Clinical Trial Details
Braintumor Website

[Information provided by: ClinicalTrials.gov, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT00887146 : Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma
PhasePhase 3
AgesMin: 18 Years Max: N/A
Eligibility
Pre-Registration Inclusion Criteria:

- United States (US) and Canadian sites:

* This review is mandatory prior to registration to confirm eligibility; patients must
be willing to submit tissue samples for mandatory central pathology review submission;
it should be initiated as soon after surgery as possible

- Tissue must have been determined to have local 1p/9q co-deletion and IDH mutation
prior to submission for central path review

- Tumor tissue must show co-deletion of chromosomes 1p and 19q; for eligibility,
the 1p/19q analysis results will be accepted from the local site, as determined
by either a locally available or reference laboratory (for US, must be Clinical
Laboratory Improvement Act [CLIA] certified); acceptable methods for
determination of 1p/19q loss include fluorescent in-situ hybridization (FISH), by
genomic sequencing or methylomic analyses; US and Canadian sites must send a copy
of the official report to the pathology coordinator and quality assurance
specialist (QAS)

- Tumor must also show evidence of IDH mutation by immunohistochemistry or genomic
analyses; this should be performed at the local site (US: performed in a CLIA
certified laboratory); the site must send a copy of the official report to the
pathology coordinator and QAS

Registration Inclusion Criteria:

- Newly diagnosed and =< 3 months from surgical diagnosis; patients are also eligible if
they have had a prior surgical procedure > 3 months earlier for low grade glioma, as
long as the patient has not received prior radiation or prior chemotherapy

- Histological evidence of World Health Organization (WHO) grade III anaplastic glioma
or WHO grade II low grade glioma with locally diagnosed combined 1p/19q loss and the
presence of an either IDH1 or IDH2, both as established by a local or referenced
laboratory qualified for the study

* Note: mixed gliomas are eligible, regardless of the degree of astrocytic or
oligodendrocytic predominance, as long as the tumor is also co-deleted for 1p and 19q

- Patients with codeleted low grade gliomas must also be considered "high risk" by
exhibiting one or more of the following characteristics:

- Age >= 40 and any surgical therapy

- Age < 40 with prior and subtotal resection or biopsy (i.e., anything less than
gross total resection)

- Documented growth following prior surgery (NOTE: patients with prior surgery
cannot have received prior radiation, chemotherapy or targeted therapy)

- Intractable seizures

- Surgery (partial or gross total resection or biopsy) must be performed >= 2 weeks
prior to registration; patient must have recovered adequately from the effects of
surgery

- Absolute neutrophil count (ANC) >= 1,500/mm^3 obtained =< 21 days prior to
registration

- Platelet (PLTs) count >= 100,000/mm^3 obtained =< 21 days prior to registration

- Hemoglobin (Hgb) > 9.0 g/dL obtained =< 21 days prior to registration

- Total bilirubin =< 1.5 x institutional upper limit of normal (ULN) obtained =< 21 days
prior to registration

- Serum glutamic oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) =< 3
x ULN obtained =< 21 days prior to registration

- Creatinine =< 1.5 x ULN obtained =< 21 days prior to registration

- Negative serum or urine pregnancy test done =< 7 days prior to registration, for women
of childbearing potential only

- Willingness and ability to personally complete neurocognitive testing (without
assistance) and willingness to complete the QOL testing, (either personally or with
assistance)

- Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0, 1 or 2

- Written informed consent

- Willingness to return to enrolling institution for follow-up during the active
monitoring phase (that is, the active treatment and observation portion) of the
study); patients who have been formally transferred to another active and approved
site participating in this study would not need to return to the enrolling institution
for this purpose

- Willingness to allow the provision of tissue samples for correlative research, as long
as adequate tissues are available; patients will not be excluded from participation in
the study, if they are willing to allow provision of tissues for the correlative
research, but there are insufficient quantities of tissue for the correlative analyses
(e.g., a patient otherwise eligible and willing who had biopsy only) Willingness to
allow the provision of blood samples for correlative research; patients are not
excluded from participation in the study, if they are willing to provide the mandatory
biospecimens for translational/correlative research, but for logistical reasons the
specimens(s) were not obtainable or if the volume collected was insufficient

Registration Exclusion Criteria:

- The following categories are ineligible:

- Pregnant women

- Nursing women

- Men or women of childbearing potential who are unwilling to employ adequate
contraception or contraceptive method during this study and 6 months following
the completion of chemotherapy treatments

- History of prior radiation therapy or chemotherapy for glioma; note: patients who have
a history of prior low grade glioma (with or without a distant history of prior
surgery for that glioma), but who have never received prior chemotherapy or radiation
therapy for the glioma are eligible for the study

- Co-morbid systemic illnesses or other severe concurrent disease which, in the judgment
of the investigator, would make the patient inappropriate for entry into this study or
interfere significantly with the proper assessment of safety and toxicity of the
prescribed regimens

- Concomitant serious immunocompromised status (other than that related to concomitant
steroids) that would compromise the safety of the patient on the study

- Patients known to be human immunodeficiency virus (HIV) positive and currently
receiving retroviral therapy are not eligible; note: patients known to be HIV
positive, but without clinical evidence of an immunocompromised state, are eligible
for the study

- Uncontrolled intercurrent illness including, but not limited to, ongoing or active
infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac
arrhythmia, or psychiatric illness/social situations that would limit compliance with
study requirements

- Receiving any other investigational agent that would be considered as a treatment for
the primary neoplasm

- Other active malignancy within 5 years of registration; exceptions: non-melanotic skin
cancer or carcinoma-in-situ of the cervix; note: if there is a history of prior
malignancy, the patient is not eligible if they are receiving other specific treatment
(with the exclusion of hormonal therapy or Her-2 inhibitors) for their cancer or if
they have received prior total body irradiation which included the brain

- History of myocardial infarction =< 6 months, or congestive heart failure requiring
use of ongoing maintenance therapy for life-threatening ventricular arrhythmias

- Recent history of hepatitis infection or if the treating physician determined that the
patient would be at significant risk of reactivation of hepatitis
LinksPermanent Link to THIS page: https://virtualtrials.com/nct/display1trial.cfm?nct=NCT00887146      |      Link to official Clinicaltrials.gov listing
Locations
Vienna,
Austria

Facility: Medical University Vienna
Investigator: Kurt A. Jaeckle
Contact: Kurt A. Jaeckle
Email not avaialable

Antwerpen,
Belgium

Facility: Alegemeen Ziekenhuis Middelheim
Investigator: Kurt A. Jaeckle
Contact: Kurt A. Jaeckle Phone: 904-953-7102
Click HERE to send email to this center

Lyon,
France

Facility: Centre Leon Berard
Investigator: Kurt A. Jaeckle
Contact: Kurt A. Jaeckle
Email not avaialable

Nice,
France

Facility: Centre Antoine Lacassagne
Investigator: Kurt A. Jaeckle
Contact: Kurt A. Jaeckle Phone: 904-953-7102
Click HERE to send email to this center

Villejuif,
France

Facility: Gustave Roussy
Investigator: Kurt A. Jaeckle
Contact: Kurt A. Jaeckle
Email not avaialable

Amsterdam,
Netherlands

Facility: Academ Zienkenhuis Bij De University
Investigator: Kurt A. Jaeckle
Contact: Kurt A. Jaeckle
Email not avaialable

Groningen,
Netherlands

Facility: University Medical Center Groningen
Investigator: Kurt A. Jaeckle
Contact: Kurt A. Jaeckle
Email not avaialable

Maastricht,
Netherlands

Facility: Maastro Clinic-Maastricht Radiation Oncology
Investigator: Kurt A. Jaeckle
Contact: Kurt A. Jaeckle Phone: 904-953-7102
Click HERE to send email to this center

Rotterdam,
Netherlands

Facility: Erasmus University Medical Center
Investigator: Kurt A. Jaeckle
Contact: Kurt A. Jaeckle
Email not avaialable

Birmingham, Alabama
Facility: University of Alabama at Birmingham Cancer Center
Investigator: John B. Fiveash
Contact: John B. Fiveash Phone: 773-702-9171
Click HERE to send email to this center

Anchorage, Alaska
Facility: Anchorage Associates in Radiation Medicine
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 907-212-6871
Click HERE to send email to this center

Anchorage, Alaska
Facility: Alaska Oncology and Hematology LLC
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 907-212-6871
Click HERE to send email to this center

Anchorage, Alaska
Facility: Alaska Women's Cancer Care
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 773-702-9171
Click HERE to send email to this center

Anchorage, Alaska
Facility: Anchorage Oncology Centre
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 907-212-6871
Click HERE to send email to this center

Anchorage, Alaska
Facility: Katmai Oncology Group
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 907-212-6871
Click HERE to send email to this center

Anchorage, Alaska
Facility: Providence Alaska Medical Center
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 907-212-6871
Click HERE to send email to this center

Phoenix, Arizona
Facility: Saint Joseph's Hospital and Medical Center
Investigator: David G. Brachman
Contact: David G. Brachman Phone: 888-823-5923
Click HERE to send email to this center

Anaheim, California
Facility: Kaiser Permanente-Anaheim
Investigator: Michael R. Girvigian
Contact: Michael R. Girvigian Phone: 626-564-3455
Email not avaialable

Auburn, California
Facility: Sutter Cancer Centers Radiation Oncology Services-Auburn
Investigator: Stacy D. D'Andre
Contact: Stacy D. D'Andre Phone: 415-209-2686
Click HERE to send email to this center

Burlingame, California
Facility: Mills-Peninsula Medical Center
Investigator: Stacy D. D'Andre
Contact: Stacy D. D'Andre Phone: 415-209-2686
Click HERE to send email to this center

Cameron Park, California
Facility: Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Investigator: Stacy D. D'Andre
Contact: Stacy D. D'Andre Phone: 415-209-2686
Click HERE to send email to this center

Fresno, California
Facility: University Oncology Associates
Investigator: Uzair B. Chaudhary
Contact: Uzair B. Chaudhary Phone: 559-256-9680
Email not avaialable

Fresno, California
Facility: California Cancer Center - North Fresno
Investigator: Uzair B. Chaudhary
Contact: Uzair B. Chaudhary Phone: 559-447-4050
Email not avaialable

Los Angeles, California
Facility: Kaiser Permanente Los Angeles Medical Center
Investigator: Michael R. Girvigian
Contact: Michael R. Girvigian Phone: 626-564-3455
Email not avaialable

Los Angeles, California
Facility: Cedars Sinai Medical Center
Investigator: Jethro L. Hu
Contact: Jethro L. Hu Phone: 310-423-8965
Email not avaialable

Modesto, California
Facility: Memorial Medical Center
Investigator: Stacy D. D'Andre
Contact: Stacy D. D'Andre Phone: 415-209-2686
Click HERE to send email to this center

Roseville, California
Facility: Sutter Cancer Centers Radiation Oncology Services-Roseville
Investigator: Stacy D. D'Andre
Contact: Stacy D. D'Andre Phone: 415-209-2686
Click HERE to send email to this center

Sacramento, California
Facility: Sutter Medical Center Sacramento
Investigator: Stacy D. D'Andre
Contact: Stacy D. D'Andre Phone: 415-209-2686
Click HERE to send email to this center

Vacaville, California
Facility: Sutter Cancer Centers Radiation Oncology Services-Vacaville
Investigator: Stacy D. D'Andre
Contact: Stacy D. D'Andre Phone: 415-209-2686
Click HERE to send email to this center

Vallejo, California
Facility: Sutter Solano Medical Center/Cancer Center
Investigator: Stacy D. D'Andre
Contact: Stacy D. D'Andre Phone: 415-209-2686
Click HERE to send email to this center

Colorado Springs, Colorado
Facility: Penrose-Saint Francis Healthcare
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 303-777-2663
Click HERE to send email to this center

Denver, Colorado
Facility: Porter Adventist Hospital
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 303-777-2663
Click HERE to send email to this center

Lakewood, Colorado
Facility: Saint Anthony Hospital
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 303-777-2663
Click HERE to send email to this center

Littleton, Colorado
Facility: Littleton Adventist Hospital
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 303-777-2663
Click HERE to send email to this center

Longmont, Colorado
Facility: Longmont United Hospital
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 303-777-2663
Click HERE to send email to this center

Loveland, Colorado
Facility: McKee Medical Center
Investigator: Keren Sturtz
Contact: Keren Sturtz Phone: 303-777-2663
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Pueblo, Colorado
Facility: Saint Mary Corwin Medical Center
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 303-777-2663
Click HERE to send email to this center

New Haven, Connecticut
Facility: Yale University
Investigator: Kevin P. Becker
Contact: Kevin P. Becker Phone: 203-785-5702
Email not avaialable

Washington, District of Columbia
Facility: Sibley Memorial Hospital
Investigator: Matthias Holdhoff
Contact: Matthias Holdhoff Phone: 202-243-2373
Email not avaialable

Boca Raton, Florida
Facility: Boca Raton Regional Hospital
Investigator: Sajeel A. Chowdhary
Contact: Sajeel A. Chowdhary Phone: 561-955-4800
Email not avaialable

Gainesville, Florida
Facility: University of Florida Health Science Center - Gainesville
Investigator: David D. Tran
Contact: David D. Tran Phone: 888-823-5923
Click HERE to send email to this center

Jacksonville, Florida
Facility: Mayo Clinic in Florida
Investigator: Paul D. Brown
Contact: Paul D. Brown Phone: 855-776-0015
Email not avaialable

Atlanta, Georgia
Facility: Emory University Hospital Midtown
Investigator: Alfredo D. Voloschin
Contact: Alfredo D. Voloschin Phone: 888-946-7447
Email not avaialable

Atlanta, Georgia
Facility: Piedmont Hospital
Investigator: Adam W. Nowlan
Contact: Adam W. Nowlan Phone: 404-425-7943
Click HERE to send email to this center

Atlanta, Georgia
Facility: Emory University Hospital/Winship Cancer Institute
Investigator: Alfredo D. Voloschin
Contact: Alfredo D. Voloschin Phone: 404-778-1868
Email not avaialable

Post Falls, Idaho
Facility: Kootenai Cancer Center
Investigator: Benjamin T. Marchello
Contact: Benjamin T. Marchello Phone: 406-969-6060
Click HERE to send email to this center

Decatur, Illinois
Facility: Cancer Care Specialists of Central Illinois
Investigator: James L. Wade
Contact: James L. Wade Phone: 217-876-4740
Click HERE to send email to this center

Decatur, Illinois
Facility: Decatur Memorial Hospital
Investigator: James L. Wade
Contact: James L. Wade Phone: 217-876-6601
Email not avaialable

Effingham, Illinois
Facility: Crossroads Cancer Center
Investigator: James L. Wade
Contact: James L. Wade Phone: 217-342-2066
Email not avaialable

Pekin, Illinois
Facility: OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Investigator: James L. Wade
Contact: James L. Wade Phone: 309-353-0512
Email not avaialable

Peoria, Illinois
Facility: OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Investigator: James L. Wade
Contact: James L. Wade Phone: 609-599-5179
Email not avaialable

Peoria, Illinois
Facility: OSF Saint Francis Medical Center
Investigator: James L. Wade
Contact: James L. Wade Phone: 309-655-3258
Email not avaialable

Swansea, Illinois
Facility: Cancer Care Specialists of Illinois-Swansea
Investigator: James L. Wade
Contact: James L. Wade Phone: 217-876-4755
Click HERE to send email to this center

Fort Wayne, Indiana
Facility: Parkview Hospital Randallia
Investigator: Brian K. Chang
Contact: Brian K. Chang Phone: 260-373-8888
Click HERE to send email to this center

Mishawaka, Indiana
Facility: Memorial Regional Cancer Center Day Road
Investigator: Thomas J. Reid
Contact: Thomas J. Reid Phone: 773-702-9171
Click HERE to send email to this center

South Bend, Indiana
Facility: Memorial Hospital of South Bend
Investigator: Thomas J. Reid
Contact: Thomas J. Reid Phone: 800-284-7370
Email not avaialable

Clive, Iowa
Facility: Medical Oncology and Hematology Associates-West Des Moines
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 515-247-3970
Email not avaialable

Clive, Iowa
Facility: Mercy Cancer Center-West Lakes
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 888-823-5923
Click HERE to send email to this center

Des Moines, Iowa
Facility: Iowa Methodist Medical Center
Investigator: Robert J. Behrens
Contact: Robert J. Behrens Phone: 515-241-6727
Email not avaialable

Des Moines, Iowa
Facility: Iowa-Wide Oncology Research Coalition NCORP
Investigator: Robert J. Behrens
Contact: Robert J. Behrens Phone: 515-282-2921
Email not avaialable

Des Moines, Iowa
Facility: Medical Oncology and Hematology Associates-Des Moines
Investigator: Robert J. Behrens
Contact: Robert J. Behrens Phone: 515-282-2921
Email not avaialable

Des Moines, Iowa
Facility: Broadlawns Medical Center
Investigator: Robert J. Behrens
Contact: Robert J. Behrens Phone: 773-702-9171
Click HERE to send email to this center

Des Moines, Iowa
Facility: Medical Oncology and Hematology Associates-Laurel
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 515-247-3970
Email not avaialable

Des Moines, Iowa
Facility: Mercy Medical Center - Des Moines
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 888-221-4849
Email not avaialable

Des Moines, Iowa
Facility: Iowa Lutheran Hospital
Investigator: Robert J. Behrens
Contact: Robert J. Behrens Phone: 515-241-8704
Email not avaialable

West Des Moines, Iowa
Facility: Methodist West Hospital
Investigator: Robert J. Behrens
Contact: Robert J. Behrens Phone: 773-702-9171
Click HERE to send email to this center

West Des Moines, Iowa
Facility: Mercy Medical Center-West Lakes
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 888-823-5923
Click HERE to send email to this center

Lexington, Kentucky
Facility: University of Kentucky/Markey Cancer Center
Investigator: John L. Villano
Contact: John L. Villano Phone: 859-257-3379
Email not avaialable

Louisville, Kentucky
Facility: Norton Hospital Pavilion and Medical Campus
Investigator: Aaron C. Spalding
Contact: Aaron C. Spalding Phone: 502-629-2500
Email not avaialable

Baltimore, Maryland
Facility: Johns Hopkins University/Sidney Kimmel Cancer Center
Investigator: Matthias Holdhoff
Contact: Matthias Holdhoff Phone: 410-955-8804
Click HERE to send email to this center

Rockville, Maryland
Facility: Cancer Trials Support Unit
Investigator: Kurt A. Jaeckle
Contact: Kurt A. Jaeckle
Email not avaialable

Ann Arbor, Michigan
Facility: University of Michigan Comprehensive Cancer Center
Investigator: Michelle M. Kim
Contact: Michelle M. Kim Phone: 800-865-1125
Email not avaialable

Kalamazoo, Michigan
Facility: West Michigan Cancer Center
Investigator: Sunil Nagpal
Contact: Sunil Nagpal Phone: 616-391-1230
Click HERE to send email to this center

Burnsville, Minnesota
Facility: Fairview Ridges Hospital
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
Click HERE to send email to this center

Coon Rapids, Minnesota
Facility: Mercy Hospital
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
Click HERE to send email to this center

Duluth, Minnesota
Facility: Essentia Health Cancer Center
Investigator: Bret E. Friday
Contact: Bret E. Friday Phone: 218-786-3308
Email not avaialable

Duluth, Minnesota
Facility: Miller-Dwan Hospital
Investigator: Bret E. Friday
Contact: Bret E. Friday Phone: 888-203-7267
Email not avaialable

Edina, Minnesota
Facility: Fairview-Southdale Hospital
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
Click HERE to send email to this center

Fridley, Minnesota
Facility: Unity Hospital
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
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Maplewood, Minnesota
Facility: Minnesota Oncology Hematology PA-Maplewood
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
Click HERE to send email to this center

Maplewood, Minnesota
Facility: Saint John's Hospital - Healtheast
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 773-702-9171
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Minneapolis, Minnesota
Facility: Abbott-Northwestern Hospital
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
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Minneapolis, Minnesota
Facility: Hennepin County Medical Center
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
Click HERE to send email to this center

Robbinsdale, Minnesota
Facility: North Memorial Medical Health Center
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
Click HERE to send email to this center

Rochester, Minnesota
Facility: Mayo Clinic
Investigator: Paul D. Brown
Contact: Paul D. Brown Phone: 855-776-0015
Email not avaialable

Saint Louis Park, Minnesota
Facility: Park Nicollet Clinic - Saint Louis Park
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
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Saint Paul, Minnesota
Facility: Regions Hospital
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
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Saint Paul, Minnesota
Facility: United Hospital
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
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Shakopee, Minnesota
Facility: Saint Francis Regional Medical Center
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
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Stillwater, Minnesota
Facility: Lakeview Hospital
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
Click HERE to send email to this center

Waconia, Minnesota
Facility: Ridgeview Medical Center
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
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Willmar, Minnesota
Facility: Rice Memorial Hospital
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
Click HERE to send email to this center

Woodbury, Minnesota
Facility: Minnesota Oncology Hematology PA-Woodbury
Investigator: Daniel M. Anderson
Contact: Daniel M. Anderson Phone: 952-993-1517
Click HERE to send email to this center

Cape Girardeau, Missouri
Facility: Saint Francis Medical Center
Investigator: James L. Wade
Contact: James L. Wade Phone: 573-334-2230
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Saint Louis, Missouri
Facility: Washington University School of Medicine
Investigator: Jian L. Campian
Contact: Jian L. Campian Phone: 800-600-3606
Click HERE to send email to this center

Billings, Montana
Facility: Billings Clinic Cancer Center
Investigator: Benjamin T. Marchello
Contact: Benjamin T. Marchello Phone: 800-996-2663
Click HERE to send email to this center

Grand Island, Nebraska
Facility: CHI Health Saint Francis
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 800-998-2119
Email not avaialable

Kearney, Nebraska
Facility: CHI Health Good Samaritan
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 888-823-5923
Click HERE to send email to this center

Lincoln, Nebraska
Facility: Southeast Nebraska Cancer Center
Investigator: Gamini S. Soori
Contact: Gamini S. Soori Phone: 402-327-7363
Email not avaialable

Omaha, Nebraska
Facility: Missouri Valley Cancer Consortium
Investigator: Gamini S. Soori
Contact: Gamini S. Soori Phone: 402-991-8070
Click HERE to send email to this center

Omaha, Nebraska
Facility: Alegent Health Immanuel Medical Center
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 402-343-8511
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Omaha, Nebraska
Facility: Alegent Health Bergan Mercy Medical Center
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 402-398-6060
Email not avaialable

Omaha, Nebraska
Facility: Nebraska Cancer Specialists - Omaha
Investigator: Gamini S. Soori
Contact: Gamini S. Soori Phone: 402-393-3110
Email not avaialable

Omaha, Nebraska
Facility: Alegent Health Lakeside Hospital
Investigator: Mehmet S. Copur
Contact: Mehmet S. Copur Phone: 888-823-5923
Click HERE to send email to this center

Omaha, Nebraska
Facility: University of Nebraska Medical Center
Investigator: Nicole A. Shonka
Contact: Nicole A. Shonka Phone: 402-559-6941
Click HERE to send email to this center

Scottsbluff, Nebraska
Facility: Regional West Medical Center Cancer Center
Investigator: Gamini S. Soori
Contact: Gamini S. Soori Phone: 308-630-2429
Email not avaialable

Las Vegas, Nevada
Facility: Radiation Oncology Centers of Nevada Central
Investigator: John A. Ellerton
Contact: John A. Ellerton Phone: 702-384-0013
Email not avaialable

Las Vegas, Nevada
Facility: 21st Century Oncology
Investigator: John A. Ellerton
Contact: John A. Ellerton Phone: 702-384-0013
Email not avaialable

Las Vegas, Nevada
Facility: Comprehensive Cancer Centers of Nevada
Investigator: John A. Ellerton
Contact: John A. Ellerton Phone: 702-384-0013
Email not avaialable

Reno, Nevada
Facility: Renown Regional Medical Center
Investigator: John A. Ellerton
Contact: John A. Ellerton Phone: 702-384-0013
Email not avaialable

Reno, Nevada
Facility: Saint Mary's Regional Medical Center
Investigator: John A. Ellerton
Contact: John A. Ellerton Phone: 773-702-9171
Click HERE to send email to this center

Albuquerque, New Mexico
Facility: University of New Mexico Cancer Center
Investigator: Olivier Rixe
Contact: Olivier Rixe Phone: 505-925-0366
Click HERE to send email to this center

Brooklyn, New York
Facility: New York-Presbyterian/Brooklyn Methodist Hospital
Investigator: Sameer Rafla-Demetrious
Contact: Sameer Rafla-Demetrious Phone: 718-780-3677
Click HERE to send email to this center

New York, New York
Facility: Columbia University/Herbert Irving Cancer Center
Investigator: Andrew B. Lassman
Contact: Andrew B. Lassman Phone: 212-305-8615
Email not avaialable

Rochester, New York
Facility: Highland Hospital
Investigator: Yuhchyau Chen
Contact: Yuhchyau Chen Phone: 585-341-8113
Email not avaialable

Rochester, New York
Facility: University of Rochester
Investigator: Yuhchyau Chen
Contact: Yuhchyau Chen Phone: 585-275-5830
Email not avaialable

Winston-Salem, North Carolina
Facility: Wake Forest University Health Sciences
Investigator: Glenn J. Lesser
Contact: Glenn J. Lesser Phone: 336-713-6771
Email not avaialable

Cleveland, Ohio
Facility: Cleveland Clinic Foundation
Investigator: Samuel T. Chao
Contact: Samuel T. Chao Phone: 866-223-8100
Email not avaialable

Columbus, Ohio
Facility: Ohio State University Comprehensive Cancer Center
Investigator: Vinay K. Puduvalli
Contact: Vinay K. Puduvalli Phone: 800-293-5066
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Columbus, Ohio
Facility: Riverside Methodist Hospital
Investigator: Timothy D. Moore
Contact: Timothy D. Moore Phone: 614-566-4475
Email not avaialable

Columbus, Ohio
Facility: The Mark H Zangmeister Center
Investigator: Timothy D. Moore
Contact: Timothy D. Moore Phone: 773-702-9171
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Columbus, Ohio
Facility: Mount Carmel Health Center West
Investigator: Timothy D. Moore
Contact: Timothy D. Moore Phone: 614-234-5433
Email not avaialable

Mayfield Heights, Ohio
Facility: Hillcrest Hospital Cancer Center
Investigator: Samuel T. Chao
Contact: Samuel T. Chao Phone: 440-312-4293
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Sylvania, Ohio
Facility: Flower Hospital
Investigator: Abhijit B. Saste
Contact: Abhijit B. Saste Phone: 419-824-1842
Email not avaialable

Westerville, Ohio
Facility: Saint Ann's Hospital
Investigator: Timothy D. Moore
Contact: Timothy D. Moore Phone: 773-702-9171
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Wooster, Ohio
Facility: Cleveland Clinic Wooster Family Health and Surgery Center
Investigator: Samuel T. Chao
Contact: Samuel T. Chao Phone: 800-862-7798
Email not avaialable

Oklahoma City, Oklahoma
Facility: University of Oklahoma Health Sciences Center
Investigator: Terence S. Herman
Contact: Terence S. Herman Phone: 405-271-8777
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Tulsa, Oklahoma
Facility: Oklahoma Cancer Specialists and Research Institute-Tulsa
Investigator: Terence S. Herman
Contact: Terence S. Herman Phone: 918-505-3200
Email not avaialable

Clackamas, Oregon
Facility: Clackamas Radiation Oncology Center
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 503-215-2614
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Portland, Oregon
Facility: Providence Portland Medical Center
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 503-215-2614
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Portland, Oregon
Facility: Providence Saint Vincent Medical Center
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 503-215-2614
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Abington, Pennsylvania
Facility: Abington Memorial Hospital
Investigator: Willard G. Andrews
Contact: Willard G. Andrews Phone: 215-481-2402
Email not avaialable

Bethlehem, Pennsylvania
Facility: Saint Luke's University Hospital-Bethlehem Campus
Investigator: Hugh D. Moulding
Contact: Hugh D. Moulding Phone: 888-823-5923
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Danville, Pennsylvania
Facility: Geisinger Medical Center
Investigator: Na Tosha N. Gatson
Contact: Na Tosha N. Gatson Phone: 570-271-5251
Email not avaialable

Philadelphia, Pennsylvania
Facility: Thomas Jefferson University Hospital
Investigator: Jon Glass
Contact: Jon Glass Phone: 215-955-6084
Email not avaialable

Philadelphia, Pennsylvania
Facility: Temple University Hospital
Investigator: Aruna Padmanabhan
Contact: Aruna Padmanabhan Phone: 215-728-2983
Email not avaialable

Pittsburgh, Pennsylvania
Facility: University of Pittsburgh Cancer Institute (UPCI)
Investigator: David A. Clump
Contact: David A. Clump Phone: 412-647-8073
Email not avaialable

Wilkes-Barre, Pennsylvania
Facility: Geisinger Wyoming Valley/Henry Cancer Center
Investigator: Na Tosha N. Gatson
Contact: Na Tosha N. Gatson Phone: 570-271-5251
Email not avaialable

Charleston, South Carolina
Facility: Medical University of South Carolina
Investigator: Scott M. Lindhorst
Contact: Scott M. Lindhorst Phone: 843-792-9321
Email not avaialable

Rapid City, South Dakota
Facility: Rapid City Regional Hospital
Investigator: Kathryn A. Arrambide
Contact: Kathryn A. Arrambide Phone: 605-716-3982
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Nashville, Tennessee
Facility: Vanderbilt University/Ingram Cancer Center
Investigator: Paul L. Moots
Contact: Paul L. Moots Phone: 800-811-8480
Email not avaialable

Dallas, Texas
Facility: UT Southwestern/Simmons Cancer Center-Dallas
Investigator: Edward Pan
Contact: Edward Pan Phone: 214-648-7097
Email not avaialable

Galveston, Texas
Facility: University of Texas Medical Branch
Investigator: Todd A. Swanson
Contact: Todd A. Swanson Phone: 409-772-1950
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League City, Texas
Facility: UTMB Cancer Center at Victory Lakes
Investigator: Todd A. Swanson
Contact: Todd A. Swanson Phone: 800-917-8906
Email not avaialable

Cedar City, Utah
Facility: Sandra L Maxwell Cancer Center
Investigator: Gordon A. Watson
Contact: Gordon A. Watson Phone: 435-868-5680
Email not avaialable

Murray, Utah
Facility: Intermountain Medical Center
Investigator: Gordon A. Watson
Contact: Gordon A. Watson Phone: 801-507-3950
Email not avaialable

Provo, Utah
Facility: Utah Valley Regional M edical Center
Investigator: Gordon A. Watson
Contact: Gordon A. Watson Phone: 801-357-7965
Email not avaialable

Saint George, Utah
Facility: Dixie Medical Center Regional Cancer Center
Investigator: Gordon A. Watson
Contact: Gordon A. Watson Phone: 435-688-4167
Email not avaialable

Salt Lake City, Utah
Facility: Utah Cancer Specialists-Salt Lake City
Investigator: Gordon A. Watson
Contact: Gordon A. Watson Phone: 801-933-6070
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Salt Lake City, Utah
Facility: Huntsman Cancer Institute/University of Utah
Investigator: Adam L. Cohen
Contact: Adam L. Cohen Phone: 801-581-4477
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Salt Lake City, Utah
Facility: LDS Hospital
Investigator: Gordon A. Watson
Contact: Gordon A. Watson Phone: 801-408-1347
Email not avaialable

Richmond, Virginia
Facility: Virginia Commonwealth University/Massey Cancer Center
Investigator: Mark G. Malkin
Contact: Mark G. Malkin Phone: 773-702-9171
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Bellingham, Washington
Facility: PeaceHealth Saint Joseph Medical Center
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 360-715-4133
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Kennewick, Washington
Facility: Kadlec Clinic Hematology and Oncology
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 509-783-4637
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Seattle, Washington
Facility: Virginia Mason Medical Center
Investigator: Craig R. Nichols
Contact: Craig R. Nichols Phone: 206-342-6954
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Vancouver, Washington
Facility: PeaceHealth Southwest Medical Center
Investigator: Alison K. Conlin
Contact: Alison K. Conlin Phone: 360-514-3940
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Morgantown, West Virginia
Facility: West Virginia University Healthcare
Investigator: Aaron P. Provenzano
Contact: Aaron P. Provenzano Phone: 304-293-7374
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La Crosse, Wisconsin
Facility: Gundersen Lutheran Medical Center
Investigator: Collin D. Driscoll
Contact: Collin D. Driscoll Phone: 608-775-2385
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