Details For Selected Brain Tumor Treatment

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Last updated refers to the date when our listing for each treatment was last updated.
ID is our internal ID - starting with VT.
Min Karnofsky is a general guide to how well you have to function to use this treatment
For trials that also have a NCT number, you can click that number to pop up the listing from the clinicaltrials.gov website.

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		Treatment Name:		Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer

		Keywords:		Temodar, Erlotinib, Radiation

		Phase:		Phase 3

		Treatment ID#s:		VT1604 NCT00096265

		Age Group:		Adults Only

		Min Karnofsky Score:		70: Cares for self, unable to perform normal activity or to do active work

		Conditions:		Newly Diagnosed: Y Recurrent: Y Prior Surgery is Allowed Prior Radiation is Sometimes Allowed Prior Chemotherapy is Allowed Histologically confirmed non-small cell lung cancer One to 3 intraparenchymal brain metastases by contrast-enhanced MRI, meeting the following criteria: Well circumscribed tumor(s) Maximum diameter = 4.0 cm If multiple lesions are present and one lesion is at the maximum diameter, the other lesions must be = 3.0 cm in maximum diameter No metastases within 10 mm of the optic apparatus such that a portion of the optic nerve or chiasm would be included in the high-dose stereotactic radiosurgery boost field No metastases in the brainstem, midbrain, pons, or medulla No prior complete resection of all known brain metastases Subtotal resection allowed provided residual disease is = 4.0 cm in maximum diameter No clinical or radiographic evidence of progression (other than study lesion[s]) within the past month Patients with brain metastases at initial presentation do not require 1 month of scans documenting stable disease Stable extracranial metastases allowed Extent of extracranial metastases documented by contrast-enhancing CT scans of the chest, abdomen, and pelvis AND bone scan No liver metastases No leptomeningeal metastases by MRI or cerebrospinal fluid evaluation

		Last Updated:		05/01/2007

		Tumor Types:		Metastatic Brain Tumor


		Comments:

		Treatment Type:		Chemotherapy Radiation.

		Contact:		Foundation for Cancer Research and Education David G. Brachman, MD Phoenix, AZ 85013 Phone:602-274-4484 Email not available Christiana Care Health Services Adam Raben, MD Newark, DE 19718 Phone:302-733-6227 Email not available M.D. Anderson Cancer Center - Orlando, Alan R. Forbes, MD, PhD Orlando, FL Phone:407-648-3800 Email not available John B. Amos Community Cancer Center Douglas F. Ciuba, MD Columbus, GA 31904 Phone:706-571-1050 Email not available Wendt Regional Cancer Center at Finley Hospital James R. Baer, MD Dubuque, IA 52001 Phone:563-589-2468 Email not available Saint Alphonsus Cancer Care Center Timothy E. Sawyer, MD Saint Alphonsus Regional Medical Center Boise, ID Phone:208-367-7954 Email not available Ingalls Cancer Care Center Robert E. Share, MD Ingalls Memorial Hospital Harvey, IL 60426 Phone:708-915-6620 Email not available Oncology Center at St. Margaret Mercy Healthcare Center, Urmi P. Kalokhe, MD Hammond, IN 46320 Phone:219-933-2130 Email not available Borgess Medical Center Raymond S. Lord, MD Kalamazoo, MI 49007 Phone:269-373-7488 Email not available CCOP - Metro-Minnesota Patrick J. Flynn, MD Saint Louis Park, MN 55416 Phone:612-863-8585 Email not available Southern Nevada Cancer Research Foundation John A. Ellerton, MD Las Vegas, NV 89106 Phone:702-384-0013 Email not available Harvey Cushing Brain Tumor Institute at North Shore University Hospital John DelRowe, MD 300 Community Drive, 9 Tower Manhasset, NY 11030 Phone:516-562-4815 Email not available Akron City Hospital at Summa Health System William F. Demas, MD Akron, OH 44304 Phone:330-375-3557 Email not available Cleveland Clinic Brain Tumor and Neuro-Oncology Center John Suh, MD Contact: Renee Yorkievitz 9500 Euclid Ave Cleveland, OH 44195 Phone:216-445-6545 Click here to send an email Kimmel Cancer Center Maria Werner-Wasik, MD Thomas Jefferson University - Philadelphia Philadelphia, PA 19107 Phone:215-955-7679 Email not available LDS Hospital William T. Sause, MD Salt Lake City, UT 84143 Phone:801-408-1146 Email not available Massey Cancer Center Michael P. Hagan, MD Virginia Commonwealth University Clinical Trials Office - Masse Richmond, VA 23298 Phone: Email not available Medical College of Wisconsin Cancer Center Elizabeth M. Gore,, MD Milwaukee, WI 53226 Phone:414-805-4465 Email not available

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