Details For Selected Brain Tumor Treatment

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		Treatment Name:		Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

		Phase:		Phase 1

		Treatment ID#:		1593 NCT00107458

		Age Group:		Pediatric Only

		Min Karnofsky Score:		50: Requires considerable assistance and frequent medical care

		Conditions:		Prior Surgery is Allowed Prior Radiation is Allowed Prior Chemotherapy is Allowed Histologically confirmed* solid tumors, including CNS tumors, at original diagnosis or relapse Recurrent or refractory disease NOTE: *Histologic confirmation not required for intrinsic brain stem or optic pathway tumors Measurable or evaluable disease, defined by 1 of the following criteria: Any unidimensionally measurable lesion ≥ 20 mm by standard MRI or CT scan OR ≥ 10 mm by spiral CT scan At least 1 nonmeasurable lesion that is evaluable by nuclear medicine, immunocytochemistry, tumor markers, cerebrospinal fluid cytology, or other reliable measures No known curative therapy exists

		Last Updated:		11/11/2005

		Tumor Types:		Any Malignant Brain Tumor Brainstem Glioma Glioblastoma Multiforme Meningioma Oligodendroglioma High Grade Recurrent Malignant Pediatric Brain Tumors


		Comments:

		Treatment Type:		Chemotherapy

		Contact:		H.S. Nicholson MD, MPH Doernbecher Children`s Hospital at Oregon Health & Science University Portland, OR 97239-3098 USA Phone: 503-494-1543 Fax: E-mail: Website:

Last updated refers to the date when our listing for each treatment was last updated.
ID is a combination of our internal ID and the official ID for the trial, if any.
Min Karnofsky is a general guide to how well you have to function to use this treatment

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