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Trials and Noteworthy Treatments


	Treatment	Location	Last Updated

Details	A Phase I Study of MK-0752, a Notch Inhibitor, in Patients With Metastatic or Locally Advanced Breast Cancer and Other Solid Tumors	San Francisco, CA	04/12/2010

Details	ABTC09-04 - A Biomarker and Phase II Study of GDC-0449 in Patients with Recurrent Glioblastoma Multiforme	San Francisco, CA	04/12/2010

Details	A Phase II study of Bevacizumab (Avastin) plus Temodar and Tarceva during and after Radiation Therapy in patients with newly diagnosed Glioblastoma or Gliosarcoma	San Francisco, CA	01/11/2010

Details	ABTC 04-03: A Phase I Study of Vorinostat (Suberolyanilide Hydroxamic Acid [SAHA]) in Combination with Temozolomide in Patients with Malignant Gliomas	San Francisco, CA	01/11/2010

Details	CERN08-02 - A Phase II Study of Dose-Dense Temozolomide and Lapatinib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial and Spinal Cord Ependymoma	San Francisco, CA	01/11/2010

Details	Phase II Study of Gamma-Knife Radiosurgery Using Magnetic Resonance Spectroscopy for Target Definition in Patients with Recurrent Glioma	San Francisco, CA	01/11/2010

Details	ABTC07-01-Phase I Trial of Aflibercept (VEGF Trap) with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients with Malignant Glioma	San Francisco, CA	07/07/2009

Details	PHASE II, single-arm, open-label investigation of HSPPC-96 vaccine with concurrent temozolomide in patients with newly diagnosed Glioblastoma Multiforme	San Francisco, CA	07/07/2009

Details	A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas	San Francisco, CA	04/06/2009

Details	Phase II Trial of RAD001 in Patients with Recurrent Low Grade Glioma	San Francisco, CA	04/06/2009

Details	Phase II Study Of 7 Days On/7 Days Off Temozolomide In Patients With High-Grade Glioma	San Francisco, CA	01/17/2008

Details	A Phase II Study of Temozolomide (temodar) in the Treatment of Adult Patients with Supratentorial Low Grade Glioma	San Francisco, CA	10/03/2007

Details	Phase II Study of Temozolomide in Patients With Supratentorial Low-Grade Glioma	San Francisco, CA	05/02/2006

News Stories

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(0.9352) Introgen Therapeutics and the University of California Collaborate to Study Gene Therapy Approaches to Arthritis (PR Newswire)
...This discovery established the concept of using therapies based upon tumor suppressor genes to treat rheumatoid arthritis and potentially o......additional cancer indications including prostate, ovarian, bladder, brain, and breast cancer.......candidate, INGN 241 (Adenoviral-mda7), for the treatment of solid tumors, is in Phase I clinical development....
- Jun 05 7:30 AM ET
(0.9352) 1st European C21 Investor Conference: Call for Delegates (PR Newswire)
The 1st European C21 Investor begins a series of European investment conferences to showcase public and late-stage private biotechnology and converging IT companies.
- Sep 22 8:15 AM ET
(0.9281) California Pizza Kitchen`s Seven Signature Frozen Pizzas Now Available in the Chicago Area (Business Wire)
...Young Associates Board of the Gus Foundation will host an evening to raise funds for research and treatment of pediatric brain tumors at Children`s Memorial Hospital....
- Apr 03 5:30 PM ET
(0.9115) `Tour of the California Alps` fundraiser for brain tumor research!
(0.9115) McDonnell Foundation Announces Grants for 2003, The 21st Century Science Research Awards; Grants Continue the Commitment to Founder`s Vision
(0.9115) `Tour of the California Alps` fundraiser for brain tumor research!
(0.9115) Ken Stover is riding his bike in the Tour of the California Alps to raise money for the Musella Foundation.
(0.8912) Supreme Court to Tackle Medical Marijuana Issue (Reuters)
...marijuana is seen as an essential part of the medical arsenal keeping her alive despite a brain tumor, seizures and partial paralysis that has confined her to a wheelchair....
- Mar 25 9:11 AM ET
(0.8912) Brain Tumor Activists Score Victory in California (PR Newswire)
Despite the term "benign," a benign brain tumor poses serious challenges for patients.
- Sep 27 2:16 PM ET
(0.8792) Stem cell research offers new hope for Brain tumor patients - Californians to decide on Stem Cell Initiative in November
(0.8792) Supreme Court to Tackle Medical Marijuana (Reuters)
...marijuana is an essential part of the medical arsenal keeping her alive despite a brain tumor, seizures and partial paralysis that has confined her to a wheelchair....
- Mar 26 4:16 PM ET
(0.8792) The Candle Foundation Awards Charitable Grants to Non-Profit Organizations; Candle Corporation Hosts Southern California Grant Recipients (PR Newswire)
...Advocacy Center for the Partially Sighted Sharp Healthcare Children`s Dental Health Clinic Social Action Community Health Operation USA Yo San University University of Central Florida Men Stopping Violence Bay Area Rescue Mission National Brain Tumor Foundation ``We receive many exciting and qualified applicants,...
- Mar 06 1:14 PM ET
(0.8658) A new hope for brain tumor patients
(0.8658) Medical privacy law said to be chilling cancer studies Scientists fight for fast access to patient files
(0.8658) New Institute Integrates Powerful Tools of Physical, Mathematical, and Engineering Sciences With Biomedical Research (Business Wire)
The creation of the Institute for Bioengineering, Biotechnology and Quantitative Biomedical Research, announced today by Governor Gray Davis, represents the next revolution in biomedical research.
- Dec 07 6:11 PM ET
(0.8658) Maureen Reagan Undergoing Cancer Treatment (PR Newswire)
Maureen Reagan, the daughter of former President Ronald Reagan and actress Jane Wyman, is undergoing a highly aggressive treatment at the John Wayne Cancer Institute at Saint John`s Health Center in Santa Monica, California, for malignant melanoma, the deadliest form of skin cancer.
- Jan 09 5:00 AM ET
(0.8655) Calif. jury award to smoker may set trend-experts (Reuters Securities)
Lawyers for a smoker riddled with cancer took their history-making lawsuit to a Los Angeles court known as ``The Bank`` because of its reputation for big liability payouts.
- Jun 07 5:37 PM ET
(0.8510) CANCER PHYSICIAN INVENTS TEST FOR NEW DRUGS THAT CUT OFF TUMOR`S BLOOD SUPPLY
(0.8510) Spectrum Pharmaceuticals Presents Data on EOquin(TM) as a Radiation Sensitizer at the Annual Meeting of American Association of Cancer Research (AACR) in Anaheim, California
(0.8510) A Day at the Ranch Benefit - to raise awareness and to fund brain tumor research! - June 25 th 2005 - Loomis, California
(0.8510) PR Newswire Northern California Summary, Friday, November 9, 2001 Up to 2:00 p.m. PT (PR Newswire)
... VIEW) SGI Completes Agreement With NEC and NEC Soft SFF031 11/09/2001 16:29 r f bc-CA-Nat-Brain-...... SGI Completes Agreement With NEC and NEC Soft SFF031 11/09/2001 16:29 r f bc-CA-Nat-Brain-Tumor (OAKLAND) Brain Tumors Not Always Fatal - National Brain Tumor Foundation Provides Help and...
- Nov 09 5:47 PM ET
(0.8510) Medical Privacy Law is Threatening Cancer Studies - See How You Can Make a Difference (with no cost and about 1 minute of your time)
(0.8510) Maureen Reagan`s Cancer Spreads to Her Brain (PR Newswire)
Maureen Reagan, the daughter of former President Ronald Reagan and actress Jane Wyman, has been re-hospitalized at Mercy San Juan Hospital in Carmichael, California, and is undergoing whole brain radiation for malignant melanoma that has spread to her brain.
- Jul 13 6:00 AM ET
(0.8510) EpiGenX Rounds Out Scientific Advisory Board with Nobel Laureate (Business Wire)
...and is a leading expert in the field of methylation, including identifying non-random and tumor-specific methylation patterns in human malignancies.......Dr Costello is a member of the Brain Tumor Research Center at UCSF and has had his work featured in editorials published in Nature Genetics,...
- May 09 11:26 AM ET
(0.8510) EpiGenX Rounds Out Scientific Advisory Board with Nobel Laureate (Business Wire)
...and is a leading expert in the field of methylation, including identifying non-random and tumor-specific methylation patterns in human malignancies.......Dr Costello is a member of the Brain Tumor Research Center at UCSF and has had his work featured in editorials published in Nature Genetics,...
- May 07 11:40 AM ET

Frequently Asked Questions

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  (0.8351) How do you get a brain tumor? What can you do to treat a brain tumor? Can you prevent a brain tumor? Will it ever just go away by itself? Why do you go into a coma? How long are you in a coma before you die? What percent of Americans have brain tumors? Is it likely since my great grandmother had a brain tumor that I will?

  (0.8351) My sister-in-law just had surgery to remove a tumor identified as glioblastoma multiforme. The tumor was the size of a lemon. The doctor says that if it recurs, she is not a candidate for another surgery. How likely is ? What are the chances of complete recovery?

  (0.8351) Having reviewed some statistical information, I still want to know: how many GBMs are diagnosed say, in a year, or by state, or by country. If, on average, a neurosurgeon only treats one per year, they canno be THAT common, can they?

  (0.7967) I found out 18 months ago that I have an infiltrating astrocytoma grade 2, deeply situated within the brain and unable to be removed. I had radiotheraphy over a year ago and subsequent MRI scans have been positive. I suffered with seizures, but the last 12 months have been seizure free. I am now looking to reapply for my driver's license. One doctor said, yes, it was possible I might get it back; another said I must wait another 12 seizure free months; my neurosurgeon said I was wasting my time reapplying because as long as the tumor remains in my head there is always the chance seizures could return, even a grand-mal seizure. I know being able to drive might seem trivial, but I really would like an opinion on my chances of driving again.

  (0.7967) I had a seizure on January 2, 2003. The hospital missed a tumor with no MRI and sent me home. On May 2, I had a grand mal and they found an oligo. I had surgery May 15 and 90% was removed. I am being watched by a neuro-oncologist and getting MRIs every three months, so far so good. I feel perfect with the exception of a bit of short term memory loss due to Trileptal I am sure. I am at work since July 15. I am planning my cruise vacation and airline flight, I work out and run around and do everything as I did before the resection. My question is: the NY DMV said that, for epileptics, the rule to drive is one year but six months is allowed. I said I am not an epileptic and explained about the tumor and that the seizure was a result of that. I told them that I am on meds and it states in the drug insert that you can drive after you know how you react to the med. The medical board said I can drive when the doctor says it is OK to drive because my circumstance is different. I am responsible and if there is any med change I will not drive until I see how I am. What is the actual time line for this? I am so depressed about being unable to drive that I may require an antidepressent soon as well. Can the neurologist approve me driving?

  (0.7967) Can people that have had brain tumors be allowed to drive? My husband had a tumor 1 1/2 years ago; he is almost done with chemotherapy and has never had a seizure. The tumor is gone as of the last CT scan. I am from Butler PA, and I cannot find a doctor who will let him.

  (0.7742) URGENT: Please inform as soon as possible; we have to decide whether we (Sharon Mussen, a 35 year-old social worker, accompanied by one or both parents) should go to Germany for treatment of a high-grade oligoastrocytoma, which has advanced from Grade 2 in 2000, to Grade 3 in 2004, to probably Grade 4 currently. We are awaiting the pathology analysis of the regrown tumor tissue resected last month. It is of life-threatening urgency because the growth seems to be accelerating. Can the receiver of this note, or some other brain tumor physician or researcher to whom you may refer this difficult question, provide us with good OBJECTIVE information and an opinion, very quickly, about the effectiveness of the treatment performed by Dr. Klaus Maier-Hauff (and his clinic at Berlin's Charite Hospital) where it is claimed that a brain-tumor will absorb an applied dosage of sub-microscopic, magnetic, iron-oxide particles which, if we understand correctly, heat and weaken or destroy tumor cells (with no permanent damage to healty tissue or the brain-centered faculties of language, memory, motor/movement, etc). The method has been variously described as Nanotechnology, Nanopartical Application, Thermotherapy, and perhaps other descriptive names. The literature that we have found (mostly at their web-site) is put out by the clinic and/or the German government information services. There is mention, in their web-site literature, of research that is on-going or scheduled to begin. But, even if rigorous medical research has not as yet been completed,we want to base our decision on at least the opinion of knowledgable, non-involved experts. A well-known neurosurgeon here dismissed the idea by telling us that "we tried that method some years ago and found it did not work"; however, as you and we know, nanotechnology is relatively new and, therefore, rapidly improving. Again we need expert, objective opinion. A brief review of the medical situation: In the year 2000, Sharon suffered a grand mal seizure; was taken to

  (0.7742) I have been diagnosed with a Chordoma brain tumor located somewhere behind my cheekbone below my right eye. The neurologist I was sent to misdiagnosed the tumor from the MRI and thought it to be a tumor that he could remove most of and then follow up with the gamma knife. However, when he saw that it was not what he thought, he cut away what he could to have it biopsied. Several weeks later, he told me that he could not perform the surgery I needed to totally remove it, nor would the gamma knife work due to two main arteries which lie very close to the tumor. He has told me about the next surgery and what damage it will do and I am horrified. I have already lost some vision in my right eye and the entire side of my right face is completely numb as are parts of my mouth. I have seen several sites with much less invasive surgery for this type of tumor, but I am not a doctor. I need advice.

  (0.7742) What are the possible side effects of radiation?

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