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- Last updated refers to the date when our listing for each treatment was last updated.
- ID is our internal ID - starting with VT.
- Min Karnofsky is a general guide to how well you have to function to use this treatment
- For trials that also have a NCT number, you can click that number to pop up the listing from the clinicaltrials.gov website.
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Treatment Name: |
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Intraoperative MRI for brain tumors |
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Keywords: |
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Intra-op MRI |
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Phase: |
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Other / Approved |
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Treatment ID#s: |
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VT396
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Age Group: |
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Adult And Pediatric |
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Min Karnofsky Score: |
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Not Specified |
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Conditions: |
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Newly Diagnosed: Y
Recurrent: Y
Prior Surgery is Allowed
Prior Radiation is Allowed
Prior Chemotherapy is Allowed
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Last Updated: |
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11/20/2005 |
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Tumor Types: |
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Acoustic Neuroma
Anaplastic Astrocytoma
Any Malignant Brain Tumor
Brainstem Glioma
Ependyoma
Germ Cell Tumors
Glioblastoma Multiforme
Gliosarcoma
Hemangioblastoma
Low Grade Glioma
Lymphomas
Medulloblastoma
Meningioma
Metastatic Brain Tumor
Oligodendroglioma High Grade
Optic Glioma
Pediatric Brain Tumors
Pineal Gland Tumor
Pituitary Tumors
PNET Tumor
Recurrent Malignant Pediatric Brain Tumors |
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Comments: |
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Being able to establish the margins of a tumor is extremely important, especially for intrinsic tumors such as low-grade gliomas, glioblastomas and anaplastic astrocytomas. Presently all available image guidance techniques involves preoperatively acquired images to carry this out. Recently, Brigham & Women`s Hospital in Boston, in collaboration with general Electric, have developed an intraoperative MRI scanner that allows direct intraoperative evaluation of patients and their tumors. This is an important technology which may radically change the management of such diseases.
The intraoperative MRI is unlike and previous MRI machine. It has a magnetic field between two `donuts` and allows the patient`s head or other body part to be placed in this and freely accessed by the surgeon. This in turn allows imaging brain surgery, both for image guidance and for resection of tumor.
Applications that we have found particularly important for these tumors include 1. Low grade gliomas such as all gangliogliomas, astrocytomas and DNTs. 2. Malignant gliomas including anaplastic astrocytomas and glioblastoma multiforme. 3. Recurrent gliomas where the margin of the tumor may not be clearly evident. 4. Radiation necrosis. 5. Metastases. 6. Skull base meningiomas. 7. Pituitary adenomas.
These are all applications for establishing the extent of resection. We have considerable experience with this. Our group now (as of 1/99) has done over 200 craniotomies in this device, as well as 100 stereotactic biopsies and we feel that it is a remarkable improvement on other image guided surgical devices.
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Treatment Type: |
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Surgery. |
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Contact: |
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Brigham & Womans Hospital & Childrens Hospital
Peter M. Black, MD, PHD
Chair,Department of Neurosurgery
Contact: Joanne O`Hara, MA
75 Francis St., PBB-CA-138
Boston, MA 02115
Phone:617-732-6992
Fax: (617)713-3050
Click here to send an email
Website: www.boston-neurosurg.org |
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