Glioblastoma Multiforme
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 For People with Newly Diagnosed Glioblastoma Multiforme
NovoCure Trial

The NovoTTF is a portable, investigational device for cancer treatment using Tumor Treating Fields. The device is used in addition to the standard treatments.

Trials and Noteworthy Treatments

  Previous 25 Treatment Next 25 Location Last Updated
Details Phase 2 Study of Azixa (MPC-6827) for the Treatment of Patients With Recurrent Glioblastoma Multiforme Los Angeles, CA
Stanford, CA
Chicago, IL
Boston, MA
Burlington, MA
Worcester, MA
Lebanon, NH
New York, NY 		08/11/2009
Details ABTC07-01-Phase I Trial of Aflibercept (VEGF Trap) with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients with Malignant Glioma San Francisco, CA 07/07/2009
Details PHASE II, single-arm, open-label investigation of HSPPC-96 vaccine with concurrent temozolomide in patients with newly diagnosed Glioblastoma Multiforme San Francisco, CA 07/07/2009
Details A Phase 2 Study of XL184 in Subjects with Progressive or Recurrent Glioblastoma Multiforme in First or Second Relapse San Francisco, CA
Charlottesville, VA 		06/29/2009
Details Phase II Clinical Trial of Hyperbaric Oxygenation in Conjunction with Radiotherapy and Temozolomide in Adults with Newly Diagnosed Glioblastoma Mineola, NY 06/18/2009
Details A Phase I Trial and Pharmacokinetic Study of Trabectedin (Yondelis®, ET-743) in Children and Adolescents With Relapsed or Refractory Solid Tumors Bethesda, MD 04/22/2009
Details A Phase I Trial of Enzastaurin (LY317615) in Combination With Carboplatin in Adults With Recurrent Gliomas Bethesda, MD 04/22/2009
Details A Phase I/II Trial of ZD6474 for Patients With Recurrent High-Grade and Progressive Low-Grade Gliomas Bethesda, MD 04/22/2009
Details Multiple Ascending Dose (MAD) Study of the IGF-1R Antagonist R1507 Administered as an Intravenous Infusion in Pediatric Patients With Advanced Solid Tumors. Bethesda, MD 04/22/2009
Details Phase II Trial of Tamoxifen and Bortezomib in Patients With Recurrent High-Grade Gliomas Bethesda, MD 04/22/2009
Details A Feasibility Assessment and a Phase I/II Trial of MLN518 (Tandutinib) for Treatment of Patients with Recurrent Glioblastoma Birmingham, AL
Tampa, FL
Atlanta, GA
Boston, MA
Baltimore, MD
Bethesda, MD
Detroit, MI
Winston-Salem, NC
Cleveland, OH
Philadelphia, PA 		04/21/2009
Details A Phase II Clinical Trial of the Histone Deacetylase Inhibitor Valproic Acid in Combination With Temodar and Radiation Therapy in Patients With High Grade Gliomas Bethesda, MD 04/21/2009
Details A Phase II Trial of Bevacizumab (avastin) and Irinotecan (CPT-11) for Patients With Recurrent High-Grade Gliomas Immediately Following Tumor Progression After Treatment With Bevacizumab Alone: A Companion Trial to NCI Study 06-C-0064 (Bevacizumab Alone for Recurrent Gliomas) Bethesda, MD 04/21/2009
Details A Phase II Trial of Enzastaurin in Combination With Bevacizumab in Adults With Recurrent Malignant Gliomas Bethesda, MD 04/21/2009
Details Phase II Trial of Bevacizumab (Avastin)for Patients With Recurrent High-Grade Glioma Bethesda, MD 04/21/2009
Details A Pharmacokinetic and Phase 2 Study of Sunitinib Malate in Recurrent Malignant Gliomas Toronto, Ontario, CANADA
Bethesda, MD
New York, NY
Cincinnati,, OH
Columbus, OH 		04/21/2009
Details An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-Grade Glioma Bethesda, MD 04/15/2009
Details Phase I Trial of Conditionally Replication-Competent Adenovirus (Delta-24-RGD4C) for recurrent malignant glioma Houston, TX 04/14/2009
Details A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas San Francisco, CA 04/06/2009
Details Phase III Randomized, Parallel Group, Multi-Centre Study in Recurrent Glioblastoma Subjects to Compare the Efficacy of AZD2171 [RECENTIN] Monotherapy and the Combination of AZD2171 with Lomustine to the Efficacy of Lomustine Alone Cincinnati, OH 04/06/2009
Details Phase I/II study of sorafenib with radiation and temozolomide in newly diagnosed glioblastoma or gliosarcoma Houston, TX 04/03/2009
Details Phase II study of CDX-110 with radiation and temozolomide in patients with newly diagnosed glioblastoma multiforme Houston, TX 04/03/2009
Details Phase III, randomised, parallel Group, multi-centre study in recurrent glioblastoma patients to compare the efficacy of cediranib monotherapy and the combination of cediranib with lomustine to the efficacy of lomustine alone Houston, TX 04/03/2009
Details Study of a Drug [DCVax®-Brain] to Treat Newly Diagnosed GBM Brain Cancer Los Angeles, CA
Tampa, FL
Chicago, IL
Ann Arbor, MI
Minneapolis, MN
Summit, NJ
Rochester, NY
Cleveland, OH
Columbus, OH
Dallas, TX 		03/15/2009
Details The GLASS-ART Trial: A Phase III Randomized Study of Neuradiab in Combination With External Beam Radiation and Temozolomide Versus External Beam Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme Los Angeles, CA
Tampa, FL
Durham, NC
Omaha, NE
New York, NY 		03/04/2009

News Stories

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  (0.7967)   What is your opinion on Dr Burzynskis antineoplaston therapy for brain tumors?

  (0.7967)   What is the survival time for a 63 year old male diagnosed with Glioblastoma Multiforme with Chemo and Radiation.

  (0.7967)   Glioblastoma Multiforme: What are the chances that a 14 year old will survive the diagnosis of glioblastoma multiforme?

  (0.7742)   My mother has been diagnosed with Glioblastoma Multiforme, tumor location: brain stem. She had a stereotactic biopsy and the doctor prescribed 40 radiation treatments with daily intake of Temodal 140mg. The radiation treatment clinic doesn~t work on weekends, so she goes 5 weekdays and pauses for 2 day week-end. However, the doctor told her to take Temodal even for week-ends till the rest of radiation treatment. That means that she would end up taking Temodal for 56 days! On the information sheet for Temodal, it is stated that Temodal should be taken for 42, up to 49 days max! Could you please tell me is it safe for my mother to take Temodal longer then 49 days? Is it safe to follow our doctor~s orders in continuing with Temodal until the end of 40 week-day radiation treatment (and end up taking Temodal for 56 days)? Should she continue taking Temodal on week-ends when she doesn~t go for radiation treatment?

  (0.7742)   My friend was diagonized in early May, 2004, with Glioblastoma Multiforme. He had surgery, radiation, and chemotherapy. After radiation, they did an MRI and it showed a new growth so he started the chemotherapy and, after four chemo treatments, they did another MRI and it had gotten bigger. They now want to do another surgery and try a different chemo. Are there any significant things we should worry about with the second surgery and, since it is still growing after radiation and chemotherapy, what are his chances of survival and how long?

  (0.7742)   What is the difference between diffuse astrocytoma grade three, a GBM, and AA grade three? Is it common for low white counts and low platelet counts to continually delay temodar treatments by a couple of weeks?

  (0.7742)   My 57-year-old brother has Glioblastoma Multiforme. He is on steroids and has been since Oct. Within the last five weeks, he has been bruising easily/bleeding on his lower arms and wrists. Does anyone know how this can be prevented? All he is done thus far is cover his lower arms with gauze! If someone could get back to me before 4:00 p.m. today, it would be greatly appreciated! Also, as long as we are on the subject, does anyone know of a doctor in New Jersey that is willing to work "outside the box" and supplement chemotherapy with additives, such as verapimil, tamoxifen, etc.?

  (0.7742)   My father was diagnosed with Glioblastoma Multiforme in mid-December 2003. The tumor is located in the left frontoparietal area and was thus deemed inoperable. He is about to begin the sixth and final week of radiation. He has also gone through first round of chemotherapy (Temador). During the course of his treatment he has been going to work daily. Over the course of the last five weeks, his right side mobility had improved substantially and his radio-oncologist expressed ~cautious optimism~ regarding his prognosis. However, just as he is to begin his six week of radiation he lost his balance twice and fell and has lost some of the movement in his right arm. My question is what can cause such deterioration of his neurological condition? Can it be explained by exhaustion, a side-effect of the treatment or that the treatment has not halted the tumor~s growth? Thank you very much.




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