Trials and Noteworthy Treatments

			Treatment Next 25		Location		Last Updated
	Details		Gliogene: Brain Tumor Linkage Study		San Francisco, CA Tampa, FL Boston, MA New York, NY Houston, Tx		01/17/2008
	Details		NABTC 04-02: Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma		Los Angeles, CA Boston, MA Durham, NC New York, NY Pittsburgh, PA Houston, TX San Antonio, TX Madison, WI		10/03/2007
	Details		Phase II Study of Gleevec/Imatinib Mesylate (STI-571, NSC 716051) in Neurofibromatosis (NF1) Patients with Plexiform Neurofibromas		Dallas, TX		11/21/2006
	Details		RTA 744 in Treating Patients With Recurrent or Refractory Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Anaplastic Mixed Oligoastrocytoma, Glioblastoma Multiforme, or Gliosarcoma		Los Angeles, CA Dallas, TX		11/21/2006
	Details		PEG-Interferon alfa-2b With or Without Thalidomide in Treating Patients With Recurrent High-Grade Gliomas		Los Angeles, CA Boston, MA Ann Arbor, MI New York, NY Pittsburgh, PA Houston, TX San Antonio, TX Madison, WI		05/04/2006
	Details		Phase 3 study: Radiation Therapy and Combination Chemotherapy Followed by Autologous Stem Cell Transplant in Treating Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor		Durham, NC Memphis, TN Houston, TX		05/02/2006
	Details		A Randomized Phase II Study of Peg-Interferon Alpha-2B (Peg-Intron) Alone or in Combination with Thalidomide in Adults with Recurrent High-Grade Gliomas		Los Angeles, CA Boston, MA Ann Arbor, MI New York, NY Pittsburgh, PA Houston, TX San Antonio, TX Madison, WI		11/27/2005
	Details		Phase 2 Trial of Salvage Chemotherapy with Temozolomide in Combination with Topotecan for Primary CNS Lymphoma.		San Antonio, TX		11/27/2005
	Details		Pilot Study of Systemic and Intrathecal Chemotherapy Followed by Conformal Radiation for Infants with Brain Tumors		Durham, NC Memphis, TN Houston, TX		11/27/2005
	Details		Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme		Houston, TX		11/27/2005
	Details		Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma		Washington, DC Chicago, IL Baltimore, MD Memphis, TN Dallas, TX Houston, TX		11/11/2005
	Details		Phase I Study of Tipifarnib and Radiotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma		Los Angeles, CA Boston, MA Ann Arbor, MI New York, NY Pittsburgh, PA Houston, TX San Antonio, TX Madison, WI		11/06/2005

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•   (0.9688)   Introgen and Texas Heart Institute Collaborate to Study Gene Therapy Approaches to Cardiovascular Disease (PR Newswire)
  ...Introgen is also conducting a Phase II clinical trial for INGN 201 in lung cancer and Phase I trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......INGN 241 (Adenoviral-mda7), for the treatment of solid tumors, is in Phase I clinical development....
  - Mar 14 7:30 AM ET
  
  
•   (0.9688)   Introgen and Texas Heart Institute Collaborate to Study Gene Therapy Approaches to Cardiovascular Disease (PR Newswire)
  ...Introgen is also conducting a Phase II clinical trial for INGN 201 in lung cancer and Phase I trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......INGN 241 (Adenoviral-mda7), for the treatment of solid tumors, is in Phase I clinical development....
  - Mar 14 7:30 AM ET
  
  
•   (0.9282)   Introgen`s p16 Cancer Therapeutic Receives Patent; Introgen Owns Exclusive Worldwide License From The University of Texas System (PR Newswire)
  ...The patent covers the inhibition of tumor growth using the p16 tumor suppressor gene encoded in an adenoviral vector when delivered via...... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
  - Sep 05 7:30 AM ET
  
  
•   (0.9115)   Introgen`s p53 Drug Awarded Patent (PR Newswire)
  The Board of Regents of The University of Texas System and Introgen Therapeutics, Inc. announced today that the U.S. Patent and Trademark Office has issued to The Board of Regents of The University of Texas System U.S.
  - Nov 08 4:36 PM ET
  
  
•   (0.9115)   The University of Texas System Awarded Patent for Use of p53 Gene in Combination With DNA Damaging Agents Utilizing Any Type of Delivery System (PR Newswire)
  The Board of Regents of The University of Texas System and Introgen Therapeutics, Inc. announced today that the U.S. Patent and Trademark Office has issued to The Board of Regents of The University of Texas System U.S.
  - Jun 14 1:08 PM ET
  
  
•   (0.9018)   Neurofibromatosis Nationwide Research Funding Increases to $37 Million for The Year 2001 (PR Newswire)
  The Texas Neurofibromatosis Foundation announced that approximately $37 million has been allocated for nationwide research for 2001, an increase of $7 million from 2000.
  - Jun 06 9:29 AM ET
  
  
•   (0.9018)   Neurofibromatosis Nationwide Research Funding Increases to $37 Million for The Year 2001 (PR Newswire)
  The Texas Neurofibromatosis Foundation announced that approximately $37 million has been allocated for nationwide research for 2001, an increase of $7 million from 2000.
  - Jun 06 9:29 AM ET
  
  
•   (0.9017)   New Family of Ten Cancer Related Genes Is Discovered By Researchers at The National Cancer Institute, The University of Texas` Southwestern Medical Center and M. D. Anderson Cancer Center (PR Newswire)
  ...Discovery of these tumor suppressor genes represents a joint collaborative effort by scientists at The University of...... have been incorporated into gene delivery systems and have blocked the growth of established tumors in animal models of lung cancer....... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer....
  - Oct 11 6:00 AM ET
  
  
•   (0.9017)   Introgen`s Anti-Cancer Therapy in Combination With Established Cancer Treatments Awarded Patent (PR Newswire)
  ... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
  - Sep 06 7:30 AM ET
  
  
•   (0.8912)   M.D. Anderson and Baylor will turn neurosurgery programs into one
  
  
•   (0.8912)   Epilepsy: More Common than Thought? (HealthSCOUT News)
  ..." Causes can range from trauma to the brain, infections, encephalitis, parasites and malaria to tumors,...
  - Jan 26 3:04 AM ET
  
  
•   (0.8792)   Oates to Have Surgery for Brain Tumor (AP)
  Former Texas Rangers manager Johnny Oates, diagnosed this month with a brain tumor, will undergo surgery Tuesday.
  - Nov 19 7:36 PM ET
  
  
•   (0.8792)   Introgen Gene Therapy Featured in Abstract and Published in Circulation, Journal of the American Heart Association (PR Newswire)
  ... trials for INGN 201 in additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......Introgen`s second product candidate, INGN 241 (Adenoviral-mda7) for the treatment of solid tumors, is in Phase I clinical development....
  - Oct 18 7:00 AM ET
  
  
•   (0.8658)   Consortium of international hospitals receives $11 million to conduct study of genetic brain tumors
  
  
•   (0.8658)   Ex-Rangers Manager Has Brain Tumor (AP)
  Former Texas and Baltimore manager Johnny Oates has been diagnosed with the most aggressive form of primary brain tumors.
  - Nov 09 12:42 PM ET
  
  
•   (0.8658)   Former Rangers Manager Oates Diagnosed with Brain Tumor (Reuters)
  Former Texas Rangers and Baltimore Orioles manager Johnny Oates has been diagnosed with a brain tumor and will undergo surgery at the end of the month in Virginia.
  - Nov 08 7:25 PM ET
  
  
•   (0.8658)   Ex-Rangers Manager Johnny Oates Has Brain Tumor (Reuters)
  Former Major League Baseball player and manager Johnny Oates has a brain tumor and will have surgery at the end of the month.
  - Nov 08 9:05 PM ET
  
  
•   (0.8658)   New treatment offers hope for brain-cancer patients
  
  
•   (0.8658)   APEX Award Given to Introgen in Recognition of Facility Design And Contribution (PR Newswire)
  Introgen Therapeutics, Inc. announced today that it received the 2000 Award for Project Excellence, from the Greater Houston Chapter of the Associated General Contractors of America for its facilities in Houston, Texas.
  - Dec 27 8:01 AM ET
  
  
•   (0.8511)   Texas Hold`em Tournament in NY to benefit Children`s Brain Tumor Foundation
  
  
•   (0.8510)   Padres Acquire Left-Handed Reliever (AP)
  ...Ramsay underwent surgery Jan. 23 to remove a brain tumor....
  - Apr 03 8:18 PM ET
  
  
•   (0.8510)   New Lance Armstrong Cancer Program to Offer Latest Shaped Beam Technology To Treat Tumors (PR Newswire)
  ... focused radiation therapy technology that enables physicians to treat tumors of the brain, head, neck, spine, liver, lung and prostate without harming surrounding healthy......By shaping a radiation beam to mirror the exact size and shape of the tumor, the radiation dosage can be administered more precisely....
  - Nov 01 4:59 AM ET
  
  
•   (0.8510)   Endocrine and cardiovascular late effects among adult survivors of childhood brain tumors: Childhood Cancer Survivor Study
  
  
•   (0.8510)   A day in the life of a pro football scout (The Sporting News)
  ...In 1994, Janet died from complications of a brain tumor....
  - Mar 19 5:20 PM ET
  
  
•   (0.8351)   M. D. Anderson neurosurgeon, Amy Heimberger, M.D., receives presidential award
  
  

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