Clinical Trial Details
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NCT02353000 : Whole Brain Radiotherapy (WBRT) Versus Stereotactic Radiosurgery (SRS) for 4 Upto 10 Brain Metastases
AgesMin: 18 Years Max: N/A
Inclusion Criteria:

- Minimal 4 up to a maximum of 10 BM on diagnostic MRI scan

- Max diameter of single GTV 2.5cm

- Max cumulative GTV of 30cm3

- Karnofsky performance status ? 70

- Any solid primary tumour. Small cell lung carcinoma, germinoma, and lymphoma are

- Ability to provide written informed consent

Exclusion Criteria:

- Contra-indication for MRI

- Prior treatment for BM (i.e. surgery, SRS or WBRT)

- Concurrent use of systemic therapy

- Maximum cumulative GTV of more than 30cm3 on planning-MRI

- More than 10 BM on planning-MRI

- A brainstem metastasis with a PTV of more than 20 cm3
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