Details For Selected Brain Tumor Treatment

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		Treatment Name:		A Phase 1b Study of AdV-tk + Valacyclovir Gene Therapy in Combination With Standard Radiation Therapy for Malignant Gliomas

		Phase:		Phase 1

		Treatment ID#:		2005

		Age Group:		Adults Only

		Min Karnofsky Score:		70: Cares for self, unable to perform normal activity or to do active work

		Conditions:		Prior Surgery is Allowed Prior Radiation is Not Allowed Prior Chemotherapy is Not Allowed The purpose of this study is to determine if the addition of a device called NovoTTF-100A given with standard chemotherapy drug called Temozolomide (Temodar) is more effective than when Temozolomide is given alone. The NovoTTF-100A device is a portable battery operated device which produces Tumor Treating Fields (TTFields) within the human body through surface electrodes. It is believed that with very low intensity, intermediate frequency electric fields (TTFields) will stunt the growth of tumor cells.

		Last Updated:		12/20/2010

		Tumor Types:		Anaplastic Astrocytoma Glioblastoma Multiforme


		Comments:

		Treatment Type:		Immunological, Biological or Targeted Therapy Gene Therapy

		Contact:		Pamela New MD Principal Investigator The Methodist Hospital Contact: Kimbra Harris, CCRP 6560 Fannin St., Suite 944 Houston, TX 77030 USA Phone: 713-441-3834 Fax: 713-790-2609 E-mail: ksharris@tmhs.org Website: www.methodisthealth.com

Last updated refers to the date when our listing for each treatment was last updated.
ID is a combination of our internal ID and the official ID for the trial, if any.
Min Karnofsky is a general guide to how well you have to function to use this treatment