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Panzem Gets Orphan Drug Status for Glioblastoma Multiforme


Posted on: 07/31/2006

Source: press release

Panzem Gets Orphan Drug Status for Glioblastoma Multiforme

The U.S. Food and Drug Administration (FDA) has granted orphan drug status to Entremed for their agent Panzem (2-methyoxyestradiol) for the treatment of glioblastoma multiforme (GBM).

The designation of orphan drug status was based on in vitro studies that demonstrated anti-proliferative activity against glioma cell lines, and anti-tumor activity in in vivo studies involving a preclinical model of glioblastoma.

Panzem has also previously been granted orphan drug status for multiple myeloma and ovarian cancer


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