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Malignancy in a vestibular schwannoma. Report of a case with central neurofibromatosis, treated by both stereotactic radiosurgery and surgical excision, with a review of the literature.


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Website: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=Text&DB=PubMed

Posted on: 12/04/2002

1: Br J Neurosurg 2002 Jun;16(3):284-9

Malignancy in a vestibular schwannoma. Report of a case with central neurofibromatosis, treated by both stereotactic radiosurgery and surgical excision, with a review of the literature.

Bari ME, Forster DM, Kemeny AA, Walton L, Hardy D, Anderson JR.

Department of Neurosurgery, Royal Hallamshire Hospital, Sheffield, UK.

Malignant change in schwannoma is rare. Malignant change in a vestibular schwannoma (acoustic neuroma) is even more rare. This paper presents a case of rapidly growing vestibular schwannoma first treated by radiosurgery whose histopathology after surgical excision 42 months later showed malignant changes.

Up to now, eight cases of malignancy in eighth nerve tumours have been reported, four of which, including the present case, had previously been treated with radiosurgery and four cases that had not received radiation. Thus, it would seem, the overall incidence is extremely low. Nevertheless, extreme vigilance and careful reporting continues to be necessary.

Publication Types:

Review

Review of Reported Cases



PMID: 12201399 [PubMed - indexed for MEDLINE]




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