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- Last updated refers to the date when our listing for each treatment was last updated.
- ID is our internal ID - starting with VT.
- Min Karnofsky is a general guide to how well you have to function to use this treatment
- For trials that also have a NCT number, you can click that number to pop up the listing from the clinicaltrials.gov website.
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Treatment Name: |
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Phase I Trial of Aflibercept (VEGF Trap)with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients With Malignant Gliomas |
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Keywords: |
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Aflibercept (VEGF Trap) |
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Phase: |
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Phase 1/2 |
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Treatment ID#s: |
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VT1815
NABTC 07-01
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Age Group: |
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Adults Only |
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Min Karnofsky Score: |
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60: Requires occasional assistance but is able to care for most of own needs |
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Conditions: |
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Newly Diagnosed: Y
Recurrent: N
Prior Surgery is Allowed
Prior Radiation is Sometimes Allowed
Prior Chemotherapy is Sometimes Allowed
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Last Updated: |
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10/27/2008 |
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Tumor Types: |
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Anaplastic Astrocytoma
Glioblastoma Multiforme
Gliosarcoma
Mixed Glioma
Oligodendroglioma High Grade |
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Comments: |
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VEGF Trap is a specific antagonist that binds and inactivates circulating VEGF in the blood stream and in the extravascular space. Treatment with VEGF Trap is well tolerated and resulted in evaluable response in a significant number of patients when used as a single agent, and constitutes the rationale for combination with temozolomide and radiation therapy following debulking surgery. |
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Treatment Type: |
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Chemotherapy. |
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Contact: |
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UCLA Medical Center
Timothy Cloughesy, MD
Director, Neuro-Oncology Program
710 Westwood Plaza
Reed Bldg, Room 1-230
Los Angeles, CA 90095
Phone:310-825-5321
Fax: (310)825-0644
Click here to send an email
Website: www.neurooncology.ucla.edu
U. Of California At San Francisco
Susan Chang, MD
Neuro Oncology Service
400 Parnassus Avenue, Rm A808
San Francisco, CA 94143
Phone:415-353-2966
Fax: (415)353-2167
Click here to send an email
Dana-Farber/Harvard Cancer Center
Clinical Trials Office - Dana-Farber/Harvard Cancer Center
Dana Farber Cancer Institute
Boston, MA 02115
Phone:617-582-8480
Email not available
The Brain Tumor Center at Duke
David Reardon, MD
Rm 047 Baker House, Hospital South
Trent Drive
Durham, NC 27710
Phone:(919)684-5301
Fax: (919)684-6674
Click here to send an email
Website: www.cancer.duke.edu/btc
Memorial Sloan-Kettering Cancer Center
Lisa Marie DeAngelis, MD
New York, NY 10021
Phone:212-639-7123
Email not available
Hillman Cancer Center
Clinical Trials Office - Hillman Cancer Center
U. of Pittsburgh Cancer Institute
Pittsburgh, PA 15232
Phone:412-647-8073
Email not available
MD Anderson Cancer Center
Jan Esenwein
Program Coordinator, Brain Tumor Program
Contact: Jan Esenwein or Marie Woodward
1515 Holcombe Blvd
Houston, TX 77030-
Phone:(713)745-2264
Fax: (713)794-4999
Click here to send an email
Website: www.mdanderson.org/diseases/braincancer/
University of Texas Health Science Center at San Antonio
John G. Kuhn, Pharm, FCCP
San Antonio, TX 78284-6220
Phone:210-567-8355
Email not available
U. Of Wisconsin Medical School
Minesh Mehta, MD
Professor and Chairman
600 Highland Ave, K4/310-3684
Madison, WI 53972
Phone:608-263-5009
Fax: (608)262-6256
Click here to send an email
Website: www.humonc.wisc.edu |
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