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Note: The comments under each article title are the opinion of our president, Al Musella, DPM, and do not reflect official policy of the Musella Foundation!

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05/25/18 Superselective intraarterial cerebral infusion of cetuximab with blood brain barrier disruption combined with Stupp Protocol for newly diagnosed glioblastoma.        

 This is only 1 case report but it shows great results using an old drug in a new way.




05/25/18 Midatech Pharma Commences First In-Human Study Of Brain Cancer Drug        

 This is a new way to get drugs to the tumor!




05/24/18 Brain Tumor Awareness Month Webinar Series: Special Guest Dr Eric T. Wong, MD, Co-Director, Brain Tumor Center, Beth Israel Deaconess Medical Center (Sunday 5/27/18) 7pm Eastern Time!        

 This is the final speaker in our Brain Tumor Awareness Month Webinar Series!  Dr. Wong was in charge of the USA trials for Optune and will discuss all aspects of the use of Optune for brain tumors!




05/24/18 Heat shock protein peptide complex-96 vaccination for newly diagnosed glioblastoma: a phase I, single-arm trial.        

 Pretty good results, but it is in a small trial.   




05/24/18 Patterns of care and outcomes of chemoradiation versus radiation alone for MGMT promoter unmethylated glioblastoma.        

 This study says that for glioblastoma patients with unmethylated MGMT, adding Temodar to radiation does not improve survival or progression free survival.    This is a retrospective study that does not control for other factors, but it is interesting. It opens the door for experimenting with other treatments for newly diagnosed MGMT unmethylated patients, such as perhaps substituting Val-083 instead of Temodar.




05/23/18 MimiVax Announces Positive Interim Results from Phase II Trial of SurVaxM Immunotherapy for the Treatment of Newly Diagnosed Glioblastoma        

 Excellent results with a simple shot in the arm -and minimal side effects. This is the type of treatment that we need access to now - not years from now.




05/23/18 New Published Evidence for Deadly High-Grade Gliomas Linked to Improved Survival        

 This paper shows that the new hi-tech tools from NICO allow for the removal of deep tumors in a safer way than before. It is FDA cleared, so neurosurgeons can use it now.

 




05/22/18 House approves 'right to try,' sends bill to Trump's desk        

 This is the bill we asked you to help with by calling and writing your representatives!  

Thanks for your help!






05/20/18 URGENT ACTIVISM ALERT: Right To Try Bill up for vote this Tuesday!        

 We need lots of emails and calls!  




05/18/18 Brain Tumor Awareness Month Weminar Series: Special Guest Dr Henry Friedman        

 This is an opportunity to talk to Dr Henry Friedman and ask questions on any brain tumor related topics!




05/18/18 House to vote on 'right to try' bill next week        

 I have changed my mind on this topic. I now support the bill 100% and encourage you to call  or email your representatives and ask them to vote FOR this act! Go to https://www.house.gov/representatives/find-your-representative to look up your representative.  Let me know if you send a letter or call.




05/18/18 Webinar: Navigating the New Normal After a Brain Cancer Diagnosis        

 From our friends at Tocagen.  Dr. Lovely earned her PhD at the University of California San Francisco (UCSF) School of Nursing focusing on symptom management and brain tumor patient care.




05/17/18 Support for Legislation Increasing Awareness for DIPG        

 This is from our friends at Oncoceutics and Jack's Angels Foundation.  Please contact your representatives and ask them to support this bill to create a national DIPG awareness day. (DIPG is a devestating brain tumor usually found in children)




05/16/18 Duane A. Mitchell, M.D., Ph.D., World-Renowned Immunotherapy Expert to Speak at Seattle “Brains Matter” Dinner        

 From our good friends at the End Brain Cancer Initiative! 






05/13/18 Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas        

 This is only in lab rats, but looks very promising.  They did note that the treatments caused death because of too much swelling in a small number of the rats - that will have to be watched and treated early when they start in humans, but this has the potential to be a huge breakthrough.




05/13/18 When did the glioblastoma start growing, and how much time can be gained from surgical resection? A model based on the pattern of glioblastoma growth in vivo.        

 Fascinating. We get this question all of the time. The answer is it takes about a year for the gbm to grow to the size where it causes symptoms and you notice it.   And there is a big gain from removing 99% of the tumor compared to 95%.  If they only remove 50% of the tumor, it will grow back before the surgery heals.






05/03/18 Durham firm with innovative brain cancer treatment lights up $642K equity round        

 I did not see research results but the methodology looks very interesting




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