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Treatment Name: Methotrexate, Cyclophosphamide, and Etoposide Phosphate Given With Osmotic Blood-Brain Barrier Disruption Plus Dexamethasone and Cytarabine in Treating Patients With Primary CNS Lymphoma
Phase: Phase 2
Treatment ID#: 716        
Age Group: Adults Only
Min Karnofsky Score: 50: Requires considerable assistance and frequent medical care
Conditions: Prior Surgery is Allowed
Prior Radiation is Not Allowed
Prior Chemotherapy is Allowed
First relapse of NHL in the CNS, No prior radiotherapy to the CNS, No prior bone marrow transplantation
Last Updated: 05/01/2007
Tumor Types: Lymphomas
Metastatic Brain Tumor
Comments: Treatment includes high-dose methotrexate given IV and intra-arterial chemotherapy with carboplatine given inconjunction with blood-brain barrier disruption. After 4 cycles patients in complete response undergo high dose chemotherapy with autologous peripheral stem cell transplantation. No radiotherapy id given to responding patients.
Treatment Type: Chemotherapy
Contact: Dr.Edward Neuwelt M.D.
Professor
Oregon Health Sciences University
3181 SW Sam Jackson Park Rd
L603
Portland, OR 97239 USA
Phone: (503)494-5626
Fax: (503)494-5627
E-mail: neuwelte@ohsu.edu
Website: www.ohsu.edu/bbb
  • Last updated refers to the date when our listing for each treatment was last updated.
  • ID is a combination of our internal ID and the official ID for the trial, if any.
  • Min Karnofsky is a general guide to how well you have to function to use this treatment



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