Clinical Trial Details
Braintumor Website

[Information provided by: ClinicalTrials.gov, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT02353000 : Whole Brain Radiotherapy (WBRT) Versus Stereotactic Radiosurgery (SRS) for 4 Upto 10 Brain Metastases
PhaseN/A
AgesMin: 18 Years Max: N/A
Eligibility
Inclusion Criteria:

- Minimal 4 up to a maximum of 10 BM on diagnostic MRI scan

- Max diameter of single GTV 2.5cm

- Max cumulative GTV of 30cm3

- Karnofsky performance status ? 70

- Any solid primary tumour. Small cell lung carcinoma, germinoma, and lymphoma are
excluded

- Ability to provide written informed consent

Exclusion Criteria:

- Contra-indication for MRI

- Prior treatment for BM (i.e. surgery, SRS or WBRT)

- Concurrent use of systemic therapy

- Maximum cumulative GTV of more than 30cm3 on planning-MRI

- More than 10 BM on planning-MRI

- A brainstem metastasis with a PTV of more than 20 cm3
LinksPermanent Link to THIS page: http://virtualtrials.com/nct/display1trial.cfm?nct=NCT02353000      |      Link to official Clinicaltrials.gov listing
Locations
Amsterdam,
Netherlands

Facility: VUmc
Investigator:
Contact: Anna Bruynzeel, MD, Phd Phone: +31204440436
Click HERE to send email to this center

Amsterdam,
Netherlands

Facility: AMC
Investigator:
Contact: Edith Dieleman, MD Phone: +31 20 566 34 33
Click HERE to send email to this center

Den Haag,
Netherlands

Facility: Haaglanden MC
Investigator:
Contact: Ruud Wiggenraad, MD, Phd Phone: +31 70 330 2071
Click HERE to send email to this center

Maastricht,
Netherlands

Facility: Maastricht Radiation Oncology (MAASTRO clinic)
Investigator:
Contact: Jaap Zindler, MD Phone: 088 44 55 591
Click HERE to send email to this center

Rotterdam,
Netherlands

Facility: Erasmus MC
Investigator:
Contact: Annemarie Swaak, MD Phone: +31 10 70 41 347
Click HERE to send email to this center




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