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Treatment Name: |
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Talampanel, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
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Phase: |
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Phase 2 |
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Treatment ID#: |
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1483 NCT00082992 |
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Age Group: |
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Adults Only |
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Min Karnofsky Score: |
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60: Requires occasional assistance but is able to care for most of own needs |
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Conditions: |
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Prior Surgery is Allowed Prior Radiation is Not Allowed Prior Chemotherapy is Not Allowed |
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Last Updated: |
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04/29/2007 |
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Tumor Types: |
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Glioblastoma Multiforme |
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Comments: |
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Induction therapy: Patients undergo radiotherapy once daily on days 1-5. Beginning on day 1 of radiotherapy, patients receive oral talampanel 3 times daily on days 1-7. Treatment repeats weekly for 6 weeks.
Maintenance therapy: Beginning immediately after the completion of induction therapy, patients receive oral talampanel 3 times daily on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients are followed every 2 months. |
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Treatment Type: |
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Chemotherapy Radiation |
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Contact: |
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Samuel Ryu MD Henry Ford Hospital Contact: Tiffany Pearce
Detroit, MI 48202 USA Phone: 313-916-1784 Fax: E-mail: TPEARCE1@hfhs.org Website: |
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