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Treatment Name: Reduced Dose Craniospinal Radiation (1800 cGy) and Chemotherapy in children with newly-diagnosed standard-risk posterior fossa primitive neuro-ectodermal tumor (PNET/medulloblastoma )
Phase: Phase 3
Treatment ID#: 804         CHP 693
Age Group: Pediatric Only
Min Karnofsky Score: Not Specified
Conditions: Prior Surgery is Allowed
Prior Radiation is Not Allowed
Prior Chemotherapy is Not Allowed
Age 3 - 21 years at diagnosis Histology Proven Posterior Fossa PNET No metastatic disease Residual tumor volume less than 1.5 cubic centimeters Must begin radiotherapy before 30 days from surgery
Last Updated: 11/26/2005
Tumor Types: Medulloblastoma
PNET Tumor
Comments: Radiation Therapy: 5580 cGy tumor bed, conformal techniques; 1800 cGy craniospinal Concurrent chemotherapy during radiation with vincristine. Maintenance chemotherapy delivered after RT in an AABAABAAB pattern: CCNU, Vincristine, Cisplatinum (Regimen A) Cyclophosphamide, VP-16 (Regimen B)
Treatment Type: Chemotherapy
Radiation
Contact: Anna J. Janss MD, Phd
Winship Cancer Institute
Emory University

Egleston, GA 30322 USA
Phone: 404-257-3480
Fax:
E-mail:
Website:
  • Last updated refers to the date when our listing for each treatment was last updated.
  • ID is a combination of our internal ID and the official ID for the trial, if any.
  • Min Karnofsky is a general guide to how well you have to function to use this treatment



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