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Treatment Name: |
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Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors |
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Phase: |
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Phase 1 |
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Treatment ID#: |
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1593 NCT00107458 |
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Age Group: |
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Pediatric Only |
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Min Karnofsky Score: |
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50: Requires considerable assistance and frequent medical care |
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Conditions: |
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Prior Surgery is Allowed Prior Radiation is Allowed Prior Chemotherapy is Allowed Histologically confirmed* solid tumors, including CNS tumors, at original diagnosis or relapse
Recurrent or refractory disease NOTE: *Histologic confirmation not required for intrinsic brain stem or optic pathway tumors
Measurable or evaluable disease, defined by 1 of the following criteria:
Any unidimensionally measurable lesion ≥ 20 mm by standard MRI or CT scan OR ≥ 10 mm by spiral CT scan
At least 1 nonmeasurable lesion that is evaluable by nuclear medicine, immunocytochemistry, tumor markers, cerebrospinal fluid cytology, or other reliable measures
No known curative therapy exists
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Last Updated: |
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11/11/2005 |
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Tumor Types: |
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Any Malignant Brain Tumor Brainstem Glioma Glioblastoma Multiforme Meningioma Oligodendroglioma High Grade Recurrent Malignant Pediatric Brain Tumors |
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Comments: |
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Treatment Type: |
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Chemotherapy |
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Contact: |
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Dale Jeanette Pullen MD University of Mississippi Medical Center
Jackson, MS 39216-4505 USA Phone: 601-984-5220 Fax: E-mail: Website: |
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- Last updated refers to the date when our listing for each treatment was last updated.
- ID is a combination of our internal ID and the official ID for the trial, if any.
- Min Karnofsky is a general guide to how well you have to function to use this treatment
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