Clinical Trial Details
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NCT02849171 : Assessing 11C-Choline (11C-CH) PET to Distinguish True Tumor Progression From Pseudoprogression in High-grade Gliomas
AgesMin: 18 Years Max: N/A
Inclusion Criteria:

- Age = 18 years

- Patient is able to provide written informed consent prior to study registration

- Histologically-confirmed high-grade glioma

- Completion of treatment with standard radiation (with or without concurrent therapy).

- Standard gadolinium-enhanced MRI changes that are considered indeterminate for tumor
progression vs. treatment-related changes by the neuroradiologist or clinician within
24 weeks of completion of radiation.

Exclusion Criteria:

- Inability to undergo or cooperate with an MRI or PET scan (e.g., claustrophobia, metal

- Renal insufficiency with recent (<3 month old) creatinine > 2.0 mg/dL

- Pregnant or nursing female
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