Survival in Patients with Glioblastoma Receiving Valganciclovir
Very Important Article. First the warnings: 1. this is a small study, funded in part by the company that makes the drug. 2. It was not randomized, and there was no control group - they compare to historical cotnrols.. 3. We have seen other treatments do very well in small, selected patients then not do well in large controlled trials.
Having said that, these results are outstanding, doubling the average survival time by using a simple, easily available (but expensive) anti-viral pill. It is probably too soon to say we should try it but I would say it definately needs another trial, and I wouldn't hesitate to enter the trial if I had a gbm.
For more background, read the articles on virtualtrials.com on this concept: Click HERE and here and HERE
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Original Source: http://www.nejm.org/doi/full/10.1056/NEJMc1302145
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