Clinical Trials
Braintumor Website

There are 46 trials:
Facility: St. Jude Children's Research Hospital
NCT Trial Name# of Centers

NCT01096368

  Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma
150

NCT00082745

  Study of Late-Occurring Complications in Childhood Cancer Survivors
144

NCT03155620

  Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
87

NCT01602666

  Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors
85

NCT01553149

  Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma
76

NCT03213704

  Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)
64

NCT01381718

  Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor
59

NCT03233204

  Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
57

NCT03213665

  Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)
44

NCT03220035

  Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)
41

NCT00939770

  Crizotinib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma
26

NCT01273090

  Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma
23

NCT01878617

  A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
21

NCT02323880

  Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas
21

NCT02780804

  Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
20

NCT02650401

  Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
19

NCT01922076

  WEE1 Inhibitor AZD1775 and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
17

NCT01734512

  PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
14

NCT01748149

  Vemurafenib in Children With Recurrent/Refractory BRAFV600E-mutant Gliomas
14

NCT00867178

  Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System
14

NCT01239316

  Vismodegib in Treating Younger Patients With Recurrent or Refractory Medulloblastoma
11

NCT01514201

  Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas
11

NCT01975116

  p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors
11

NCT02960230

  H3.3K27M Peptide Vaccine for Children With Newly Diagnosed DIPG and Other Gliomas
11

NCT02717455

  Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma
10

NCT02899715

  Panobinostat in Treating Younger Patients With Progressive Diffuse Intrinsic Pontine Glioma
9

NCT02359565

  Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, or Hypermutated Brain Tumors
9

NCT01503086

  Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy
9

NCT02415153

  Pomalidomide in Treating Younger Patients With Recurrent, Progressive or Refractory Central Nervous System Tumors
7

NCT00883688

  Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma
6

NCT00602667

  Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma
6

NCT00899834

  DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma
3

NCT01419067

  A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection
2

NCT01447810

  Constraint-Induced Movement Therapy in a Pediatric Oncology Population
1

NCT01540175

  Immune Reconstitution in Oncology Patients Following Autologous Stem Cell Transplant
1

NCT01393912

  PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma
1

NCT01217996

  Computerized Intervention for Amelioration of Cognitive Late Effects Among Childhood Cancer Survivors
1

NCT00897286

  Study of Stored Tumor Samples in Young Patients With Brain Tumors
1

NCT00085202

  Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor
1

NCT02125786

  A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma
1

NCT02792582

  A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection
1

NCT01498783

  Phase I Study of 5-Fluorouracil in Children and Young Adults With Recurrent Ependymoma
1

NCT01644773

  Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)
1

NCT03194906

  Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Low Grade Glioma
1

NCT03361033

  Components of Social Functioning in Survivors of Pediatric Brain Tumors
1

NCT03434262

  SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors
1



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