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Model T muscle CARs can treat brain tumors.

Al's Comment:

As I mentioned a few issues ago, the IL13Ra2 antigen is one of my favorite targets. I will be watching this.

Posted on: 09/29/2012

Clin Cancer Res. 2012 Sep 27. [Epub ahead of print]

Model T muscle CARs can treat brain tumors.

Johnson LA.


Duke Brain Tumor Immunotherapy Program, Department of Surgery, Duke University Medical Center.


Despite standard treatment with resection, radiation and chemotherapy, glioblastoma (GBM) remains a deadly disease with a dismal prognosis. Redirecting patient T cells to target the GBM-associated antigen, IL13Rα2, offers a promising translational immunotherapy with the potential to make a meaningful impact for patients with this disease.

[PubMed - as supplied by publisher]


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