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Treatment Name: A Phase 1b Study of AdV-tk + Valacyclovir Gene Therapy in Combination With Standard Radiation Therapy for Malignant Gliomas
Phase: Phase 1
Treatment ID#: 2005        
Age Group: Adults Only
Min Karnofsky Score: 70: Cares for self, unable to perform normal activity or to do active work
Conditions: Prior Surgery is Allowed
Prior Radiation is Not Allowed
Prior Chemotherapy is Not Allowed
The purpose of this study is to determine if the addition of a device called NovoTTF-100A given with standard chemotherapy drug called Temozolomide (Temodar) is more effective than when Temozolomide is given alone. The NovoTTF-100A device is a portable battery operated device which produces Tumor Treating Fields (TTFields) within the human body through surface electrodes. It is believed that with very low intensity, intermediate frequency electric fields (TTFields) will stunt the growth of tumor cells.
Last Updated: 12/20/2010
Tumor Types: Anaplastic Astrocytoma
Glioblastoma Multiforme
Treatment Type: Immunological, Biological or Targeted Therapy
Gene Therapy
Contact: Pamela New MD
Principal Investigator
The Methodist Hospital
Contact: Kimbra Harris, CCRP
6560 Fannin St., Suite 944
Houston, TX 77030 USA
Phone: 713-441-3834
Fax: 713-790-2609
  • Last updated refers to the date when our listing for each treatment was last updated.
  • ID is a combination of our internal ID and the official ID for the trial, if any.
  • Min Karnofsky is a general guide to how well you have to function to use this treatment

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