Details For Selected Brain Tumor Treatment

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		Treatment Name:		Phase I/II Trial of Imatinib Mesylate; (Gleevec; ST1571) in Treatment of Recurrent Oligodendroglioma and Mixed Oligoastrocytoma

		Phase:		Phase 1/2

		Treatment ID#:		1347

		Age Group:		Adults Only

		Min Karnofsky Score:		60: Requires occasional assistance but is able to care for most of own needs

		Conditions:		Prior Surgery is Allowed Prior Radiation is Allowed Prior Chemotherapy is Sometimes Allowed Histologically confirmed oligodendroglioma or mixed oligoastrocytoma Grade 2-4 Recurrent disease Failed prior surgery, radiotherapy, nitrosourea-based therapy, or temozolomide chemotherapy regimen Progressive disease by MRI or CT scan No more than 2 prior chemotherapy regimens No prior or concurrent significant intratumoral hemorrhage

		Last Updated:		11/27/2005

		Tumor Types:		Mixed Glioma Oligodendroglioma High Grade Oligodendroglioma Low Grade


		Comments:		No prior interstitial chemotherapy, including carmustine wafers, unless separate lesion seen on MRI outside of prior treatment field

		Treatment Type:		Chemotherapy

		Contact:		Donald Bruce Wender MD, PhD Siouxland Hematology-Oncology Sioux City, IA 51101-1733 USA Phone: 712-252-0088 Fax: E-mail: shoaresearch@shoa-research.org Website:

Last updated refers to the date when our listing for each treatment was last updated.
ID is a combination of our internal ID and the official ID for the trial, if any.
Min Karnofsky is a general guide to how well you have to function to use this treatment

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