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Treatment Name: A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Malignant Glioma
Phase: Phase 1
Treatment ID#: 1871        
Age Group: Adults Only
Min Karnofsky Score: Not Specified
Conditions: Prior Surgery is Allowed
Prior Radiation is Allowed
Prior Chemotherapy is Allowed
Last Updated: 10/09/2008
Tumor Types: Anaplastic Astrocytoma
Any Malignant Brain Tumor
Glioblastoma Multiforme
Gliosarcoma
Comments: Taxol is a drug that is effective for many cancers including breast and lung to name two. It works very well at killing brain tumor cells in a dish, but lacks the ability to get across the blood brain barrier to work effectively in patients. This study utilizes a 15 amnio acid peptide which is a ligand for a receptor that actively transports across the blood brain barrier, as well as into certain tumor cells like glioblastoma. The peptide has three molecules of taxol conjugated.
Treatment Type: Chemotherapy
Contact: David Schiff MD
Co-Director, Division of Neuro-Oncology
University of Virginia Health System
Department of Neurology
Box 800432
Charlottesville, VA 22908-0432 USA
Phone: 434-982-4415
Fax: 434-982-4467
E-mail: ds4jd@virginia.EDU
Website: www.uvabraintumor.com
  • Last updated refers to the date when our listing for each treatment was last updated.
  • ID is a combination of our internal ID and the official ID for the trial, if any.
  • Min Karnofsky is a general guide to how well you have to function to use this treatment



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