Clinical Trial Details
Braintumor Website

[Information provided by: ClinicalTrials.gov, which provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.]

NCT00869401 : Dasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
PhasePhase 1/Phase 2
AgesMin: 18 Years Max: N/A
Eligibility
DISEASE CHARACTERISTICS:

- Histologically confirmed glioblastoma multiforme (GBM)

- Grade 4 astrocytoma

- No grade 4 oligoastrocytoma or GBM with oligodendroglial features

- Newly diagnosed disease

- Measurable or evaluable disease by gadolinium MRI or contrast CT scan

- Patients who have had a gross total resection are eligible on the basis of
evaluable disease

- No pleural or pericardial effusion of any grade

- No prior surgery for CNS neoplasms other than surgery related to the current GBM
diagnosis

- If Gliadel wafers are placed at time of primary resection this would be
considered prior therapy and patient would be ineligible

PATIENT CHARACTERISTICS:

- ECOG performance status 0-2

- Absolute neutrophil count (ANC) ? 1,500/mm³

- Platelet count ? 100,000/mm³

- Hemoglobin > 9.0 g/dL

- Total bilirubin ? 1.5 times upper limit of normal (ULN)

- AST ? 2.5 times ULN

- Creatinine ? 1.5 times ULN

- INR ? 1.5

- Not pregnant or nursing

- Negative pregnancy test

- Fertile patients must use effective contraception during and for ? 12 weeks after
completion of study treatment

- No immunocompromised patients (other than that related to the use of corticosteroids)
including patients known to be HIV positive and currently receiving antiretroviral
therapy

- Patients known to be HIV positive, but without clinical evidence of an
immunocompromised state, are eligible for this trial

- No uncontrolled intercurrent illness including, but not limited to, ongoing or active
infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac
arrhythmia, or psychiatric illness/social situations that would limit compliance with
study requirements

- No history of any of the following conditions:

- Congestive heart failure requiring use of ongoing maintenance therapy for
life-threatening ventricular arrhythmias

- Congenital long QT syndrome

- Clinically significant ventricular arrhythmias (e.g., ventricular tachycardia,
ventricular fibrillation, or Torsades de pointes)

- Prolonged QTc interval on pre-entry electrocardiogram (> 450 msec)

- Hypokalemia or hypomagnesemia

- Patients may not have any clinically significant cardiovascular disease including the
following:

- Myocardial infarction or ventricular tachyarrhythmia within 6 months

- Ejection fraction less than institutional normal

- Major conduction abnormality (unless a cardiac pacemaker is present)

- New York Heart Association classification ? class II congestive heart failure

- Patients with any cardiopulmonary symptoms of unknown cause (e.g., shortness of
breath, chest pain, etc.) should be evaluated by a baseline echocardiogram with
or without stress test as needed in addition to electrocardiogram (ECG) to rule
out QTc prolongation

- Patients with underlying cardiopulmonary dysfunction should be excluded
from the study

- No comorbid systemic illnesses or other severe concurrent disease that, in the
judgment of the investigator, would make the patient inappropriate for entry into
this study or interfere significantly with the proper assessment of safety and
toxicity of the prescribed regimens including, but not limited to, any of the
following:

- History of bleeding diathesis

- Concurrent chronic systemic anticoagulation therapy that can not be discontinued
(i.e., antiplatelet agents or aspirin)

- Concurrent t chronic nonsteroidal anti-inflammatory drugs (NSAIDs) that cannot
be discontinued

- No other active malignancy ? 5 years prior to registration

- Exceptions: Non-melanotic skin cancer or carcinoma-in-situ of the cervix

- If there is a history of prior malignancy, they must not be receiving other
specific treatment (other than hormonal therapy) for their cancer

- No severe allergy to sulfa medications and dapsone

- Able to tolerate either intravenous or inhaled dapsone

- Able to take oral medication

- Willingness to abstain from eating grapefruit or drinking grapefruit juice for the
duration of the study treatment

PRIOR CONCURRENT THERAPY:

- See Disease Characteristics

- See Patient Characteristics

- At least 5 days since prior and no concurrent St. John wort

- No prior radiotherapy or chemotherapy for any CNS neoplasm (hormones, vitamins, and
growth factors are not considered chemotherapy for the purposes of this study)

- At least 7 days, but < 42 days, since prior stereotactic biopsy

- At least 14 days, but < 42 days, since prior open craniotomy

- Willing to forego other cytotoxic and non-cytotoxic drug therapy against the tumor
while being treated with dasatinib and temozolomide

- No other concurrent investigational agent considered as treatment for the primary
neoplasm

- Must not be currently taking any of the following medications:

- Enzyme-inducing anticonvulsants (EIACs)

- To be eligible, patient must be switched to non-EIAC medications ? 7 days
prior to registration

- Potent inhibitors of CYP3A4 that cannot be discontinued

- Medications that may possibly prolong QT interval and produce a QTc that is ? 60
msec or a QTcF that is ? 450 msec

- H2 blockers or proton pump inhibitors (PPIs), such as famotidine (Pepcid) and
omeprazole (Prilosec) respectively, that cannot be discontinued or switched to
locally acting agents, such as Maalox, Mylanta, or TUMS

- No concurrent treatment immunosuppressive agent, except corticosteroids

- No concurrent other anticancer agents

- No concurrent prophylactic leukocyte growth factors (e.g., filgrastim [G-CSF] and
sargramostim [GM-CSF])

- No concurrent live vaccines

- No concurrent therapeutic anticoagulation with warfarin

- No concurrent ibuprofen or other nonsteroidal anti-inflammatory drugs (NSAIDs)
LinksPermanent Link to THIS page: http://virtualtrials.com/nct/display1trial.cfm?nct=NCT00869401      |      Link to official Clinicaltrials.gov listing
Locations
Hartford, Connecticut
Facility: Helen and Harry Gray Cancer Center at Hartford Hospital
Investigator:
Contact: Clinical Trials Office - Helen and Harry Gray Cancer Center Phone: 860-545-5363
Email not avaialable

Jacksonville, Florida
Facility: Mayo Clinic - Jacksonville
Investigator:
Contact: Clinical Trials Office - All Mayo Clinic Locations Phone: 507-538-7623
Email not avaialable

Columbus, Georgia
Facility: John B. Amos Cancer Center
Investigator:
Contact: Clinical Trials Office - John B. Amos Cancer Center Phone: 706-660-6404
Email not avaialable

Bloomington, Illinois
Facility: St. Joseph Medical Center
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-662-3311
Email not avaialable

Bloomington, Illinois
Facility: Illinois CancerCare - Bloomington
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-662-2102
Email not avaialable

Canton, Illinois
Facility: Illinois CancerCare - Canton
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-647-5240
Email not avaialable

Carthage, Illinois
Facility: Illinois CancerCare - Carthage
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 217-357-6877
Email not avaialable

Chicago, Illinois
Facility: Resurrection Medical Center
Investigator:
Contact: Christopher G. Rose, MD Phone: 847-965-3200
Email not avaialable

Eureka, Illinois
Facility: Illinois CancerCare - Eureka
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-467-2371
Email not avaialable

Eureka, Illinois
Facility: Eureka Community Hospital
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-467-2371
Email not avaialable

Galesburg, Illinois
Facility: Galesburg Clinic, PC
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-344-1000
Email not avaialable

Havana, Illinois
Facility: Illinois CancerCare - Havana
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-543-8557
Email not avaialable

Kewanee, Illinois
Facility: Illinois CancerCare - Kewanee Clinic
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-852-0598
Email not avaialable

Macomb, Illinois
Facility: Illinois CancerCare - Macomb
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-833-3503
Email not avaialable

Monmouth, Illinois
Facility: OSF Holy Family Medical Center
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-734-3141
Email not avaialable

Monmouth, Illinois
Facility: Illinois CancerCare - Monmouth
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-734-3141
Email not avaialable

Normal, Illinois
Facility: Illinois CancerCare - Community Cancer Center
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-662-2102
Email not avaialable

Normal, Illinois
Facility: BroMenn Regional Medical Center
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-454-1400
Email not avaialable

Normal, Illinois
Facility: Community Cancer Center
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-451-8500
Email not avaialable

Ottawa, Illinois
Facility: Community Hospital of Ottawa
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 815-433-3100
Email not avaialable

Ottawa, Illinois
Facility: Oncology Hematology Associates of Central Illinois, PC - Ottawa
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 815-431-9270
Email not avaialable

Pekin, Illinois
Facility: Cancer Treatment Center at Pekin Hospital
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-353-0512
Email not avaialable

Pekin, Illinois
Facility: Illinois CancerCare - Pekin
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-353-0214
Email not avaialable

Peoria, Illinois
Facility: Methodist Medical Center of Illinois
Investigator:
Contact: Clinical Trials Office - Methodist Medical Center of Illinois Phone: 309-243-3000
Email not avaialable

Peoria, Illinois
Facility: Proctor Hospital
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-691-1000
Email not avaialable

Peoria, Illinois
Facility: CCOP - Illinois Oncology Research Association
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-243-3605
Email not avaialable

Peoria, Illinois
Facility: OSF St. Francis Medical Center
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-655-2000
Email not avaialable

Peoria, Illinois
Facility: Oncology Hematology Associates of Central Illinois, PC - Peoria
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 309-243-3000
Email not avaialable

Peru, Illinois
Facility: Illinois CancerCare - Peru
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 815-780-3185
Email not avaialable

Peru, Illinois
Facility: Illinois Valley Community Hospital
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 815-223-3000
Email not avaialable

Princeton, Illinois
Facility: Illinois CancerCare - Princeton
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 815-875-3010
Email not avaialable

Spring Valley, Illinois
Facility: Illinois CancerCare - Spring Valley
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 815-664-1487
Email not avaialable

Spring Valley, Illinois
Facility: Valley Cancer Center
Investigator:
Contact: Nguyet A. Le-Lindqwister Phone: 815-664-4141
Email not avaialable

Urbana, Illinois
Facility: CCOP - Carle Cancer Center
Investigator:
Contact: Clinical Trials Office - CCOP - Carle Cancer Center Phone: 800-446-5532
Email not avaialable

Elkhart, Indiana
Facility: Michiana Hematology-Oncology, PC - Elkhart
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

Elkhart, Indiana
Facility: Elkhart General Hospital
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

Elkhart, Indiana
Facility: Elkhart Clinic, LLC
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

Indianapolis, Indiana
Facility: St. Francis Hospital Cancer Care Services
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Kokomo, Indiana
Facility: Howard Community Hospital
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

La Porte, Indiana
Facility: Center for Cancer Therapy at LaPorte Hospital and Health Services
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

Mishawaka, Indiana
Facility: Saint Joseph Regional Medical Center
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

Mishawaka, Indiana
Facility: Michiana Hematology-Oncology, PC - South Bend
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

Plymouth, Indiana
Facility: Michiana Hematology Oncology PC - Plymouth
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

Richmond, Indiana
Facility: Reid Hospital & Health Care Services
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

South Bend, Indiana
Facility: CCOP - Northern Indiana CR Consortium
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

South Bend, Indiana
Facility: Memorial Hospital of South Bend
Investigator:
Contact: Clinical Trials Office - Memorial Hospital of South Bend Phone: 800-284-7370
Email not avaialable

Westville, Indiana
Facility: Michiana Hematology Oncology PC - La Porte
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

Cedar Rapids, Iowa
Facility: Cedar Rapids Oncology Associates
Investigator:
Contact: Clinical Trials Office - Cedar Rapids Oncology Associates Phone: 319-363-2690
Email not avaialable

Cedar Rapids, Iowa
Facility: Mercy Regional Cancer Center at Mercy Medical Center
Investigator:
Contact: Deborah W. Wilbur Phone: 319-398-6011
Email not avaialable

Clive, Iowa
Facility: Medical Oncology and Hematology Associates - West Des Moines
Investigator:
Contact: Robert J. Behrens Phone: 515-875-9713
Email not avaialable

Clive, Iowa
Facility: Mercy Cancer Center - West Lakes
Investigator:
Contact: Robert J. Behrens Phone: 515-643-8206
Email not avaialable

Des Moines, Iowa
Facility: CCOP - Iowa Oncology Research Association
Investigator:
Contact: Robert J. Behrens Phone: 515-244-7586
Email not avaialable

Des Moines, Iowa
Facility: Mercy Cancer Center at Mercy Medical Center - Des Moines
Investigator:
Contact: Robert J. Behrens Phone: 515-643-8206
Email not avaialable

Des Moines, Iowa
Facility: John Stoddard Cancer Center at Iowa Lutheran Hospital
Investigator:
Contact: Clinical Trials Office - John Stoddard Cancer Center at Iowa L Phone: 515-241-8704
Email not avaialable

Des Moines, Iowa
Facility: John Stoddard Cancer Center at Iowa Methodist Medical Center
Investigator:
Contact: Clinical Trials Office - John Stoddard Cancer Center at Iowa M Phone: 515-241-6727
Email not avaialable

Des Moines, Iowa
Facility: Medical Oncology and Hematology Associates at John Stoddard Cancer Center
Investigator:
Contact: Robert J. Behrens Phone: 515-282-2921
Email not avaialable

Des Moines, Iowa
Facility: Medical Oncology and Hematology Associates at Mercy Cancer Center
Investigator:
Contact: Robert J. Behrens Phone: 515-643-8740
Email not avaialable

Sioux City, Iowa
Facility: Mercy Medical Center - Sioux City
Investigator:
Contact: Donald B. Wender, MD, PhD Phone: 712-252-0088
Email not avaialable

Sioux City, Iowa
Facility: St. Luke's Regional Medical Center
Investigator:
Contact: Donald B. Wender, MD, PhD Phone: 712-252-0088
Email not avaialable

Sioux City, Iowa
Facility: Siouxland Hematology-Oncology Associates, LLP
Investigator:
Contact: Donald B. Wender, MD, PhD Phone: 712-252-0088
Email not avaialable

West Des Moines, Iowa
Facility: Methodist West Hospital
Investigator:
Contact: Robert J. Behrens Phone: 515-343-1000
Email not avaialable

Chanute, Kansas
Facility: Cancer Center of Kansas, PA - Chanute
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Dodge City, Kansas
Facility: Cancer Center of Kansas, PA - Dodge City
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

El Dorado, Kansas
Facility: Cancer Center of Kansas, PA - El Dorado
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Fort Scott, Kansas
Facility: Cancer Center of Kansas - Fort Scott
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Independence, Kansas
Facility: Cancer Center of Kansas-Independence
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Kingman, Kansas
Facility: Cancer Center of Kansas, PA - Kingman
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Lawrence, Kansas
Facility: Lawrence Memorial Hospital
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Liberal, Kansas
Facility: Cancer Center of Kansas, PA - Liberal
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Newton, Kansas
Facility: Cancer Center of Kansas, PA - Newton
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Parsons, Kansas
Facility: Cancer Center of Kansas, PA - Parsons
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Pratt, Kansas
Facility: Cancer Center of Kansas, PA - Pratt
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Salina, Kansas
Facility: Cancer Center of Kansas, PA - Salina
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Wellington, Kansas
Facility: Cancer Center of Kansas, PA - Wellington
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Wichita, Kansas
Facility: Cancer Center of Kansas, PA - Wichita
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Wichita, Kansas
Facility: Via Christi Cancer Center at Via Christi Regional Medical Center
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Wichita, Kansas
Facility: Associates in Womens Health, PA - North Review
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Wichita, Kansas
Facility: CCOP - Wichita
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Wichita, Kansas
Facility: Cancer Center of Kansas, PA - Medical Arts Tower
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Wichita, Kansas
Facility: Wesley Medical Center
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Winfield, Kansas
Facility: Cancer Center of Kansas, PA - Winfield
Investigator:
Contact: Shaker R. Dakhil, MD, FACP Phone: 316-262-4467
Email not avaialable

Adrian, Michigan
Facility: Hickman Cancer Center at Bixby Medical Center
Investigator:
Contact: Clinical Trials Office - Hickman Cancer Center at Bixby Medica Phone: 517-265-0116
Email not avaialable

Monroe, Michigan
Facility: Mercy Memorial Hospital - Monroe
Investigator:
Contact: Rex B. Mowat Phone: 734-240-8400
Email not avaialable

Monroe, Michigan
Facility: Community Cancer Center of Monroe
Investigator:
Contact: Rex B. Mowat Phone: 734-242-7902
Email not avaialable

Saint Joseph, Michigan
Facility: Lakeland Regional Cancer Care Center - St. Joseph
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

Saint Joseph, Michigan
Facility: Lakeside Cancer Specialists, PLLC
Investigator:
Contact: Robin Zon, MD Phone: 574-296-6536
Email not avaialable

Bemidji, Minnesota
Facility: MeritCare Bemidji
Investigator:
Contact: Preston D. Steen, MD Phone: 701-234-2397
Email not avaialable

Burnsville, Minnesota
Facility: Fairview Ridges Hospital
Investigator:
Contact: Daniel M. Anderson Phone: 952-892-2000
Email not avaialable

Coon Rapids, Minnesota
Facility: Mercy and Unity Cancer Center at Mercy Hospital
Investigator:
Contact: Daniel M. Anderson Phone: 763-236-6000
Email not avaialable

Duluth, Minnesota
Facility: CCOP - Duluth
Investigator:
Contact: Bret E.B. Friday Phone: 218-786-8364
Email not avaialable

Duluth, Minnesota
Facility: Essentia Health - Duluth Clinic
Investigator:
Contact: Clinical Trials Office - Essentia Health - Duluth Clinic Phone: 218-786-3308
Email not avaialable

Duluth, Minnesota
Facility: Miller - Dwan Medical Center
Investigator:
Contact: Bret E.B. Friday Phone: 218-727-8762
Email not avaialable

Edina, Minnesota
Facility: Fairview Southdale Hospital
Investigator:
Contact: Clinical Trials Office - Fairview Southdale Hospital Phone: 612-625-3650
Email not avaialable

Fridley, Minnesota
Facility: Mercy and Unity Cancer Center at Unity Hospital
Investigator:
Contact: Daniel M. Anderson Phone: 763-236-5000
Email not avaialable

Hutchinson, Minnesota
Facility: Hutchinson Area Health Care
Investigator:
Contact: Daniel M. Anderson Phone: 320-234-5000
Email not avaialable

Maplewood, Minnesota
Facility: HealthEast Cancer Care at St. John's Hospital
Investigator:
Contact: Daniel M. Anderson Phone: 651-232-7970
Email not avaialable

Maplewood, Minnesota
Facility: Minnesota Oncology - Maplewood
Investigator:
Contact: Daniel M. Anderson Phone: 651-779-7978
Email not avaialable

Minneapolis, Minnesota
Facility: Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
Investigator:
Contact: Clinical Trials Office - Virginia Piper Cancer Institute Phone: 612-863-5654
Email not avaialable

Minneapolis, Minnesota
Facility: Hennepin County Medical Center - Minneapolis
Investigator:
Contact: Clinical Trials Office - Hennepin County Medical Center - Minn Phone: 612-873-5911
Email not avaialable

Robbinsdale, Minnesota
Facility: Humphrey Cancer Center at North Memorial Outpatient Center
Investigator:
Contact: Clinical Trials Office - Humphrey Cancer Center at North Memor Phone: 763-520-1893
Email not avaialable

Rochester, Minnesota
Facility: Mayo Clinic Cancer Center
Investigator:
Contact: Clinical Trials Office - All Mayo Clinic Locations Phone: 507-538-7623
Email not avaialable

Saint Cloud, Minnesota
Facility: Coborn Cancer Center
Investigator:
Contact: Donald J. Jurgens Phone: 320-229-4907
Email not avaialable

Saint Cloud, Minnesota
Facility: CentraCare Clinic - River Campus
Investigator:
Contact: Donald J. Jurgens Phone: 320-252-5131
Email not avaialable

Saint Louis Park, Minnesota
Facility: CCOP - Metro-Minnesota
Investigator:
Contact: Daniel M. Anderson Phone: 952-993-1517
Email not avaialable

Saint Louis Park, Minnesota
Facility: Park Nicollet Cancer Center
Investigator:
Contact: Daniel M. Anderson Phone: 952-993-3248
Email not avaialable

Saint Paul, Minnesota
Facility: United Hospital
Investigator:
Contact: Daniel M. Anderson Phone: 651-241-8000
Email not avaialable

Shakopee, Minnesota
Facility: St. Francis Cancer Center at St. Francis Medical Center
Investigator:
Contact: Daniel M. Anderson Phone: 952-403-2031
Email not avaialable

St. Paul, Minnesota
Facility: Regions Hospital Cancer Care Center
Investigator:
Contact: Clinical Trials Office - Regions Hospital Cancer Care Center Phone: 651-254-1517
Email not avaialable

Stillwater, Minnesota
Facility: Lakeview Hospital
Investigator:
Contact: Daniel M. Anderson Phone: 651-439-5330
Email not avaialable

Waconia, Minnesota
Facility: Ridgeview Medical Center
Investigator:
Contact: Daniel M. Anderson Phone: 952-442-2191
Email not avaialable

Willmar, Minnesota
Facility: Willmar Cancer Center at Rice Memorial Hospital
Investigator:
Contact: Daniel M. Anderson Phone: 320-231-4650
Email not avaialable

Woodbury, Minnesota
Facility: Minnesota Oncology - Woodbury
Investigator:
Contact: Daniel M. Anderson Phone: 651-735-7414
Email not avaialable

Saint Louis, Missouri
Facility: Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
Investigator:
Contact: David D. Tran Phone: 314-747-7222
Email not avaialable

Billings, Montana
Facility: St. Vincent Healthcare Cancer Care Services
Investigator:
Contact: Benjamin T. Marchello, MD Phone: 406-238-6290
Email not avaialable

Billings, Montana
Facility: Hematology-Oncology Centers of the Northern Rockies - Billings
Investigator:
Contact: Benjamin T. Marchello, MD Phone: 406-238-6290
Email not avaialable

Billings, Montana
Facility: Billings Clinic - Downtown
Investigator:
Contact: Clinical Trials Office - Billings Clinic - Downtown Phone: 800-996-2663
Click HERE to send email to this center

Billings, Montana
Facility: CCOP - Montana Cancer Consortium
Investigator:
Contact: Benjamin T. Marchello, MD Phone: 406-238-6290
Email not avaialable

Bozeman, Montana
Facility: Bozeman Deaconess Cancer Center
Investigator:
Contact: Benjamin T. Marchello, MD Phone: 406-238-6290
Email not avaialable

Butte, Montana
Facility: St. James Healthcare Cancer Care
Investigator:
Contact: Benjamin T. Marchello, MD Phone: 406-238-6290
Email not avaialable

Great Falls, Montana
Facility: Benefis Sletten Cancer Institute
Investigator:
Contact: Benjamin T. Marchello, MD Phone: 406-238-6290
Email not avaialable

Helena, Montana
Facility: St. Peter's Hospital
Investigator:
Contact: Benjamin T. Marchello, MD Phone: 406-238-6290
Email not avaialable

Kalispell, Montana
Facility: Kalispell Regional Medical Center
Investigator:
Contact: Benjamin T. Marchello, MD Phone: 406-238-6290
Email not avaialable

Missoula, Montana
Facility: Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
Investigator:
Contact: Clinical Trials Office - Montana Cancer Center at St. Patrick Phone: 406-329-7029
Email not avaialable

Missoula, Montana
Facility: Montana Cancer Specialists at Montana Cancer Center
Investigator:
Contact: Clinical Trials Office - Montana Cancer Specialists at Montana Phone: 406-238-6962
Email not avaialable

Concord, New Hampshire
Facility: New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
Investigator:
Contact: Douglas J. Weckstein, MD Phone: 603-622-6484
Email not avaialable

Hooksett, New Hampshire
Facility: New Hampshire Oncology - Hematology, PA - Hooksett
Investigator:
Contact: Douglas J. Weckstein, MD Phone: 603-622-6484
Email not avaialable

Laconia, New Hampshire
Facility: Lakes Region General Hospital
Investigator:
Contact: Douglas J. Weckstein, MD Phone: 603-622-6484
Email not avaialable

Albuquerque, New Mexico
Facility: University of New Mexico Cancer Center
Investigator:
Contact: Clinical Trials Office - University of New Mexico Cancer Cente Phone: 505-272-6972
Email not avaialable

East Syracuse, New York
Facility: CCOP - Hematology-Oncology Associates of Central New York
Investigator:
Contact: Jeffrey J. Kirshner, MD Phone: 315-472-7504
Email not avaialable

Asheville, North Carolina
Facility: Mission Hospitals - Memorial Campus
Investigator:
Contact: Clinical Trials Office - Mission Hospitals - Memorial Campus Phone: 828-213-4150
Email not avaialable

Goldsboro, North Carolina
Facility: Wayne Memorial Hospital, Incorporated
Investigator:
Contact: James N. Atkins, MD Phone: 919-580-0000
Email not avaialable

Bismarck, North Dakota
Facility: Medcenter One Hospital Cancer Care Center
Investigator:
Contact: John T. Reynolds Phone: 701-323-5741
Email not avaialable

Bismarck, North Dakota
Facility: Mid Dakota Clinic, PC
Investigator:
Contact: Clinical Trials Office - Mid Dakota Clinic, PC Phone: 701-530-6950
Email not avaialable

Bismarck, North Dakota
Facility: St. Alexius Medical Center Cancer Center
Investigator:
Contact: Clinical Trials Office - St. Alexius Medical Center Cancer Cen Phone: 701-530-6950
Email not avaialable

Fargo, North Dakota
Facility: MeritCare Broadway
Investigator:
Contact: Preston D. Steen, MD Phone: 701-234-2397
Email not avaialable

Grand Forks, North Dakota
Facility: Altru Cancer Center at Altru Hospital
Investigator:
Contact: Clinical Trails Office - Altru Cancer Center at Altru Hospital Phone: 701-780-6520
Email not avaialable

Bowling Green, Ohio
Facility: Wood County Oncology Center
Investigator:
Contact: Rex B. Mowat Phone: 419-352-9498
Email not avaialable

Chillicothe, Ohio
Facility: Adena Regional Medical Center
Investigator:
Contact: Clinical Trials Office - Adena Regional Medical Center Phone: 877-779-7585
Email not avaialable

Cincinnati, Ohio
Facility: Charles M. Barrett Cancer Center at University Hospital
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Columbus, Ohio
Facility: Riverside Methodist Hospital Cancer Care
Investigator:
Contact: Clinical Trials Office - Riverside Methodist Hospital Cancer C Phone: 614-566-4475
Email not avaialable

Columbus, Ohio
Facility: Mount Carmel Health - West Hospital
Investigator:
Contact: J. Philip Kuebler, MD, PhD Phone: 614-442-3130
Email not avaialable

Columbus, Ohio
Facility: Doctors Hospital at Ohio Health
Investigator:
Contact: Clinical Trials Office - Doctors Hospital at Ohio Health Phone: 614-566-3275
Email not avaialable

Columbus, Ohio
Facility: Grant Medical Center Cancer Care
Investigator:
Contact: Clinical Trials Office - Grant Medical Center Cancer Care Phone: 614-566-4475
Email not avaialable

Columbus, Ohio
Facility: CCOP - Columbus
Investigator:
Contact: J. Philip Kuebler, MD, PhD Phone: 614-442-3130
Email not avaialable

Dayton, Ohio
Facility: David L. Rike Cancer Center at Miami Valley Hospital
Investigator:
Contact: Clinical Trials Office - David L. Rike Cancer Center at Miami Phone: 937-208-2079
Email not avaialable

Dayton, Ohio
Facility: CCOP - Dayton
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Dayton, Ohio
Facility: Grandview Hospital
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Dayton, Ohio
Facility: Samaritan North Cancer Care Center
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Dayton, Ohio
Facility: Good Samaritan Hospital
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Delaware, Ohio
Facility: Grady Memorial Hospital
Investigator:
Contact: J. Philip Kuebler, MD, PhD Phone: 614-442-3130
Email not avaialable

Elyria, Ohio
Facility: Community Cancer Center
Investigator:
Contact: Rex B. Mowat Phone: 440-324-0400
Email not avaialable

Elyria, Ohio
Facility: Hematology Oncology Center
Investigator:
Contact: Rex B. Mowat Phone: 440-324-0401
Email not avaialable

Findlay, Ohio
Facility: Blanchard Valley Medical Associates
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Franklin, Ohio
Facility: Middletown Regional Hospital
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Greenville, Ohio
Facility: Wayne Hospital
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Kettering, Ohio
Facility: Charles F. Kettering Memorial Hospital
Investigator:
Contact: Clinical Trials Office - Charles F. Kettering Memorial Hospita Phone: 937-298-3399 ext. 57556
Email not avaialable

Lancaster, Ohio
Facility: Fairfield Medical Center
Investigator:
Contact: J. Philip Kuebler, MD, PhD Phone: 614-442-3130
Email not avaialable

Lima, Ohio
Facility: Lima Memorial Hospital
Investigator:
Contact: Rex B. Mowat Phone: 419-228-3335
Email not avaialable

Marietta, Ohio
Facility: Strecker Cancer Center at Marietta Memorial Hospital
Investigator:
Contact: J. Philip Kuebler, MD, PhD Phone: 614-442-3130
Email not avaialable

Maumee, Ohio
Facility: Northwest Ohio Oncology Center
Investigator:
Contact: Rex B. Mowat Phone: 419-891-5600
Email not avaialable

Mount Vernon, Ohio
Facility: Knox Community Hospital
Investigator:
Contact: J. Philip Kuebler, MD, PhD Phone: 614-442-3130
Email not avaialable

Newark, Ohio
Facility: Licking Memorial Cancer Care Program at Licking Memorial Hospital
Investigator:
Contact: J. Philip Kuebler, MD, PhD Phone: 614-442-3130
Email not avaialable

Oregon, Ohio
Facility: St. Charles Mercy Hospital
Investigator:
Contact: Rex B. Mowat Phone: 419-696-7200
Email not avaialable

Oregon, Ohio
Facility: Toledo Clinic - Oregon
Investigator:
Contact: Rex B. Mowat Phone: 419-691-4235
Email not avaialable

Portsmouth, Ohio
Facility: Southern Ohio Medical Center Cancer Center
Investigator:
Contact: J. Philip Kuebler, MD, PhD Phone: 614-442-3130
Email not avaialable

Springfield, Ohio
Facility: Community Hospital of Springfield and Clark County
Investigator:
Contact: J. Philip Kuebler, MD, PhD Phone: 614-442-3130
Email not avaialable

Sylvania, Ohio
Facility: Flower Hospital Cancer Center
Investigator:
Contact: Clinical Trials Office - Flower Hospital Cancer Center Phone: 419-824-1842
Email not avaialable

Tiffin, Ohio
Facility: Mercy Hospital of Tiffin
Investigator:
Contact: Rex B. Mowat Phone: 419-447-3130
Email not avaialable

Toledo, Ohio
Facility: St. Anne Mercy Hospital
Investigator:
Contact: Rex B. Mowat Phone: 419-407-2663
Email not avaialable

Toledo, Ohio
Facility: St. Vincent Mercy Medical Center
Investigator:
Contact: Rex B. Mowat Phone: 419-251-4515
Email not avaialable

Toledo, Ohio
Facility: Toledo Hospital
Investigator:
Contact: Clinical Trials Office - Toledo Hospital Phone: 419-824-1842
Email not avaialable

Toledo, Ohio
Facility: Medical University of Ohio Cancer Center
Investigator:
Contact: Clinical Trials Office - Medical University of Ohio Cancer Cen Phone: 419-383-6583
Email not avaialable

Toledo, Ohio
Facility: Toledo Clinic, Incorporated - Main Clinic
Investigator:
Contact: Rex B. Mowat Phone: 419-479-5605
Email not avaialable

Troy, Ohio
Facility: UVMC Cancer Care Center at Upper Valley Medical Center
Investigator:
Contact: Clinical Trials Office - UVMC Cancer Care Center at Upper Vall Phone: 937-440-4842
Email not avaialable

Wauseon, Ohio
Facility: Fulton County Health Center
Investigator:
Contact: Clinical Trials Office - Fulton County Health Center Phone: 419-330-2708
Email not avaialable

West Chester, Ohio
Facility: Precision Radiotherapy at University Pointe
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Westerville, Ohio
Facility: Mount Carmel St. Ann's Cancer Center
Investigator:
Contact: J. Philip Kuebler, MD, PhD Phone: 614-442-3130
Email not avaialable

Xenia, Ohio
Facility: Ruth G. McMillan Cancer Center at Greene Memorial Hospital
Investigator:
Contact: Howard M. Gross, MD Phone: 937-832-1093
Email not avaialable

Zanesville, Ohio
Facility: Genesis - Good Samaritan Hospital
Investigator:
Contact: Clinical Trials Office - Genesis - Good Samaritan Hospital Phone: 740-454-5232
Email not avaialable

Tulsa, Oklahoma
Facility: Natalie Warren Bryant Cancer Center at St. Francis Hospital
Investigator:
Contact: Alan M. Keller Phone: 918-494-2273
Email not avaialable

Allentown, Pennsylvania
Facility: Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
Investigator:
Contact: Suresh G. Nair, MD Phone: 610-402-0512
Email not avaialable

Easley, South Carolina
Facility: Cancer Centers of the Carolinas - Easley
Investigator:
Contact: Clinical Trials Office - Cancer Centers of the Carolinas Phone: 864-241-6251
Email not avaialable

Greenville, South Carolina
Facility: Cancer Centers of the Carolinas - Eastside
Investigator:
Contact: Clinical Trials Office - Cancer Centers of the Carolinas Phone: 864-241-6251
Email not avaialable

Greenville, South Carolina
Facility: Cancer Centers of the Carolinas - Faris Road
Investigator:
Contact: David L. Grisell Phone: 864-679-3900
Email not avaialable

Greenville, South Carolina
Facility: Cancer Centers of the Carolinas - Grove Commons
Investigator:
Contact: Clinical Trials Office - Cancer Centers of the Carolinas Phone: 864-241-6251
Email not avaialable

Greenville, South Carolina
Facility: CCOP - Greenville
Investigator:
Contact: David L. Grisell Phone: 864-241-6251
Email not avaialable

Greenville, South Carolina
Facility: Greenville Hospital Cancer Center
Investigator:
Contact: Clinical Trials Office - Greenville Hospital Cancer Center Phone: 864-241-6251
Email not avaialable

Greer, South Carolina
Facility: Cancer Centers of the Carolinas - Greer Radiation Oncology
Investigator:
Contact: David L. Grisell Phone: 864-334-4900
Email not avaialable

Greer, South Carolina
Facility: Cancer Centers of the Carolinas - Greer Medical Oncology
Investigator:
Contact: David L. Grisell Phone: 864-662-4000
Email not avaialable

Seneca, South Carolina
Facility: Cancer Centers of the Carolinas - Seneca
Investigator:
Contact: David L. Grisell Phone: 864-888-3717
Email not avaialable

Spartanburg, South Carolina
Facility: Cancer Centers of the Carolinas - Spartanburg
Investigator:
Contact: David L. Grisell Phone: 864-699-5700
Email not avaialable

Rapid City, South Dakota
Facility: Rapid City Regional Hospital
Investigator:
Contact: Richard C. Tenglin Phone: 605-719-2360
Email not avaialable

Sioux Falls, South Dakota
Facility: Avera Cancer Institute
Investigator:
Contact: Addison R. Tolentino Phone: 605-322-3000
Email not avaialable

Sioux Falls, South Dakota
Facility: Sanford Cancer Center at Sanford USD Medical Center
Investigator:
Contact: Clinical Trials Office - Sanford Cancer Center Phone: 605-328-1367
Email not avaialable

Fredericksburg, Virginia
Facility: Fredericksburg Oncology, Incorporated
Investigator:
Contact: Rex B. Mowat Phone: 540-368-0500
Email not avaialable

Eau Claire, Wisconsin
Facility: Center for Cancer Treatment & Prevention at Sacred Heart Hospital
Investigator:
Contact: Benjamin E. Lawler Phone: 715-389-3133
Email not avaialable

Eau Claire, Wisconsin
Facility: Marshfield Clinic Cancer Care at Regional Cancer Center
Investigator:
Contact: Benjamin E. Lawler Phone: 715-389-3133
Email not avaialable

Fond du Lac, Wisconsin
Facility: Central Wisconsin Cancer Program at Agnesian HealthCare
Investigator:
Contact: Clinical Trials Office - Central Wisconsin Cancer Program at A Phone: 800-494-2927
Email not avaialable

La Crosse, Wisconsin
Facility: Gundersen Lutheran Center for Cancer and Blood
Investigator:
Contact: Clinical Trials Office - Gundersen Lutheran Cancer Center Phone: 608-775-2385
Click HERE to send email to this center

Marshfield, Wisconsin
Facility: Marshfield Clinic - Marshfield Center
Investigator:
Contact: Clinical Trials Office - Marshfield Clinic - Marshfield Center Phone: 800-782-1581 ext. 94457
Email not avaialable

Marshfield, Wisconsin
Facility: Saint Joseph's Hospital
Investigator:
Contact: Benjamin E. Lawler Phone: 715-389-3133
Email not avaialable

Minocqua, Wisconsin
Facility: Marshfield Clinic - Lakeland Center
Investigator:
Contact: Benjamin E. Lawler Phone: 715-389-3133
Email not avaialable

Rhinelander, Wisconsin
Facility: Ministry Medical Group at Saint Mary's Hospital
Investigator:
Contact: Benjamin E. Lawler Phone: 715-389-3133
Email not avaialable

Rice Lake, Wisconsin
Facility: Marshfield Clinic - Indianhead Center
Investigator:
Contact: Benjamin E. Lawler Phone: 715-389-3133
Email not avaialable

Stevens Point, Wisconsin
Facility: Saint Michael's Hospital Cancer Center
Investigator:
Contact: Benjamin E. Lawler Phone: 715-389-3133
Email not avaialable

Stevens Point, Wisconsin
Facility: Marshfield Clinic at Saint Michael's Hospital
Investigator:
Contact: Benjamin E. Lawler Phone: 715-389-3133
Email not avaialable

Weston, Wisconsin
Facility: Marshfield Clinic - Weston Center
Investigator:
Contact: Benjamin E. Lawler Phone: 715-389-3133
Email not avaialable




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