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Trials and Noteworthy Treatments

  Treatment Next 25 Location Last Updated
Details A Pilot Study to Evaluate the Effects of Vaccinations with HLA-A2-Restricted Glioma Antigen-Peptides in Combination with Poly-ICLC for Children with Newly Diagnosed Malignant or Intrinsic Brain Stem Gliomas (BSG) or Incompletely Resected Non-Brainstem High-Grade Gliomas (HGG) or Recurrent Unresectable Low-Grade Gliomas (LGG) or Recurrent High Grade Gliomas Pittsburgh, PA 09/23/2009
Details Study of Fractionated Stereotactic Radiosurgery to Treat Large Brain Metastases Stanford, CA 09/01/2009
Details A phase II trial of PTK-787 in recurrent or progressive meningiomas Cincinnati, OH 08/27/2009
Details Phase I/II Trial for Patients with Recurrent Resectable Glioblastoma Multiforme Using Surgery with Implantable BCNU Polmer Followed by Post-operative Irinotecan and Bevacizumab Cincinnati, OH 08/27/2009
Details RTOG 0614 A Randomized, Phase III, Double-Blind, Placebo-Controlled Trial of Memantine for Prevention of Cognitive Dysfunction in Patients Receiving Whole-Brain Radiotherapy Cincinnati, OH 08/27/2009
Details RTOG 0825 Phase III Double-Blind Placebo-Controlled Trial of Conventional Concurrent Chemoradiation and Adjuvant Temozolomide Plus Bevacizumab versus Conventional Concurrent Cincinnati, OH 08/27/2009
Details A Phase II Safety and Tolerability Study of Avastin When Added to Single-Agent Chemotherapy to Treat Patient With Breast Cancer Metastatic to Brain West Palm Beach, FL
Charlotte, NC
Durham, NC 		06/16/2009
Details Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer Oceanside, NY 05/20/2009
Details A Phase I Trial and Pharmacokinetic Study of Trabectedin (Yondelis®, ET-743) in Children and Adolescents With Relapsed or Refractory Solid Tumors Bethesda, MD 04/22/2009
Details Multiple Ascending Dose (MAD) Study of the IGF-1R Antagonist R1507 Administered as an Intravenous Infusion in Pediatric Patients With Advanced Solid Tumors. Bethesda, MD 04/22/2009
Details An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-Grade Glioma Bethesda, MD 04/15/2009
Details A Multicenter Prospective Analysis of Treatment Outcomes in Patients with Large Acoustic Neuromas Receiving Subtotal Resection with Back up Stereotactic Radiation Therapy Cincinnati, OH 04/06/2009
Details Phase III Randomized, Parallel Group, Multi-Centre Study in Recurrent Glioblastoma Subjects to Compare the Efficacy of AZD2171 [RECENTIN] Monotherapy and the Combination of AZD2171 with Lomustine to the Efficacy of Lomustine Alone Cincinnati, OH 04/06/2009
Details Phase III double blind, placebo controlled study of donepezil in irradiated brain tumor patients Houston, TX 04/03/2009
Details Quality of Life in Patients with Brain Tumors, Skull Base Tumors & Pituitary Adenomas Undergoing Surgical Resection Santa Monica, CA 11/29/2008
Details Monteris AutoLITT™ FIM Safety Trial for Recurrent/Progressive Brain Tumors Cleveland, OH
Cleveland, OH 		11/19/2008
Details A Phase II Trial of Thalidomide in combination with Temozolomide or CPT-11 in patients with recurrent anaplastic gliomas or glioblastoma multiforme Houston, TX 10/27/2008
Details AutoLITT™ FIM Trial - A Prospective First-In-Man (FIM) Safety Trial of the AutoLITT Laser Treatment of Recurrent/Progressive Brain Tumors Cleveland, OH 09/28/2008
Details A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Advanced Solid Tumors and Metastatic Brain Cancer New York, NY
Houston, TX
San Antonio, TX 		07/24/2008
Details Gliogene: An International Brain Tumor Study Houston, TX 07/24/2008
Details Phase ll Trial of Tumor Lysate-Pulsed Dendritic Cell Immunotherapy for Patients With Atypical or Malignant, Primary or Metastatic Brain Tumors of the Central Nervous System Los Angeles, CA 03/02/2008
Details NTI 0501: An Open-Labeled, Extended-Use of Human Corticotropin-Releasing Factor (hCRF) (Xerecept) Intended for Patients Who Participate in Dexamethasone-Sparing Studies NTI 0302 or NTI 0303 Kingston, Ontario, CANADA
Edmonton, Alberta, CANADA
Moncton, New Brunswick, CANADA
Ottawa, Ontario, CANADA
Toronto, Ontario, CANADA
Winnipeg, Manitoba, CANADA
Phoenix, AZ
La Jolla, CA
Palo Alto, CA
Sacramento, CA
Aurora, CO
Englewood, CO
Jacksonville, FL
Orlando, FL
Chicago, IL
Evanston, IL
Boston, MA
Detroit, MI
Winston-Salem, NC
Edison, NJ
Buffalo, NY
Columbus, OH
Columbus, OH
Portland, OR
Memphis, TN
Nashville, TN
Seattle, WA
Madison, WI 		03/01/2008
Details A Phase 1/11 Study of Topotecan by Intracerebral Clysis for the Treatment of Recurrent Primary Malignant Brain Tumors NEW YORK CITY, NY 08/20/2007
Details Phase II Study of Intrathecal I-3F8 in Patients With GD2-Expressing Central Nervous System and Leptomeningeal Neoplasms New York, NY 08/20/2007
Details Identification of factors associated with brain metastasis in women with breast cancer: development of a predictive nomogram Cleveland, OH 08/18/2007

News Stories

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  (0.9282)   What is your opinion on Dr Burzynskis antineoplaston therapy for brain tumors?

  (0.9203)   How do you get a brain tumor? What can you do to treat a brain tumor? Can you provent a brain tumor? Will it ever just go away by its self? Why do you go into a coma? how long are you in a coma before you die? what percent of amaricanes have brain tumors? Is it likely scence my great grandmother had a brain tumor that i will?

  (0.8912)   Hi , i have a question about brain tumors. A very close friend of mine was diagnosed with a very small brain tumor in the occipital lobe. He is taking some medication becuase the doctor says that surgery is not necessary. Will the brain tumor go away??? Is there any possibility of that happening?? Also, if an individual has a brain tumor, does that mean that he/she is a cancer patient?? Couldnt a person just have a brain tumor without having cancer?? please give me some information on my questions as soon as you can....it would mean alot to me.....thanks

  (0.8912)   How can you tell if you have a brain tumor, what are some symptoms?

  (0.8792)   Is it true that brain tumor~s can be caused by cell phones? And do frequent headaces result in brain tumors?

  (0.8792)   how serious is a brain tumor? What are the chances of survival after surgery of brain tumor? What is the recovery time after a brain tumor surgery? How long does a brain tumor surgery take?

  (0.8658)   I am a 15-year-old boy and I am scheduled for a CT scan for a brain tumor in two months. I came across a type of brain tumor/cancer called a brain stem glioma. I have alot of the common symptoms, like my eyes have a weird feel; it's not the clarity of them but the feeling of JUST my eyes being dizzy and weak. Also, and for the first time, I had serious double vision. I sometimes get headaches, my limbs feel weak and sketchy, my face feels numb, my eye lids open automatically when I sleep, I feel very drowsy, and my head has a load of pressure on it. I was wondering if there are any other types of brain tumors or illnesses which mimic my symptoms because the survival rates of a brain stem glioma are very low. I was also wondering if an MRI scan shows it better, because one website had info on MRI scans for brain stem glioma.

  (0.8658)   Hi, I am writing this letter in order to get some information about clinical trials for patience with brain tumor. I am italian and a few months ago my brother went under surgery to remove a brain tumor in the frontal part of the head. He has now finished the chemioterapy and at the moment he is responding quite well to the treatment, but the doctors think that his life expectancy is only 12 months. I have heard about genetic terapy, but I do not know where I can find the hospitals in europe that do it. I will be very grateful if you can give me some advise where to find hospitals that do this kind of terapy and other available treatments. Yours sincerely Domenico Muratore.

  (0.8658)   Does usage of mobile phones cause brain tumors or any kind of cancer and, if so, what are the damages, if any, to the brain on excessive mobile usage.

  (0.8658)   I have heard that some doctors believe that the psychotropic medication Risperdal may be causing brain tumors in patients who have taken it for several years. My 35 year old son has taken Risperdal since it was introduced. He recently had a brain tumor removed and the surgeon said he had never seen a tumor like it. There are 2 more tumors in his brain that will be monitored. Are you aware of a connection between Risperdal and strange benign brain tumors? Thank you. Brenda Wilkerson

  (0.8658)   What are the syptoms of brain tumors?

  (0.8658)   what usally is a sympton of a brain tumor

  (0.8658)   What kind of symptoms are common with brain tumors? Three years ago, I had a tumor removed from my right eye causing loss of sight in that eye. I haven~t had any symptoms since then. Just three months ago, I started having blind spots followed by cold sweats and intense headaches, and then vomiting. I~ve never had headaches before so this has kind of scared me. Does it sound like a brain tumor?

  (0.8658)   If a brain tumor is suspected, which test is needed to prove that there is no brain tumor present? Is A CT scan enough to say there is no tumor? IF an MRI is needed, is the contrast material needed?

  (0.8658)   Does being treated at a major brain tumor center result in a better outcome or an increased survival time for a brain tumor patient over what would be expected if they were treated at a small local hospital?

  (0.8510)   My Husband died of a brain tumor in 2002(anaplastic astrocytoma grade 3 - left frontal lobe). He had symptoms for a long time and we didn~t realize it was a brain tumor until the tumor began to bleed and caused stroke like symptoms. How long can a brain tumor remain dormant? His headaches started in the late 1980~s and his doctor did a cat scan and that was inconclusive. The doctor suggested an MRI but the Insurer wouldn~t pay for the procedure and the conclusion was stress was causing the headaches. In the early 1990~s the headaches continued and he began having other symptoms that we did not attribute to the headaches (projectile vomiting, loss of bowel and bladder control). These other symptoms were occaisional and we thought it was something he ate. In 1993 after my sister died of cancer we began taking an herbal tea (eissac) to prevent cancer and my husband continued to take this tea up until his tumor began bleeding in 2001. Is it possible the tumor was there from 1988? Was it possible the tea helped to prolong his being being able to live with the tumor being dormant? He still had the headaches and occaisional bouts of loss of bladder and bowel control and vomiting and short term memory loss. I know, obviously, if he had been diagnosed sooner he would have had a better chance of survival. But, was the tumor there as much as 10 or 15 years before it was found?

  (0.8510)   I have been researching but cannot really find any answers. My father was just diagnosed two months ago with a glioblastoma multiforme. His first cousin also had a brain tumor. Does this constitute a family history and does this mean my sister and I should have MRIs? t seems like there is conflicting information on whether there is a genetic component and if they can test for it.

  (0.8510)   My father, age 68, was diagnosed with a mixed anaplastic oligoastrocytoma brain tumor. The tumor was surgically removed and the the doctor said they were able to remove 95% of the tumor. He has undergone radiation therapy, and 32 days of chemotherapy (Temodar, 120 mg). He is currently taking another round of chemotherapy (Temodar, 300 mg x 5 days out of 28 days for 6 months). We are trying to find out what the survival rates for this type of brain cancer are? Also, are there any alternative treatments that have had success treating this type of brain tumor.

  (0.8510)   My father has a glioblastoma multi-form brain tumor, and I had a few questions that have been hanging around in my head for awhile, and no one has been able to answer them...I was wondring if you could answer a few of my questions. What this actually is. How it affects the body. What are the complications? How is it diagnosed? What are the symptoms? What is th treatment? Are there any lifestyle changes? Is there a plan that would help decrease your chances of contracting this? Thanks for your time and I will greatly appreciate your answers!

  (0.8510)   My 26 year old sister was diagnosed with GBM 4 three months back. The tumor has been completely removed and she has just finished her radiotherapy sessions along with a daily does on 100mg temodal. So far, she has responded well to this treatment aside from fatigue and some hairloss. She will now undergo a 6 month maintainence schedule of 5 days temodal in a 28 day cycle. I want to know if any nutritional/ dietary changes and an exercise regime can help. where can i read up on this.

  (0.8510)   My husband has a grade 4 mixed glioma recurring brain tumor that started as a grade 2 oligo 7 years ago. He had clean scans for 6 1/2 yrs. and then there it was. My questions has nothing to do with treatment issues, but of terminology. The drs. are using the term palitative treatment. I know what palitative treatment means, but what I want to know is if there is a certain criteria drs. use to determine when a patient is in palitative treatment? For example, GBM~s supposedly are not curable, is their treatment also palitative? Is palitative a term that is used with all malignant brain tumors or just certain stages of the disease? Thank you.

  (0.8510)   I have read that low grade astrocytomas will upgrade to a more aggressive form at some point in a patients life. However, I have been informed that pilocytic astrocytoma grade 1 can not progress to a grade 2. Since I have this kind of brain tumor (operation with only some removal due to position at the brain stem - medulla oblongata performed in May followed by radiation treatment in June/July, please let me know which information is correct. Also, you advised me to contact some major cener treating brain tumors. Can you reccomend me some of them. I am located in Croatia (so I would prefer Austria, Slovenia or Italy due to the distance) but any other location should not be a major problem. Thank you, Nat

  (0.8510)   My husband has had a headache for three weeks now. His memory has declined. His visual acuity has declined and is worse at night than in the day. His neck hurts and he can no longer do more than one thing at the time. He has had an MRI, lumbar puncture and CAT Scan. All are normal. The neurologist did not order an opening pressure reading when the lumbar puncture was done although he did acknowledge that my husband had many neurological symptoms. Now he tells us he doesn~t have a clue what is going on and that my husband may just have headaches like this forever. I can~t accept that. He has had headaches all of his life and his night vision he says has always been less clear than in the day. I think we need an opthamologist or another lumbar puncture with an opening pressure reading. Any advise?

  (0.8510)   In brain tumors, is number of nerve cells increase? Can brain tumors be heriditory? Is there any difference between tumor& cancer?

  (0.8510)   What are the symptoms




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