mice, and a high degree of antitumor activity against intra-cranially implanted leukemia cells.......The latter distinguishes VNP40101M from many anticancer agents that have difficulty penetrating into the brain, a site where primary tumors can occur and a common site of metastases for several other solid tumors....- Feb 20 8:24 AM ET

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