Clinical Trial Details
Braintumor Website

[Information provided by: ClinicalTrials.gov, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT02764151 : First in Patient Study for PF-06840003 in Malignant Gliomas
PhasePhase 1
AgesMin: 18 Years Max: N/A
Eligibility
Inclusion Criteria:

- Diagnosis of WHO Grade IV glioblastoma or WHO Grade III anaplastic glioma

- Recurrent disease at the time of the first or second recurrence or progression

- Karnofsky performance score greater than or equal to 70%

- Adequate bone marrow, kidney and liver function

Exclusion Criteria:

- History of CNS bleeding within 6 months of registration

- Previous anti-angiogenics or anti-vascular endothelial growth factor

- Requires treatment with high dose systemic corticosteroids defined as >2 mg/day

- Radiation therapy within 12 weeks of registration
LinksPermanent Link to THIS page: http://virtualtrials.com/nct/display1trial.cfm?nct=NCT02764151      |      Link to official Clinicaltrials.gov listing
Locations
Los Angeles, California
Facility: Ronald Reagan UCLA Medical Center, Drug Information Center
Investigator:
Contact:
Email not avaialable

Los Angeles, California
Facility: Ronald Reagan UCLA Medical Center
Investigator:
Contact:
Email not avaialable

Los Angeles, California
Facility: UCLA Clinical & Translational Research Center
Investigator:
Contact:
Email not avaialable

Los Angeles, California
Facility: UCLA Oncology Center
Investigator:
Contact:
Email not avaialable

Los Angeles, California
Facility: UCLA School of Medicine
Investigator:
Contact:
Email not avaialable

Durham, North Carolina
Facility: Duke Cancer Center
Investigator:
Contact:
Email not avaialable

Durham, North Carolina
Facility: Duke University Medical Center, Duke Cancer Center
Investigator:
Contact:
Email not avaialable




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