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Trials and Noteworthy Treatments

  Treatment Location Last Updated
Details ABTC07-01-Phase I Trial of Aflibercept (VEGF Trap) with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients with Malignant Glioma San Francisco, CA 07/07/2009
Details PHASE II, single-arm, open-label investigation of HSPPC-96 vaccine with concurrent temozolomide in patients with newly diagnosed Glioblastoma Multiforme San Francisco, CA 07/07/2009
Details A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas San Francisco, CA 04/06/2009
Details Phase II Trial of RAD001 in Patients with Recurrent Low Grade Glioma San Francisco, CA 04/06/2009
Details A Phase II study of Bevacizumab (Avastin?) plus Temodar and Tarceva during and after Radiation Therapy in patients with newly diagnosed Glioblastoma or Gliosarcoma San Francisco, CA 01/09/2009
Details NABTC05-02 - Phase I/II Studies of BAY 43-9006 (sorafenib) in Combination with OSI-774 (erlotinib), R115777 (tipifarnib) or CCI-779 (temsirolimus) in Patients with Recurrent Glioblastoma Multiforme or Gliosarcoma. San Francisco, CA 01/09/2009
Details Phase II Study Of 7 Days On/7 Days Off Temozolomide In Patients With High-Grade Glioma San Francisco, CA 01/17/2008
Details A Phase II Study of Temozolomide (temodar) in the Treatment of Adult Patients with Supratentorial Low Grade Glioma San Francisco, CA 10/03/2007
Details NABTC 04-03: A Phase I Study of Vorinostat (Suberolyanilide Hydroxamic Acid [SAHA]) in Combination with Temozolomide in Patients with Malignant Gliomas San Francisco, CA 10/03/2007
Details Phase I/II trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine For Patients With Recurrent High Grade Glioma San Francisco, CA 10/03/2007
Details Phase II Study of Temozolomide in Patients With Supratentorial Low-Grade Glioma San Francisco, CA 05/02/2006

News Stories

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  (0.8351)   my sister-in-law just had surgery to remove a tumor identified as glioblastoma multiforme. the tumor was the size of a lemon stage 4. the doctor says that if it recurs, she is not a candidate for another surgery. how likely is it to recur? what is the survival period with chemo and radiation. what are the chances of complete recovery

  (0.8351)   I am trying to find statistical information re GBM IVs. Specifically, is there any data on survival statistics based on size, location, types of treatment, age at dx (and statistical variance)? All I have been able to find is ~~average survival is 12-18 months~~, but I~m seeing several 6 to 20 year survivor stories. Are these atypical?

  (0.8351)   having reviewed some statistical information, I still want to know... How many GBM IVs are diagnosed say, in a year, or by state, or by country...if on average, a neurosurgeon only treats one per year, they can~t be THAT common, can they? BTW, the seer statistics are completely unhelpful.

  (0.7967)   I found out 18 months ago that I have an infiltrating astrocytoma grade 2, deeply situated within the brain and unable to be removed. I had radiotheraphy over a year ago and subsequent MRI scans have been positive. I suffered with seizures, but the last 12 months have been seizure free. I am now looking to reapply for my driver's license. One doctor said, yes, it was possible I might get it back; another said I must wait another 12 seizure free months; my neurosurgeon said I was wasting my time reapplying because as long as the tumor remains in my head there is always the chance seizures could return, even a grand-mal seizure. I know being able to drive might seem trivial, but I really would like an opinion on my chances of driving again.

  (0.7967)   my best friend has recently learned he has a cyst deep in the brain and has been advised that California has a medical study using some form of drug therapy fot this condition. Is there some website that I could find to see more information of the outcome for this disease and the newer type of drug studies being dont to shrink or disolve the cyst. Any help would be appreciated in learning about this ...thanks

  (0.7967)   How do you get a brain tumor? What can you do to treat a brain tumor? Can you provent a brain tumor? Will it ever just go away by its self? Why do you go into a coma? how long are you in a coma before you die? what percent of amaricanes have brain tumors? Is it likely scence my great grandmother had a brain tumor that i will?

  (0.7967)   Can people that have had brain tumors be allowed to drive? My husband had a tumor 1 1/2 years ago, he is almost done with chemo, and has never had a seizure. The tumor is gone as of the last cat scan. I am from Butler PA, and I cannot find a doctor who will let him. Thank you, Melissa Steighner

  (0.7742)   URGENT: Please inform as soon as possible; we have to decide whether we (Sharon Mussen, a 35 year-old social worker, accompanied by one or both parents) should go to Germany for treatment of a high-grade oligoastrocytoma, which has advanced from Grade 2 in 2000, to Grade 3 in 2004, to probably Grade 4 currently. We are awaiting the pathology analysis of the regrown tumor tissue resected last month. It is of life-threatening urgency because the growth seems to be accelerating. Can the receiver of this note, or some other brain tumor physician or researcher to whom you may refer this difficult question, provide us with good OBJECTIVE information and an opinion, very quickly, about the effectiveness of the treatment performed by Dr. Klaus Maier-Hauff (and his clinic at Berlin's Charite Hospital) where it is claimed that a brain-tumor will absorb an applied dosage of sub-microscopic, magnetic, iron-oxide particles which, if we understand correctly, heat and weaken or destroy tumor cells (with no permanent damage to healty tissue or the brain-centered faculties of language, memory, motor/movement, etc). The method has been variously described as Nanotechnology, Nanopartical Application, Thermotherapy, and perhaps other descriptive names. The literature that we have found (mostly at their web-site) is put out by the clinic and/or the German government information services. There is mention, in their web-site literature, of research that is on-going or scheduled to begin. But, even if rigorous medical research has not as yet been completed,we want to base our decision on at least the opinion of knowledgable, non-involved experts. A well-known neurosurgeon here dismissed the idea by telling us that "we tried that method some years ago and found it did not work"; however, as you and we know, nanotechnology is relatively new and, therefore, rapidly improving. Again we need expert, objective opinion. A brief review of the medical situation: In the year 2000, Sharon suffered a grand mal seizure; was taken to

  (0.7742)   I have been diagnosed with a Chordoma brain tumor located somewhere behind my cheekbone below my right eye. The neurologist I was sent to misdiagnosed the tumor from the MRI and thought it to be a tumor that he could remove most of and then follow up with the gamma knife. However, when he saw that it was not what he thought, he cut away what he could to have it biopsied. Several weeks later, he told me that he could not perform the surgery I needed to totally remove it, nor would the gamma knife work due to two main arteries which lie very close to the tumor. He has told me about the next surgery and what damage it will do and I am horrified. I have already lost some vision in my right eye and the entire side of my right face is completely numb as are parts of my mouth. I have seen several sites with much less invasive surgery for this type of tumor, but I am not a doctor. I need advice.

  (0.7742)   What are the possible side effects of radiation?

  (0.7742)   I had a seizure on January 2nd 2003. Hospital missed a tumor with no Mri and sent me home. May 2nd I had a grand MAl and they found an oligo. I had surgery May 15 and 90% is removed. I am being watched by a neuro-oncologist and getting Mri~s every three months and so far so good. I feel perfect with the exception of a bit of short term memory loss due to trileptal medicine i am sure. I am at work since july 15. Planning my cruise vacation and airline flight , work out and run around and do everything as I did before the resection. My question is the NY DMV said that for epileptics the rule to drive is one year but six months is allowed. I said I am not an epileptic and explained about the tumor and that the seizure was a result of this and that I am on meds and it states in the insert of them that you can drive after you know how you react to them. The medical board said I can drive when the doctor says it is OK to drive because my circumstance is different. I am responsible and if there is any med change I will not drive untill I see how I am. What is the actual time line for this? I am so depressed without being able to drive that I may require an anti depressent soon as well. Can the neurologist approve me driving.

  (0.7742)   MY DAUGHTER-IN-LAW HAD AND ASTROCYTOMAS TUMOR REMOVED FROM HER BRAIN ON MAY 9, 2002. THE NEUROSURGEON AS OF MAY 21, 2002 STILL HAS NOT GIVEN HER A PATHOLOGY REPORT BUT IS INSISTING SHE START RADIATION TREATMENT MONDAY TUES MAY 28, 2002. MY QUESTION IS, HOW AND WHERE IN ORANGE COUNTY CALIFORNIA CAN WE GET A SECOND OPINION AND WHO DO WE CONTACT FOR IT? dOES THE NEUROPATHOLOGIST NEED TO SEE HER OR JUST A FROZEN SECTION OF THE REMOVED TUMOR? cAN THIS BE DONE BY PHONE AND CO-OPERATON WITH THE HOSPITAL? OR DOES SHE HAVE TO WAIT UNITL jUNE 3 2002 WHEN HER NEUROSURGEON SAID TO COME BACK FOR HER PATHOLOGY RESULTS.

  (0.7742)   I had a relationship with a someone over 4 years ago. Who later we found out she had a brain tumour, she did not know it at the time. I would like to know if brain tumours can be caught from close contact. After a while i noticed that i started getting spots on my head, (although they have all but disapeared now and only on a few occassion had really acute sharp headache nothing of which i have never experience before. The girl i met we lossed contact although i was engaged to her and did all to be with her but she would not allow it. She was given 2 years to live in June 1998 although i heard from her briefly in june 2001, all i know that it was inoperable and in the frontal lobe region. We only spent 2 weeks together in California (1998) I live in the UK we met on the internet. After she told me i kept in contact with her for over a year until she started sending letters back and hanging up the phone. It was a very complicated situation. bec she already lived with someone and had a 7 year old child also. Actually im not to worried about my health at all Bec what happens happens. I just wondered thats all if brain tumours are contagious. In fact after i had met her and came back to the UK i was ill for 2 months and had varrious hospital tests, blood, urine etc the end result the doctor just said it was a virus, I was very odd, faint all the time my hand seized up and felt sick all the time. I wondered if this could of been a reaction from our contact. Lucky for me i have never had that accuring again. Just like to finish this that my heart goes out to all those who find themselves in such a postion of being terminally ill. And esp to the one i loved. Plse dont post this on your FAQ, well you can post the Question are brain tumours contagious? thanks




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