News Story: Full Text
Sponsored By
Orbus Therapeutics Inc Clinical Trial for Recurrent Anaplastic Astrocytomas
Please Click On The Above Banner For More Details
Braintumor Website

Brain tumor gene target found

Al Musella's Comments: (This is his personal views and are not necessarily the views of the Musella Foundation!)


Posted on: 06/23/2004

Brain tumor gene target found

Los Angeles, CA, Jun. 22 (UPI) -- Laminin-8 genes and their resulting protein may be effective targets in fighting malignant brain tumors, an international research team has found.

Researchers led by the Cedars-Sinai Maxine Dunitz Neurosurgical Institute found over-expression of laminin-8 can predict a tumor's grade, recurrence and the patient's survival chances.

The thin membrane under the surface of blood vessels contains proteins called laminins. Researchers found during tumor progression, laminin-9, which is weakly expressed in normal brain tissue and low-grade tumors, switched to laminin-8, whose expression increased significantly with progression.

Researchers analyzed normal brain tissue and brain tumor tissue and found higher laminin-8 levels in more advanced tumors, which related to faster tumor recurrence after tumor-removal surgery and shorter patient survival times

Click HERE to return to brain tumor news headlines

Home | Brain Tumor Guide | FAQs | Find A Treatment
Noteworthy Treatments | News | Virtual Trial | Videos | Novocure Optune® | Newsletter
Donations | Brain Tumor Centers | Survivor Stories | Temodar®
Fundraising For Research | Unsubscribe | Contact Us

Copyright (c) 1993 - 2020 by:
The Musella Foundation For Brain Tumor Research & Information, Inc
1100 Peninsula Blvd
Hewlett, NY 11557