Oncolin Therapeutics Announces the Discovery of a New More Effective Anti-Cancer Treatment in Experimental Brain Tumor Models
HOUSTON--(BUSINESS WIRE)--Oncolin Therapeutics, Inc., (OTCBB:OCOL) announces that a team of scientists supported by an Oncolin Sponsored Research Agreement (SRA) and lead by Professor Waldemar Priebe from The University of Texas M. D. Anderson Cancer Center (UTMDACC) has discovered a new inhibitor of glycolysis, which is superior to the other known inhibitors. These results were confirmed both in vitro as well as in vivo brain tumor models. These new results have demonstrated that the compound that Oncolin in collaboration with UTMDACC are currently developing clearly displays significantly better pharmacokinetics, increased potency and efficacy.
“These data allows Oncolin to identify the potential clinical lead candidate for filing an IND with the FDA as soon as the preclinical studies will be completed,” said Dr Donald Picker, COO of the company.
The founding scientists at MD Anderson have designed a drug that passes through the Blood Brain Barrier (BBB), a protective tissue which prevents most other drugs from entering the brain, where this drug is then retained in brain tumor cells selectively blocking the tumors metabolic machinery. This compound class also provides higher drug uptake and a longer drug half life. This drug class can also be used to treat other cancers that depend on glycolysis for survival such as breast and pancreatic cancers. This technology is covered under Oncolin’s recent exclusive option to license agreement from The University of Texas M.D. Anderson Cancer Center, the # 1 cancer treatment center in the United State according to U.S. News and World Report.
About Oncolin Therapeutics, Inc.
Headquartered in Houston, Texas, Oncolin Therapeutics, Inc. is a publicly traded biopharmaceutical company that engages in the discovery, development and commercialization of novel selective anticancer therapies. Additional information about Oncolin can be found on the web at www.oncolinthera.com.
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