Details For Selected Brain Tumor Treatment

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		Treatment Name:		Phase I study of Photodynamic Therapy with porfimer sodium for refractory brain tumors

		Phase:		Phase 1

		Treatment ID#:		381 7594

		Age Group:		Adult And Pediatric

		Min Karnofsky Score:		80: Able to perform normal activity with effort; some signs and symptoms of disease

		Conditions:		Prior Surgery is Allowed Prior Radiation is Allowed Prior Chemotherapy is Allowed Primary supratentorial or infratentorial brain tumor of one the following histologies: Astrocytoma Ependymoma Medulloblastoma. Tumor unresectable and progressive or recurrent following standard therapy, including radiotherapy. Nondisseminated disease measurable as a single localized mass on CT or MRI. Negative cerebrospinal fluid required. No prior brachytherapy.

		Last Updated:		11/26/2005

		Tumor Types:		Anaplastic Astrocytoma Brainstem Glioma Ependyoma Glioblastoma Multiforme Medulloblastoma Metastatic Brain Tumor Optic Glioma


		Comments:		Photosensitization followed by Light Therapy plus Surgery (as feasible). DHE (Porfimer Sodium); followed by a KTP-pumped dye laser (wavelength 630 nm) delivered to the tumor using 0.5- to 2.0-cm cylindrical diffusers (200 mW/cm) or to the resection cavity via a balloon catheter (50 mW/sqcm); plus maximum feasible tumor debulking. WARNING:

		Treatment Type:		Surgery

		Contact:		Harry T. Whelan MD Medical College of Wisconsin Cancer Center 8701 Watertown Plank Road Milwaukee, WI USA Phone: 414-456-4090 Fax: (414)456-8538 E-mail: Website:

Last updated refers to the date when our listing for each treatment was last updated.
ID is a combination of our internal ID and the official ID for the trial, if any.
Min Karnofsky is a general guide to how well you have to function to use this treatment

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