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Gamma Knife Radiosurgery for Metastatic Brain Tumors

Posted on: 10/16/2002

Citation : 13th Meet World Soc Stereotact Funct Neurosurg, Adelaide 2001. Stereotact Funct Neurosurg 2001;76:201-203

Gamma Knife Radiosurgery for Metastatic Brain Tumors

Author(s): Yong Gou Park, Jae Young Choi, Jin Woo Chang, Sang Sup Chung

Abstract : We reviewed our series of metastatic brain tumors treated by Gamma Knife Radiosurgery. From May 1992 to January 2001, 115 consecutive patients with 425 lesions were treated over 128 treatment sessions. Forty three patients were known to have died at the end of the recording period. The mean follow-up duration was 11.6 months and mean number of lesions was 3.5. The most common primary sites were lung and breast. Mean tumor volume was 4.2 cm3 and mean margin dose was 16.2 Gy. 6-month, 1-year, and 18-month survival rates were 73.6, 58, and 46%, respectively. Multivariate analysis revealed that higher KPS scores, no evidence of extracranial metastasis, and controlled primary disease were significantly related to longer survival. Adjuvant whole brain irradiation did not significantly influence on the prolongation of survival time and local control of radiosurgically treated lesions.

Copyright (c) 2002 S. Karger AG, Basel

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