Trials and Noteworthy Treatments

			Treatment Next 25		Location		Last Updated
	Details		A Pilot Study to Evaluate the Effects of Vaccinations with HLA-A2-Restricted Glioma Antigen-Peptides in Combination with Poly-ICLC for Children with Newly Diagnosed Malignant or Intrinsic Brain Stem Gliomas (BSG) or Incompletely Resected Non-Brainstem High-Grade Gliomas (HGG) or Recurrent Unresectable Low-Grade Gliomas (LGG) or Recurrent High Grade Gliomas		Pittsburgh, PA		09/23/2009
	Details		A Phase I Trial and Pharmacokinetic Study of Trabectedin (Yondelis®, ET-743) in Children and Adolescents With Relapsed or Refractory Solid Tumors		Bethesda, MD		04/22/2009
	Details		A Phase I/II Trial of ZD6474 for Patients With Recurrent High-Grade and Progressive Low-Grade Gliomas		Bethesda, MD		04/22/2009
	Details		Multiple Ascending Dose (MAD) Study of the IGF-1R Antagonist R1507 Administered as an Intravenous Infusion in Pediatric Patients With Advanced Solid Tumors.		Bethesda, MD		04/22/2009
	Details		Phase II Trial of RAD001 in Patients with Recurrent Low Grade Glioma		San Francisco, CA		04/06/2009
	Details		A Pilot Study to Evaluate the Effects of Vaccinations with HLA-A2-Restricted Glioma Antigen-Peptides in Combination with Poly-ICLC for Adults with High-Risk WHO Grade II Astrocytomas and Oligo-Astrocytomas		Pittsburgh, PA		01/06/2009
	Details		Quality of Life in Patients with Brain Tumors, Skull Base Tumors & Pituitary Adenomas Undergoing Surgical Resection		Santa Monica, CA		11/29/2008
	Details		Bevacizumab (Avastin) and Irinotecan (CPT-11) in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma		San Francisco, CA Washington, DC Chicago, IL Boston, MA Bethesda, MD Durham, NC Philadelphia, PA Pittsburgh, PA Memphis, TN Seattle, WA		11/08/2008
	Details		Gliogene: An International Brain Tumor Study		Houston, TX		07/24/2008
	Details		A Phase II Study of Temozolomide (temodar) in the Treatment of Adult Patients with Supratentorial Low Grade Glioma		San Francisco, CA		10/03/2007
	Details		Determination of the In-Tumor-Concentration of Imatinib Mesylate (Gleevec) in Malignant Glioma After Oral Administration		Baltimore, MD		08/20/2007
	Details		A Phase II Trial With Bevacizumab (Avastin) and Irinotecan (CPT-11) for Patients With Primary Brain Tumors and Progression After Standard Therapy		Copenhagen, Denmark		08/18/2007
	Details		Brain Mapping for Brain Tumors		Boston, MA		08/18/2007
	Details		Functional image guided removal of brain tumors		Manhasset, NY		08/18/2007
	Details		Phase 1 Trial Gamma Knife For Primary Brain Tumors - Gliomas.		Birmingham, AL		08/18/2007
	Details		A Phase II Study of a Temozolomide-Based Chemoradiotherapy Regimen for High-Risk Low-Grade Gliomas		Phoenix, AZ New Haven, CT Lewes, DE Fort Lauderdale, FL Jacksonville, FL Jacksonville, FL Miami, FL Columbus, GA Dubuque, IA Detroit, MI Kalamazoo, MI Lambertville, MI Rochester, MN Rochester, MN Saint Louis Park, MN Springfield, MO Omaha, NB Goldsboro, NC Lebanon, NH Long Branch, NJ Mount Holly, NJ Albuquerque, NM Buffalo, NY Utica, NY , OH Akron, OH Cleveland, OH Tulsa, OK Portland, OR Philadelphia, PA Philadelphia, PA Wynnewood, PA Greenville, SC Kingsport, TN Salt Lake City, UT Madison, WI		05/01/2007
	Details		Safety Study of Tarceva in Children With Refractory and Relapsed Malignant Brain Tumors and Newly Diagnosed Brain Stem Glioma		Villejuif, France		04/15/2007
	Details		Pilot Randomized Study of Modafinil for Treatment of Fatigue and Neurobehavioral Dysfunction in Patients With Primary Brain Tumors		Los Angeles, CA		05/29/2006
	Details		Genetic Epidemiology of Adult-Onset Glioma		Louisville, KY		05/27/2006
	Details		Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors		Washington, DC Chicago, IL Boston, MA Bethesda, MD Philadelphia, PA Pittsburgh, PA Memphis, TN Houston, TX Seattle, WA		05/27/2006
	Details		Phase 2 Study of Vinblastine in Children With Recurrent or Refractory Low Grade Glioma		Toronto, Ontario, , CANADA		05/21/2006
	Details		A Phase I Study of Tomotherapy in Patients With Benign Brain Tumour		Edmonton, Alberta, Canada		05/04/2006
	Details		Phase II Study of Temozolomide in Patients With Supratentorial Low-Grade Glioma		San Francisco, CA		05/02/2006
	Details		Pilot Study of the Safety and Accuracy of Fluorothymidine F 18 Positron Emission Tomography in Detecting Recurrent Disease in Patients With Gliomas		Seattle, WA		05/01/2006
	Details		Pharmacological intervention for learning impaired children surviving treatment for cancer.		Durham, NC		12/03/2005

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•   (0.9115)   Survival rates and patterns of care for patients diagnosed with supratentorial low-grade gliomas: data from the SEER program, 1973-2001.
  
  
•   (0.9017)   Phase II Trial of Temozolomide in Patients With Progressive Low-Grade Glioma
  
  
•   (0.9017)   Carboplatin Effective Against Low-Grade Glioma
  
  
•   (0.8912)   Survival rates in patients with low-grade glioma after intraoperative magnetic resonance image guidance.
  
  
•   (0.8912)   Outcome of children with centrally reviewed low-grade gliomas treated with chemotherapy with or without radiotherapy on Children`s Cancer Group high-grade glioma study CCG-945.
  
  
•   (0.8912)   Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients.
  
  
•   (0.8912)   Effects of radiotherapy on cognitive function in patients with low-grade glioma measured by the folstein mini-mental state examination.
  
  
•   (0.8912)   Phase II Trial of Temozolomide in Patients With Progressive Low-Grade Glioma.
  
  
•   (0.8792)   Temozolomide three weeks on and one week off as first line therapy for patients with recurrent or progressive low grade gliomas.
  
  
•   (0.8792)   Late sequela after treatment of childhood low-grade gliomas: a retrospective analysis of 69 long-term survivors treated between 1983 and 2003.
  
  
•   (0.8792)   Gamma knife surgery for low-grade gliomas.
  
  
•   (0.8792)   Monitoring temozolomide treatment of low-grade glioma with proton magnetic resonance spectroscopy.
  
  
•   (0.8658)   Radiation Linked to Cognitive Decline in Brain Cancer
  
  
•   (0.8658)   Chromosome 1p loss: A favorable prognostic factor in low-grade gliomas.
  
  
•   (0.8510)   RTOG Reports That Chemotherapy Added to Radiotherapy Improves Survival (For low grade gliomas)
  
  
•   (0.8510)   Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
  
  
•   (0.8510)   Considerations on the Role of Chemotherapy and Modern Radiotherapy in the Treatment of Childhood Low Grade Glioma.
  
  
•   (0.8510)   Recurrent low-grade gliomas: the role of fractionated stereotactic re-irradiation.
  
  
•   (0.8510)   High response rate to cisplatin/etoposide regimen in childhood low-grade glioma.
  
  
•   (0.8510)   Progress in long-term survival in adult patients with supratentorial low-grade gliomas: a population-based study of 993 patients in whom tumors were diagnosed between 1970 and 1993.
  
  
•   (0.8510)   Surgical removal of corpus callosum infiltrated by low-grade glioma: functional outcome and oncological considerations.
  
  
•   (0.8510)   Pitfalls in the assessment of disability in individuals with low-grade gliomas.
  
  
•   (0.8351)   New vaccine trial opens for pediatric (ages 3 to 20) high grade, low grade and brainstem glioma
  
  
•   (0.8351)   MGMT methylation: A marker of response to temozolomide in low-grade gliomas.
  
  
•   (0.8351)   Efficacy of fractionated stereotactic reirradiation in recurrent gliomas: long-term results in 172 patients treated in a single institution.
  
  

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