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Treatment Name: |
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Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors
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Phase: |
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Phase 1 |
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Treatment ID#: |
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1598 NCT00049023 |
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Age Group: |
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Adult And Pediatric |
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Min Karnofsky Score: |
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70: Cares for self, unable to perform normal activity or to do active work |
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Conditions: |
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Prior Surgery is Allowed Prior Radiation is Allowed Prior Chemotherapy is Allowed Histologically or cytologically confirmed malignant neoplasm
Not amenable to standard therapy or has failed existing first- and second-line therapies
Tumor positive for somatostatin receptors by OctreoScan within the past 4 weeks
At least 1 measurable lesion
Lesions that have been previously irradiated must demonstrate progression since radiation
At least 1 measurable somatostatin receptor-positive lesion that has not been irradiated within the past 4 weeks AND has not had full craniospinal radiation within the past 3 months
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Last Updated: |
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11/06/2005 |
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Tumor Types: |
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Any Malignant Brain Tumor Glioblastoma Multiforme Gliosarcoma Recurrent Malignant Pediatric Brain Tumors |
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Comments: |
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RATIONALE: Radiolabeled octreotide can locate tumor cells and deliver radioactive tumor-killing substances to them without harming normal cells.
PURPOSE: This phase I trial is studying the effectiveness of radiolabeled octreotide in treating children who have advanced or refractory solid tumors.
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Treatment Type: |
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Immunological, Biological or Targeted Therapy |
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Contact: |
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M. Sue O`Dorisio MD, PhD Holden Comprehensive Cancer Center at University of Iowa
Iowa City, IA 52242-1009 USA Phone: 319-356-7873 Fax: E-mail: sue_odorisio@uiowa.edu Website: |
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