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Treatment Name: |
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Phase I/II study of sorafenib with radiation and temozolomide in newly diagnosed glioblastoma or gliosarcoma |
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Keywords: |
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sorafenib, radiation, temozolomide |
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Phase: |
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Phase 1/2 |
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Treatment ID#s: |
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VT1898
2008-0059
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Age Group: |
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Adults Only |
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Min Karnofsky Score: |
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60: Requires occasional assistance but is able to care for most of own needs |
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Conditions: |
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Newly Diagnosed: Y
Recurrent: N
Prior Surgery is Allowed Prior Radiation is Not Allowed Prior Chemotherapy is Sometimes Allowed newly diagnosed glioblastoma or gliosarcoma |
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Last Updated: |
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04/03/2009 |
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Tumor Types: |
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Glioblastoma Multiforme Gliosarcoma |
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Comments: |
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Sorafenib is a multi-functional small molecule inhibitor that targets both the Raf/MAP kinase pathway and VEGF receptors. Study includes tumor tissue analyses for tumor profiling. |
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Treatment Type: |
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Chemotherapy Radiation Immunological, Biological or Targeted Therapy. |
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Contact: |
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MD Anderson Cancer Center Jan Esenwein Program Coordinator, Brain Tumor Program Contact: Jan Esenwein or Marie Woodward 1515 Holcombe Blvd Houston, TX 77030- Phone:(713)745-2264 Fax: (713)794-4999 Click here to send an email Website: www.mdanderson.org/diseases/braincancer/ |
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