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- Last updated refers to the date when our listing for each treatment was last updated.
- ID is our internal ID - starting with VT.
- Min Karnofsky is a general guide to how well you have to function to use this treatment
- For trials that also have a NCT number, you can click that number to pop up the listing from the clinicaltrials.gov website.
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Treatment Name: |
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A Phase II Study of a Temozolomide-Based Chemoradiotherapy Regimen for High-Risk Low-Grade Gliomas |
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Keywords: |
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Temodar, radiation |
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Phase: |
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Phase 2 |
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Treatment ID#s: |
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VT1580
NCT00114140
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Age Group: |
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Adults Only |
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Min Karnofsky Score: |
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60: Requires occasional assistance but is able to care for most of own needs |
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Conditions: |
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Newly Diagnosed: Y
Recurrent: N
Prior Surgery is Allowed Prior Radiation is Not Allowed Prior Chemotherapy is Not Allowed Must have = 3 of the following risk factors:
Age 40 and over
Largest preoperative tumor diameter = 6 cm
Tumor crosses the midline
Astrocytoma-dominant tumor subtype
Preoperative Neurological Function Status > 1
No other low-grade glioma histologies, including any of the following:
Pilocytic astrocytoma
Subependymal giant cell astrocytoma of tuberous sclerosis
Subependymoma
Pleomorphic xanthoastrocytoma
Presence of a neuronal element, such as ganglioglioma
Dysneuroembryoplastic epithelial tumor
No high-grade glioma, including any of the following:
Anaplastic astrocytoma
Glioblastoma multiforme
Anaplastic oligodendroglioma
Anaplastic oligoastrocytoma
No tumors in any nonsupratentorial location, including any of the following:
Optic chiasm
Optic nerve(s)
Pons
Medulla
Cerebellum
Spinal cord
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Last Updated: |
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05/01/2007 |
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Tumor Types: |
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Anaplastic Astrocytoma Low Grade Glioma Oligodendroglioma Low Grade |
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Comments: |
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Treatment Type: |
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Chemotherapy Radiation. |
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Contact: |
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Foundation for Cancer Research and Education David G. Brachman, MD Phoenix, AZ 85013 Phone:602-274-4484 Email not available Yale University School Of Medicine Jonathan P.S. Knisely, MD, FRCPC Contact: Colleen Malone New Haven, CT 06520 Phone:203-785-2960 Click here to send an email Beebe Medical Center Christopher D. Koprowski, MD Lewes, DE 19958 Phone:302-733-6227 Email not available Michael & Dianne Bienes Comprehensive Cancer Center Leonard J. Seigel, MD Holy Cross Hospital Fort Lauderdale, FL 33308 Phone:954-267-7700 Email not available Baptist Cancer Institute - Jacksonville Douglas W. Johnson, MD Jacksonville, FL 32207 Phone:904-202-7020 Email not available Mayo Clinic Cancer Center - FL Toni Kay Mangskau-FL Clinical Trials Referral Coordinator 4500 San Pablo Road Jacksonville, FL 32224 Phone:(507)538-7623 Click here to send an email Website: www.mayoclinic.org/cancer-treatment/ University of Miami Sylvester Comprehensive Cancer Center Arnold M. Markoe, MD, ScD Miami, FL 33136 Phone:305-243-4319 Email not available John B. Amos Community Cancer Center Douglas F. Ciuba, MD Columbus, GA 31904 Phone:706-571-1050 Email not available Wendt Regional Cancer Center at Finley Hospital James R. Baer, MD Dubuque, IA 52001 Phone:563-589-2468 Email not available Henry Ford Hospital Tom MikKelsen, MD, FRCP(C) Co-Director Contact: Dr. Tom Mikelsen Hermelin Brain Tumor Center E&R3096 Henry Ford Hospital 2799 West Grand Blvd Detroit, MI 48202- Phone:313 916-8641 Fax: 313 916-9855 Click here to send an email Website: www.nabtt.org/henry.html Bronson Methodist Hospital Raymond S. Lord, MD Kalamazoo, MI 49007 Phone:269-373-7488 Email not available Haematology-Oncology Associates of Ohio and Michigan, P.C., Paul L. Schaefer, MD Lambertville, MI 48144 Phone:419-843-6147 Email not available Mayo Clinic Cancer Center Paul D. Brown, MD Rochester, MN 55905 Phone:507-284-2511 Email not available Mayo Clinic Cancer Center - MN Toni Kay Mangskau-MN Clinical Trials Referral Coordinator 200 First Street SW Rochester, MN 55905 Phone:(507)538-7623 Click here to send an email Website: www.mayoclinic.org/cancer-treatment/ CCOP - Metro-Minnesota Patrick J. Flynn, MD Saint Louis Park, MN 55416 Phone:612-863-8585 Email not available CCOP - Cancer Research for the Ozarks John Wendall Goodwin, MD Springfield, MO 64131 Phone:417-269-4520 Click here to send an email Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha James A. Reilly, MD Omaha, NB 68114 Phone:402-354-8163 Email not available CCOP - Southeast Cancer Control Consortium James N. Atkins, MD Goldsboro, NC 27534-9479 Phone:919-580-0000 Email not available Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center Eugen B. Hug, MD Lebanon, NH 03756 Phone:603-653-9000 Email not available Monmouth Medical Center Sang E. Sim Long Branch, NJ 07740 Phone:732-923-6890 Email not available Fox Chase Virtua Health Cancer Program - Marlton Lemuel S. Ariaratnam,, MD Mount Holly, NJ 08060 Phone:856-355-6160 Email not available New Mexico Cancer Center Joel H. Elconin Albuquerque, NM 87109 Phone:505-842-8171 Email not available Roswell Park Cancer Institute Michael R. Kuettel, MD, PhD Buffalo, NY 14263 Phone:716-845-1562 Email not available Faxton Regional Cancer Center Faina Sherman Utica, NY 13502 Phone:315-624-4673 Email not available CCOP - Columbus J. Philip Kuebler, MD, PhD , OH 43206 Phone:614-488-2118 Email not available Akron City Hospital at Summa Health System William F. Demas, MD Akron, OH 44304 Phone:330-375-3557 Email not available Cleveland Clinic Brain Tumor and Neuro-Oncology Center John Suh, MD Contact: Renee Yorkievitz 9500 Euclid Ave Cleveland, OH 44195 Phone:216-445-6545 Click here to send an email LaFortune Cancer Center at St. John Health System Diane Heaton, MD Tulsa, OK 74104 Phone:918-744-2071 Email not available CCOP - Columbia River Oncology Program Keith S. Lanier, MD Portland, OR 97225 Phone:503-216-6260 Email not available Albert Einstein Cancer Center Sucha O. Asbell, MD Philadelphia, PA 19141 Phone:215-456-6280 Email not available Thomas Jefferson University Hospital Walter Curran, Jr, MD Contact: Roseann Bonanni Philadelphia, PA Phone:215-955-8619 Click here to send an email CCOP - MainLine Health Paul B. Gilman, MD Wynnewood, PA 19096 Phone:610-645-4400 Email not available CCOP - Greenville Jeffrey Kent Giguere, MD Greenville, SC 29615 Phone:864-241-6251 Email not available Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center Malcolm (Mack) R. Mathews, MD Kingsport, TN 37660 Phone:423-224-3150 Email not available LDS Hospital William T. Sause, MD Salt Lake City, UT 84143 Phone:801-408-1146 Email not available U. Of Wisconsin Medical School Minesh Mehta, MD Professor and Chairman 600 Highland Ave, K4/310-3684 Madison, WI 53972 Phone:608-263-5009 Fax: (608)262-6256 Click here to send an email Website: www.humonc.wisc.edu |
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