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- Last updated refers to the date when our listing for each treatment was last updated.
- ID is our internal ID - starting with VT.
- Min Karnofsky is a general guide to how well you have to function to use this treatment
- For trials that also have a NCT number, you can click that number to pop up the listing from the clinicaltrials.gov website.
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Treatment Name: |
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A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Malignant Glioma
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Keywords: |
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ANG1005 |
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Phase: |
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Phase 1 |
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Treatment ID#s: |
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VT1871
NCT00539344
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Age Group: |
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Adults Only |
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Min Karnofsky Score: |
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Not Specified |
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Conditions: |
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Newly Diagnosed: N
Recurrent: Y
Prior Surgery is Allowed Prior Radiation is Allowed Prior Chemotherapy is Allowed |
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Last Updated: |
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10/09/2008 |
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Tumor Types: |
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Anaplastic Astrocytoma Any Malignant Brain Tumor Glioblastoma Multiforme Gliosarcoma |
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Comments: |
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Taxol is a drug that is effective for many cancers including breast and lung to name two. It works very well at killing brain tumor cells in a dish, but lacks the ability to get across the blood brain barrier to work effectively in patients. This study utilizes a 15 amnio acid peptide which is a ligand for a receptor that actively transports across the blood brain barrier, as well as into certain tumor cells like glioblastoma. The peptide has three molecules of taxol conjugated. |
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Treatment Type: |
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Chemotherapy. |
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Contact: |
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Dana-Farber/Harvard Cancer Center Clinical Trials Office - Dana-Farber/Harvard Cancer Center Dana Farber Cancer Institute Boston, MA 02115 Phone:617-582-8480 Email not available Columbia University Medical Center Steven Rosenfeld, MD Contact: Mary Ann Kral New York, NY 10032 Phone:212-305-7266 Click here to send an email MD Anderson Cancer Center Morris Groves, MD Contact: Teresa Hanna 1400 Holcombe Blvd Houston, TX 77030 Phone:713-563-1603 Click here to send an email Website: www.mdanderson.org/diseases/braincancer/ University of Virginia Health System David Schiff, MD Co-Director, Division of Neuro-Oncology Department of Neurology Box 800432 Charlottesville, VA 22908-0432 Phone:434-982-4415 Fax: 434-982-4467 Click here to send an email Website: www.uvabraintumor.com |
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