Details For Selected Brain Tumor Treatment

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		Treatment Name:		Phase I trial to study the effectiveness of combining paclitaxel with radiation therapy in treating children who have newly diagnosed brain stem glioma.

		Phase:		Phase 1

		Treatment ID#:		787 CHOP-2

		Age Group:		Pediatric Only

		Min Karnofsky Score:		Not Specified

		Conditions:		Prior Surgery is Not Allowed Prior Radiation is Not Allowed Prior Chemotherapy is Not Allowed Newly diagnosed diffuse pontine glioma >3 and < 21 years at diagnosis

		Last Updated:		11/26/2005

		Tumor Types:		Brainstem Glioma


		Comments:		Taxol will be administered as a one-hour IV infusion starting at an initial study dose of 175 mg/m2/day, once a week for a total of six doses during radiation therapy. The dose levels for this study are (175, 200, 225, 250 and +25 thereafter. Cohorts of three patients will be studied at each dose. Patients can chose to receive maintenance Taxol given at the same dose, every 3 weeks for a total of eight additional doses.

		Treatment Type:		Chemotherapy Radiation

		Contact:		Anna J. Janss MD, Phd Winship Cancer Institute Emory University Egleston, GA 30322 USA Phone: 404-257-3480 Fax: E-mail: Website:

Last updated refers to the date when our listing for each treatment was last updated.
ID is a combination of our internal ID and the official ID for the trial, if any.
Min Karnofsky is a general guide to how well you have to function to use this treatment

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