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Winthrop Study For Patients With Brain Tumors

Posted on: 09/29/2011

Winthrop Study For Patients With Brain Tumors

2011-09-30 / Community

Winthrop-University Hospital Clinical Trials Center and Jai Grewal, MD, a neuro-oncologist from Winthrop, are conducting a clinical trial of an investigational drug for patients with recurrent (relapsed) malignant brain tumors, including anaplastic astrocytomas and glioblastomas. Dr. Grewal is seeking patients whose brain tumors have grown or come back, despite previous treatment with surgery and radiotherapy and/or chemotherapy.

To be eligible for the study, participants must be 18 - 70 years of age and must have a tumor that measures greater than 1 cm in volume (seen in a MRI). They will be randomly assigned to either the experimental treatment or standard of care. All individuals enrolled in the trial will receive some form of treatment. The experimental treatment involves the placement of a catheter into the brain tumor into which a research medication targeting TGF-Beta will be infused slowly over several days.

Eligible participants may receive surgery to insert the delivery system of the drug, the study drug and study procedures at no cost to them.


To find out if you qualify or for further information, please call Kimberly Byrnes, clinical trial coordinator at Winthrop- University Hospital Clinical Trials Center, (516) 663-9582 or e-mail

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